1999

Perinatal listeriosis: a population-based multicenter study in Barcelona, Spain (1990-1996).
Am J Perinatol. 1998 Aug;15(8):461-7. Unique Identifier : AIDSLINE MED/99002693
Nolla-Salas J; Bosch J; Gasser I; Vinas L; de Simon M; Almela M; Latorre C; Coll P; Ferrer MD; Intensive Care Unit, Hospital del Mar, Autonomous University of; Barcelona, Spain.
The aim off this study was to describe the incidence, epidemiology, clinical presentation, and outcome of perinatal listeriosis for a 7-year period (1990-1996) based on data of an active population-based surveillance project implemented in the city of Barcelona, Spain . There were 30


Synthesis of substituted 2-ethoxycarbonyl- and 2-carboxyquinoxalin-3-ones for evaluation of antimicrobial and anticancer activity.
Farmaco. 1998 Jul 30;53(7):455-61. Unique Identifier : AIDSLINE MED/99053177
Sanna P; Carta A; Loriga M; Zanetti S; Sechi L; Istituto di Chimica Farmaceutica e Tossicologica, Sassari, Italy.
A series of variously substituted quinoxalin-3-ones bearing an ethoxycarbonyl or carboxy group in the C-2 position has been prepared and their structures proved by 1H NMR spectroscopy. The obtained compounds were investigated in vitro for antimicrobial and anticancer activities. Preliminary results showed a moderate a


Synthesis, structure elucidation and antimicrobial activity of some 3-hydroxy-2-naphthoic acid hydrazide derivatives.
Farmaco. 1998 Jul 30;53(7):462-7. Unique Identifier : AIDSLINE MED/99053178
Dogan HN; Rollas S; Erdeniz H; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Marmara; University, Istanbul, Turkey.
In this study, some 1,4-disubstituted thiosemicarbazide, 1,2,4-triazole and 1,3,4-thiadiazole type novel compounds derived from 3-hydroxy-2-naphthoic acid hydrazide were synthesized to screen for their antimicrobial activity. The structures of these substances were elucidated using elemental analysis and UV, 1H NMR, a


Evaluation of anti-HIV activity of 5-(2-phenyl-3'-indolal)-2-thiohydantoin.
Farmaco. 1998 Jul 30;53(7):525-7. Unique Identifier : AIDSLINE MED/99053185
Suzen S; Buyukbingol E; Department of Pharmaceutical Chemistry, Faculty of Pharmacy; (ECZACILIK), Ankara University, Turkey.
The anti-HIV activity of the previously synthesized 5-(2-phenyl-3 -indolal)-2-thiohydantoin I was evaluated. The compound, containing two structural moieties found in highly active anti-HIV agents, exhibited poor activity and rather high cytotoxicity.


Quarterly Communicable Disease Review January to March 1998. From the PHLS Communicable Disease Surveillance Centre.
J Public Health Med. 1998 Sep;20(3):359-64. Unique Identifier : AIDSLINE MED/99010318
PHS recommendations for the management of health-care worker exposures to HIV--Part 2.
Oncology (Huntingt). 1998 Oct;12(10):1447-9, 1453-4, 1457 passim. Unique Identifier : AIDSLINE MED/99014933
Major surgery seems not to influence HIV disease progression in haemophilia patients.
Br J Haematol. 1998 Oct;103(1):10-4. Unique Identifier : AIDSLINE MED/99006768
Astermark J; Lofqvist T; Schulman S; Stigendal L; Lethagen S; Nilsson IM; Berntorp E; Department of Coagulation Disorders, University of Lund,; University Hospital, Malmo, Sweden.
The influence of major surgery on HIV disease progression and decline in CD4+ cell count was evaluated in 23 seropositive haemophilia patients. 24 HIV-infected patients served as non-operated controls. In addition, 32 age-matched seronegative subjects were included. The follow-up time was up to 5 years. During the cou


Patterns of cytokine expression in AIDS-related non-Hodgkin's lymphoma.
Br J Haematol. 1998 Oct;103(1):143-9. Unique Identifier : AIDSLINE MED/99006787
Pastore C; Gaidano G; Ghia P; Fassone L; Cilia AM; Gloghini A; Capello D; Buonaiuto D; Gonella S; Roncella S; Carbone A; Saglio G; Dipartimento di Scienze Cliniche e Biologiche, Ospedale San; Luigi, Universita di Torino, Orbassano-Torino, Italy.
The pathogenesis of AIDS-related non-Hodgkin s lymphomas (AIDS-NHL) involves accumulation of genetic lesions, stimulation and selection by antigen, as well as infection by viruses. Deregulation of cytokine loops has also been proposed to contribute to AIDS-NHL development, although data are available only for a limite


B-cell chronic lymphocytic leukaemia with CD8 expression: report of 10 cases and immunochemical analysis of the CD8 antigen.
Br J Haematol. 1998 Oct;103(1):157-62. Unique Identifier : AIDSLINE MED/99006789
Mulligan SP; Dao LP; Francis SE; Thomas ME; Gibson J; Cole-Sinclair MF; Wolf M; Department of Haematology, Concord Hospital, Sydney, Australia.
We report 10 cases of B-cell chronic lymphocytic leukaemia (B-CLL) with expression of the T-cell antigen CD8. The majority of patients had typical B-cell CLL with stable and non-progressive stage A(O) disease except for more common expression of lambda light chain and CD25. Two patients had progressive disease and req


Th1/Th2 balance alteration in the clinical course of a patient with pure red cell aplasia and thymoma.
Br J Haematol. 1998 Nov;103(2):308-10. Unique Identifier : AIDSLINE MED/99043599
Fujisao S; Tsuda H; Division of Clinical Haematology and Immunology, Kumamoto City; Hospital, Kumamoto, Japan.
Peripheral T helper subsets in a patient with acquired pure red cell aplasia (PRCA) and thymoma were analysed by flow cytometry. Thymectomy resulted in a transient but definite improvement in anaemia. A continuous remission was attained by cyclosporin A (CsA) therapy. The changes in Th1/Th2 ratios corresponded with th


IFN-gamma-secreting Th cells regulate both the frequency and avidity of epitope-specific CD8+ T lymphocytes induced by peptide immunization: an ex vivo analysis.
Int Immunol. 1998 Sep;10(9):1273-9. Unique Identifier : AIDSLINE MED/99000392
Romieu R; Baratin M; Kayibanda M; Guillet JG; Viguier M; INSERM U445, Institut Cochin de Genetique Moleculaire,; Universite Rene Descartes, Paris, France.
CD8+ T lymphocytes are involved in protective immune responses to infected or tumor cells. In this report, we examined the regulation of antigen-specific CD8+ T cell frequency and avidity by distinct Th cell subsets. Peptide-specific CD8+ T cells were induced by immunization of mice with a MHC class I-restricted epito


Age-related modifications of the human alphabeta T cell repertoire due to different clonal expansions in the CD4+ and CD8+ subsets.
Int Immunol. 1998 Sep;10(9):1281-8. Unique Identifier : AIDSLINE MED/99000393
Wack A; Cossarizza A; Heltai S; Barbieri D; D'Addato S; Fransceschi C; Dellabona P; Casorati G; Unita d'Immunochimica, DIBIT, Istituto Scientifico H. San; Raffaele, Milano, Italy.
We have studied the effects of a life-long antigen stimulation on the clonal heterogeneity of human peripheral T cell subsets, as defined by their CD45 isoform expression. CD4+ or CD8+ T cells were obtained from healthy donors ranging in age from 20 to 100 years, and sorted into CD45RA+ and CD45RO+ populations. A modi


Differential localization of Th1 and Th2 cells in autoimmune gastritis.
Unique Identifier : AIDSLINE MED/99000398
Katakai T; Mori KJ; Masuda T; Shimizu A
The vast majority of CD4+ T cells infiltrating into gastric mucosa (GM) and in the draining (gastric) lymph node (GLN) shows an activated/memory phenotype, CD45RB(low) L-selectin(low) CD44(high), in neonataly thymectomized BALB/c mice bearing autoimmune gastritis (AIG), indicating that these cells are actively involve


In vitro positive selection and anergy induction of class II-restricted TCR transgenic thymocytes by a cortical thymic epithelial cell line.
Int Immunol. 1998 Sep;10(9):1335-46. Unique Identifier : AIDSLINE MED/99000399
Nelson AJ; Clegg CH; Farr AG; Department of Biological Structure, University of Washington,; Seattle, USA.
Thymic epithelial cell lines isolated from hyperplastic thymi of transgenic mice over-expressing human papilloma viral oncogenes E6 and E7 constitutively displayed a phenotype consistent with a cortical origin. Exposure to IFN-gamma induced class II MHC and ICAM-1 expression, and up-regulated expression of VCAM-1 and


The human immunodeficiency virus (HIV)-type 1 coreceptor CXCR-4 (fusin) is preferentially expressed on the more immature CD34+ hematopoietic stem cells.
Ann Hematol. 1998 Nov;77(5):193-7. Unique Identifier : AIDSLINE MED/99073854
Viardot A; Kronenwett R; Deichmann M; Haas R; Department of Internal Medicine V, University of Heidelberg,; Germany.
In synergy with the CD4 antigen, the chemokine receptor CXCR-4 functions as a coreceptor for T-cell-tropic HIV-1 strains. Using two- and three-color immunofluorescence analysis, we examined the expression of CXCR-4 on CD34+ cells in 21 samples obtained from leukapheresis (LP) products of cancer patients who underwent


Antiviral therapy in a child with pediatric human immunodeficiency virus (HIV): case study of audiologic findings.
J Am Acad Audiol. 1998 Aug;9(4):292-8. Unique Identifier : AIDSLINE MED/98402075
Christensen LA; Morehouse CR; Powell TW; Alchediak T; Silio M; Department of Communication Disorders, Louisiana State University; Medical Center, New Orleans 70112, USA.
Over the past decade, much research has been conducted to determine the auditory consequences of human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS). This research, primarily using adult patients, has focused on the involvement of the central auditory nervous system (CANS). Meas


The ethics of placebo-controlled trials for perinatal transmission of HIV in developing countries [see comments]
J Clin Ethics. 1998 Summer;9(2):156-66. Unique Identifier : AIDSLINE MED/98423561
Clark PA; Department of Theology, St. Joseph's University, Philadelphia,; PA, USA.
The "best proven therapeutic method" standard in clinical trials in technologically developing countries [see comments]
J Clin Ethics. 1998 Summer;9(2):167-72. Unique Identifier : AIDSLINE MED/98423562
Levine RJ; Yale University School of Medicine, New Haven, CT, USA.
Deconstructing equity, autonomy, and ethical analysis [comment]
J Clin Ethics. 1998 Summer;9(2):99-107. Unique Identifier : AIDSLINE MED/98423555
Howe EG; Uniformed Services University of the Health Sciences, Bethesda,; MD, USA.
HIV infection linked to substance use among hospitalized patients with severe mental illness.
Psychiatr Serv. 1998 Oct;49(10):1269. Unique Identifier : AIDSLINE MED/98451173
McKinnon K; Cournos F; Department of Psychiatry, Columbia University College of; Physicians and Surgeons and New York State Psychiatric Institute,; USA. kmm49@columbia.edu
Endogenous retroviruses and multiple sclerosis. II. HERV-7q.
C R Acad Sci III. 1998 Oct;321(10):857-63. Unique Identifier : AIDSLINE GENBANK/A60201
Alliel PM; Perin JP; Pierig R; Nussbaum JL; Menard A; Rieger F; Inserm, Paris, France.
The search for new endogenous retroviral sequences, on the basis of sequence homologies with the pol gene of the recently reported multiple sclerosis associated retrovirus (MSRV), allowed us to identify a full length endogenous retrovirus sequence located on the long arm of human chromosome 7. This retrovirus, HERV-7q


The risk of serious odontogenic infections in HIV-positive patients: a pilot study.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998 Oct;86(4):406-9. Unique Identifier : AIDSLINE MED/99014956
Miller EJ Jr; Dodson TB; Department of Oral/Maxillofacial Surgery, Boston, MA 02114, USA.; tdodson@partners.org
OBJECTIVE: The purpose of this study was to perform a preliminary test of the hypothesis that patients infected with the human immunodeficiency virus (HIV) have an increased risk for serious odontogenic infections in comparison with HIV-negative patients. STUDY DESIGN: To address the research purpose, we used a case-c


Reduced chlamydial infection and gonorrhea among commercial sex workers in Fukuoka City, Japan.
Int J Urol. 1998 Sep;5(5):471-5. Unique Identifier : AIDSLINE MED/98452697
Tanaka M; Nakayama H; Sakumoto M; Takahashi K; Nagafuji T; Akazawa K; Kumazawa J; Department of Urology, Faculty of Medicine, Kyushu University,; Fukuoka, Japan.
BACKGROUND: Until recently, epidemiologic studies of sexually transmitted diseases (STDs), including human immunodeficiency virus type-1 (HIV-1) infection, among Japanese female commercial sex workers and their patterns of condom use have been rare. We investigated trends in STDs among female commercial sex workers an


Immunological analysis of rat renal transplant recipients exhibiting long-term survival following treatment with 15-deoxyspergualin in the early postoperative phase.
Int J Urol. 1998 Sep;5(5):476-81. Unique Identifier : AIDSLINE MED/98452698
Takeuchi I; Chikaraishi T; Seki T; Kanagawa K; Koyanagi T; Department of Urology, Hokkaido University School of Medicine,; Sapporo, Japan.
BACKGROUND: We previously reported that short-term administration of 15-deoxyspergualin (DSG), 5 mg/kg/day on postoperative days 4 through 7, prolonged survival of rat renal allografts indefinitely. We now report the immunologic environment of DSG-treated recipients in the early postoperative phase. METHODS: TO (RT1u)


Social network ties, self-efficacy, and condom use among women who use crack cocaine: a pilot study.
Subst Use Misuse. 1998 Aug;33(10):2049-73. Unique Identifier : AIDSLINE MED/98416091
Montoya ID; Affiliated Systems Corporation, Our Lady of the Lake University,; Houston, Texas 77027-6022, USA. ASC@Phoenix.Net
So far, attempts to change the sexual risk behavior of women who use crack cocaine have been less successful than efforts to change the needle risk behavior of injection drug users. Two theoretical areas that have shown some success in predicting behavior change among of out-of-treatment drug users are Bandura s socia


Performance of antenatal HIV screening strategies in the United Kingdom.
J Med Screen. 1998;5(3):133-6. Unique Identifier : AIDSLINE MED/99011965
Tookey PA; Gibb DM; Ades AE; Duong T; Masters J; Sherr L; Peckham CS; Hudson CN; Department of Epidemiology and Public Health, Institute of Child; Health, London, United Kingdom.
BACKGROUND: In 1996 only 13.5% of previously undiagnosed HIV infected women were detected in pregnancy. In this study, all 265 maternity units in the United Kingdom were surveyed to determine the relation between screening strategy, uptake of testing, and detection rate. METHODS: Data


Neomycin B inhibits splicing of the td intron indirectly by interfering with translation and enhances missplicing in vivo.
RNA. 1998 Dec;4(12):1653-63. Unique Identifier : AIDSLINE MED/99063406
Waldsich C; Semrad K; Schroeder R; Institute of Microbiology and Genetics, University of Vienna,; Austria.
The aminoglycoside antibiotic neomycin B inhibits translation in prokaryotes and interferes with RNA-protein interactions in HIV both in vivo and in vitro. Hitherto, inhibition of ribozyme catalysis has only been observed in vitro. We therefore monitored the activity of neomycin B and several other aminoglycoside anti


Summer-type hypersensitivity pneumonitis. T-cell receptor V gene usage in BALF T-cells from 3 cases in one family.
Sarcoidosis Vasc Diffuse Lung Dis. 1998 Sep;15(2):173-7. Unique Identifier : AIDSLINE MED/99006325
Shigematsu M; Nagai S; Nishimura K; Izumi T; Eklund AG; Grunewald J; Department of Pulmonary Medicine, Kyoto University, Japan.
BACKGROUND AND AIM OF THE WORK: Hypersensitivity pneumonitis (HP) is a granulomatous lung disease characterized by a T lymphocyte bronchiolalveolitis and in several recent studies the preferential use of V beta regions of T-cell receptor (TCR) has been demonstrated. In Japan , summer


A case of sarcoidosis with increased response of peripheral blood mononuclear cells to purified protein derivative antigen after depletion of CD8+ T-cells in vitro [letter]
Sarcoidosis Vasc Diffuse Lung Dis. 1998 Sep;15(2):194-5. Unique Identifier : AIDSLINE MED/99006332
Ishioka S; Hiyama K; Hozawa S; Maeda A; Maeda H; Yamakido M
Reliability of the timeline follow-back sexual behavior interview.
Ann Behav Med. 1998 Winter;20(1):25-30. Unique Identifier : AIDSLINE MED/98427923
Weinhardt LS; Carey MP; Maisto SA; Carey KB; Cohen MM; Wickramasinghe SM; Department of Psychology, Syracuse University, NY 13244-2340,; USA.
The reliability of self-reported sexual behavior is a question of utmost importance to human immunodeficiency virus (HIV) prevention research. The Timeline Follow-Back (TLFB) interview, which was developed to assess alcohol consumption on the event level, incorporates recall-enhancing techniques that result in reliabl


Human herpes virus 8 (HHV-8) in Kaposi's sarcoma: lack of association with Bcl-2 and p53 protein expression.
Unique Identifier : AIDSLINE MED/99067325
Kennedy MM; O'Leary JJ; Oates JL; Lucas SB
HHV-8 is not associated with follicular dendritic cell tumours.
Unique Identifier : AIDSLINE MED/99067328
Nayler SJ; Taylor L; Cooper K
Follicular dendritic cell tumours are rare malignancies derived from the follicular dendritic cells of lymphoid follicles. These tumours have been associated with Epstein-Barr virus infections and with the hyaline vascular subtype of Castleman s disease. Because many examples of Castleman s disease have been associate


[Study of the reasons for spread of communicable diseases]
Chung Hua Liu Hsing Ping Hsueh Tsa Chih. 1997 Apr;18(2):102-5. Unique Identifier : AIDSLINE MED/99029053
Wei CY
[Communicable disease control in China]
Chung Hua Liu Hsing Ping Hsueh Tsa Chih. 1997 Apr;18(2):106-8. Unique Identifier : AIDSLINE MED/99029054
Zeng G; Zhang JK; Zhang Y; Xu C; Rou KM; Cheng YK
[Challenges for the prevention of communicable diseases (editorial)]
Chung Hua Liu Hsing Ping Hsueh Tsa Chih. 1997 Apr;18(2):67-9. Unique Identifier : AIDSLINE MED/99029042
Zeng G; Wei CY
[The influence to the function of cellular immunity after being infected by HBV in the PBMC in chronic hepatitis B]
Chung Hua Liu Hsing Ping Hsueh Tsa Chih. 1997 Apr;18(2):80-2. Unique Identifier : AIDSLINE MED/99029046
Xuan SY; Sun Y; Zhang J; Department of Infections Disease, Qingdao Municipal Hospital.
In this study, HBV DNA was detected by PCR from PBMC of chronic hepatitis B. A total number of 54 cases were positive and 71 cases were negative. When detecting the competence of NK cells, the subgroup of T cells the ratio of CD4/CD8, the concentration of sIL-2R in three groups, and between the two CHB groups and a no


[A cohort study of HIV infection among intravenous drug users in Ruili and other two counties in Yunnan Province, China, 1992-1995]
Chung Hua Liu Hsing Ping Hsueh Tsa Chih. 1997 Oct;18(5):259-62. Unique Identifier : AIDSLINE MED/99029027
Zheng X; Zhang JP; Qu SQ; Institute of Epidemiology and Microbiology, Chinese Academy of; Preventive Medicine, Beijing.
Since 1992, cohort study of prevaience of HIV infection and incidence rate among drug users has been conducted annually at the study spots along southwestern border areas of Ruili, Longchuan and Luxi counties, Yunnan province of China . From 1992 to 1995, 859, 437, 343 and 540 drug u


[New infectious diseases: occurrence and preventive strategies]
Chung Hua Liu Hsing Ping Hsueh Tsa Chih. 1997 Oct;18(5):306-8. Unique Identifier : AIDSLINE MED/99029040
Zhang XT
[Molecular epidemiology of HIV infection]
Chung Hua Liu Hsing Ping Hsueh Tsa Chih. 1997 Oct;18(5):309-11. Unique Identifier : AIDSLINE MED/99029041
Yin TM
Host control of HIV-1 parasitism in T cells by the nuclear factor of activated T cells.
Unique Identifier : AIDSLINE MED/99059495
Kinoshita S; Chen BK; Kaneshima H; Nolan GP; Department of Molecular Pharmacology, Stanford University School; of Medicine, California 94305, USA.
Post HIV-1 entry, productive HIV-1 infection of primary T cells requires overcoming several cellular blocks to provirus establishment and replication. Activation of unknown host intracellular events overcomes such inhibitory steps and is concomitant with HIV-1 replication. We show that the transcription factor NFATc w


Treatment of human immunodeficiency virus-positive patients with complementary and alternative medicine: a survey of practitioners.
Unique Identifier : AIDSLINE MED/98435796
Calabrese C; Wenner CA; Reeves C; Turet P; Standish LJ
OBJECTIVE: To investigate complementary and alternative medicine (CAM) practices provided to human immunodeficiency virus (HIV)-infected individuals, provider experience in HIV disease,


Expression of mouse mammary tumor virus-like env gene sequences in human breast cancer.
Clin Cancer Res. 1998 Oct;4(10):2565-8. Unique Identifier : AIDSLINE MED/99011016
Wang Y; Go V; Holland JF; Melana SM; Pogo BG; Department of Pathology, Mount Sinai School of Medicine, New; York, New York 10029, USA.
We have reported previously (Wang et al, Cancer Res., 55: 5173-5179, 1995) the presence of a 660-bp sequence that is 90-98% homologous to the env gene of mouse mammary tumor virus in 38% of 314 unselected breast cancer samples, in some breast cancer cell lines, and in 1.8% of the 107 normal breast specimens from reduc


Correspondence re: S. M. Melana et al., Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by 3'-azido-3'-deoxythymidine. Clin. Cancer Res., 4: 693-696, 1998 [letter]
Clin Cancer Res. 1998 Oct;4(10):2569-70. Unique Identifier : AIDSLINE MED/99011017
Olivero OA; Gomez DE
Non-Hodgkin's lymphoma risk derived from exposure to organic solvents: a review of epidemiologic studies.
Cad Saude Publica. 1998;14 Suppl 3:41-66. Unique Identifier : AIDSLINE MED/99051486
Rego MA; Centro de Estudos da Saude do Trabalhador--CESAT, Rua Pedro; Lessa 123, Canela, 40.110-050, Salvador, Bahia, Brasil.; mrego@lognet.com.br
The rate of non-Hodgkin s lymphomas (NHL) has increased around the world during the last decades. Apart from the role of the human immunodeficiency virus (HIV) infection in the development of NHL, exposure to chemical agents like phenoxyacetic pesticides, hair dyes, metal fumes and organic solvents are suspected to be


The role of neuroendocrine immune interactions in the initiation of humoral immunity in chickens.
Domest Anim Endocrinol. 1998 Sep;15(5):409-22. Unique Identifier : AIDSLINE MED/99001224
Mashaly MM; Trout JM; Hendricks G 3rd; al-Dokhi LM; Gehad A; Department of Poultry Science, Pennsylvania State University,; University Park 16802, USA.
The presence of neuroendocrine immune interaction in mammalian species has been studied extensively and has been established. However, such an interaction is not as well established in avian species. Furthermore, the role of such an interaction in the initiation of humoral immunity is not well understood. Therefore, t


Farmed deer: a large animal model for stress.
Domest Anim Endocrinol. 1998 Sep;15(5):445-56. Unique Identifier : AIDSLINE MED/99001228
Griffin JF; Thomson AJ; Department of Microbiology, University of Otago, Dunedin, New; Zealand.
In the early classic period it was suggested by Heracleitus that a static unchanged state was not the natural condition, but rather that the capacity to undergo constant change was intrinsic to all living things. After that, Empedoeles, circa 500 BC, proposed that for living organisms to survive they require a harmoni


[Polyneuropathies of pregnancy. Clinical neurophysiological, and anatomo-pathological study apropos of 38 cases collected at the Neurology Clinic of the the Fann University Hospital Center]
Dakar Med. 1996;41(1):47-54. Unique Identifier : AIDSLINE MED/99044331
Thiam A; Abd-Ali G; Ndiaye MM; Diagne M; Ndiaye IP; Clinique Neurologique de Fann, Dakar.
Authors are studying the clinical, electrophysiological, and anatomical aspects of polyneuropathies of 28 observations in Clinic Neurologic of Fann, the onset occurred in pregnancy. Relations with Tropical Neuro-myelopathies (TNM) are emphasized. 28 observations concerning young women between 17 and 35 years old, the


[Progressive noma: apropos of 27 cases seen at the National Hospital Center of Ouagadougou]
Dakar Med. 1998;43(1):45-8. Unique Identifier : AIDSLINE MED/99044396
Ouoba K; Sanou I; Dao M; Kam L; Ouedraogo A; Ouedraogo R; Sawadogo A; Service ORL, CHN Yalgado Ouedraogo, Ouagadougou, Burkina Faso.
This retrospective study objects to report epidemiological profile, clinical display and take care of progressive noma at the National Hospital Center of Ouagadougou. We assign the term noma to the gangrenous gingivo-stomatitis occurring in a prone environment, leading in a few days into a sharp ulcer in the soft part


[New HIV-1 variant discovered in Cameroon (news)]
Dtsch Med Wochenschr. 1998 Nov 20;123(47):A7. Unique Identifier : AIDSLINE MED/99073340
Kowalski A
[HIV infection as an occupational disease in a hospital physician. Decision of the Federal Social Court 18 November 1997]
Dtsch Med Wochenschr. 1998 Nov 27;123(48):1461. Unique Identifier : AIDSLINE MED/99076052
Rieger HJ
Rosai-Dorfman disease (extranodal sinus histiocytosis) in a patient with HIV.
Ear Nose Throat J. 1998 Oct;77(10):855-8. Unique Identifier : AIDSLINE MED/99035944
Perry BP; Gregg CM; Myers S; Lilly S; Mann KP; Prieto V; Division of Otolaryngology-Head and Neck Surgery, Duke University; Medical Center, Durham, North Carolina, USA.
Rosai-Dorfman disease, or sinus histiocytosis with massive lymphadenopathy (SHML), is a rare histiocytosis of unknown etiology that most commonly involves the cervical lymph nodes. Extranodal involvement occurs in 30-40% of cases, most often in the head and neck. Characteristic histologic findings include emperiopolese


De novo status epilepticus as the presenting sign of neurosyphilis.
Epilepsia. 1998 Dec;39(12):1367-9. Unique Identifier : AIDSLINE MED/99075419
Primavera A; Solaro C; Cocito L; Department of Neurological Sciences, University of Genova, Italy.
Although the incidence of seizures in neurosyphilis ranges from 14 to 60%, status epilepticus (SE) as a presenting complaint of neurosyphilis is definitely rare. A 44-year-old human immunodeficiency virus (HIV)-negative man with no history of epilepsy suddenly presented with acute mental confusion and was diagnosed ase


Long-term effects of HIV counseling and testing for women: behavioral and psychological consequences are limited at 18 months posttest.
Health Psychol. 1998 Sep;17(5):395-402. Unique Identifier : AIDSLINE MED/98446892
Ickovics JR; Druley JA; Grigorenko EL; Morrill AC; Beren SE; Rodin J; Department of Epidemiology and Public Health, Yale University,; New Haven, Connecticut 06520-8034, USA.; jeannette.ickovics@yale.edu
Behavioral and psychological consequences of HIV counseling and testing (HIV C&T) for women were examined in a longitudinal, prospective study. Women who received HIV C&T at community health clinics (n = 106) and a comparison group of never-tested women (n = 54) were interviewed five times over 18 months. There


HIV sexual risk behavior following bereavement in gay men.
Health Psychol. 1998 Sep;17(5):403-11. Unique Identifier : AIDSLINE MED/98446893
Mayne TJ; Acree M; Chesney MA; Folkman S; Department of Psychology, New York University, New York; 10003-6634, USA. mayne@psych.nyu.edu
The present study followed a group of 100 gay men up to 1 year before and 1 year after losing a partner to AIDS (University of California, San Francisco Coping Project). Following bereavement, participants were at increased risk for engaging in unprotected anal intercourse: at 4 to 6 months for HIV-negative men and at


Number of pregnancies, outcome expectancies, and social norms among HIV-infected young women.
Health Psychol. 1998 Sep;17(5):470-5. Unique Identifier : AIDSLINE MED/98446901
Murphy DA; Mann T; O'Keefe Z; Rotheram-Borus MJ; Department of Psychiatry, Neuropsychiatric Institute, University; of California, Los Angeles, 90024, USA. dmurphy@mednet.ucla.edu
In this descriptive study, researchers examined pregnancies, sexually transmitted diseases (STDs), and sexual behaviors among 67 HIV-infected young women, as well as the women s outcome expectancies and peer and partner norms regarding pregnancy. Many of the women (69%) had been pregnant; 42% had been pregnant at leas


Lipophosphoglycan of Leishmania donovani inhibits lipid vesicle fusion induced by the N-terminal extremity of viral fusogenic simian immunodeficiency virus protein.
Eur J Biochem. 1998 Nov 15;258(1):150-6. Unique Identifier : AIDSLINE MED/99067029
Martin I; Turco SJ; Epand RM; Ruysschaert JM; Laboratoire de Chimie-Physique des Macromolecules aux Interfaces; (LCPMI) CP206/2, Universite Libre de Bruxelles, Brussels,; Belgium. imartin@ulb.ac.be
Lipophosphoglycan (LPG), the major glycoconjugate of Leishmania parasites, was recently shown to be a potent inhibitor of viral infection. The mechanism by which this natural membrane amphiphile compound inhibits membrane fusion was investigated in this study using a simple model membrane system and a synthetic peptid


Rapid analysis of epitope-paratope interactions between HIV-1 and a 17-amino-acid neutralizing microantibody by electrospray ionization mass spectrometry.
Eur J Biochem. 1998 Nov 15;258(1):164-9. Unique Identifier : AIDSLINE MED/99067031
Millar AL; Jackson NA; Dalton H; Jennings KR; Levi M; Wahren B; Dimmock NJ; Department of Biological Sciences, University of Warwick,; Coventry, UK.
Progress in therapeutic or prophylactic immune intervention in HIV-1 infections may only come about with a detailed understanding at the molecular/atomic level of how antibodies neutralize (inactivate) virus infectivity. Currently information on the molecular aspects of antibody-virus interaction comes predominantly f


Anthropometric indicators of human immunodeficiency virus infection in infants with early and late symptoms in the first months of life.
Eur J Pediatr. 1998 Oct;157(10):811-3. Unique Identifier : AIDSLINE MED/99025691
Agostoni C; Riva E; Gianni ML; Silano M; Giovannini M; Zuccotti GV; Department of Paediatrics, San Paolo Hospital, Milano, Italy.; agostoc@tin.it
Standardised growth indices (Z-scores of weight-for-age, WA, length-for-age, LA, weight-for-length, WL, according to the reference data of the World Health Organization ) have been compared for the first 4 months of life among 119 infants born to mothers affected by the type-1 human imm


Th2 cytokines exert a dominant influence on epithelial cell expression of the major group human rhinovirus receptor, ICAM-1.
Eur Respir J. 1998 Sep;12(3):619-26. Unique Identifier : AIDSLINE MED/98433754
Bianco A; Sethi SK; Allen JT; Knight RA; Spiteri MA; Dept of Respiratory Medicine, North Staffordshire Hospital Trust,; UK.
Intercellular adhesion molecule (ICAM)-1 is a cell receptor important in both human rhinovirus (HRV) attachment and immune effector cell mobilization. The level of expression of ICAM-1 by epithelial cells (EC) therefore plays a crucial role in the intricate biological phenomena underlying viral binding, host infection


Infectious Th1 and Th2 autoimmunity in diabetes-prone mice.
Immunol Rev. 1998 Aug;164:119-27. Unique Identifier : AIDSLINE MED/99011862
Tian J; Olcott AP; Hanssen LR; Zekzer D; Middleton B; Kaufman DL; Department of Molecular and Medical Pharmacology, University of; California, Los Angeles 90095-1735, USA.
In the non-obese diabetic (NOD) mouse, a Th1-biased autoimmune response arises spontaneously against glutamic acid decarboxylase, concurrent with the onset of insulitis. Subsequently, Th1-type autoreactivity spreads intra- and intermolecularly to other beta-cell autoantigens (beta CAAs), suggesting that a spontaneous


Immune focusing vs diversification and their connection to immune regulation.
Immunol Rev. 1998 Aug;164:5-10. Unique Identifier : AIDSLINE MED/99011850
Sercarz EE; Division of Immune Regulation, La Jolla Institute for Allergy &; Immunology, San Diego, CA 92121, USA. eli@liai.org
Cloning and sequencing of yajC and secD homologs of Brucella abortus and demonstration of immune responses to YajC in mice vaccinated with B. abortus RB51.
Infect Immun. 1998 Dec;66(12):5684-91. Unique Identifier : AIDSLINE GENBANK/AF085217
Vemulapalli R; Duncan AJ; Boyle SM; Sriranganathan N; Toth TE; Schurig GG; Center for Molecular Medicine and Infectious Diseases, Department; of Biomedical Sciences and Pathobiology, VA-MD Regional College; of Veterinary Medicine, Virginia Polytechnic Institute and State; University, Blacksburg, Virginia 24061-0342, USA.
To identify Brucella antigens that are potentially involved in stimulating a protective cell-mediated immune response, a gene library of Brucella abortus 2308 was screened for the expression of antigens reacting with immunoglobulin G2a antibodies from BALB/c mice vaccinated with B. abortus RB51. One selected positive


Mycobacterial dose defines the Th1/Th2 nature of the immune response independently of whether immunization is administered by the intravenous, subcutaneous, or intradermal route.
Infect Immun. 1998 Dec;66(12):5743-50. Unique Identifier : AIDSLINE MED/99043899
Power CA; Wei G; Bretscher PA; Department of Microbiology, University of Saskatchewan,; Saskatoon, Saskatchewan S7N 5E5 Canada.
It is believed that cell-mediated immunity alone can contain Mycobacterium tuberculosis, the pathogen responsible for tuberculosis. The induction of antibody, or of a mixed cell-mediated/humoral response, is associated with tuberculous disease. It is therefore important to determine the conditions of immunization with


Role of NK cells in early host response to chlamydial genital infection.
Infect Immun. 1998 Dec;66(12):5867-75. Unique Identifier : AIDSLINE MED/99043917
Tseng CT; Rank RG; Department of Microbiology and Immunology, University of Arkansas; for Medical Sciences, Little Rock, Arkansas 72205, USA.
The cell-mediated immune response has been documented to be the major protective immune mechanism in mice infected genitally with the agent of mouse pneumonitis (MoPn), a biovar of Chlamydia trachomatis. Moreover, there is strong evidence to indicate that gamma interferon (IFN-gamma) is a major effector mechanism of t


Specific-antibody-secreting cells in the rectums and genital tracts of nonhuman primates following vaccination.
Infect Immun. 1998 Dec;66(12):5889-96. Unique Identifier : AIDSLINE MED/99043920
Eriksson K; Quiding-Jarbrink M; Osek J; Moller A; Bjork S; Holmgren J; Czerkinsky C; Department of Medical Microbiology and Immunology, University of; G oteborg, Goteborg, Sweden. Kristina.Eriksson@microbio.gu.se
To determine optimal strategies to induce specific-antibody-secreting cells (specific ASC) in the rectal and vaginal mucosae, we immunized monkeys with a prototype mucosal immunogen, cholera toxin (CT), given locally or via gastric or parenteral administration. Repeated rectal or vaginal CT immunizations induced stron


Reciprocal regulation of Th1- and Th2-cytokine-producing T cells during clearance of parasitemia in Plasmodium falciparum malaria.
Infect Immun. 1998 Dec;66(12):6040-4. Unique Identifier : AIDSLINE MED/99043944
Winkler S; Willheim M; Baier K; Schmid D; Aichelburg A; Graninger W; Kremsner PG; Department of Internal Medicine, Division of Infectious Diseases,; University of Vienna, Vienna, Austria.; stefan.winkler@akh-wien.ac.at
Flow cytometry for the intracellular detection of T-cell cytokines was performed for 15 Gabonese patients during acute uncomplicated Plasmodium falciparum malaria. A striking expansion of CD4(+) and CD8(+) T cells producing gamma interferon (IFN-gamma) was found during drug-induced clearance of parasitemia, paralleled


Lactobacilli and streptococci induce interleukin-12 (IL-12), IL-18, and gamma interferon production in human peripheral blood mononuclear cells.
Infect Immun. 1998 Dec;66(12):6058-62. Unique Identifier : AIDSLINE MED/99043948
Miettinen M; Matikainen S; Vuopio-Varkila J; Pirhonen J; Varkila K; Kurimoto M; Julkunen I; Department of Virology, National Public Health Institute, 00300; Helsinki, Finland. minja.miettinen@ktl.fi
Human peripheral blood mononuclear cells (PBMC) were stimulated with three nonpathogenic Lactobacillus strains and with one pathogenic Streptococcus pyogenes strain, and cytokine gene expression and protein production were analyzed. All bacteria strongly induced interleukin-1beta (IL-1beta), IL-6, and tumor necrosis f


Drug monitoring during the treatment of AIDS-associated Pneumocystis carinii pneumonia with trimethoprim-sulfamethoxazole.
Unique Identifier : AIDSLINE MED/99000041
Klinker H; Langmann P; Zilly M; Richter E
OBJECTIVE: To monitor trimethoprim and sulfamethoxazole plasma levels in patients with AIDS-associated Pneumocystis carinii pneumonia. METHOD: Trimethoprim-sulfamethoxazole steady-state plasma concentrations were measured by high-pressure liquid chromatography during 37 episodes of Pneumocystis carinii pneumonia in pa


Critical level and detection limit: performance measures for PCR-based assays.
J Virol Methods. 1998 Oct;74(2):139-48. Unique Identifier : AIDSLINE MED/98450893
Markert-Hahn C; Berding C; Kuhn C; Boehringer Mannheim GmbH, Department of New Technologies LP-DNS,; Penzberg, Germany.; christine_markert-hahn@bmg.boehringer-mannheim.com
In clinical diagnostic work, sensitivity and specificity are key assay features. In this note we introduce two clinically relevant statistical assay performance measures, the critical level (CL), and the detection limit (DL) for the PCR-based assay. To allow for easy access to these characteristics a Windows-based pro


Clinical evaluation and applications of the Amplicor HBV Monitor test, a quantitative HBV DNA PCR assay.
Unique Identifier : AIDSLINE MED/98450895
Gerken G; Gomes J; Lampertico P; Colombo M; Rothaar T; Trippler M; Colucci G
Viral load has emerged recently as a reliable marker of disease progression and therapeutic efficacy in chronic infections, including AIDS and hepatitis C. The clinical management of type B hepatitis could also be improved by monitoring viremia levels in patients with chronic liver disease undergoing anti-viral treatm


Female injecting drug users: human immunodeficiency virus risk behavior and intervention needs.
J Prof Nurs. 1998 Nov-Dec;14(6):361-9. Unique Identifier : AIDSLINE MED/99056139
Brown EJ; Center for Urban Health Research, School of Nursing, University; of Pennsylvania, Philadelphia 19104, USA.
Injecting drug use and heterosexual contact are the major exposure categories for women acquiring human immunodeficiency virus (HIV). The purpose of this study was to explore the relationship of acquired immunodeficiency syndrome (AIDS) risk perception, perceived seriousness of HIV, drug use self-efficacy, sexual self


Single amino acid change in DNA polymerase is associated with foscarnet resistance in a varicella-zoster virus strain recovered from a patient with AIDS.
J Infect Dis. 1998 Nov;178 Suppl 1:S55-7. Unique Identifier : AIDSLINE MED/99070077
Visse B; Dumont B; Huraux JM; Fillet AM; Laboratoire de Virologie, CERVI, Hopital Pitie-Salpetriere,; Paris, France.
The genetic characterization of a foscarnet-resistant strain of varicella-zoster virus (VZV) that was isolated from a patient with AIDS is reported. Compared with the sequence of the Dumas reference strain, this strain, which was isolated from a patient in whom foscarnet treatment failed, had two point mutations. The


Cytokine production in varicella-zoster virus-stimulated cultures of human blood lymphocytes.
J Infect Dis. 1998 Nov;178 Suppl 1:S95-8. Unique Identifier : AIDSLINE MED/99070086
Hayward AR; Cosyns M; Jones M; Levin MJ; Villanueba E; Weinberg A; Chan CY; Department of Pediatrics, University of Colorado School of; Medicine, Denver 80262, USA. anthony.hayward@uchsc.edu
Estimates of responder cell frequency (RCF) based on limiting dilution analyses are laborious, and alternative means to quantitate cell-mediated immunity to immunogens are desirable. It was shown that levels of interleukin (IL)-2 in the supernatant of varicella-zoster virus-stimulated blood lymphocytes from immune adu


[Etiology and therapy of secondary chronic glomerulonephritis]
Nippon Naika Gakkai Zasshi. 1998 Jul 10;87(7):1277-86. Unique Identifier : AIDSLINE MED/98417797
Sugisaki T
Bragdon vs. Abbott [editorial]
J Mich Dent Assoc. 1998 Sep;80(7):12. Unique Identifier : AIDSLINE MED/99080801
Chase WR
HAART and host: balancing the response to HIV-1. Highly active antiretroviral therapy [news]
Lancet. 1998 Nov 21;352(9141):1686. Unique Identifier : AIDSLINE MED/99068342
Morris K
Ghost of AIDS musical returns to haunt South Africa's health minister [news]
Lancet. 1998 Nov 21;352(9141):1688. Unique Identifier : AIDSLINE MED/99068344
Baleta A
Popular drama prompts interest in HIV in Japan [news]
Lancet. 1998 Dec 5;352(9143):1840. Unique Identifier : AIDSLINE MED/99066724
Watts J
Treating HIV/AIDS information overload.
Lancet. 1998 Dec 5;352(9143):1866. Unique Identifier : AIDSLINE MED/99066750
Morris K; The Lancet, London, UK.
Three new drugs for HIV infection.
Med Lett Drugs Ther. 1998 Dec 4;40(1041):114-6. Unique Identifier : AIDSLINE MED/99071731
Oral manifestations of HIV disease.
Mt Sinai J Med. 1998 Oct-Nov;65(5-6):322-32. Unique Identifier : AIDSLINE MED/99060349
Sirois DA; Department of Oral Pathology, Biology, and Diagnostic Sciences,; New Jersey Dental School, University of Medicine and Dentistry of; New Jersey, Newark 07103, USA.
Oral disease is frequently associated with HIV. While nearly all oral disorders associated with HIV infection also occur in other conditions characterized by immunosuppression, no other condition is associated with as wide and significant a spectrum of oral disease as is HIV infection. Many HIV-associated oral disorde


Transmission of infectious disease in the dental setting.
Mt Sinai J Med. 1998 Oct-Nov;65(5-6):378-82. Unique Identifier : AIDSLINE MED/99060356
Heir J; Ziccardi VB; Department of Oral and Maxillofacial Surgery, New Jersey Dental; School, University of Medicine and Dentistry of New Jersey,; Newark 07103-2400, USA.
Patients in the industrialized world are at low risk of acquiring nosocomial infections; nevertheless, several aspects of care in the hospital or clinic can place patients at risk from infectious disease transmission. Paramount to the prevention of disease is the strict adherence to universal precautions for all patie


Value of assessing cryptococcal antigen in bronchoalveolar lavage and sputum specimens from patients with AIDS.
Mt Sinai J Med. 1998 Oct-Nov;65(5-6):422-5. Unique Identifier : AIDSLINE MED/99060364
Bottone EJ; Sindone M; Caraballo V; Department of Medicine, Mount Sinai School of Medicine, New York,; NY 10029, USA.
Cryptococcus neoformans has become a significant opportunistic pathogen, accounting for 8-10% of infectious complications in patients with AIDS. When encapsulated yeast cells are observed in Giemsa-stained smears of bronchoalveolar washings (BAL), or induced sputum specimens, confirmation as C. neoformans is germane t


Atovaquone compared with dapsone for the prevention of Pneumocystis carinii pneumonia in patients with HIV infection who cannot tolerate trimethoprim, sulfonamides, or both. Community Program for Clinical Research on AIDS and the AIDS Clinical Trials Group.
N Engl J Med. 1998 Dec 24;339(26):1889-95. Unique Identifier : AIDSLINE MED/99067153
El-Sadr WM; Murphy RL; Yurik TM; Luskin-Hawk R; Cheung TW; Balfour HH Jr; Eng R; Hooton TM; Kerkering TM; Schutz M; van der Horst C; Hafner R; Harlem Hospital Center and Columbia University College of; Physicians and Surgeons, New York, NY 10037, USA.
BACKGROUND: Although trimethoprim-sulfamethoxazole is the drug of choice for the prevention of Pneumocystis carinii pneumonia, many patients cannot tolerate it and must switch to an alternative agent. METHODS: We conducted a multicenter, open-label, randomized trial comparing daily atovaquone (1500-mg suspension) with


The care of HIV-infected adults in the United States. HIV Cost and Services Utilization Study Consortium [see comments]
N Engl J Med. 1998 Dec 24;339(26):1897-904. Unique Identifier : AIDSLINE MED/99067155
Bozzette SA; Berry SH; Duan N; Frankel MR; Leibowitz AA; Lefkowitz D; Emmons CA; Senterfitt JW; Berk ML; Morton SC; Shapiro MF; RAND Health, Santa Monica, CA, USA.
BACKGROUND AND METHODS: In order to elucidate the medical care of patients with human immunodeficiency virus (HIV) infection in the United States , we randomly sampled HIV-infected adults receiving medical care in the contiguous United States at a facility other than military, prison, o


Caring for people with human immunodeficiency virus infection [editorial; comment]
N Engl J Med. 1998 Dec 24;339(26):1926-8. Unique Identifier : AIDSLINE MED/99067159
Steinbrook R
Screening for distal sensory peripheral neuropathy in HIV-infected persons in research and clinical settings.
Neurology. 1998 Dec;51(6):1678-81. Unique Identifier : AIDSLINE MED/99071164
Marra CM; Boutin P; Collier AC; Department of Neurology, University of Washington, Seattle, USA.
OBJECTIVE: To determine the accuracy of a screening examination for distal sensory peripheral neuropathy (DSPN) performed by nonphysician clinicians and to explore the associations between DSPN and clinical features in HIV-infected persons. METHODS: A case-control stu


A randomized trial of amitriptyline and mexiletine for painful neuropathy in HIV infection. AIDS Clinical Trial Group 242 Protocol Team.
Neurology. 1998 Dec;51(6):1682-8. Unique Identifier : AIDSLINE MED/99071165
Kieburtz K; Simpson D; Yiannoutsos C; Max MB; Hall CD; Ellis RJ; Marra CM; McKendall R; Singer E; Dal Pan GJ; Clifford DB; Tucker T; Cohen B; University of Rochester Medical Center, NY 14620, USA.
BACKGROUND: Painful sensory neuropathy is a common complication of HIV infection. Based on prior uncontrolled observations, we hypothesized that amitriptyline or mexiletine would improve the pain symptoms. METHOD: A randomized, double-blind, 10-week trial of 145 patients assigned equally to amitriptyline, mexiletine,


AIDS-associated nephropathy: 5-year retrospective morphologic analysis of 87 cases.
Pathol Res Pract. 1998;194(8):567-70. Unique Identifier : AIDSLINE MED/98452527
Soriano-Rosas J; Avila-Casado MC; Carrera-Gonzalez E; Chavez-Mercado L; Cruz-Ortiz H; Rojo J; Department of Pathology, Mexico City General Hospital, National; University of Mexico, Mexico.
Morphologic findings in the kidneys of 138 consecutive acquired immunodeficiency syndrome (AIDS) autopsies performed at the Mexico City General Hospital between 1986 and 1991 were studied. A total of 87 cases (63%) had renal disease, 62 cases presented glomerular alterations, and 80 cases showed tubulointerstitial dam


[Nephrotoxicity of ritonavir]
Presse Med. 1998 Nov 14;27(35):1801-3. Unique Identifier : AIDSLINE MED/99067686
Deray G; Bochet M; Katlama C; Bricaire F; Service de Nephrologie, Groupe hospitalier Pitie-Salpetriere,; Paris.
A RECOGNIZED COMPLICATION: Ritonavir is an antiprotease used in the treatment of HIV-positive patients. Among the known side effects, nephrotoxicity can be severe. We have observed acute renal failure in 8 patients. CIRCUMSTANCES: Renal failure occurs


[Observing in HIV infections]
Presse Med. 1998 Nov 14;27(35):1818-9. Unique Identifier : AIDSLINE MED/99067689
Vittecocq D
[Aspergillus fumigatus muscle abscess revealing invasive aspergillosis in a patient with AIDS (letter)]
Presse Med. 1998 Nov 21;27(36):1844. Unique Identifier : AIDSLINE MED/99073362
Vandenbos F; Roger PM; Mondain-Miton V; Burel F; Battaglione-Hofman V; Dellamonica P
Transgenic cattle produced by reverse-transcribed gene transfer in oocytes.
Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14028-33. Unique Identifier : AIDSLINE MED/99045631
Chan AW; Homan EJ; Ballou LU; Burns JC; Bremel RD; Endocrinology-Reproductive Physiology Program, University of; Wisconsin, 1675 Observatory Drive, Madison, WI 53706, USA.
A critical requirement for integration of retroviruses, other than HIV and possibly related lentiviruses, is the breakdown of the nuclear envelope during mitosis. Nuclear envelope breakdown occurs during mitotic M-phase, the envelope reforming immediately after cell division, thereby permitting the translocation of th


Structural basis for efficient phosphorylation of 3'-azidothymidine monophosphate by Escherichia coli thymidylate kinase.
Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14045-50. Unique Identifier : AIDSLINE PDB/5TMP
Lavie A; Ostermann N; Brundiers R; Goody RS; Reinstein J; Konrad M; Schlichting I; Department of Physical Biochemistry, Max Planck Institute for; Molecular Physiology, Rheinlanddamm 201, 44139 Dortmund, Germany.
The crystal structures of Escherichia coli thymidylate kinase (TmpK) in complex with P1-(5 -adenosyl)-P5-(5 -thymidyl)pentaphosphate and P1-(5 -adenosyl)P5-[5 -(3 -azido-3 -deoxythymidine)] pentaphosphate have been solved to 2.0-A and 2.2-A resolution, respectively. The overall structure of the bacterial TmpK is very


A pyrimidine-rich exonic splicing suppressor binds multiple RNA splicing factors and inhibits spliceosome assembly.
Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14088-93. Unique Identifier : AIDSLINE MED/99045642
Zheng ZM; Huynen M; Baker CC; Basic Research Laboratory, Division of Basic Sciences, National; Cancer Institute, National Institutes of Health, Building 41,; Room D305, Bethesda, MD 20892-5055, USA. zheng@dce41.nci.nih.gov
The bovine papillomavirus type 1 (BPV-1) exonic splicing suppressor (ESS) is juxtaposed immediately downstream of BPV-1 splicing enhancer 1 and negatively modulates selection of a suboptimal 3 splice site at nucleotide 3225. The present study demonstrates that this pyrimidine-rich ESS inhibits utilization of upstream


Presentation of peptide antigens by mouse CD1 requires endosomal localization and protein antigen processing.
Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14314-9. Unique Identifier : AIDSLINE MED/99045681
Tangri S; Brossay L; Burdin N; Lee DJ; Corr M; Kronenberg M; Division of Developmental Immunology, La Jolla Institute for; Allergy and Immunology, San Diego, CA 92121, USA.
Mouse CD1(mCD1) molecules have been reported to present two types of antigens: peptides or proteins and the glycolipid alpha-galactosylceramide. Here, we demonstrate that a protein antigen, chicken ovalbumin (Ova), must be processed to generate peptides presented by mCD1 to CD8(+) T cells. The processing and mCD1-medi


Inhibition of intrathymic T cell development by expression of a transgenic antagonist peptide.
Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14349-54. Unique Identifier : AIDSLINE MED/99045687
Levelt CN; Mizoguchi E; Huang X; Zacks R; Bhan AK; Tonegawa S; Center for Cancer Research, Massachusetts Institute of; Technology, Cambridge, MA 02139, USA. clevelt@wccf.mit.edu
The mature T cell receptor (TCR) repertoire is shaped by positive- and negative-selection events taking place during T cell development. These events are regulated by interactions between the TCR and major histocompatibility complex molecules presenting self-peptides. It has been shown that many antagonist peptides ar


HIV type-1 infection of the cotton rat (Sigmodon fulviventer and S. hispidus).
Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14355-60. Unique Identifier : AIDSLINE MED/99045688
Langley RJ; Prince GA; Ginsberg HS; Virion Systems, Inc., 9610 Medical Center Drive, Rockville, MD; 20850, USA.
Cotton rats (Sigmodon hispidus and S. fulviventer) are susceptible to many viruses that infect humans (e.g., poliovirus, respiratory syncytial virus, influenza virus, adenovirus, and parainfluenza virus) and have been influential in developing therapeutic clinical intervention strategies for many viral infections of m


The neutral glycosphingolipid globotriaosylceramide promotes fusion mediated by a CD4-dependent CXCR4-utilizing HIV type 1 envelope glycoprotein.
Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14435-40. Unique Identifier : AIDSLINE MED/99045702
Puri A; Hug P; Jernigan K; Barchi J; Kim HY; Hamilton J; Wiels J; Murray GJ; Brady RO; Blumenthal R; Section of Membrane Structure and Function, Laboratory of; Experimental and Computational Biology, Division of Basic; Sciences, National Cancer Institute, National Institutes of; Health, Frederick, MD 21702, USA.
Previously, we showed that the addition of human erythrocyte glycosphingolipids (GSLs) to nonhuman CD4(+) or GSL-depleted human CD4(+) cells rendered those cells susceptible to HIV-1 envelope glycoprotein-mediated cell fusion. Individual components in the GSL mixture were isolated by fractionation on a silica-gel colu


Stochastic processes strongly influence HIV-1 evolution during suboptimal protease-inhibitor therapy.
Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14441-6. Unique Identifier : AIDSLINE +
Nijhuis M; Boucher CA; Schipper P; Leitner T; Schuurman R; Albert J; Eijkman-Winkler Institute, Department of Virology, University; Hospital Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The; Netherlands.
It has long been assumed that HIV-1 evolution is best described by deterministic evolutionary models because of the large population size. Recently, however, it was suggested that the effective population size (Ne) may be rather small, thereby allowing chance to influence evolution, a situation best described by a sto


Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity.
Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14500-5. Unique Identifier : AIDSLINE MED/99045713
Meucci O; Fatatis A; Simen AA; Bushell TJ; Gray PW; Miller RJ; Department of Pharmacological and Physiological Sciences,; University of Chicago, 947 E. 58th Street (MC 0926), Chicago, IL; 60637, USA.
The HIV-1 envelope protein gp120 induces apoptosis in hippocampal neurons. Because chemokine receptors act as cellular receptors for HIV-1, we examined rat hippocampal neurons for the presence of functional chemokine receptors. Fura-2-based Ca imaging showed that numerous chemokines, including SDF-1alpha, RANTES, and


The olfactory loss that accompanies an HIV infection.
Physiol Behav. 1998 Jun 15;64(4):549-56. Unique Identifier : AIDSLINE MED/98432375
Hornung DE; Kurtz DB; Bradshaw CB; Seipel DM; Kent PF; Blair DC; Emko P; Smell and Taste Disorders Clinic, SUNY HSC, Syracuse, NY 13210,; USA. hornung@vm.stlawu.edu
A number of studies have shown that HIV infection is associated with decreased olfactory ability. Additionally, it has been hypothesized that a reduced odorant identification may precede the advent of AIDS Dementia Complex (ADC). However, it is not known whether changes in olfactory ability are a manifestation of neur


[Coping--status of knowledge in the 90's]
Psychother Psychosom Med Psychol. 1998 Sep-Oct;48(9-10):321-37. Unique Identifier : AIDSLINE MED/99002142
Heim E
After a brief historical introduction the literature that has appeared on coping since the middle eighties is reviewed. Theoretically Lazarus concept of transactional coping has been developed with focus on emotions. Antonovsky s salutogenesis is considered to be innovative. Methodology is discussed in view of instru


Tuberculosis among foreign-born residents of southern Florida, 1995.
Public Health Rep. 1998 Nov-Dec;113(6):552-6. Unique Identifier : AIDSLINE MED/99064394
Granich RM; Zuber PL; McMillan M; Cobb JD; Burr J; Sfakianaki ED; Fussell M; Binkin NJ; School of Public Health, UC Berkeley, CA 94720, USA. rhg6@cdc.gov
OBJECTIVE: To examine the characteristics of foreign-born people with tuberculosis (TB) in Southern Florida, their contribution to the total number of TB cases, and available data on their HIV status as well as to determine the number of cases detected by the overseas medical screening of immigrants and refugees. METH


[Pseudomonas aeruginosa as a pathogen in patients with human immunodeficiency virus infection]
Rev Clin Esp. 1998 Sep;198 Suppl 2:37-43. Unique Identifier : AIDSLINE MED/99060467
Vidal Marsal F; Mensa Pueyo J; Hospital Universitario de Tarragona Joan XXIII, Departamento de; Medicina y Cirugia, Universidad Rovira i Virgili.
Transplacental transmission of hepatitis C virus in HIV-negative mothers.
Res Virol. 1998 Jul-Aug;149(4):229-34. Unique Identifier : AIDSLINE MED/98456677
Agha S; Sherif LS; Allam MA; Fawzy M; Clinical Pathology Department, Mansoura Faculty of Medicine,; Mansoura University, Egypt.
The aim of this work was to evaluate transplacental transmission of hepatitis C virus (HCV) in HIV-negative pregnant women who were HCV-PCR-positive, and also to determine the serotypes of the virus in these cases. Therefore, 767 pregnant women were screened for anti-HCV antibodies, hepatitis B surface antigen (HBsAg)


[Strategies for the use of anti-retroviral agents in HIV infection (1997). Extracts from the 4th Dormont Report]
Rev Pneumol Clin. 1998 Feb;54(1):9-16. Unique Identifier : AIDSLINE MED/98442115
[Lung diseases in HIV-infected children]
Schweiz Med Wochenschr. 1998 Sep 12;128(37):1375-84. Unique Identifier : AIDSLINE MED/98456700
Nadal D; Universitats-Kinderklinik Zurich.
Pulmonary diseases, including opportunistic and bacterial infections, lymphoproliferative disorders, and neoplasia, substantially contribute to morbidity and mortality in HIV-infected children. Current treatment modalities are largely successful and thus justify invasive aetiological diagnostic procedures.


On World AIDS Day, a shadow looms over southern Africa [news]
Science. 1998 Dec 4;282(5395):1790-1. Unique Identifier : AIDSLINE MED/99084272
Balter M
Kick-starting the AIDS vaccine effort [news]
Science. 1998 Dec 4;282(5395):1791. Unique Identifier : AIDSLINE MED/99084273
Balter M
AIDS research. New czar aims to sharpen France's effort [news]
Science. 1998 Dec 4;282(5395):1799. Unique Identifier : AIDSLINE MED/99084277
Balter M
The enigmas of Kaposi's sarcoma.
Science. 1998 Dec 4;282(5395):1837-9. Unique Identifier : AIDSLINE MED/99084284
Gallo RC; Institute of Human Virology, University of Maryland, Baltimore,; MD 21201, USA. coleman@umbi.umd.edu
Genetic acceleration of AIDS progression by a promoter variant of CCR5.
Science. 1998 Dec 4;282(5395):1907-11. Unique Identifier : AIDSLINE MED/99055403
Martin MP; Dean M; Smith MW; Winkler C; Gerrard B; Michael NL; Lee B; Doms RW; Margolick J; Buchbinder S; Goedert JJ; O'Brien TR; Hilgartner MW; Vlahov D; O'Brien SJ; Carrington M; Science Applications International Corporation (SAIC), National; Cancer Institute, Frederick MD 21702, USA.
The CCR5 gene encodes a cell surface chemokine receptor molecule that serves as the principal coreceptor, with CD4, for macrophage-tropic (R5) strains of human immunodeficiency virus-type 1 (HIV-1). Genetic association analysis of five cohorts of people with acquired immunodeficiency syndrome (AIDS) revealed that infe


Defective T cell differentiation in the absence of Jnk1.
Science. 1998 Dec 11;282(5396):2092-5. Unique Identifier : AIDSLINE MED/99069629
Dong C; Yang DD; Wysk M; Whitmarsh AJ; Davis RJ; Flavell RA; Section of Immunobiology, Howard Hughes Medical Institute, Yale; University School of Medicine, New Haven, CT 06520, USA.
The c-Jun NH2-terminal kinase (JNK) signaling pathway has been implicated in the immune response that is mediated by the activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. JNK activity observed in wild-type activated TH cells was severely reduced in TH cells from Jnk1-/- mice. T


Psychological distress in blood donors notified of HTLV-I/II infection. Retrovirus Epidemiology Donor Study.
Transfusion. 1998 Nov-Dec;38(11-12):1056-62. Unique Identifier : AIDSLINE MED/99056317
Guiltinan AM; Murphy EL; Horton JA; Nass CC; McEntire RL; Watanabe K; Blood Centers of the Pacific, San Francisco, California.
BACKGROUND: Blood donations in the United States have been screened for antibody to human T-cell lymphotropic virus types I and II (HTLV-I/II) since November 1988. Although clinically diagnosed illness associated with HTLV-I/II remains relatively uncommon, blood donors notified of HTLV


Low prevalence of human T-cell lymphotropic virus type I infection among volunteer blood donors in Taiwan [letter]
Transfusion. 1998 Nov-Dec;38(11-12):1118-9. Unique Identifier : AIDSLINE MED/99056325
Chang CS; Wu YW; Pan YC; Chen ZY; Hsu A; Wang CS
Effect of major histocompatibility complex expression on murine intestinal graft survival.
Transplantation. 1998 Nov 27;66(10):1369-74. Unique Identifier : AIDSLINE MED/99060958
Cagiannos C; Zhong R; Zang Z; Jiang J; Garcia BM; Chakrabarti S; Jevnikar AM; Sinclair NR; Grant DR; Department of Surgery, London Health Sciences Centre, Ontario,; Canada.
BACKGROUND: Clinical intestinal transplantation has been plagued by frequent and severe graft rejection. It has been proposed that the major histocompatibility complex (MHC) antigens might play a critical role in this process owing to their extensive expression on enterocytes and mucosa-associated immune cells. METHOD


Long-term nonprogressive human immunodeficiency virus-1 infection in a kidney allograft recipient.
Transplantation. 1998 Nov 27;66(10):1384-6. Unique Identifier : AIDSLINE MED/99060960
Purgus R; Tamalet C; Poignard P; Spire B; George F; Robert A; Olmer M; Department of Nephrology, Hopital Conception, Marseille, France.
We report a unique case of a renal transplant patient with a long-term nonprogressive human immunodeficiency virus type-1 (HIV-1) infection and who is asymptomatic despite sustained immunosuppression. Renal function is normal, and HIV infection was probably acquired through blood transfusion before the transplant. Non


CD8+ T lymphocytes account for acute accelerated allograft rejection in the rag mouse model.
Transplant Proc. 1998 Nov;30(7):2952. Unique Identifier : AIDSLINE MED/99055680
Yoshimura R; Wada S; Nakatani T; Tsujino T; Yamamoto K; Kishimoto T; Ohyama A; Chargui J; Touraine JL; Department of Urology, Osaka City University Hospital, Japan.
Correlation between biopsies and noninvasive assessment of acute graft dysfunction.
Transplant Proc. 1998 Nov;30(7):3069. Unique Identifier : AIDSLINE MED/99055731
Akhtar F; Rana TA; Kazi J; Zafar N; Hashmi A; Bhatti S; Naqvi R; Mohsin R; Naqvi A; Rizvi A; Sindh Institute of Urology and Transplantation (SIUT), Dow; Medical College, Karachi, Pakistan.
Kaposi sarcoma-associated herpesvirus/human herpesvirus type 8 and Epstein-Barr virus in immunosuppressed renal transplant recipients.
Transplant Proc. 1998 Nov;30(7):3166-7. Unique Identifier : AIDSLINE MED/99055779
Demirag A; Hizel N; Karakayali H; Moray G; Akkoc H; Bilgin N; Haberal M; Department of General Surgery, Faculty of Medicine, Baskent; University, Ankara, Turkey.
Long-term results in human T-cell leukemia virus type 1-positive renal transplant recipients.
Transplant Proc. 1998 Nov;30(7):3168-70. Unique Identifier : AIDSLINE MED/99055780
Tanabe K; Kitani R; Takahashi K; Tokumoto T; Ishikawa N; Oshima T; Kanematsu A; Fuchinoue S; Yagisawa T; Ota K; Toma H; Department of Urology, Kidney Center, Tokyo Women's Medical; College, Japan.
Differences in cellular mechanisms between heart and skin graft rejection by in vitro and in vivo analyses.
Transplant Proc. 1998 Nov;30(7):3854. Unique Identifier : AIDSLINE MED/99056065
Yamamoto T; Yamaguchi J; Gu W; Ishii T; Hashimoto T; Usui K; Mizoe A; Azuma T; Fujioka H; Furui J; Kanematsu T; Department of Surgery II, Nagasaki University School of Medicine,; Japan.
Second-set rejection of skin allografts mediated by a T-cell subset in a chimeric mouse model.
Transplant Proc. 1998 Nov;30(7):3858-9. Unique Identifier : AIDSLINE MED/99056067
Yoshimura R; Wada S; Nakatani T; Tsujino T; Yamamoto K; Kishimoto T; Ohyama A; Chargui J; Touraine JL; Department of Urology, Osaka City University Hospital, Japan.
Anti-alpha beta-T cell receptor monoclonal antibody induces tolerance without dominant infiltration by Th2 cells into grafts.
Transplant Proc. 1998 Nov;30(7):3892. Unique Identifier : AIDSLINE MED/99056082
Hamano K; Ito H; Shirasawa B; Bashuda H; Gohra H; Katoh T; Fujimura Y; Esato K; First Department of Surgery, Yamaguchi University School of; Medicine, Japan.
The Warthin-Finkeldey-type giant cell in HIV infection, what is it?
Ultrastruct Pathol. 1998 Jul-Aug;22(4):293-303. Unique Identifier : AIDSLINE MED/99022170
Orenstein JM; Department of Pathology, George Washington University,; Washington, DC, USA. patjmo@gwumc.edu
A study was conducted to ascertain the origin of the Warthin-Finkeldey-type giant cell that is common to lymphoid tissues of HIV-infected individuals. Light microscopy (LM) and transmission electron microscopy (TEM), in situ hybridization (ISH) (HIV-specific RNA), and immunohistochemistry (HIV p24, OPD4, CD3, CD45 UCH


HIV infection and signal transduction.
J Biol Regul Homeost Agents. 1998 Jul-Sep;12(3):63-6. Unique Identifier : AIDSLINE MED/99011925
Bovolenta C; Camorali L; Lorini AL; Poli G; AIDS Immunophatogenesis Unit, DIBIT, San Raffaele Scientific; Institute, Milano, Italy. bovolenta.chiara@hsr.it
Patient acceptance and shortened cycles paint optimistic future for therapeutic vaccine manufacturers [news]
Allergol Immunopathol (Madr). 1998 Jul-Aug;26(4):201. Unique Identifier : AIDSLINE MED/99033198
Detecting disseminated Mycobacterium avium complex infections in HIV-positive patients. The usefulness of bone marrow trephine biopsy specimens, aspirate cultures, and blood cultures.
Am J Clin Pathol. 1998 Dec;110(6):806-9. Unique Identifier : AIDSLINE MED/99060584
Hussong J; Peterson LR; Warren JR; Peterson LC; Department of Pathology, Northwestern University Medical School,; Chicago, Illinois, USA.
Disseminated Mycobacterium avium complex (MAC) infections are common in patients with acquired immunodeficiency syndrome (AIDS). These patients frequently seek care with fever accompanied by generalized systemic symptoms and undergo bone marrow biopsy. It is our practice to stain all bone marrow trephine biopsy specim


Correlates of HIV seropositivity and HIV testing among out-of-treatment drug users.
Am J Drug Alcohol Abuse. 1998 Aug;24(3):377-93. Unique Identifier : AIDSLINE MED/98412972
Collier K; Kotranski L; Semaan S; Lauby J; Halbert J; Feighan K; Philadelphia Health Management Corporation, Pennsylvania, USA.
This study: 1) examined the rate and correlates of human immunodeficiency virus (HIV) seropositivity; and 2) assessed whether self-selection in HIV testing influenced the rate and correlates of HIV seropositivity in a group of out-of-treatment drug users. Data were collected from 856 out-of-treatment drug users in Phi


Drug abuse treatment and risky sex: evidence for a cumulative treatment effect?
Am J Drug Alcohol Abuse. 1998 Aug;24(3):439-51. Unique Identifier : AIDSLINE MED/98412976
Longshore D; Hsieh S; UCLA Drug Abuse Research Center, Los Angeles, California 90024,; USA.
This paper presents evidence regarding the possibility of a cumulative effect of drug-abuse treatment on reducing risky sexual behavior among individuals entering drug-abuse treatment in the United States from 1991-1993 and participating in the Drug Abuse Treatment Outcome Study (DATOS


Discontinuing anticytomegalovirus therapy in patients with immune reconstitution after combination antiretroviral therapy.
Am J Ophthalmol. 1998 Dec;126(6):817-22. Unique Identifier : AIDSLINE MED/99075349
Jabs DA; Bolton SG; Dunn JP; Palestine AG; Department of Ophthalmology, The Johns Hopkins University School; of Medicine, Baltimore, Maryland, USA.; dajabs@welchlink.welch.jhu.edu
PURPOSE: To describe our experience with discontinuation of anticytomegalovirus maintenance therapy in patients who have had immune reconstitution after initiation of highly active antiretroviral therapy. METHODS: Fifteen patients with treated cytomegalovirus retinitis, who had immune reconstitution after initiation o


Epibulbar allergic granulomatous nodules in a human immunodeficiency virus-positive patient.
Am J Ophthalmol. 1998 Dec;126(6):844-6. Unique Identifier : AIDSLINE MED/99075361
Godfrey DG; Carr JD; Grossniklaus HE; Department of Ophthalmology, Emory University School of Medicine,; Atlanta, Georgia, USA.
PURPOSE: To report an unusual epibulbar inflammatory process in a patient with human immunodeficiency virus (HIV). METHODS: Case report. A 32-year-old man developed fleshy epibulbar nodules on his right conjunctiva and cornea after being treated for conjunctivitis. A biopsy of the lesions was done, and the specimen wa


T-cell-rich large-B-cell lymphomas contain non-activated CD8+ cytolytic T cells, show increased tumor cell apoptosis, and have lower Bcl-2 expression than diffuse large-B-cell lymphomas.
Am J Pathol. 1998 Dec;153(6):1707-15. Unique Identifier : AIDSLINE MED/99061418
Felgar RE; Steward KR; Cousar JB; Macon WR; Department of Pathology, Vanderbilt University Medical Center,; Nashville, Tennessee, USA. raymond.felgar@gte.net
The factor(s) responsible for the reduced B cell number and increased T cell infiltrate in T-cell-rich large-B-cell lymphomas (TCRBCLs) have not been well characterized. We studied 18 TCRBCLs and 12 diffuse large-B-cell lymphomas (DLBCLs) to compare the 1) predominant T cell subpopulation(s), 2) expression of cytotoxi


T cell apoptosis in human heart allografts: association with lack of co-stimulation?
Am J Pathol. 1998 Dec;153(6):1813-24. Unique Identifier : AIDSLINE MED/99061429
Van Hoffen E; Van Wichen DF; Leemans JC; Broekhuizen RA; Bruggink AH; De Boer M; De Jonge N; Kirkels H; Slootweg PJ; Gmelig-Meyling FH; De Weger RA; Department of Pathology, University Hospital, Utrecht, The; Netherlands.
It is unclear whether the intracardial immune reactivity after heart transplantation influences the peripheral immunological status (activation or nonresponsiveness) of the patient. Co-stimulation and activation-induced cell death (AICD) or apoptosis play an important role in determining the balance between lymphocyte


Herpes virus type 8-negative primary effusion lymphoma associated with PAX-5 gene rearrangement and hepatitis C virus: a case report and review of the literature.
Am J Surg Pathol. 1998 Dec;22(12):1528-37. Unique Identifier : AIDSLINE MED/99065431
Ichinohasama R; Miura I; Kobayashi N; Saitoh Y; DeCoteau JF; Saiki Y; Mori S; Kadin ME; Ooya K; Department of Oral Pathology, Tohoku University School of; Dentistry, Sendai, Japan. ryo@mail.cc.tohoku.ac.jp
At present, there is no case report of HHV8- primary effusion lymphoma (PEL) with t(9;14)(p13;q32) involving both PAX-5 and immunoglobulin heavy chain gene rearrangement, which is a rare translocation in B-cell non-Hodgkin s lymphoma , in an HIV- patient. We examined an HIV-seronega


In situ RT-PCR detection of Epstein-Barr virus immediate-early transcripts in CD4+ and CD8+ T lymphocytes.
Anticancer Res. 1998 Sep-Oct;18(5A):3171-80. Unique Identifier : AIDSLINE MED/99075977
Guan M; Romano G; Henderson EE; Department of Microbiology and Immunology, Temple University; School of Medicine, Philadelphia, Pennsylvania 19140, USA.
AIDS-related Epstein-Barr virus (EBV)-associated T cell lymphomas are emerging as a new, distinct histopathological entity. The pathway whereby EBV infects T cells as well as the initial EBV transcriptional program in T cells has not been established. In order to shed light on the early events of the EBV infection of


Intracellular association of FGF-2 with the ribosomal protein L6/TAXREB107.
Biochem Biophys Res Commun. 1998 Nov 18;252(2):524-8. Unique Identifier : AIDSLINE MED/99045440
Shen B; Arese M; Gualandris A; Rifkin DB; Department of Cell Biology, Kaplan Cancer Center, and the Raymond; and Beverly Sackler Foundation Laboratory, New York University; Medical Center, New York, New York, 10016, USA.; shenb01@mcrcr6.med.nyu.edu
By using the yeast two-hybrid system, we identified the ribosomal protein L6/TAXREB107 as an intracellular partner for FGF-2. L6/TAXREB107 also mediates the DNA binding of the HTLV-1 transactivator Tax. In vitro binding experiments indicated that both the high-molecular-weight forms (HMW) and the 18-kDa form of FGF-2


Neurovirulent simian immunodeficiency virus induces calbindin-D-28K in astrocytes.
Mol Chem Neuropathol. 1998 May;34(1):25-38. Unique Identifier : AIDSLINE MED/98451666
Berman NE; Yong C; Raghavan R; Raymond LA; Joag SV; Narayan O; Cheney PD; Department of Anatomy and Cell Biology, University of Kansas; Medical Center, Kansas City 66160-7400, USA.
Astrocyte activation has been postulated to be a major contributor to functional changes in the brain of AIDS patients. We assessed astrocyte activation in the simian immunodeficiency virus (SIV) model. Four groups of macaque brains were examined: uninoculated controls, animals inoculated with virus that did not cause


Magnetoliposomes may be useful for elimination of HIV from infected individuals.
Z Naturforsch [C]. 1998 Sep-Oct;53(9-10):935-6. Unique Identifier : AIDSLINE MED/99042988
Babincova M; Machova E; Department of Biophysics and Chemical Physics, Comenius; University, Bratislava, Slovakia. babincova@fmph.uniba.sk
A simple method is proposed for the treatment of the acquired immunodeficiency syndrome (AIDS) by introducing into the blood stream magnetoliposomes with coupled human immunodeficiency virus (HIV) receptor proteins. After some time lag, needed for binding of HIV and HIV-infected cells to magnetoliposomes, the arterio-


[FDA approval of the first HIV anti-retroviral from DuPont-Pharma: SUSTIVA (efavirenz). SUSTIVA should be associated with other anti-retrovirals and could be considered a new alternative first line treatment]
Allerg Immunol (Paris). 1998 Oct;30(8):268-70. Unique Identifier : AIDSLINE MED/99062627
Increase in plasma viral load after oral cholera immunization of HIV-infected subjects.
AIDS. 1998 Oct 1;12(14):F145-50. Unique Identifier : AIDSLINE MED/99006856
Ortigao-de-Sampaio MB; Shattock RJ; Hayes P; Griffin GE; Linhares-de-Carvalho MI; Ponce de Leon A; Lewis DJ; Castello-Branco LR; Departamento de Imunologia, IOC, FIOCRUZ, Rio de Janeiro, Brazil.
OBJECTIVE: Constant antigenic stimulation of the large immune cell population contained within gut-associated lymphoid tissue during HIV infection may contribute to patients total viral load. The aim of this investigation was to evaluate the effect of a mucosal antigenic challenge on HIV replication. DESIGN: Prospect


A randomized double-blind trial of the addition of lamivudine or matching placebo to current nucleoside analogue reverse transcriptase inhibitor therapy in HIV-infected children: the PENTA-4 trial. Paediatric European Network for Treatment of AIDS.
AIDS. 1998 Oct 1;12(14):F151-60. Unique Identifier : AIDSLINE MED/99006857
OBJECTIVES: To evaluate the toxicity, tolerability and effect on laboratory markers of adding lamivudine ( 3TC ) to nucleoside analogue reverse transcriptase inhibitors (NRTI) in children with HIV-1 infection. DESIGN: Randomized double-blind trial. METH


Stable rearrangements of the beta3-beta4 hairpin loop of HIV-1
Unique Identifier : AIDSLINE MED/99006858
Adverse effects of reverse transcriptase inhibitors: mitochondrial toxicity as common pathway [editorial]
AIDS. 1998 Oct 1;12(14):1735-44. Unique Identifier : AIDSLINE MED/99006859
Brinkman K; ter Hofstede HJ; Burger DM; Smeitink JA; Koopmans PP; Department of General Internal Medicine, University Hospital; Nijmegen, The Netherlands.
Low T-cell responses to CD3 plus CD28 monoclonal antibodies are predictive of development of AIDS.
AIDS. 1998 Oct 1;12(14):1745-51. Unique Identifier : AIDSLINE MED/99006860
Roos MT; Prins M; Koot M; de Wolf F; Bakker M; Coutinho RA; Miedema F; Schellekens PT; Department of Clinical Viro-Immunology, Central Laboratory of the; Netherlands Red Cross Blood Transfusion Service, Academic Medical; Centre, University of Amsterdam.
OBJECTIVE: Decreased T-cell reactivity in vitro is strongly associated with progression to AIDS and low CD4+ T-cell numbers. Low T-cell responses in vitro induced by CD3 monoclonal antibody (mAb) are predictive for progression to AIDS independent of low CD4+ T-cell counts and high HIV-1 RNA levels. We developed a whol


Purified Tat induces inflammatory response genes in Kaposi's sarcoma cells.
AIDS. 1998 Oct 1;12(14):1753-61. Unique Identifier : AIDSLINE MED/99006861
Kelly GD; Ensoli B; Gunthel CJ; Offermann MK; Winship Cancer Center, Department of Medicine, Emory University,; Atlanta, Georgia 30322, USA.
OBJECTIVE: Kaposi s sarcoma (KS) is a neoplasm strongly associated with HIV-1 infection and marked by leukocytic infiltration. The infiltrating leukocytes are a possible source of inflammatory cytokines, human herpesvirus 8 (HHV8) and the HIV-1 transactivator protein Tat. This study examines whether Tat directly induc


Persistent T cell and B cell activities in the duodenal mucosa of AIDS patients.
AIDS. 1998 Oct 1;12(14):1763-9. Unique Identifier : AIDSLINE MED/99006862
Carol M; Lambrechts A; Urbain D; van Vooren JP; Clumeck N; Goldman M; Mascart-Lemone F; Department of Immunology, Hopital Erasme, Bruxelles, Belgium.
OBJECTIVE: As HIV infection most commonly occurs via a mucosal surface, and as gastrointestinal symptoms are very frequent among HIV-infected patients, we investigated the functional properties of residual lymphocytes in the duodenal mucosa from HIV-infected individuals. DESIGN: Duodenal biopsies and blood samples wer


Persistence of Pseudomonas aeruginosa strains in respiratory infection in AIDS patients.
AIDS. 1998 Oct 1;12(14):1771-5. Unique Identifier : AIDSLINE MED/99006863
Asboe D; Gant V; Aucken HM; Moore DA; Umasankar S; Bingham JS; Kaufmann ME; Pitt TL; Department of Genitourinary/HIV Medicine, St Thomas' Hospital,; London, UK.
OBJECTIVES: To establish the clinical pattern of Pseudomonas aeruginosa respiratory infections in HIV-seropositive patients and to determine whether repeated isolation of the organism represents reinfection or recurrence and to assess whether common source, nosocomial infection occurred. DESIGN AND METHODS: Evaluation


Effect of indinavir on HIV-related wasting.
AIDS. 1998 Oct 1;12(14):1777-84. Unique Identifier : AIDSLINE MED/99006864
Carbonnel F; Maslo C; Beaugerie L; Carrat F; Wirbel E; Aussel C; Gobert JG; Girard PM; Gendre JP; Cosnes J; Rozenbaum W; Service de Gastroenterologie et de Nutrition, Hopital; Rothschild, Paris, France.
OBJECTIVE: To study the effect of the protease inhibitor indinavir on body weight and body composition of subjects with HIV-related wasting. DESIGN: Prospective measurement of body weight in patients who had wasting and were treated with indinavir. A subgroup of 16 representative patients also underwent a metabolic st


Serum immunoreactive erythropoietin levels and associated factors amongst HIV-infected children.
AIDS. 1998 Oct 1;12(14):1785-91. Unique Identifier : AIDSLINE MED/99006865
Allen UD; King SM; Gomez MP; Lapointe N; Forbes JC; Thorne A; Kirby MA; Bowker J; Raboud J; Singer J; Mukwaya G; Tobin J; Read SE; Canadian Pediatric AIDS Research Group.
OBJECTIVES: To determine the spectrum of serum immunoreactive erythropoietin (SIE) levels amongst HIV-infected children aged


Bacillary angiomatosis in immunocompromised patients.
AIDS. 1998 Oct 1;12(14):1793-803. Unique Identifier : AIDSLINE MED/99006866
Gasquet S; Maurin M; Brouqui P; Lepidi H; Raoult D; Unite des Rickettsies, CNRS UPRES A 6020, Universite de la; Mediterranee, Marseille, France.
OBJECTIVES: To report seven cases of bacillary angiomatosis ; to evaluate the most useful diagnostic tools; to analyse the clinical and epidemiological features associated with Bartonella quintana or Bartonella henselae infections. DESIGN: Clinical, diagnostic and epidemiologi


Safety of the maternal-infant zidovudine regimen utilized in the Pediatric AIDS Clinical Trial Group 076 Study.
AIDS. 1998 Oct 1;12(14):1805-13. Unique Identifier : AIDSLINE MED/99006867
Sperling RS; Shapiro DE; McSherry GD; Britto P; Cunningham BE; Culnane M; Coombs RW; Scott G; Van Dyke RB; Shearer WT; Jimenez E; Diaz C; Harrison DD; Delfraissy JF; Department of Obstetrics, Gynecology and Reproductive Science,; Mount Sinai School of Medicine, New York, New York, USA.
OBJECTIVE: To determine the safety of the zidovudine (ZDV) regimen utilized in the Pediatric AIDS Clinical Trial Group (ACTG) 076 study. DESIGN: ACTG 076 was a randomized, double-blind, placebo-controlled trial which demonstrated that a ZDV regimen could prevent mother-to-child HIV-1 transmission. Infants were followe


Opportunistic infections occurring during highly active antiretroviral treatment.
AIDS. 1998 Oct 1;12(14):1815-22. Unique Identifier : AIDSLINE MED/99006868
Michelet C; Arvieux C; Francois C; Besnier JM; Rogez JP; Breux JP; Souala F; Allavena C; Raffi F; Garre M; Cartier F; Infectious Disease Unit, Hopital Pontchaillou, University; hospital, Rennes, France.
OBJECTIVE: To analyse the characteristics of opportunistic infections in patients receiving highly active antiretroviral treatment (HAART). DESIGN AND METHODS: A retrospective study performed in seven hospitals, included all patients starting treatment by


CD4 cell count as a surrogate endpoint in HIV clinical trials: a meta-analysis of studies of the AIDS Clinical Trials Group.
AIDS. 1998 Oct 1;12(14):1823-32. Unique Identifier : AIDSLINE MED/99006869
Hughes MD; Daniels MJ; Fischl MA; Kim S; Schooley RT; Department of Biostatistics, and Center for Biostatistics in AIDS; Research, Harvard School of Public Health, Boston, Massachusetts; 02115, USA.
OBJECTIVE: To evaluate initial changes in CD4 cell count as a surrogate endpoint for clinical outcome in HIV-infected patients. DESIGN: Meta-analysis of all relevant Phase II and III randomized clinical trials undertaken by the Adult AIDS Clinical Trials Group. METHODS: Individual patient data were obtained from each


Immunologic effects of combined protease inhibitor and reverse transcriptase inhibitor therapy in previously treated chronic HIV-1 infection.
AIDS. 1998 Oct 1;12(14):1833-44. Unique Identifier : AIDSLINE MED/99006870
Giorgi JV; Majchrowicz MA; Johnson TD; Hultin P; Matud J; Detels R; Multicenter AIDS Cohort Study and University of California Los; Angeles School of Medicine, 90095-1745, USA.
OBJECTIVE: To evaluate the efficacy of combination protease and reverse transcriptase inhibitor therapy in correcting HIV-1-induced lymphocyte subset abnormalities in previously treated adults. DESIGN: A 48-week observational study of lymphocyte subsets in 12 participants in the Multicenter AIDS Cohort Study who were


Involvement of hormonal circadian secretion in the growth of HIV-infected children.
AIDS. 1998 Oct 1;12(14):1845-50. Unique Identifier : AIDSLINE MED/99006871
Rondanelli M; Caselli D; Maccabruni A; Maghnie M; Bacchella L; DeStefano A; Solerte SB; Minoli L; Ferrari E; Department of Internal Medicine and Medical Therapy, IRCCS San; Matteo Hospital, Pavia, Italy.
OBJECTIVE: To evaluate the circadian secretion of hormones involved in the regulation of growth in childhood, namely growth hormone, insulin-like growth factor (IGF)-I, cortisol, adrenocorticotropin hormone (ACTH), and thyroid-stimulating hormone (TSH) in HIV-infected children. DESIGN: The circadian secretory pattern


Protection against sexually transmitted diseases by granting sex workers in Thailand the choice of using the male or female condom: results from a randomized controlled trial.
AIDS. 1998 Oct 1;12(14):1851-9. Unique Identifier : AIDSLINE MED/99006872
Fontanet AL; Saba J; Chandelying V; Sakondhavat C; Bhiraleus P; Rugpao S; Chongsomchai C; Kiriwat O; Tovanabutra S; Dally L; Lange JM; Rojanapithayakorn W; Joint United Nations Programme on HIV/AIDS (UNAIDS), Geneva,; Switzerland.
BACKGROUND: The male condom is the most effective barrier method available for protection against sexually transmitted diseases (STDs), including HIV infection. There is an urgent need to develop and evaluate other prevention methods, such as the female condom. This study estimated the additional protection against ST


The relationship of HIV prevalence in pregnant women to that in women of reproductive age: a validated method for adjustment.
AIDS. 1998 Oct 1;12(14):1861-7. Unique Identifier : AIDSLINE MED/99006873
Nicoll A; Stephenson J; Griffioen A; Cliffe S; Rogers P; Boisson E; HIV and STD Division, Public Health Laboratory Service; Communicable Disease Surveillance Centre, London, UK.
OBJECTIVE: To devise and validate a method for adjusting HIV seroprevalences in pregnant women to estimate population prevalences among all women in their child-bearing years. DESIGN: Birth and termination rates from women with known HIV infection in the United Kingdom were calculated


HIV testing and counseling among men attending sexually transmitted disease clinics in Pune, India: changes in condom use and sexual behavior over time.
AIDS. 1998 Oct 1;12(14):1869-77. Unique Identifier : AIDSLINE MED/99006874
Bentley ME; Spratt K; Shepherd ME; Gangakhedkar RR; Thilikavathi S; Bollinger RC; Mehendale SM; Department of International Health, School of Hygiene and Public; Health, Johns Hopkins University, Baltimore, Maryland 21205, USA.
OBJECTIVES: To describe changes in sexual behavior and condom use among male heterosexual clients at two public sexually transmitted disease (STD) clinics in Pune, after exposure to HIV testing, counseling, and condom promotion. DESIGN: From 13 May 1993 to 11 April 1997, 6819 heterosexual men were screened for HIV inf


Migration, ethnicity and environment: HIV risk factors for women on the sugar cane plantations of the Dominican Republic.
AIDS. 1998 Oct 1;12(14):1879-87. Unique Identifier : AIDSLINE MED/99006875
Brewer TH; Hasbun J; Ryan CA; Hawes SE; Martinez S; Sanchez J; Butler de Lister M; Constanzo J; Lopez J; Holmes KK; AIDSCAP, Santo Domingo, Dominican Republic.
OBJECTIVE: To determine risk factors for HIV infection among women living in the sugar cane plantation communities (bateyes) of a large private sugar cane company in the Dominican Republic . DESIGN: Cross-sectional study of sexually


HIV-1 seroconversion in a prospective study of female sex workers in northern Thailand: continued high incidence among brothel-based women.
AIDS. 1998 Oct 1;12(14):1889-98. Unique Identifier : AIDSLINE MED/99006876
Kilmarx PH; Limpakarnjanarat K; Mastro TD; Saisorn S; Kaewkungwal J; Korattana S; Uthaivoravit W; Young NL; Weniger BG; St Louis ME; The HIV/AIDS Collaboration, Nonthaburi, Thailand.
OBJECTIVES: To determine the incidence of HIV-1 infection, temporal trends in incidence, and risk factors for seroconversion in a cohort of female commercial sex workers (CSW) in upper northern Thailand , the region of Thailand with the highest rates of HIV-1 infection. METHODS: C


Decline in sexually transmitted disease prevalence in female Bolivian sex workers: impact of an HIV prevention project.
Unique Identifier : AIDSLINE MED/99006877
Levine WC; Revollo R; Kaune V; Vega J; Tinajeros F; Garnica M; Estenssoro M; Lewis JS; Higueras G; Zurita R; Wright-De Aguero L; Pareja R; Miranda P
HIV-1 genetic subtype A/B recombinant strain causing an explosive epidemic in injecting drug users in Kaliningrad.
AIDS. 1998 Oct 1;12(14):1907-19. Unique Identifier : AIDSLINE MED/99006878
Liitsola K; Tashkinova I; Laukkanen T; Korovina G; Smolskaja T; Momot O; Mashkilleyson N; Chaplinskas S; Brummer-Korvenkontio H; Vanhatalo J; Leinikki P; Salminen MO; Department of Infectious Disease Epidemiology, National Public; Health Institute, Helsinki, Finland.
OBJECTIVES: To investigate the molecular epidemiology and genetic structure of the virus strain(s) causing an outbreak of HIV-1 infection in the Kaliningrad province of the Russian Federation and to investigate the relationship of this outbreak to some other emerging HIV-1 epidemics in the countries of the former Sovi


Increasing Kaposi's sarcoma-associated herpesvirus seroprevalence with age in a highly Kaposi's sarcoma endemic region, Zambia in 1985.
AIDS. 1998 Oct 1;12(14):1921-5. Unique Identifier : AIDSLINE MED/99006879
Olsen SJ; Chang Y; Moore PS; Biggar RJ; Melbye M; Division of Epidemiology, Columbia University, New York, New York; 10032, USA.
BACKGROUND: Kaposi s sarcoma (KS)-associated herpesvirus (KSHV) is a newly discovered virus found in all forms of KS. In the United States , KSHV infection appears to be most common amongst individuals at high-risk for KS. Preliminary data from Africa suggest that KSHV infection may be


HTLV-I infection in Spain. HTLV Spanish Study Group [letter]
AIDS. 1998 Oct 1;12(14):1927-8. Unique Identifier : AIDSLINE MED/99006880
Machuca A; Gutierrez M; Soriano V
Molecular analysis of HIV-1 relatedness in a case of viral transmission during a bloody fight between two adults [letter]
AIDS. 1998 Oct 1;12(14):1928-30. Unique Identifier : AIDSLINE GENBANK/AF023512
Brambilla A; Salvatori F; Pristera R; Alfano M; Vicenzi E
HIV suppression and risk of drug resistance mutations [letter]
AIDS. 1998 Oct 1;12(14):1930. Unique Identifier : AIDSLINE MED/99006882
Phillips AN; Loveday C; Johnson MA
Transient foscarnet-induced hypercalcaemia [letter]
AIDS. 1998 Oct 1;12(14):1930-1. Unique Identifier : AIDSLINE MED/99006883
Barba R; Gomez-Rodrigo J; Marco J; Espejo M; Mena D
Decline in the rate of specific opportunistic infections at San Francisco General Hospital, 1994-1997 [letter]
AIDS. 1998 Oct 1;12(14):1931-3. Unique Identifier : AIDSLINE MED/99006884
Holtzer CD; Jacobson MA; Hadley WK; Huang L; Stanley HD; Montanti R; Wong MK; Stansell JD
Poverty and prognosis of HIV infection in Switzerland. Swiss HIV Cohort Study [letter]
AIDS. 1998 Oct 1;12(14):1933-4. Unique Identifier : AIDSLINE MED/99006885
Ledergerber B; Egger M; Rickenbach M; Weber R
Delayed HIV-1 seroconversion after antiretroviral therapy [letter]
AIDS. 1998 Oct 1;12(14):1935-6. Unique Identifier : AIDSLINE MED/99006886
Apetrei C; Tamalet C; Edlinger C; Damond F; Descamps D; Saimot AG; Brun-Vezinet F; Simon F
Acute non-lymphoblastic leukemia with an unusual chromosomal abnormality in a patient with advanced AIDS [letter]
AIDS. 1998 Oct 1;12(14):1936-7. Unique Identifier : AIDSLINE MED/99006887
Mangialardi WJ; Raffanti SP
Disease progression and poor survival of AIDS-associated progressive multifocal leukoencephalopathy despite highly active antiretroviral therapy [letter]
AIDS. 1998 Oct 1;12(14):1937-8. Unique Identifier : AIDSLINE MED/99006888
De Luca A; Ammassari A; Cingolani A; Giancola ML; Antinori A
Acute clinical hepatitis in an HIV-seropositive hepatitis B carrier receiving protease inhibitor therapy [letter]
AIDS. 1998 Oct 1;12(14):1939-40. Unique Identifier : AIDSLINE MED/99006889
Mastroianni CM; Trinchieri V; Santopadre P; Lichtner M; Forcina G; D'Agostino C; Corpolongo A; Vullo V
Tribute to Jonathan Mann.
AIDS. 1998 Oct 22;12(15):ii-v. Unique Identifier : AIDSLINE MED/99030022
Ryder RW; Paul JR; Yale University School of Public Health, New Haven, Connecticut,; USA.
Treatment with protease inhibitors associated with peripheral insulin resistance and impaired oral glucose tolerance in HIV-1-infected patients.
AIDS. 1998 Oct 22;12(15):F167-73. Unique Identifier : AIDSLINE MED/99030023
Walli R; Herfort O; Michl GM; Demant T; Jager H; Dieterle C; Bogner JR; Landgraf R; Goebel FD; Infektionsambulanz, Medizinische Poliklinik, Ludwig-Maximilians; Universitat Munchen, Germany.
BACKGROUND: The use of protease inhibitors in the treatment of HIV-1 infection is associated with the new onset of diabetes mellitus, hyperlipidaemia and lipodystrophy. It is unclear whether these findings are coincidental or whether they reflect a causative effect


Do viral load and CD8 cell count at initiation of tritherapy influence the increase of CD4 T-cell count?
AIDS. 1998 Oct 22;12(15):F175-9. Unique Identifier : AIDSLINE MED/99030024
Keita-Perse O; Roger PM; Pradier C; Pugliese P; Cottalorda J; Dellamonica P; Service des Maladies Infectieuses et Tropicales, Hopital; l'Archet 1, Nice, France.
BACKGROUND: Tritherapies including protease inhibitors improve clinical status and usually increase CD4 T cell count. However, the dissociation between the marked decreases in viral load and the incomplete restoration of CD4 cell counts with a three-drug combination


Resistance of HIV-1 to antiretroviral agents in blood and seminal plasma: implications for transmission.
AIDS. 1998 Oct 22;12(15):F181-9. Unique Identifier : AIDSLINE +
Eron JJ; Vernazza PL; Johnston DM; Seillier-Moiseiwitsch F; Alcorn TM; Fiscus SA; Cohen MS; Department of Medicine, University of North Carolina at Chapel; Hill, 27599-7030, USA.
OBJECTIVES: To evaluate blood and genital secretions from HIV-infected men for HIV-1 resistant to antiretroviral agents. DESIGN: A longitudinal study of 11 men with HIV infection and persistent detectable HIV RNA levels in blood and semen on antiretroviral therapy. METHODS: HIV-1 from the blood and seminal plasma, obt


Individual prognoses of long-term responses to antiretroviral treatment based on virological, immunological and pharmacological parameters measured during the first week under therapy.
AIDS. 1998 Oct 22;12(15):F191-6. Unique Identifier : AIDSLINE MED/99030026
Mueller BU; Zeichner SL; Kuznetsov VA; Heath-Chiozzi M; Pizzo PA; Dimitrov DS; HIV and AIDS Malignancy Branch, National Cancer Institute, NIH,; Bethesda, MD 20892, USA.
OBJECTIVE: To predict long-term (12 weeks or longer) virological responses to antiretroviral treatment from measurements made during the first few days on therapy. METHODS: Forty-one HIV-1-infected children were treated with ritonavir for 12 weeks fol


Antiretroviral drugs and the central nervous system [editorial]
AIDS. 1998 Oct 22;12(15):1941-55. Unique Identifier : AIDSLINE MED/99030027
Enting RH; Hoetelmans RM; Lange JM; Burger DM; Beijnen JH; Portegies P
Recruitment of the TATA-binding protein to the HIV-1 promoter is a limiting step for Tat transactivation.
AIDS. 1998 Oct 22;12(15):1957-64. Unique Identifier : AIDSLINE MED/99030028
Majello B; Napolitano G; Lania L; Department of Genetics, Molecular and General Biology, University; of Naples Federico II, Italy.
OBJECTIVES: To examine the functional interaction between HIV-1 Tat protein and the TATA-binding protein (TBP). DESIGN: HIV long terminal repeat reporter plasmids were cotransfected into mammalian and Drosophila insect cells with expression vectors encoding Tat and vectors encoding TBP either alone or linked to an het


Effect of malabsorption on nutritional status and resting energy expenditure in HIV-infected patients.
AIDS. 1998 Oct 22;12(15):1965-72. Unique Identifier : AIDSLINE MED/99030029
Jimenez-Exposito MJ; Garcia-Lorda P; Alonso-Villaverde C; de Virgala CM; Sola R; Masana L; Arija V; Izquierdo V; Salas-Salvado J; Human Nutrition Unit, Faculty of Medicine and Health Sciences,; Rovira i Virgili University, Reus, Spain.
OBJECTIVE: To assess the influence of malabsorption on nutritional status and energy expenditure in patients at different stages of HIV infection. DESIGN AND METHODS: Fifty HIV patients were classified into three groups: Group 1, HIV asymptomatic patients (n=17); Group 2, AIDS without opportunistic infection (n=16); G


Coexisting members of HIV-1 p17 gene quasispecies represent proteins with distinct antigenicity and immunogenicity.
AIDS. 1998 Oct 22;12(15):1973-81. Unique Identifier : AIDSLINE MED/99030030
Birk M; Flock JI; Sonnerborg A; Sallberg M; Division of Clinical Virology, Karolinska Institute, Huddinge; University Hospital, Sweden.
BACKGROUND: Despite the comparatively conserved nature of the HIV-1 gag gene, countless quasispecies of the p17 gene coexist in HIV-1-infected patients. It is not known if the minor genetic differences in quasispecies will affect immune recognition. OBJECTIVE: To characterize the antigenicity and immunogenicity of thr


Experience with a cross-study endpoint review committee for AIDS clinical trials. Terry Beirn Community Programs for Clinical Research on AIDS.
AIDS. 1998 Oct 22;12(15):1983-90. Unique Identifier : AIDSLINE MED/99030031
Green LA; Rhame FS; Price RW; Perlman DC; Capps LG; Sampson JH; Deyton LR; Schnittman SM; Fisher EJ; Bartsch GE; Krum EA; Neaton JD; CPCRA Statistical Center, University of Minnesota, Minneapolis; 55414, USA.
OBJECTIVES: To describe the methods and results of a standardized system for clinical endpoint determination for defining and reviewing endpoints in clinical trials for HIV-infected individuals. DESIGN: A system was developed utilizing standard definitions for the 24 diagnoses or clinical events that serve as trial en


HIV-1 RNA, CD4 cell count and the risk of progression to AIDS and death during treatment with HIV-1 reverse transcriptase inhibitors.
AIDS. 1998 Oct 22;12(15):1991-7. Unique Identifier : AIDSLINE MED/99030032
Staszewski S; DeMasi R; Hill AM; Dawson D; Klinikikum der Johann Wolfgang - Goethe Universitat, Frankfurt,; Germany.
CONTEXT: There is little information available on the correlation between HIV-1 RNA level, CD4 cell count and the risk of progression to AIDS or death during treatment with reverse transcriptase inhibitors. OBJECTIVES: To define the correlation between HIV-1 RNA level, CD4 cell count and the 1 year risk of progression


Efficacy and safety of stavudine and didanosine combination therapy in antiretroviral-experienced patients.
AIDS. 1998 Oct 22;12(15):1999-2005. Unique Identifier : AIDSLINE MED/99030033
Raffi F; Reliquet V; Auger S; Besnier JM; Chennebault JM; Billaud E; Michelet C; Perre P; Lafeuillade A; May T; Billaudel S; Department of Infectious Diseases, University Hospital, Nantes,; France.
OBJECTIVES: To assess the efficacy, tolerance, and safety of combination antiretroviral therapy with didanosine and stavudine in HIV-infected patients with CD4+ cell counts > 100 x 10(6)/l and HIV plasma RNA > 10(4) copies/ml previously treated with o


Multiple dideoxynucleoside analogue-resistant (MddNR) HIV-1 strains isolated from patients from different European countries.
AIDS. 1998 Oct 22;12(15):2007-15. Unique Identifier : AIDSLINE MED/99030034
Schmit JC; Van Laethem K; Ruiz L; Hermans P; Sprecher S; Sonnerborg A; Leal M; Harrer T; Clotet B; Arendt V; Lissen E; Witvrouw M; Desmyter J; De Clercq E; Vandamme AM; Rega Institute for Medical Research, Katholieke Universiteit; Leuven, Belgium.
OBJECTIVE: To study the prevalence of multiple dideoxynucleoside (ddN)-resistant (MddNR) HIV-1 in European patients under treatment with multiple ddN analogues, and to characterize MddNR strains genotypically and phenotypically. DESIGN AND METHODS: Blood samples from patients after > or = 6 months of treatment with mu


Purified protein derivative testing and tuberculosis preventive therapy for HIV-infected patients in New York City.
AIDS. 1998 Oct 22;12(15):2017-23. Unique Identifier : AIDSLINE MED/99030035
Sackoff JE; Torian LV; Frieden TR; Brudney KF; Menzies IB; New York City Department of Health, Office of AIDS Research, New; York 10013, USA.
OBJECTIVE: To determine whether Centers for Disease Control and Prevention recommendations for purified protein derivative (PPD) testing and tuberculosis (TB) preventive therapy for PPD-positive patients are implemented in HIV clinics. DESIGN: Retrospective medical chart review. SETTING: Ten hospital-based HIV clinics


Detection of high nerve growth factor serum levels in AIDS-related and -unrelated Kaposi's sarcoma patients.
AIDS. 1998 Oct 22;12(15):2025-9. Unique Identifier : AIDSLINE MED/99030036
Pica F; Volpi A; Barillari G; Fraschetti M; Franzese O; Vullo V; Garaci E; Department of Experimental Medicine and Biochemical Sciences,; University Tor Vergata, Rome, Italy.
OBJECTIVE: Nerve growth factor (NGF) is an autocrine survival factor for memory B lymphocytes. As functional B-cell deregulation is present during HIV infection, NGF serum levels were measured in HIV-infected patients and compared with the patients clinical features. DESIGN: Sera from 48 consecutive HIV-infected pati


Changes in use of antiretroviral therapy in regions of Europe over time. EuroSIDA Study Group.
AIDS. 1998 Oct 22;12(15):2031-9. Unique Identifier : AIDSLINE MED/99030037
Kirk O; Mocroft A; Katzenstein TL; Lazzarin A; Antunes F; Francioli P; Brettle RP; Parkin JM; Gonzales-Lahoz J; Lundgren JD; Coordinating Centre for EuroSIDA, Hvidovre Hospital, Copenhagen,; Denmark.
OBJECTIVES: To analyse use of antiretroviral therapy within Europe between 1994 and 1997. DESIGN: From September 1994, the EuroSIDA study (cohorts I-III) has prospectively followed unselected HIV-infected patients from 50 clinical centres in 17 European countries (total, 7230). METHODS: Patients under follow-up at hal


Incidence of HIV and sexually transmitted diseases (STD) in a cohort of HIV-negative men who have sex with men (MSM).
AIDS. 1998 Oct 22;12(15):2041-8. Unique Identifier : AIDSLINE MED/99030038
Tabet SR; Krone MR; Paradise MA; Corey L; Stamm WE; Celum CL; Department of Medicine, School of Medicine, University of; Washington, Seattle, USA.
OBJECTIVE: To determine the prevalence of sexually transmitted diseases (STD) and incidence of and risk factors for STD, including HIV-1, among a cohort of HIV-negative men who have sex with men (MSM). SETTING: Seattle, Washington, United States . PARTICIPANTS: Prospective cohort of 578


Estimating HIV incidence from age-specific prevalence data: comparison with concurrent cohort estimates in a study of male factory workers, Harare, Zimbabwe.
AIDS. 1998 Oct 22;12(15):2049-58. Unique Identifier : AIDSLINE MED/99030039
Gregson S; Machekano R; Donnelly CA; Mbizvo MT; Anderson RM; Katzenstein DA; Wellcome Trust Centre for the Epidemiology of Infectious Disease,; Zoology Department, Oxford University, UK.
OBJECTIVE: To compare HIV incidence estimates from cross-sectional age-specific prevalence data with concurrent cohort estimates and to examine the sensitivity of the estimates to changes in age-categorization and survivorship assumptions. METHODS: Two previously described methods of estimating HIV incidence from cros


Prevalence and incidence rate of HIV, hepatitis B and C among drug users on methadone maintenance treatment in Geneva between 1988 and 1995.
AIDS. 1998 Oct 22;12(15):2059-66. Unique Identifier : AIDSLINE MED/99030040
Broers B; Junet C; Bourquin M; Deglon JJ; Perrin L; Hirschel B; Division of Infectious Diseases, University Hospital, Geneva,; Switzerland.
OBJECTIVES: To evaluate the prevalence and incidence rates of infection with HIV, hepatitis B (HBV) and hepatitis C (HCV), in a cohort of drug users (DU) in Geneva, Switzerland . DESIGN: Prospective open cohort study. SETTING: Private methadone maintenance treatment (MMT) progr


Classic Kaposi's sarcoma in Jews living in Israel, 1961-1989: a population-based incidence study.
AIDS. 1998 Oct 22;12(15):2067-72. Unique Identifier : AIDSLINE MED/99030041
Iscovich J; Boffetta P; Winkelmann R; Brennan P; Azizi E; Israel Cancer Registry, Ministry of Health, Jerusalem.
BACKGROUND: The incidence of classic Kaposi s sarcoma (CKS) has been reported to be high in Jewish populations, mostly born in Eastern Europe. OBJECTIVE: To describe the incidence on CKS in Israeli Jews and to determine differences in incidence according to their geography origin. DESIGN: We analysed data on 1098 inci


Identification of a novel HLA-A24-restricted cytotoxic T-lymphocyte epitope derived from HIV-1 Gag protein [letter]
AIDS. 1998 Oct 22;12(15):2073-4. Unique Identifier : AIDSLINE MED/99030042
Ikeda-Moore Y; Tomiyama H; Ibe M; Oka S; Miwa K; Kaneko Y; Takiguchi M
Predictors of undetectable HIV plasma viral load in 250 HIV-positive women receiving care [letter]
AIDS. 1998 Oct 22;12(15):2075-6. Unique Identifier : AIDSLINE MED/99030043
Dickinson BP; Mitty JA; Mylonakis E; Rich JD; Merriman NA; Tashima KT; Carpenter CC; Flanigan TP
False positives for HIV using commercial viral load quantification assays [letter]
AIDS. 1998 Oct 22;12(15):2076-7. Unique Identifier : AIDSLINE MED/99030044
de Mendoza C; Holguin A; Soriano V
Protease inhibitor-associated hyperinsulinaemia [letter]
AIDS. 1998 Oct 22;12(15):2077-9. Unique Identifier : AIDSLINE MED/99030045
Martinez E; Casamitjana R; Conget I; Gatell JM
Is treatment with ritonavir a risk factor for myocardial infarction in HIV-infected patients? [letter]
AIDS. 1998 Oct 22;12(15):2079-80. Unique Identifier : AIDSLINE MED/99030046
Eriksson U; Opravil M; Amann FW; Schaffner A
Pharmacokinetic interaction between the proton pump inhibitor omeprazole and the HIV protease inhibitor indinavir [letter]
AIDS. 1998 Oct 22;12(15):2080-2. Unique Identifier : AIDSLINE MED/99030047
Burger DM; Hugen PW; Kroon FP; Groeneveld P; Brinkman K; Foudraine NA; Sprenger H; Koopmans PP; Hekster YA
High incidence of nevirapine-associated rash in HIV-infected Chinese [letter]
AIDS. 1998 Oct 22;12(15):2082-3. Unique Identifier : AIDSLINE MED/99030048
Ho TT; Wong KH; Chan KC; Lee SS
Reversal of abnormalities of neutrophil adhesion molecule expression in HIV infection following protease inhibitor therapy [letter]
AIDS. 1998 Oct 22;12(15):2083-4. Unique Identifier : AIDSLINE MED/99030049
Moore DA; Henderson D; Gotch F; Gazzard B
Genotypic changes in DNA fingerprinting patterns of Mycobacterium tuberculosis strains from HIV-positive persons in Sardinia.
AIDS. 1998 Oct 22;12(15):2084-6. Unique Identifier : AIDSLINE MED/99030050
Sechi LA; Zanetti S; Dupre I; Aceti A; Sanguinetti M; Fadda G
Secondary prophylaxis for Leishmania infection in an HIV-positive patient [letter]
AIDS. 1998 Oct 22;12(15):2086-7. Unique Identifier : AIDSLINE MED/99030051
Orlando G; Del Sorbo F; Corbellino M; Schiavini M; Cargnel A
Participatory action research for sustaining individual and community change: a model of HIV prevention education.
AIDS Educ Prev. 1998 Oct;10(5):387-402. Unique Identifier : AIDSLINE MED/99016318
Stevens PE; Hall JM; University of Wisconsin-Milwaukee School of Nursing, Health; Maintenance Department 53201, USA.
The authors describe the implementation, results, and evaluations of a participatory action research project in which they used qualitative methods to do HIV prevention education with lesbians and bisexual women. This grassroots project combined collective consciousness-raising, qualitative field interviewing, and ind


Relationship of HIV testing and high-risk behaviors among clients in methadone maintenance treatment.
AIDS Educ Prev. 1998 Oct;10(5):403-16. Unique Identifier : AIDSLINE MED/99016319
Grella CE; Campos M; Anglin MD; UCLA Drug Abuse Research Center 90024, USA.
This article reports on the association between frequency of HIV testing and high-risk behaviors among 339 individuals in the Los Angeles Enhanced Methadone Maintenance Project. Individuals who reported taking three or more HIV tests prior to entering treatment (45% of the sample) were more likely to know someone who


Continuing medical education versus clinic-based STD and HIV education interventions for primary care service providers: replication and extension.
AIDS Educ Prev. 1998 Oct;10(5):417-32. Unique Identifier : AIDSLINE MED/99016320
Neff JA; Gaskill SP; Prihoda TJ; Weiner RV; Rydel KB; University of Tennessee College of Social Work, Nashville 37203,; USA. jneff1@utk.edu
An evaluation of a 2-day sexually transmitted disease (STD) and HIV and AIDS curriculum for primary care providers is presented which compares large scale continuing medical education (CME) conferences with smaller clinic workshop (CW) models with regard to short-term (2-month) and long-term (10-month) program effects


Effectiveness of a specialized vs. traditional AIDS education program attended by homeless and drug-addicted women alone or with supportive persons.
AIDS Educ Prev. 1998 Oct;10(5):433-46. Unique Identifier : AIDSLINE MED/99016321
Nyamathi A; Flaskerud J; Keenan C; Leake B; University of California at Los Angeles School of Nursing; 90095-6918, USA.
This research examined the impact of including a supportive person on the outcomes of two culturally sensitive AIDS education programs, an education-only (traditional) program and a program combining education with self-esteem and coping enhancement (specialized). Research participants in this quasi-experimental study


Perceived AIDS risk among adult arrestee injection drug users in Los Angeles county.
AIDS Educ Prev. 1998 Oct;10(5):447-64. Unique Identifier : AIDSLINE MED/99016322
Henson KD; Longshore D; Kowalewski MR; Anglin MD; Annon K; Department of Sociology and Anthropology, Loyola University,; Chicago, IL 60626, USA. khenson@luc.edu
In this paper we examine the determinants of perceived risk for getting HIV and AIDS among adult Los Angeles arrestees reporting any lifetime injection drug use (N = 958). Our sample, drawn from the Drug Use Forecasting program, is 60% male and 40% female. Higher rates of reported risky drug and sexual behaviors than


Acceptability of the female condom among STD clinic patients.
AIDS Educ Prev. 1998 Oct;10(5):465-80. Unique Identifier : AIDSLINE MED/99016323
el-Bassel N; Krishnan SP; Schilling RF; Witte S; Gilbert L; Social Intervention Group, Columbia University School of Social; Work, New York, NY 10025, USA. ne5@Columbia.edu
This study examines the acceptability of the female condom among African American and Latino patients from two inner-city sexually transmitted disease (STD) clinics through focus group discussions. Prior to the initial focus group sessions, 90% (n = 90) had heard about the female condom, 8% (n = 8) had seen it, and 2%


[Mycobacterium tuberculosis drug resistance in patients with HIV and pulmonary tuberculosis infections in Rome: 1987-1996]
Ann Ital Med Int. 1998 Jul-Sep;13(3):139-45. Unique Identifier : AIDSLINE MED/99076666
Palmieri F; Pellicelli AM; Girardi E; Rianda A; Bordi E; Festa A; Catania S; D'Amato C; II Divisione, IRCCS L. Spallanzani di Roma.
A retrospective chart review was performed on 118 HIV infected patients with pulmonary tuberculosis hospitalized between 1987 and 1996 in a tertiary care center for Infectious Diseases in Rome. The aims of this study were: a) to evaluate global prevalence of and risk factors for drug-resistant Mycobacterium tuberculos


Lactobacillus casei pneumonia and sepsis in a patient with AIDS. Case report and review of the literature.
Ann Ital Med Int. 1998 Jul-Sep;13(3):180-2. Unique Identifier : AIDSLINE MED/99076674
Rogasi PG; Vigano S; Pecile P; Leoncini F; U.O. Malattie Infettive, Azienda Ospedaliera Careggi di Firenze.
Lactobacilli are ubiquitous gram-positive anaerobic rods present in the normal bacterial flora of the mouth, vagina and gastrointestinal tract. Although they are usually non pathogenic, serious infections have occasionally been described in transplant recipients or severely ill patients. Only 4 cases have been reporte


Studies on the effects of truncating alpha-helix E' of p66 human immunodeficiency virus type 1 reverse transcriptase on template-primer binding and fidelity of DNA synthesis.
Biochemistry. 1998 Nov 24;37(47):16636-44. Unique Identifier : AIDSLINE PDB/2HMI
Menendez-Arias L; Centro de Biologia Molecular "Severo Ochoa", CSIC-Universidad; Autonoma de Madrid, Spain. lmenedez@cbm.uam.es
The role of alpha-helix E of the RNase H domain of human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) in template-primer binding and fidelity of DNA synthesis was investigated by using a series of mutant enzymes with deletions of 4, 8, 12, 16, and 20 amino acids at the C-terminal end of the 66 kDa s


Genetic vaccination-induced immune responses to the human immunodeficiency virus protein Rev: emergence of the interleukin 2-producing helper T lymphocyte.
Hum Gene Ther. 1998 Oct 10;9(15):2187-96. Unique Identifier : AIDSLINE MED/99008305
Chan SY; Louie MC; Piccotti JR; Iyer G; Ling X; Yang ZY; Nabel GJ