1991

Surgery in the age of AIDS : prevention of viral transmission in the operating room. [videorecording]: [Seattle, Wash.] : Novela Health Foundation, c1990 1 videocassette (20 min.) : sd., col. ; 1/2 in. + 1 guide + 1 poster Unique Identifier : AIDSLINE AV/9100026A; Rabinowitz PM; Committee; (Producer) Training program includes a film based on documentation of actual surgeries, interviews with operating room staff, demonstrations of proper technique, and risk reduction guidelines; a manual providing in-depth review of viral transmission in the operating room setting, with background readings; and a poste
Guidelines for the development of a national AIDS prevention and control programme.: Geneva : World Health Organization ; Albany, NY : WHO Publications Center USA [distributor], 1988 iv, 27 p (WHO AIDS series, ISSN 1011-577 ; 1) Unique Identifier : AIDSLINE CAT/9100056
Social aspects of the prevention of AIDS, study A.: [Sydney] : Macquarie University, 1988 printing v Unique Identifier : AIDSLINE CAT/9100392; Connell RW
Tuberculosis in Australia and New Zealand in the 1990s.: [Canberra, A.C.T.] : National Health and Medical Research Council, c1989 i, 61 p. : ill Unique Identifier : AIDSLINE CAT/9100136; Patel A; Streeton J; Session
Mathematical and statistical approaches to AIDS epidemiology.: Berlin ; New York : Springer-Verlag, c1989 viii, 405 p. : ill (Lecture notes in biomathematics ; 83) Unique Identifier : AIDSLINE CAT/9100354; Castillo-Chavez C
Protocol 6, HIV-related training needs, programs, and costs.: Rockville, MD (18-12 Parklawn Bldg., Rockville 20857) : U.S. Dept. of Health and Human Services, Public Health Service, National Center for Health Services Research and Health Care Technology Assessment, [1989] iii, 100 p (NCHSR program note) Unique Identifier : AIDSLINE CAT/9100247; Hall TL; Technology Assessment (U.S.); Education
Epitaphs for the living : words and images in the time of AIDS. 1st ed.: Dallas : Southern Methodist University Press, 1989 xviii, 68 leaves : chiefly ill Unique Identifier : AIDSLINE CAT/9100188; Howard B
Selected and annotated bibliography for 1988 on oral problems related to the HIV infection.: Copenhagen : WHO Collaborating Centre for Oral Manifestations of the Human Immunodeficiency Virus Infection at Dental Dept., University Hospital, Copenhagen in collaboration with the WHO Global Programme on AIDS and the Oral Health Unit and the EEC Clearinghouse on Oral Problems Related to the HIV Infection, 1990 48 p Unique Identifier : AIDSLINE CAT/9100256; Pindborg JJ; Bibliography of references covering the literature dealing with oral problems related to the HIV infection. Topical arrangement. Entries give bibliographical information and annotations of single or related articles. Author index.
Selected and annotated bibliography on oral manifestations of the HIV infection, 1981-1987.: Copenhagen : WHO Collaborating Centre for Oral Manifestations of the Human Immunodeficiency Virus Infection at Dental Dept., University Hospital, Copenhagen in collaboration with the WHO Global Programme on AIDS and the Oral Health Unit and the EEC Clearinghouse on Oral Problems Related to the HIV Infection, 1990 54 p Unique Identifier : AIDSLINE CAT/9100257; Pindborg JJ; Intended to pinpoint either the first description of an oral manifestation or decisive new discoveries related to the oral manifestations. Topical arrangement. Entries give bibliographical information and annotation. Index.
The:guide to living with HIV infection : developed at the Johns Hopkins AIDS Clinic.: Baltimore : Johns Hopkins University Press, c1991 xii, 337 p Unique Identifier : AIDSLINE CAT/9100003; Bartlett JG; Finkbeiner AK
PLASMAPHERESIS FOLLOWED BY IMMUNOGLOBULIN INFUSION FOR TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) INFECTED PATIENTS WITH HYPERGAMMAGLOBULINAEMIA: Int J Immunotherapy; 4(4):229-34 1988. Unique Identifier : AIDSLINE ICDB/90657982; Rogna S; Puppo F; Torresin A; Stagnaro R; Setti M; Pierri I; Orlando G; Indiveri F; Inst. of Internal Medicine, Univ. of Genoa, Genoa, Italy; AIDS patients (pts) often develop a conspicuous, although functionally ineffective, hypergammaglobulinemia. The authors have treated 9 pts affected by AIDS or AIDS-related diseases with repeated courses of plasma exchange coupled with immunoglobulin infusions. The schedule of each course was as follows: one apheretic
GENETIC REGULATION OF HIV BY DNA VIRUS TRANS-ACTING PROTEINS AND SODIUM BUTYRATE: Diss Abstr Int [B]; 50(1):61 1989. Unique Identifier : AIDSLINE ICDB/90658129; Bohan CA; Emory Univ.; Gene expression of HIV-1, the etiological agent of AIDS, has been shown to be regulated by HIV-1 nonstructural regulatory polypeptides and by chemical and DNA virus modulators. Using a transient expression system, the herpes simplex virus (HSV) ICP4, human cytomegalovirus (HCMV) IE
HEALTH HAZARDS OF NITRITE INHALANTS: Available from National Technical Information Service, Springfield, VA as NTIS/PB89-125496, 126 p., 1989.. Unique Identifier : AIDSLINE ICDB/90659323; Haverkos HW; Dougherty JA; National Inst. on Drug Abuse, Rockville, MD; Contents: Nitrite inhalants: historical perspective; Fate and toxicity of butyl nitrites; Acute toxicity of nitrite inhalants; Indications from animal and chemical experiments of a carcinogenic role for isobutyl nitrite; Toxicity of inhaled isobutyl nitrite in BALB/c mice: systemic and immunotoxic studies; Altered T-c
ANTIBODIES TO HTLV-1: DETECTION, SEROPREVALENCE IN BLOOD DONORS, AND SEROLOGIC RELATIONSHIP TO HIV-1: Diss Abstr Int [B]; 50(4):1242 1989. Unique Identifier : AIDSLINE ICDB/90659891; Fang C; George Washington Univ.; Sera from 39,898 blood donors at eight blood centers were tested for HTLV-1 antibody using two enzyme immunoassays (EIA) after an evaluation on six test kits. Sera testing initially reactive (IR) were retested in duplicate by both EIAs. Sera testing repeatedly reactive (RR) were further tested by two Western blots (WB
OLIGODEOXYNUCLEOTIDES AS ANTISENSE INHIBITORS OF GENE EXPRESSION: THERAPEUTIC IMPLICATIONS. JUNE 18-21, 1989, ROCKVILLE, MD: Oligodeoxynucleotides as Antisense Inhibitors of Gene Expression: Therapeutic Implications. June 18-21, 1989, Rockville, MD, National Cancer Institute, National Institute of Allergy and Infectious Diseases, 1989.. Unique Identifier : AIDSLINE ICDB/90660171; Anonymous; No affiliation given; A symposium on therapeutic implications of oligodeoxynucleotides as antisense inhibitors of gene expression, held June 18-21, 1989, in Rockville, MD, was cosponsored by NCI and the National Institute of Allergy and Infectious Diseases. Speakers presentations and poster sessions are summarized. Topics include the foll
RECOMBINANT IMMUNOBLOT ASSAY FOR THE DETECTION OF ANTIBODIES TO HIV: HIV Detection by Genetic Engineering Methods. Luciw PA and Steimer KS, eds. New York, Marcel Dekker, p. 121-41, 1989.. Unique Identifier : AIDSLINE ICDB/90660258; Truett MA; Chien DY; Calarco TL; DiNello RK; Polito AJ; Chiron Corporation, Emeryville, CA; The Chiron recombinant immunoblot assay (CRIA) was developed to detect antibodies to HIV in human serum. Four recombinant viral antigens were used: p24, the major core protein and gag gene product; p31, a polypeptide from the endonuclease region of the pol gene; and two recombinant envelope polypeptides expressed from
IMMUNOREACTIVITY OF AIDS/ARC PATIENT SERA WITH SYNTHETIC OLIGOPEPTIDES FROM HIV GP41: HIV Detection by Genetic Engineering Methods. Luciw PA and Steimer KS, eds. New York, Marcel Dekker, p. 143-60, 1989.. Unique Identifier : AIDSLINE ICDB/90660259; Rosen JI; Hom YL; Whalley AS; Smith RS; Naso RB; Johnson and Johnson Biotechnology Center, La Jolla, CA; In an effort to define critical, immunologically active epitopes for the development of both diagnostic and therapeutic products, 20 oligopeptides (each 15-20 amino acids in length) were synthesized from the published sequences of gag and env-lor genes of human lymphotropic virus-III. When these peptides were tested a
AN ASSAY FOR THE DETECTION OF HIV SEROPOSITIVE INDIVIDUALS BASED ON A CHEMICALLY SYNTHESIZED PEPTIDE: HIV Detection by Genetic Engineering Methods. Luciw PA and Steimer KS, eds. New York, Marcel Dekker, p. 161-7, 1989.. Unique Identifier : AIDSLINE ICDB/90660260; Cosand WL; Houghton RL; Goldstein LC; Oncogen, Seattle, WA; An HIV-antibody immunoassay is described that employs peptide 39, which corresponds to amino acids 584-609 of the env precursor protein of the Bru LAV strain of HIV. Peptide 39 was synthesized by solid phase methodology. Serum or plasma samples were defined as seropositive or negative by the LAV EIA (Genetic Systems)
NEEDLE AND SYRINGE EXCHANGE AS A METHOD OF AIDS EPIDEMIC CONTROL: AIDS Updates; 2(5):1-8 1989. Unique Identifier : AIDSLINE ICDB/90660518; Joseph SC; Des Jarlais DC; Dept. of Health, New York, NY; The use of needle and syringe exchanges as a method of preventing HIV infection among people who inject illicit drugs is reviewed, and a case history of the pilot exchange program in New York City is presented. In addition to reducing the spread of HIV infection, syringe exchange programs provide for safe disposal of
HIV AND AIDS: PATHOGENESIS, THERAPY AND VACCINE: J Cell Biochem; (Suppl 14D):77-181 1990. Unique Identifier : AIDSLINE ICDB/90665936; Anonymous; No affiliation given; A symposium on HIV and AIDS, part of the UCLA series, was held in Keystone, Colorado, from March 31 to April 6, 1990. The symposium covered HIV regulation and pathogenesis; cellular targets for HIV infection; genetic and biologic variants of HIV; pathogenic mechanisms and immune responses in HIV; molecular targets for
RETROVIRAL PATHOGENESIS AND VACCINE DEVELOPMENT IN MACACA NEMESTRINA AND RETROVIRAL-INDUCED ALTERATIONS OF INTRACELLULAR CALCIUM METABOLISM FROM CELLS OF HEMATOPOIETIC ORIGIN: Diss Abstr Int [B]; 50(12):5536 1990. Unique Identifier : AIDSLINE ICDB/90666765; Dezzutti CS; Ohio State Univ.; Five pig-tailed macaques (Macaca nemestrina) were vaccinated twice, 4 wk apart, with a human T-cell lymphotropic virus type I (HTLV-I) subunit vaccine. 4 wk post-vaccination, the vaccinated macaques and five control monkeys were challenged with a simian T-cell lymphotropic virus type I (STLV-I)-infected cell line. Fol
2',3'-DIDEOXYCYTIDINE AND HUMAN IMMUNODEFICIENCY VIRUS REVERSE TRANSCRIPTASE: Diss Abstr Int [B]; 50(1):117 1989. Unique Identifier : AIDSLINE ICDB/90658142; Starnes MC; Univ. of North Carolina, Chapel Hill; 2 ,3 -Dideoxycytidine (ddCyd) is a candidate for clinical trial in the treatment of AIDS, as a result of its potent inhibition of HIV replication. The cellular metabolism and cytotoxicity of ddCyd are discussed, as well as the interaction of ddCTP and other nucleotide and pyrophosphate analogs with mammalian DNA polym
INHIBITORS OF VIRAL NUCLEIC ACID POLYMERASES: PYROPHOSPHATE ANALOGUES: ACS Symp Ser; (401):1-16 1989. Unique Identifier : AIDSLINE ICDB/90666472; McKenna CE; Levy JN; Khawli LA; Harutunian V; Ye TG; Starnes MC; Bapat A; Cheng YC; Dept. of Chemistry, Univ. of Southern California, Los Angeles, CA; 90089-0744; Virus-specific enzymes essential for viral nucleic acid replication or related functions are targets for inhibition by substrate or product nucleotide analogs in which one or more P-O bonds are replaced by a P-C bond. The simplest examples of these are PFA (phosphonoformic acid) and PAA (phosphonoacetic acid), represe
ISOLATION AND CHARACTERIZATION OF ANTIGENIC VARIANTS OF MURINE RETROVIRUSES: Diss Abstr Int [B]; 51(1):140 1990. Unique Identifier : AIDSLINE ICDB/90667085; Pozsgay JM; Univ. of Pennsylvania; The data presented in this thesis have focused on the isolation and characterization of variant viruses of a murine leukemia virus that exhibit changes in antigenicity following in vivo passage in adult immunocompetent hosts. Although antigenic variation has been described in other species, the results described in th
Search for an AIDS virus: animal models [news]: Microbiol Sci. 1984 May;1(2):54. Unique Identifier : AIDSLINE MED/91026462; Curtin ME
Mycoses complicating AIDS.: Microbiol Sci. 1984 Dec;1(9):219-23. Unique Identifier : AIDSLINE MED/91026509; Stenderup A; Schonheyder H; Institute of Medical Microbiology, University of Aarhus, Denmark.
The first human retroviruses: are there others?: Microbiol Sci. 1985;2(4):97-8, 101-4. Unique Identifier : AIDSLINE MED/91026543; Gallo RC; Reitz MS Jr; Laboratory of Tumor Cell Biology, National Cancer Institute,; Bethesda, Maryland 20205.; Three related, but very different, retroviruses have recently been identified in man. Human T-cell leukaemia virus (HTLV) type I apparently causes adult T-cell leukaemia. HTLV type II has been isolated only rarely and has not been identified with a disease. HTLV type III is very likely the causative agent in acquired
Pathogenetic implications of neuropathological findings in the AIDS dementia complex.: Psychopharmacol Bull. 1988;24(3):307-10. Unique Identifier : AIDSLINE MED/91046578; Brew BJ; Rosenblum M; Price RW
Mechanisms of brain damage by HIV-1.: Psychopharmacol Bull. 1988;24(3):311-4. Unique Identifier : AIDSLINE MED/91046579; Gurney ME
AIDS as a neuropeptide disorder: peptide T, VIP, and the HIV receptor.: Psychopharmacol Bull. 1988;24(3):315-9. Unique Identifier : AIDSLINE MED/91046580; Pert CB; Ruff MR; Hill JM
HIV-1: neuropsychiatric manifestations and their treatment.: Psychopharmacol Bull. 1988;24(3):320-4. Unique Identifier : AIDSLINE MED/91046581; Bridge TP
Perspectives on infection with HIV-1 among intravenous drug users.: Psychopharmacol Bull. 1988;24(3):325-9. Unique Identifier : AIDSLINE MED/91046582; Vlahov D; Polk BF
Perspectives on the evolution of federal AIDS research policy.: Psychopharmacol Bull. 1988;24(3):330-3. Unique Identifier : AIDSLINE MED/91046583; Goodwin FK; Bridge TP; Ingraham LJ
[AIDS. Mass screening (news)]: Rev Infirm. 1988 Apr;38(7):10. Unique Identifier : AIDSLINE MED/91047612
AIDS: implications for dental hygienists.: Semin Dent Hyg. 1989 Dec;1(4):1-5, 7. Unique Identifier : AIDSLINE MED/91025567; Shuman D
[Recurrence of Varicella-zoster virus infection]: Pol Tyg Lek. 1989 Aug 21-28;44(34-35):801-2. Unique Identifier : AIDSLINE MED/91045372; Marczynska M; A case of Varicella-zoster virus re-infection in a 3.5-year child with the acute lymphoblastic leukemia is presented. This report aims at emphasizing a possibility of re-activation of the virus in younger and younger children with immunodeficiency. A clinical course may imitate chicken-pox creating diagnostic problems
[Occupational AIDS (news)]: Rev Infirm. 1989 Dec;39(20):6. Unique Identifier : AIDSLINE MED/91047652
[Examination gloves and AIDS (news)]: Soins. 1989 Dec;(531):60. Unique Identifier : AIDSLINE MED/91048120
[Jejunal biopsy in AIDS]: Arq Gastroenterol. 1989 Oct-Dec;26(4):100-4. Unique Identifier : AIDSLINE MED/91053782; Elia C; Oliveira AV; Madi K; Hospital Universitario Clementino Fraga Filho, Programa SIDA,; AIDS da Universidade Federal do Rio de Janeiro.; Histopathological changes in small bowel biopsy from 5 patients with acquired immunodeficiency syndrome are reported. The main abnormalities were villous atrophy, severe mononuclear infiltrate and enhanced regenerative activity with high number of mitosis in the crypts.
[Blood transfusions in maxillofacial surgery]: G Stomatol Ortognatodonzia. 1989 Jul-Dec;8(4):29-30. Unique Identifier : AIDSLINE MED/91034483; Deangeli R; De Angelis V; In the last few years a codification of maxillo-facial surgical techniques has been reached. This has been possible because of a close interaction among different specialists. The use of blood transfusion must be carefully evaluated because of the different risks involved. The transmission of infectious agents like HI
[Pathology of the oral cavity in patients with congenital coagulopathies and HIV infections]: G Stomatol Ortognatodonzia. 1989 Jul-Dec;8(4):31-4. Unique Identifier : AIDSLINE MED/91034485; Vicari T; Sartori MT; Mares M; Calzavara M; Girolami A; Beltrami A; Grandis M
Anaplastic astrocytoma in association with human immunodeficiency virus type 1 infection [letter]: Am J Emerg Med. 1990 Nov;8(6):565-7. Unique Identifier : AIDSLINE MED/91025247; Carrana EJ; Rossitch E; Moore MR; Funkenstein HH
[Interviews with HIV seropositive subjects identified at the time of blood donation: consequences for pre-donation interviews]: Rev Fr Transfus Hemobiol. 1990 Jul;33(4):239-48. Unique Identifier : AIDSLINE MED/91025298; Lefrere JJ; Paquez F; Duc A; Rouger P; Salmon C; Fondation Nationale de Transfusion Sanguine, Paris.; This study is based upon an interview with 31 individuals recently detected human immunodeficiency virus (HIV) seropositive through the systematic screening of blood donations. The location of the blood donation, the type of blood donor, the risk of HIV infection, were established. Questions dealt with the use of bloo
[The medical interview motivated by the discovery of markers of viral hepatitis permits the identification, in blood donors, of behavior at risk for HIV infection]: Rev Fr Transfus Hemobiol. 1990 Jul;33(4):249-58. Unique Identifier : AIDSLINE MED/91025299; Guillard A; Tirtaine C; Ouzan D; Follana R; Centre de Transfusion Sanguine des Alpes-Maritimes,; Saint-Laurent-du-Var.; From December 1988 to September 1989, 973 blood donors, deferred for anti-HBc reactivity, Ag-HBs positivity, elevated ALT, isolated or associated, but negative for anti-HIV, were interviewed in our blood center in the weeks after donation. Among these 973 donors, 53 (5.4%, 46 males, 7 females) were found at risk for H
[The polymerase chain reaction (PCR) in seronegative subjects at high risk for HIV infection (Report of a congress at San Francisco, June, 1990)]: Rev Fr Transfus Hemobiol. 1990 Jul;33(4):291-3. Unique Identifier : AIDSLINE MED/91025301; Lefrere JJ; I.N.T.S., Paris.
IgG subclass deficiency.: Immunodefic Rev. 1990;2(2):129-49. Unique Identifier : AIDSLINE MED/91026001; Preud'homme JL; Hanson LA; Laboratory of Immunology and Immunopathology (CNRS URA 1172),; University Hospital, Poitiers, France.; Although the occurrence of selective deficiencies of serum IgG subclasses has been known for 20 years, the large body of data presently available was collected only recently owing to the use of performing monoclonal antibodies. IgG subclass deficiency is frequent, both as an apparently isolated defect (about one fourt
Pediatric HIV infection: a review.: Immunodefic Rev. 1990;2(2):83-127. Unique Identifier : AIDSLINE MED/91026003; Calvelli TA; Rubinstein A; Department of Pediatrics, Albert Einstein College of Medicine,; Bronx, New York 10461.
A rapid method for the construction of synthetic genes using the polymerase chain reaction.: Biotechniques. 1990 Sep;9(3):298, 300. Unique Identifier : AIDSLINE MED/91026010; Dillon PJ; Rosen CA; Department of Molecular Oncology and Virology, Roche Institute of; Molecular Biology, Roche Research Center, Nutley, NJ 07110.
Sphere-linked immunodiagnostic assay (SLIDA): an electron microscopic method for detecting specific antibodies.: Biotechniques. 1990 Sep;9(3):342-50. Unique Identifier : AIDSLINE MED/91026022; Hari V; Baunoch D; Das P; Wayne State University, Detroit, MI 48202.; We have developed a sensitive method, sphere-linked immunodiagnostic assay, using specific antigens covalently bonded to microspheres for the detection of antibodies in serum. In this method, specific antigens, such as the capsid proteins of tobacco mosaic virus and tobacco etch virus, were independently, covalently b
Cytotoxic activity against HIV-infected monocytes by recombinant interleukin 2-activated natural killer cells.: AIDS Res Hum Retroviruses. 1990 Aug;6(8):1011-5. Unique Identifier : AIDSLINE MED/91026264; Melder RJ; Balachandran R; Rinaldo CR; Gupta P; Whiteside TL; Herberman RB; Department of Pathology, University of Pittsburgh, PA 15213.; Natural killer (NK) cells have long been known to aid in the control of viral infections by killing virus-infected cells, including those infected with human immunodeficiency virus (HIV). Among the possible NK-susceptible target cells in an infected individual, the monocyte/macrophages are of special significance sinc
Macrophage tropism of HIV-1.: AIDS Res Hum Retroviruses. 1990 Aug;6(8):1017-21. Unique Identifier : AIDSLINE MED/91026265; Gartner S; Popovic M; Primate Research Institute, Holloman AFB, NM 88330.; Both in vivo and in vitro studies clearly demonstrate that cells of the mononuclear phagocyte lineage are major hosts for human immunodeficiency virus type 1 (HIV-1) replication. Presumably these cells play a key role in the pathogenesis of acquired immunodeficiency syndrome (AIDS). To further delineate the interactio
Extrachromosomal HIV-1 DNA in persistently infected U937 cells.: AIDS Res Hum Retroviruses. 1990 Aug;6(8):1027-30. Unique Identifier : AIDSLINE MED/91026267; Pauza CD; Singh MK; Developmental Biology Laboratory, Salk Institute for Biological; Studies, San Diego, CA 92138-9216.; Persistent human immunodeficiency virus type 1 (HIV-1) infection of U937 monocytic cells resulted in the accumulation of novel forms of extrachromosomal viral DNA. These DNA species are larger than the genome size of HIV-1 and persist indefinitely. The extrachromosomal viral DNA species (E-DNA) were shown to be struct
Effects of GLQ223 on HIV replication in human monocyte/macrophages chronically infected in vitro with HIV.: AIDS Res Hum Retroviruses. 1990 Aug;6(8):1039-43. Unique Identifier : AIDSLINE MED/91026269; McGrath MS; Santulli S; Gaston I; Department of Medicine, University of California, San Francisco.; GLQ223 is a formulated version of tricosanthin, a single-chain ribosome-inactivating protein that was shown in earlier studies to inhibit human immunodeficiency virus (HIV) replication in T-lymphoblastoid cells and to decrease HIV p24 levels in HIV-infected monocyte-derived macrophages as measured by flow cytometry. T
Ability of anti-HIV agents to inhibit HIV replication in monocyte/macrophages or U937 monocytoid cells under conditions of enhancement by GM-CSF or anti-HIV antibody.: AIDS Res Hum Retroviruses. 1990 Aug;6(8):1051-5. Unique Identifier : AIDSLINE MED/91026271; Perno CF; Cooney DA; Currens MJ; Rocchi G; Johns DG; Broder S; Yarchoan R; National Cancer Institute, Bethesda, MD 20892.; Monocyte/macrophages (M/M) are an important target cell for human immunodeficiency virus (HIV) infection in the body. The study of HIV infection in these cells, however, is rather complicated because they represent a variable population, and because HIV entry and replication in M/M may be markedly influenced by a numb
Role of the monocyte-macrophage in influenza virus infection of lymphocytes: implications for HIV infection.: AIDS Res Hum Retroviruses. 1990 Aug;6(8):965-6. Unique Identifier : AIDSLINE MED/91026273; Mock DJ; Roberts NJ Jr; Department of Medicine, University of Rochester School of; Medicine, NY 14642.; Knowledge of the pathogenesis of viruses which are less virulent than human immunodeficiency virus (HIV) may provide valuable insights into the pathogenesis of HIV infection. Influenza virus, an enveloped RNA virus, infects monocyte-macrophages, although the infection is brief and abortive. Isolated purified lymphocyt
Macrophages as susceptible targets for HIV infection, persistent viral reservoirs in tissue, and key immunoregulatory cells that control levels of virus replication and extent of disease.: AIDS Res Hum Retroviruses. 1990 Aug;6(8):967-71. Unique Identifier : AIDSLINE MED/91026274; Meltzer MS; Nakamura M; Hansen BD; Turpin JA; Kalter DC; Gendelman HE; Department of Cellular Immunology, Walter Reed Army Institute of; Research, Washington, DC 20307-5100.; Although macrophages are major targets for human immunodeficiency virus (HIV) infection in vivo, study of HIV-macrophage interactions in vitro was hindered because many laboratory strains of HIV would not replicate in macrophages, and because survival of macrophages in culture was poor. Addition of purified macrophage
The effect of interleukin 4 (BSF-1) on infection of peripheral blood monocyte-derived macrophages with HIV-1.: AIDS Res Hum Retroviruses. 1990 Aug;6(8):973-6. Unique Identifier : AIDSLINE MED/91026275; Novak RM; Holzer TJ; Kennedy MM; Heynen CA; Dawson G; University of Illinois, Chicago 60612.; The effects of various cytokines were examined in an in vitro model of human immunodeficiency virus type 1 (HIV-1) infection of human peripheral blood monocyte-derived macrophages (MDM). Monocytes were obtained from blood of normal donors by Ficoll/hypaque gradient centrifugation and adherence. These cells were allowe
Antibody-enhanced infection of monocytes as the pathogenetic mechanism for severe dengue illness.: AIDS Res Hum Retroviruses. 1990 Aug;6(8):993-8. Unique Identifier : AIDSLINE MED/91026279; Kliks S; Cancer Research Institute, University of California, School of; Medicine, San Francisco 94143-0128.; Antibody-dependent enhancement of certain virus infections can occur in cells expressing Fc receptors. This mechanism plays an important pathogenetic role in the development of complications associated with dengue virus infection, including dengue hemorrhagic infection and dengue shock syndrome. The virulence of the v
FcR-mediated enhancement of HIV-1 infection by antibody.: AIDS Res Hum Retroviruses. 1990 Aug;6(8):999-1004. Unique Identifier : AIDSLINE MED/91026280; Takeda A; Ennis FA; Department of Medicine, University of Massachusetts Medical; School, Worcester 01655.; Although CD4 is a major receptor for human immunodeficiency virus (HIV) infection of cells, studied by ourselves and others clearly show that the Fc receptor (FcR) also plays a role in infection, perhaps in conjunction with other surface receptors. IgG antibodies to HIV-1 will enhance infectivity in cells (such as mon
Transforming properties of the HTLV-I tax gene.: Cancer Cells. 1990 Aug-Sep;2(8-9):281-3. Unique Identifier : AIDSLINE MED/91026787; Weiss RA; Schulz TF; Chester Beatty Laboratories, Institute of Cancer Research,; London, UK.
Treatment of acquired immunodeficiency syndrome.: Cancer Chemother Biol Response Modif. 1990;11:379-415. Unique Identifier : AIDSLINE MED/91026803; Yarchoan R; Pluda JM; Mitsuya H; Broder S
Mycotic aneurysm caused by group B streptococcus: a cautionary tale of management problems and a rare organism.: Br J Clin Pract. 1990 Sep;44(9):372-4. Unique Identifier : AIDSLINE MED/91027090; Burnet NG; Wilkinson RC; Evans DS; Surgical Unit, Royal Shrewsbury Hospital, Shropshire.; We report a case of mycotic aneurysm of the femoral artery which highlights the diagnostic features and management problems of the condition. Our patient required emergency ligation of the artery for life-threatening haemorrhage and subsequently his leg was not viable. The alternative treatment options of simple ligat
Acquired immunodeficiency syndrome (AIDS)--data as at 31 August 1990.: Wkly Epidemiol Rec. 1990 Sep 7;65(36):273-4. Unique Identifier : AIDSLINE MED/91027421
Acquired immunodeficiency syndrome (AIDS)--data as at 30 September 1990.: Wkly Epidemiol Rec. 1990 Oct 5;65(40):305-6. Unique Identifier : AIDSLINE MED/91027424
Surveillance of sexually transmitted diseases, 1989.: Wkly Epidemiol Rec. 1990 Oct 12;65(41):315-8. Unique Identifier : AIDSLINE MED/91027428
Sporadic HTLV-I associated adult T-cell leukaemia (ATL) in the U.K.: Br J Haematol. 1990 Sep;76(1):149-50. Unique Identifier : AIDSLINE MED/91027576; Wyld PJ; Tosswill JH; Mortimer PP; Weber JN; Inveresk Clinical Research Ltd., Riccarton, Edinburgh.
The continuous decrease in the number of SSPE annual cases ten years after compulsory anti-measles immunization.: Rev Roum Virol. 1990 Jan-Mar;41(1):13-8. Unique Identifier : AIDSLINE MED/91027598; Cernescu C; Popescu-Tismana G; Alaicescu M; Popescu L; Cajal N; St. S. Nicolau Institute of Virology, Bucharest, Romania.; The record of SSPE cases diagnosed immunochemically and serologically in our laboratory, standing for about 60% of the total new cases reported in our country, shows a significant decrease in the incidence in 1988-89 (from 5.21 new cases per year per million total population in 1987 to 1.82 cases in 1988). In 85% of t
Evaluation of efficacy of pooled sera in a human immunodeficiency virus antibody prevalence in population surveys.: Rev Roum Virol. 1990 Jan-Mar;41(1):45-51. Unique Identifier : AIDSLINE MED/91027604; Patrascu IV; Stefan S. Nicolau, Institute of Virology, Bucharest, Romania.; The pooling of five individual serum samples for the detection of human immunodeficiency virus type 1 (HIV-1) antibodies was examined to assess whether testing pooled versus individual sera was technically feasible. Detection of HIV-1 antibodies was performed using a competitive enzyme immunoassay (EIA) Wellcozyme HIV
Exercise intervention attenuates emotional distress and natural killer cell decrements following notification of positive serologic status for HIV-1.: Biofeedback Self Regul. 1990 Sep;15(3):229-42. Unique Identifier : AIDSLINE MED/91027946; LaPerriere AR; Antoni MH; Schneiderman N; Ironson G; Klimas N; Caralis P; Fletcher MA; Center for the Biopsychosocial Studies of AIDS, University of; Miami, Florida.; The impact of aerobic exercise training as a buffer of the affective distress and immune decrements which accompany the notification of HIV-1 antibody status in an AIDS risk group was studied. Fifty asymptomatic gay males with a pretraining fitness level of average or below (determined by predicted VO2 max) were rando
EPS, NMS, and AIDS [letter]: Biol Psychiatry. 1990 Sep 15;28(6):551-2. Unique Identifier : AIDSLINE MED/91028000; Lazarus A
Effects of membrane lipid and fluidity modifications on HIV-1 infectibility of primate lymphocytes in vitro.: Biosci Rep. 1990 Jun;10(3):263-70. Unique Identifier : AIDSLINE MED/91028157; Zimmer JP; Lehr HA; Hubner C; Lindner SG; Ramsperger R; Claussen M; Kohlschutter A; Schmitz H; Department of Virology, Bernhard Nocht Institute for Nautical and; Tropical Diseases, Hamburg, West Germany.; Although most non-human primates, except the chimpanzee and the gibbon in vivo are not infectible by HIV-1, lymphocytes of several of these species can be infected by HIV-1 in vitro. In order to investigate whether the in vitro infectibility of primate lymphocytes might be attributed to plasma membrane adaptation proc
Being positive: drug injectors' experiences of HIV infection.: Br J Addict. 1990 Sep;85(9):1113-24. Unique Identifier : AIDSLINE MED/91028319; McKeganey N; Social Paediatric and Obstetric Research Unit, University of; Glasgow, Scotland, UK.; There is a growing concern within Britain, Europe and North America that injecting drug users may pose the greatest risk of transmitting HIV infection to the wider heterosexual non-drug injecting population. However, we know very little about the reactions of injecting drug users to the knowledge of being HIV positive
AIDS-related risk behaviour, polydrug use and temazepam.: Br J Addict. 1990 Sep;85(9):1125-32. Unique Identifier : AIDSLINE MED/91028320; Klee H; Faugier J; Hayes C; Boulton T; Morris J; Faculty of Community Studies, Manchester Polytechnic, UK.; In a study of AIDS-related risk behaviour among injecting drug users in the north west of England it was found that 90% were polydrug users, and 28% were using temazepam. A third of all polydrug users had regularly used more than three drugs in addition to their preferred drug in the previous year. Statistical analysi
ICAA Berlin [news]: Br J Addict. 1990 Sep;85(9):1208. Unique Identifier : AIDSLINE MED/91028329
UK: MRC AIDS research 1990 [news]: Br J Addict. 1990 Sep;85(9):1208-9. Unique Identifier : AIDSLINE MED/91028330
Justice versus equity for haemophiliacs with AIDS [editorial] [see comments]: BMJ. 1990 Oct 6;301(6755):776. Unique Identifier : AIDSLINE MED/91028397; Dyer C
European meeting on HIV testing [news]: BMJ. 1990 Oct 6;301(6755):778. Unique Identifier : AIDSLINE MED/91028398; Glynn AA
Getting an AIDS vaccine to the developing world [news]: BMJ. 1990 Oct 6;301(6755):778-9. Unique Identifier : AIDSLINE MED/91028399; Rhein R
Choice cuts for patients with AIDS? [letter; comment]: BMJ. 1990 Oct 6;301(6755):816. Unique Identifier : AIDSLINE MED/91028413; Goh BT; Forster GE
Interaction between fluconazole and rifampicin.: BMJ. 1990 Oct 6;301(6755):818. Unique Identifier : AIDSLINE MED/91028419; Coker RJ; Tomlinson DR; Parkin J; Harris JR; Pinching AJ; St Mary's Hospital, London.
Combating AIDS in the Caribbean: a coordinated subregional approach.: Bull Pan Am Health Organ. 1990;24(3):335-40. Unique Identifier : AIDSLINE MED/91028477; Narain JP; White FM; Kimball AM; Zessler L; Zacarias FR; PAHO/WHO, Caribbean Epidemiology Center (CAREC), Port of Spain,; Trindad.
Impact of AIDS on surgery [letter; comment]: Br J Surg. 1990 Oct;77(10):1194. Unique Identifier : AIDSLINE MED/91028664; MacSweeney S
Disease transmission and cardiopulmonary resuscitation. Emergency Cardiac Care Committee, Heart and Stroke Foundation of Canada.: Can Med Assoc J. 1990 Nov 15;143(10):1007-8. Unique Identifier : AIDSLINE MED/91028942
Women and HIV infection and AIDS in Canada: should we worry? [editorial] [see comments]: Can Med Assoc J. 1990 Dec 1;143(11):1171-3. Unique Identifier : AIDSLINE MED/91028972; Hankins CA
Zidovudine (Retrovir) update.: Can Med Assoc J. 1990 Dec 1;143(11):1177-85. Unique Identifier : AIDSLINE MED/91028974; Rachlis AR; Department of Medicine, Sunnybrook Health Science Centre,; Toronto, Ont.; Zidovudine ( AZT ) is the first antiretroviral agent to be licensed for the treatment of human immunodeficiency virus (HIV) infection. Since the initial placebo-controlled trial showing improved survival among patients with acquired immunodeficiency syn
An anonymous seroprevalence survey of HIV infection among pregnant women in British Columbia and the Yukon Territory [see comments]: Can Med Assoc J. 1990 Dec 1;143(11):1187-92. Unique Identifier : AIDSLINE MED/91028975; Schechter MT; Ballem PJ; Buskard NA; Le TN; Thompson M; Marion SA; O'Shaughnessy MV; Department of Health Care and Epidemiology, Faculty of Medicine,; University of British Columbia, Vancouver.; We performed an anonymous seroprevalence survey of human immunodeficiency virus (HIV) type 1 infection through HIV antibody testing of blood samples from 22,512 women aged 15 to 44 years receiving prenatal care in British Columbia and the Yukon Territory from Mar. 15 to Sept. 30, 1989. Of the samples six were confirme
Women focus of this year's World AIDS Day [news]: Can Med Assoc J. 1990 Dec 1;143(11):1212. Unique Identifier : AIDSLINE MED/91028979
Guides, manuals for dealing with AIDS in workplace now available [news]: Can Med Assoc J. 1990 Dec 1;143(11):1213. Unique Identifier : AIDSLINE MED/91028980
Role of physicians key in national AIDS strategy, Ottawa says.: Can Med Assoc J. 1990 Dec 1;143(11):1217, 1219. Unique Identifier : AIDSLINE MED/91028981; Liston BJ; Department of National Health and Welfare, Ottawa.
HIV antibody testing: CMA counselling guidelines [letter] [see comments]: Can Med Assoc J. 1990 Nov 1;143(9):827-8. Unique Identifier : AIDSLINE MED/91028986
Risk factors for HIV seropositivity among people consulting for HIV antibody testing [letter] [published erratum appears in Can Med Assoc J 1990 Dec 15;143(12):1291] [comment]: Can Med Assoc J. 1990 Nov 1;143(9):828-9. Unique Identifier : AIDSLINE MED/91028987; Lamothe F; Bruneau J; Soto J; Brabant M; Vincelette J; Fauvel M
HIV infection among Quebec women giving birth to live infants [see comments]: Can Med Assoc J. 1990 Nov 1;143(9):885-93. Unique Identifier : AIDSLINE MED/91028999; Hankins CA; Laberge C; Lapointe N; Lai Tung MT; Racine L; O'Shaughnessy M; Centre d'etudes sur le SIDA, Departement de sante; communautaire, hopital general de Montreal.; This is the first anonymous unlinked seroprevalence study in Canada to use serum samples from newborns to determine the seroprevalence rate of human immunodeficiency virus (HIV) infection among childbearing women. Of the 68,808 samples tested 42 were confirmed as positive, for an o
Canadian lab to produce HIV immunogen for clinical trials [news]: Can Med Assoc J. 1990 Nov 1;143(9):907. Unique Identifier : AIDSLINE MED/91029003
Stand-alone HIV clinic expected to save money, help patients.: Can Med Assoc J. 1990 Nov 1;143(9):932-3. Unique Identifier : AIDSLINE MED/91029010; Johnston C
Perinatal infection of human T-lymphotropic virus type I, the etiologic virus of adult T-cell leukemia/lymphoma. DNA amplification of specific human T-lymphotropic virus type I sequences.: Cancer. 1990 Nov 1;66(9):1933-7. Unique Identifier : AIDSLINE MED/91029100; Saji F; Ohashi K; Tokugawa Y; Kamiura S; Azuma C; Tanizawa O; Department of Obstetrics and Gynecology, Osaka University Medical; School, Japan.; A gene amplification technique, polymerase chain reaction, was used to detect human T-lymphotropic virus type I (HTLV-I), the etiologic agent of adult T-cell leukemia/lymphoma, in mononuclear cells in peripheral blood and breast milk of ten HTLV-I carrier gravida. The DNA in umbilical cord blood mononuclear cells of t
Common ground [letter]: Can Nurse. 1990 Nov;86(10):10. Unique Identifier : AIDSLINE MED/91029121; Brouwer P
Fighting AIDS abroad [news]: Can Nurse. 1990 Oct;86(9):10. Unique Identifier : AIDSLINE MED/91029132; Remkes T
Caring for patients with AIDS.: Can Nurse. 1990 Oct;86(9):14. Unique Identifier : AIDSLINE MED/91029133; Pickthall L
Pathoepidemiological features of adult T-cell lymphoma/leukemia in an endemic area: Kagoshima, Japan.: Cancer Detect Prev. 1990;14(4):423-9. Unique Identifier : AIDSLINE MED/91029264; Sato E; Tokunaga M; Hasui K; Kitajima S; Nomoto M; Department of Pathology, Faculty of Medicine, Kagoshima; University, Japan.; In order to elucidate the pathological and epidemiological features of malignant lymphoma (ML), particularly of adult T-cell lymphoma/leukemia (ATLL) in the Kagoshima district, age-adjusted and age-specific incidence rates of malignant lymphomas were estimated on 3239 histologically confirmed cases between the years 1
Detection of preleukemic state of adult T-cell leukemia (pre-ATL) in HTLV-1 carriers.: Cancer Detect Prev. 1990;14(4):431-5. Unique Identifier : AIDSLINE MED/91029265; Ikeda S; Momita S; Amagasaki T; Tsukasaki K; Yamada Y; Kusumoto Y; Ito M; Kanda N; Tomonaga M; Soda H; et al; Department of Internal Medicine, Nagasaki University School of; Medicine, Japan.; The prevalence of the preleukemic state of adult T-cell leukemia (pre-ATL) was studied in Nagasaki prefecture, one of the endemic human T-lymphotropic virus type 1 (HTLV-1) areas in Japan . Pre-ATL cases have the monoclonal proliferation of abnormal lymphocytes, without signs of mali
Viral oncogenesis and the immune system.: Cancer Detect Prev. 1990;14(4):437-44. Unique Identifier : AIDSLINE MED/91029266; Rapp F; Cory JM; Department of Microbiology and Immunology, Pennsylvania State; University, College of Medicine, Hershey 17033.; Oncogenic transformation of normal cells and the establishment of transformed cells to form malignant tumors is a complex, multistep process influenced by viruses in multiple ways. The relationship between viruses and the immune system manifests itself, in part, through various roles of viruses in transformation of ho
[Establishment and application of serologic diagnosis method in human immunodeficiency virus]: Chung Hua Liu Hsing Ping Hsueh Tsa Chih. 1990 Aug;11(4):243-6. Unique Identifier : AIDSLINE MED/91029413; Wang Z; Zeng Y; Institute of Virology, Chinese Academy Preventive Medicine,; Beijing.; Using immunoenzymatic method (IE) for human immunodeficiency virus type 1 (HIV-1) serologic detection, and comparing with indirect immunofluorescence method (IIF). This method had same specificity and reproducibility but more sensitivity than IIF. Because it is simple, practical and suitable, IE method can replace IIF
Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication.: Cell. 1990 Nov 2;63(3):601-8. Unique Identifier : AIDSLINE MED/91029491; Sullenger BA; Gallardo HF; Ungers GE; Gilboa E; Program of Molecular Biology, Memorial Sloan-Kettering Cancer; Center, New York, New York 10021.; Overexpression of TAR-containing sequences (TAR decoys) was used to render cells resistant to HIV replication. A chimeric tRNA(meti)-TAR transcription unit contained in a double copy murine retroviral vector was used to express high levels of HIV-1 TAR-containing transcripts in CEM SS cells. Replication of HIV-1 was i
The HIV-1 Tat protein: an RNA sequence-specific processivity factor?: Cell. 1990 Nov 16;63(4):655-7. Unique Identifier : AIDSLINE MED/91029496; Cullen BR; Howard Hughes Medical Institute, Duke University Medical Center,; Durham, North Carolina 27710.
The hepatitis B virus-encoded transcriptional trans-activator hbx appears to be a novel protein serine/threonine kinase [published erratum appears in Cell 1993 Nov 19;75(4):826]: Cell. 1990 Nov 16;63(4):687-95. Unique Identifier : AIDSLINE MED/91029500; Wu JY; Zhou ZY; Judd A; Cartwright CA; Robinson WS; Department of Medicine, Stanford University School of Medicine,; California 94305.; To study the functional mechanism of the hepatitis B virus (HBV) X (hbx) gene product, we have expressed the hbx protein in E. coli and purified it by HPLC. The purified hbx protein was shown to be active in transactivating transcription directed by the LTR sequence of HIV-1. The hbx protein was found to have an intri
HIV-1 Tat protein trans-activates transcription in vitro.: Cell. 1990 Nov 16;63(4):791-802. Unique Identifier : AIDSLINE MED/91029510; Marciniak RA; Calnan BJ; Frankel AD; Sharp PA; Center for Cancer Research, Massachusetts Institute of; Technology, Cambridge 02139.; Tat protein of human immunodeficiency virus 1 is a potent trans-activator of viral gene expression. We show that purified Tat protein stimulates transcription from viral promoters greater than 10-fold in vitro. A Tat protein mutant that does not trans-activate in vivo did not stimulate transcription in vitro. Tat tran
The v-rel oncogene encodes a kappa B enhancer binding protein that inhibits NF-kappa B function.: Cell. 1990 Nov 16;63(4):803-14. Unique Identifier : AIDSLINE MED/91029511; Ballard DW; Walker WH; Doerre S; Sista P; Molitor JA; Dixon EP; Peffer NJ; Hannink M; Greene WC; Howard Hughes Medical Institute, Duke University Medical Center,; Durham, North Carolina 27710.; Studies of NF-kappa B suggest that this enhancer binding activity corresponds to a family of at least four proteins (p50, p55, p75, and p85) differentially induced with biphasic kinetics during T cell activation. While p55 and p50 are closely related to the 50 kd DNA binding subunit of NF-kappa B, p75 and p85 exhibit
[Problems in artificial insemination and the activity of sperm banks]: Cesk Gynekol. 1990 Sep;55(8):626-9. Unique Identifier : AIDSLINE MED/91029597; Vrabec J; Stencl J; Hruzik P; Urolog. klinika LFKU, Bratislava.
HTLV-I viral-associated myelopathy after blood transfusion in a multiple trauma patient.: Clin Orthop. 1990 Nov;(260):191-4. Unique Identifier : AIDSLINE MED/91030233; Delamarter RB; Carr J; Saxton EH; Division of Orthopaedic Surgery, UCLA School of Medicine 90024.; This may be the first documented case in the United States and in the orthopedic literature of transfusion-transmitted human T-cell leukemia virus Type I (HTLV-I)-associated myelopathy (HAM). Progressive myelopathy occurred in a 58-year-old white man with serologic and molecular eviden
High resolution computed tomography of Pneumocystis carinii pneumonia in AIDS [see comments]: Clin Radiol. 1990 Oct;42(4):239-43. Unique Identifier : AIDSLINE MED/91030377; Moskovic E; Miller R; Pearson M; Department of Radiology, Brompton Hospital, London.; High resolution computed tomography (CT) was performed on 11 homosexual men with the Acquired Immune Deficiency Syndrome (AIDS). All had bronchoscopically proven Pneumocystis carinii pneumonia (PCP). Six patients were re-scanned following treatment and symptomatic recovery. All the scans were abnormal, most showing fi
Acquired immunodeficiency syndrome and critical care [editorial] [see comments]: Crit Care Med. 1990 Nov;18(11):1300-2. Unique Identifier : AIDSLINE MED/91030657; Sprung CL; Steinberg A
ANA policies regarding HIV disease [news]: Crit Care Nurse. 1990 Oct;10(9):57, 85, 97. Unique Identifier : AIDSLINE MED/91030671
People and environment protected from medical sharps with new disposal system [news]: Crit Care Nurse. 1990 Oct;10(9):84. Unique Identifier : AIDSLINE MED/91030677
Recent developments in sexually transmitted diseases: is heterosexual transmission of human immunodeficiency virus a major epidemiologic factor in the spread of acquired immunodeficiency syndrome? III: AIDS in Sub-Saharan Africa.: Cutis. 1990 Sep;46(3):204-6. Unique Identifier : AIDSLINE MED/91030684; Felman YM; Downstate Medical School, Brooklyn, New York.
Tuberculosis in the time of AIDS. The facts and the message [editorial; comment]: Chest. 1990 Nov;98(5):1051-2. Unique Identifier : AIDSLINE MED/91030703; Ellner JJ
Undiagnosed tuberculosis in patients with human immunodeficiency virus infection [see comments]: Chest. 1990 Nov;98(5):1056-9. Unique Identifier : AIDSLINE MED/91030707; Flora GS; Modilevsky T; Antoniskis D; Barnes PF; Department of Medicine, Los Angeles County-University of Southern; California Medical Center.; We describe the clinical features of 11 patients with human immunodeficiency virus infection in whom tuberculosis was undiagnosed and untreated prior to death. Most patients (9 of 11) had pulmonary complaints and 8 of 11 had roentgenographic findings suggestive of tuberculosis (hilar or mediastinal adenopathy, pleural
Pulmonary manifestations of disseminated cryptococcosis in patients with AIDS.: Chest. 1990 Nov;98(5):1060-6. Unique Identifier : AIDSLINE MED/91030708; Chechani V; Kamholz SL; Department of Medicine, State University of New York Health; Science Center, Brooklyn.; Forty-eight patients with disseminated cryptococcosis and AIDS were retrospectively studied to define the pulmonary manifestations. Cryptococcus neoformans (CN) was first isolated from a pulmonary site in 12 patients. Disseminated disease was subsequently documented in all these patients. Symptoms and roentgenographic
Use of Nd:YAG laser in endobronchial Kaposi's sarcoma.: Chest. 1990 Nov;98(5):1299-300. Unique Identifier : AIDSLINE MED/91030761; Nathan S; Vaghaiwalla R; Mohsenifar Z; Department of Medicine, Cedars-Sinai Medical Center, UCLA School; of Medicine 90048.; An unusual case of endobronchial Kaposi s sarcoma causing right middle and lower lobe atelectasis is reported. The lesion was successfully removed with Nd-YAG laser photoresection.
[Inhibition of the reproduction of the human immunodeficiency virus in a cell culture with antisense oligonucleotide derivatives]: Dokl Akad Nauk SSSR. 1990;312(5):1259-62. Unique Identifier : AIDSLINE MED/91030954; Abramova TV; Blinov VM; Vlasov VV; Gorn VV; Zarytova VF; Ivanova EM; Konevets DA; Pliasunova OA; Pokrovskii AG; Sandakhchiev LS; et al
[Pneumocystis carinii pneumonia in HIV infection: better prognosis because of early diagnosis]: Dtsch Med Wochenschr. 1990 Oct 26;115(43):1619-23. Unique Identifier : AIDSLINE MED/91031004; Weber R; Opravil M; Bloch K; Speich R; Linnenberg HS; Kuster H; Kagi M; Jacquier P; Eckert J; Russi EW; et al; Departement fur Innere Medizin, Universitatsspital, Zurich.; The clinical presentation of 60 consecutive Pneumocystis carinii pneumonias in 58 HIV-infected patients (48 men, 10 women, mean age 34 [22-53] years) was prospectively evaluated from April to August 1989 and compared with 60 consecutive P. carinii pneumonias in 59 HIV-infected patients (55 men, 4 women, mean age 37.5
[Extraintestinal strongyloidiasis in the acquired immunodeficiency syndrome]: Dtsch Med Wochenschr. 1990 Nov 9;115(45):1716-9. Unique Identifier : AIDSLINE MED/91031027; Stey C; Jost J; Luthy R; Abteilung fur Infektionskrankheiten, Universitatsspital; Zurich.; A 41-year old man of Brazilian origin, suffering from AIDS for one year, fell ill with pyrexia of over 39 degrees C, dyspnoea, chest pain and deterioration in his general condition. At the same time he noted a discrete skin eruption, mainly on the upper limbs. Diarrhoea began later. A chest radiograph revealed bilater
Sexually transmitted diseases and HIV-1: interactions in transmission and role in control programs [editorial]: East Afr Med J. 1990 Jul;67(7):457-60. Unique Identifier : AIDSLINE MED/91031111; Plummer FA; Ndinya-Achola JO
Prevalence of antibodies to human T-lymphotropic virus type 1 (HTLV-1) in an HIV-endemic region of Africa.: East Afr Med J. 1990 Jul;67(7):461-5. Unique Identifier : AIDSLINE MED/91031112; Maselle SY; Shao JF; Haukenes G; Department of Microbiology and Immunology, Muhimbili Medical; Centre, University of Dar es Salaam, Tanzania.; Serum samples from 267 healthy subjects and patients either infected or not infected with HIV-1 in Dar es Salaam, Tanzania , were examined by enzyme-linked immunosorbent assay and western blot techniques for evidence of HTLV-1 infection. Specific antibodies were detected in only 1
HIV infection surveillance in Mogadishu, Somalia.: East Afr Med J. 1990 Jul;67(7):466-72. Unique Identifier : AIDSLINE MED/91031113; Burans JP; Fox E; Omar MA; Farah AH; Abbass S; Yusef S; Guled A; Mansour M; Abu-Elyazeed R; Woody JN; US Naval Medical Research Unit No. 3, Cairo, Egypt.; A group of 89 prostitutes and 45 patients attending sexually transmitted disease clinics in Mogadishu, Somalia were examined for evidence of HIV infection. Both groups reported more than 1 sexual partner routinely and had sexual contacts with prostitutes. There was a significant a
Inter-relationships between HIV infection and other sexually transmitted diseases.: East Afr Med J. 1990 Jul;67(7):512-7. Unique Identifier : AIDSLINE MED/91031120; Mhalu FS; Department of Microbiology and Immunology, Muhimbili Medical; Centre, Dar es Salaam, Tanzania.; The HIV is a typical sexually transmitted disease (STD) agent which depends for its transmission through sex on contact between raw body tissues of infected and uninfected individuals independent of sexual inclination. The dynamics of HIV transmission and its control in a community can be inferred from studying the so
Conjunctival Kaposi's sarcoma in a patient with acquired immune deficiency syndrome.: East Afr Med J. 1990 Jul;67(7):518-21. Unique Identifier : AIDSLINE MED/91031121; Awan HR; Adala HS; Bahador FA; Department of Surgery, University of Nairobi.; A patient with confirmed acquired immune deficiency syndrome (AIDS) and disseminated Kaposi s sarcoma was seen in the Eye Clinic, Kenyatta National Hospital, and was found to have involvement of the conjunctiva and lids, confirmed by biopsy. He also had retinal haemorrhages and cotton-wool spots. Kaposi s sarcoma of t
Herpes Zoster Ophthalmicus in a child with acquired immune deficiency syndrome.: East Afr Med J. 1990 Jul;67(7):522-6. Unique Identifier : AIDSLINE MED/91031122; Awan HR; Adala HS; Department of Surgery, College of Health Sciences, University of; Nairobi.; A case is described of an 8 year old child who presented with Herpes Zoster Ophthalmicus involving the left eye. He had a positive history of pulmonary tuberculosis, repeated hospital admissions and blood transfusion. He was confirmed to have Acquired Immune Deficiency Syndrome. During the course of his followup, he d
The history of interferon and its use in animal therapy.: East Afr Med J. 1990 Jul;67(7 Suppl 2):SS31-63. Unique Identifier : AIDSLINE MED/91031124; Young AS; Cummins JM; Overseas Development Administration of U.K.; The history of the discovery and development of knowledge on interferon is reviewed in some depth. Although interferons have been considered a very exciting group of proteins for many years during which they were initially shown to have antiviral effects and lately immunomodulatory and immunoregulatory effects, attemp
Efficacy of Kemron (low dose oral natural human interferon alpha) in the management of HIV-1 infection and acquired immune deficiency syndrome (AIDS).: East Afr Med J. 1990 Jul;67(7 Suppl 2):SS64-70. Unique Identifier : AIDSLINE MED/91031125; Koech DK; Obel AO; Kenya Medical Research Institute, Nairobi.; One hundred and ninety nine symptomatic and 5 asymptomatic patients seropositive for the human immunodeficiency virus type 1 (HIV-1) were treated with KEMRON, a natural human interferon alpha (nHIF alpha) stabilized in a complex polysacchariche carrier. Treatment was given for at least 10 weeks at a daily oral dose of
Treatment of HIV infections and AIDS: new horizons.: East Afr Med J. 1990 Jul;67(7 Suppl 2):SS77-81. Unique Identifier : AIDSLINE MED/91031127; Koech DK; Obel AO; Kenya Medical Research Institute.; Treatment of HIV infections has involved the use of antiviral drugs as well as those drugs that act against opportunistic infections. Immune modulators have also been used. A review of these drugs is reported emphasizing on those which have great promise in the clinical management of HIV infections in the light of our
Kemron. Low dose natural human interferon alpha for oral administration (general information and technical details).: East Afr Med J. 1990 Jul;67(7 Suppl 2):SS82-6. Unique Identifier : AIDSLINE MED/91031128
Screening for new agents.: Eur J Clin Microbiol Infect Dis. 1990 Jul;9(7):466-71. Unique Identifier : AIDSLINE MED/91031512; Oberg B; Vrang L; Department of Virology, Karolinska Institute, Stockholm, Sweden.; Screening for new antiviral drugs is concentrated on a search for inhibitors of the human immunodeficiency virus, herpesviruses, influenza virus, hepatitis B virus and rhinovirus. The first step in the process is usually the screening of virus-infected cell cultures followed by secondary screening in infected animals.
Evaluation of a line immunoassay for the differential detection of antibodies to human immunodeficiency virus.: Eur J Clin Microbiol Infect Dis. 1990 Sep;9(9):674-6. Unique Identifier : AIDSLINE MED/91031537; Vranckx R; Institute of Hygiene and Epidemiology, Brussels, Belgium.; A newly introduced single strip line immunoassay was evaluated as a possible alternative to Western blot for the differential detection of antibodies to multiple HIV-1 and HIV-2 antigens in human serum. In a panel of 153 sera found to be positive twice in currently used screening tests, the line immunoassay and the We
Reactivation of hepatitis B virus in a previously immune patient with human immunodeficiency virus infection [letter]: Eur J Clin Microbiol Infect Dis. 1990 Sep;9(9):701-2. Unique Identifier : AIDSLINE MED/91031544; Vandercam B; Cornu C; Gala JL; Geubel A; Cahill M; Lamy ME
Transfontanellar ultrasonography in HIV-positive children [letter]: Eur J Pediatr. 1990 Aug;149(11):810. Unique Identifier : AIDSLINE MED/91031620; Giovannini M; Zuccotti GV; Bossi MC; Riva E
HIV therapy update.: Fla Nurse. 1990 Oct;38(9):20. Unique Identifier : AIDSLINE MED/91032398; Marchette L
[Commentary on the new AIDS guideline and on the 4th regulation of implementation]: Dermatol Monatsschr. 1990;176(5-6):390-1. Unique Identifier : AIDSLINE MED/91032485; Kolzsch J; Sonnichsen N
Influence of pregnancy on human immunodeficiency virus disease.: Eur J Obstet Gynecol Reprod Biol. 1990 Dec;37(3):211-7. Unique Identifier : AIDSLINE MED/91032497; Berrebi A; Kobuch WE; Puel J; Tricoire J; Herne P; Grandjean H; Pontonnier G; Services de Gynecologie-Obstetrique, CHU La Grave, Toulouse,; France.; Over a period of 3 years (mean 16, extremes 3 and 36 months), we compared clinical and laboratory parameters of 128 female, human immunodeficiency virus (HIV)-infected patients, all in clinical stage II or III (CDC classification). 34 patients were pregnant and delivered a viable infant after at least 28 weeks of amen
Isolation of zidovudine resistant Escherichia coli from AIDS patients.: FEMS Microbiol Lett. 1990 Jul;58(2):141-3. Unique Identifier : AIDSLINE MED/91032876; Lewin CS; Watt B; Paton R; Amyes SG; Bacteriology Department, University Medical School, Edinburgh,; U.K.; Zidovudine-resistant Escherichia coli were isolated from faecal samples from 6 out of 11 AIDS patients receiving zidovudine. Resistance appeared to be due to the loss of thymidine kinase activity which is required for the phosphorylation of zidovudine to its active form. No zidovudine resistant enterobacteria were iso
Interaction of the human immunodeficiency virus type 1 Rev protein with a structured region in env mRNA is dependent on multimer formation mediated through a basic stretch of amino acids.: Genes Dev. 1990 Aug;4(8):1357-64. Unique Identifier : AIDSLINE MED/91032987; Olsen HS; Cochrane AW; Dillon PJ; Nalin CM; Rosen CA; Department of Molecular Oncology and Virology, Roche Institute of; Molecular Biology, Nutley, New Jersey.; Interaction of the human immunodeficiency virus type 1 (HIV-1) Rev protein with a structured region within env mRNA (termed RRE) mediates the export of virus structural mRNAs from the nucleus to the cytoplasm. We show that the region encompassing the basic stretch of amino acids is essential for the ability of Rev to
A bulge structure in HIV-1 TAR RNA is required for Tat binding and Tat-mediated trans-activation.: Genes Dev. 1990 Aug;4(8):1365-73. Unique Identifier : AIDSLINE MED/91032988; Roy S; Delling U; Chen CH; Rosen CA; Sonenberg N; Department of Biochemistry, McGill University, Montreal, Quebec,; Canada.; The Tat protein of human immunodeficiency virus type 1 (HIV-1) trans-activates viral gene expression and is obligatory for virus replication. Tat function is mediated through a sequence termed TAR that comprises part of the 5 -noncoding region of all HIV-1 mRNAs. This region forms a stable stem-loop structure in vitro
Human immunodeficiency virus infection and cervical neoplasia.: Gynecol Oncol. 1990 Sep;38(3):377-82. Unique Identifier : AIDSLINE MED/91033204; Maiman M; Fruchter RG; Serur E; Remy JC; Feuer G; Boyce J; Department of Obstetrics and Gynecology, State University of New; York-Health Science Center, Brooklyn 11203.; To determine the relationship between human immunodeficiency virus (HIV) infection and cervical neoplasia, the characteristics of invasive and preinvasive cervical disease in 114 patients of known HIV status were assessed. Seven of thirty-seven patients (19%) under age 50 with invasive cervical carcinoma were HIV-posi
Perinatal outcome in HIV-infected pregnant women.: Gynecol Obstet Invest. 1990;30(1):15-8. Unique Identifier : AIDSLINE MED/91033276; Semprini AE; Ravizza M; Bucceri A; Vucetich A; Pardi G; Department of Obstetrics and Gynecology, University of Milano; Medical School, Ospedale S. Paolo, Italy.; We have observed 74 HIV-seropositive and 48 HIV-seronegative drug-addicted women and 22 HIV-seropositive nondrug-addicted pregnant women during pregnancy and we report their perinatal outcome. 8 out of 96 HIV-seropositive patients had hematological signs of immunodeficiency and 2 of these patients were symptomatic bel
High expression of multinucleated giant cells in cultures of peripheral blood cells from HIV infected patients.: Haematologica. 1990 May-Jun;75(3):212-9. Unique Identifier : AIDSLINE MED/91033292; Bigi G; Stone G; Cerri A; Sun D; Sarin PS; Instituto di Medicina Interna e Fisiopatologia Medica,; Universita, Facolta di Medicina e Chirugia, Milano, Italy.; Multinucleated giant cells (MGCs) were detected in cell lines established from peripheral blood lymphocytes of patients with: (a) acquired immunodeficiency syndrome (AIDS) and lymphadenopathy syndrome (LAS), (b) chronic active hepatitis (CAH), (c) papular acrodermatitis (PA) negative for hepatitis B virus antigens but
Incidence and clinicopathological heterogeneity of HIV-related non-Hodgkin's lymphoma.: Haematologica. 1990 May-Jun;75(3):235-42. Unique Identifier : AIDSLINE MED/91033296; Rossi G; Cadeo G; Stellini R; Zorzi F; Favret M; Sueri L; Carosi G; Mariano M; Marinone G; III Divisione Medicina Generale, Spedali Civili, Brescia, Italy.; The characteristics of 14 HIV-seropositive patients with NHL consecutively observed between 1984 and 1988 at our Institution are described. Patients belonged to a known population of 1242 HIV-seropositive individuals in whom the incidence of NHL was 1.13%, significantly higher than in age-matched controls (P less than
Bone marrow transplantation in an HIV positive thalassemic child following therapy with azidothymidine.: Haematologica. 1990 May-Jun;75(3):285-7. Unique Identifier : AIDSLINE MED/91033306; Angelucci E; Lucarelli G; Baronciani D; Durazzi SM; Galimberti M; Maddaloni D; Polchi P; Divisione di Ematologia, Ospedale di Pesaro, Italy.; The authors report their experience on allogeneic bone marrow transplant in an HIV seropositive thalassemic child. Before transplant a treatment with Azidothymidine was performed with the aim of reducing the viral load. Engraftment took place but, later, an explosive upsurge of viral disease occurred with encephalitis
[Acquired immunodeficiency]: Fortschr Med. 1990 Sep 20;108(27):511-3. Unique Identifier : AIDSLINE MED/91033482; Kreth HW; Kinderklinik Universitat Wurzburg.; Secondary immunodeficiencies are much more frequent than primary immunological disorders. There are many etiologies, such as malnutrition, cytostatic drug therapy, burns, protein-losing conditions and infections. This review briefly considers the history of virus-induced immunosuppression. Today, measles and AIDS are
Drug approval and AIDS: benefits for the elderly.: Health Aff (Millwood). 1990 Fall;9(3):123-30. Unique Identifier : AIDSLINE MED/91033523; Rothman DJ; Edgar H; Center for the Study of Society and Medicine, College of; Physicians and Surgeons of Columbia University, New York City.
Media consultation on AIDS [news]: Hygie. 1990 Sep;9(3):43. Unique Identifier : AIDSLINE MED/91033828; Parthasarathy TK
An immunodominant antigen of Candida albicans shows homology to the enzyme enolase [published erratum appears in Immunol Cell Biol 1990 Oct;68(Pt 5):347]: Immunol Cell Biol. 1990 Jun;68 ( Pt 3):173-8. Unique Identifier : AIDSLINE MED/91033917; Franklyn KM; Warmington JR; Ott AK; Ashman RB; Department of Medical Technology, Curtin University of; Technology, Bentley, WA 6102.; Antibody to an immunodominant antigen of approximately 48 kDa is found in a high proportion of patients with mucocutaneous or systemic infections of the yeast Candida albicans. A cDNA encoding part of the 48 kDa antigen has been isolated. From the deduced amino acid sequence of the cDNA clone, the 48 kDa antigen shows
[Blood deficiency values of polyunsaturated fatty acids of phospholipids, vitamin E and glutathione peroxidase as possible risk factors in the onset and development of acquired immunodeficiency syndrome]: G Ital Dermatol Venereol. 1990 Apr;125(4):125-30. Unique Identifier : AIDSLINE MED/91033926; Passi S; De Luca C; Picardo M; Morrone A; Ippolito F; Istituto Dermatologico Santa Maria e San Gallicano, Roma.; Plasma levels of vitamin E (vit E) and polyunsatured fatty acids of phospholipids (PUFA-PL) as well as erythrocyte glutathione peroxidase (GSH-Px) activity are significantly lower (p less than 0.001) in patients HIV sero-positive (AIDS and ARC cases) both affected and not affected with seborrheic dermatitis and in 32%
HIV seropositivity among patients with sexually transmitted diseases in Vellore.: Indian J Med Res. 1990 Jul;91:239-41. Unique Identifier : AIDSLINE MED/91033946; Mathai R; Prasad PV; Jacob M; Babu PG; John TJ; Department of Dermatology, Christian Medical College & Hospital,; Vellore.; In a prospective, systematic investigation, 2215 new patients with sexually transmitted diseases (STD) were screened for human immuno deficiency virus (HIV) infection during April 1986 to December 1988. Among them 9 were positive for HIV antibody giving a rate of 4/1000. In addition, 5 patients had been referred to ou
Human milk banking: current concepts.: Indian J Pediatr. 1990 May-Jun;57(3):361-74. Unique Identifier : AIDSLINE MED/91033993; Mehta NR; Subramanian KN; Department of Pediatrics, Georgetown University School of; Medicine, Washington, D.C.
Reduced lymphocyte responses to mitogens in natural and experimental trichomoniasis.: Infect Immun. 1990 Nov;58(11):3553-7. Unique Identifier : AIDSLINE MED/91034163; Mason PR; Gwanzura L; Department of Medical Microbiology, University of Zimbabwe; Medical School, Harare.; Proliferative responses to mitogens were determined by using peripheral blood mononuclear cells from women with active trichomoniasis, with serological evidence of past infection with Trichomonas vaginalis, and with no evidence of current or past infection. Even after the human immunodeficiency virus antibody status o
Transfusion risks.: Int Anesthesiol Clin. 1990 Fall;28(4):184-9. Unique Identifier : AIDSLINE MED/91034223; Faust RJ; Warner MA; Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905.; Hepatitis remains the most serious transfusion risk, in terms of incidence and severity. Transfusion-associated AIDS, hemolytic reactions, TRALI, and anaphylaxis are severe problems that occur relatively rarely, while febrile reactions and mild allergic reactions are common but not serious. The key to avoiding all the
AIDS-related risk behaviors among substance abusers.: Int J Addict. 1990 Mar;25(3):291-9. Unique Identifier : AIDSLINE MED/91034304; Ottomanelli G; Kramer TH; Bihari B; Fine J; Heller S; Mosely JA; State University of New York, Health Sciences Center, Brooklyn; 11203.; Ninety-two substance abusers were surveyed about AIDS-related risk behaviors. The questionnaire administered elicited information on demographics, sexual practices, substance abuse, and risk behaviors involving the use of needles. Results indicated an appropriate base of prevention knowledge and patients efforts to m
Lung pathology in HIV positive patients.: Ir Med J. 1990 Sep;83(3):109-11. Unique Identifier : AIDSLINE MED/91034612; McLoughlin P; Mulcahy F; O'Briain DS; Kane B; Mulvihill E; Prichard JS; Department of Medicine, Trinity College Dublin.; We describe the results of 43 bronchoscopic examinations carried out on 35 patients who were HIV positive. Of these, 13 were intravenous drug abusers, 13 were homosexual or bisexual, six were haemophiliacs, two were homosexual intravenous drug abusers and one was a heterosexual contact of a drug abuser. All underwent
The Ugandan AIDS epidemic--a personal comment [editorial]: Ir Med J. 1990 Sep;83(3):89. Unique Identifier : AIDSLINE MED/91034623; Kellett J
Noncompliance in AIDS research.: Hastings Cent Rep. 1990 Sep-Oct;20(5):24-32. Unique Identifier : AIDSLINE MED/91034675; Arras JD; Montefiore Medical Center, Albert Einstein College of Medicine,; New York, NY.; Participants in AIDS research may justify non-compliance with protocols by a coercion defense. While this defense may not be philosophically successful, a prudent social policy can enhance compliance by encouraging community participation and providing greater access to non-validated therapies.
Chronic encephalitis caused by leukoencephalopathy.: Heart Lung. 1990 Nov;19(6):678-84. Unique Identifier : AIDSLINE MED/91034766; Ast D; Cunha BA; Infectious Disease Division, Winthrop-University Hospital,; Mineola, NY 11501.; As mentioned previously, both MS and PML are demyelinating conditions of the CNS and pose diagnostic difficulties in their differentiation because of similarities in their clinical findings. However, certain features unique to each of these diseases are helpful in clinical diagnosis. MS, unlike PML, is a disease of un
Systemic dissemination of Pneumocystis carinii in a patient with acquired immunodeficiency syndrome.: Henry Ford Hosp Med J. 1990;38(1):68-71. Unique Identifier : AIDSLINE MED/91034854; Amin MB; Abrash MP; Mezger E; Sekerak GF; Department of Pathology, Henry Ford Hospital, Detroit, MI 48202.; Pneumocystis carinii is usually considered a respiratory tract pathogen; however, there are reported cases of limited and generalized dissemination of the organism from the lungs of immunocompromised patients. We present the autopsy findings of a 29-year-old male with acquired immunodeficiency syndrome (AIDS) and recu
Expression of human immunodeficiency virus 1 (HIV-1) envelope gene products transcribed from a heterologous promoter. Kinetics of HIV-1 envelope processing in transfected cells.: J Biol Chem. 1990 Nov 5;265(31):19151-7. Unique Identifier : AIDSLINE MED/91035446; Bird C; Burke J; Gleeson PA; McCluskey J; Department of Pathology and Immunology, Monash Medical School,; Monash University, Melbourne, Victoria, Australia.; The expression of human immunodeficiency virus 1 (HIV-1) envelope glycoprotein products was studied in cells transfected with env gene constructs transcribed from an SV40 promoter. Gene constructs possessing the complete tat, rev (tat+ rev+) and env genes were transiently expressed in COS-1 cells as precursor SU-TM (g
Thyroiditis as the presenting manifestation of disseminated extrapulmonary Pneumocystis carinii infection.: J Clin Endocrinol Metab. 1990 Dec;71(6):1663-5. Unique Identifier : AIDSLINE MED/91035895; Drucker DJ; Bailey D; Rotstein L; Department of Medicine, Toronto General Hospital, University of; Toronto, Ontario, Canada.; A 38-yr-old male with acquired immunodeficiency syndrome developed neck pain in association with mild hyperthyroidism and a diffusely enlarged thyroid gland. Radioactive iodine scanning was consistent with thyroiditis, and biopsy of the thyroid demonstrated the presence of pneumocystis carinii in thyroid tissue. Treat
Beta 2-microglobulin and neopterin: predictive markers for human immunodeficiency virus type 1 infection in children? [see comments]: J Clin Microbiol. 1990 Oct;28(10):2215-9. Unique Identifier : AIDSLINE MED/91035924; Chan MM; Campos JM; Josephs S; Rifai N; Department of Laboratory Medicine, Children's National Medical; Center, Washington, D.C. 20010.; The value of beta 2-microglobulin and neopterin concentrations in serum for early diagnosis of infants born to human immunodeficiency virus type 1 (HIV-1)-infected mothers was assessed. Concentrations of both markers were measured in serum samples from pediatric patients (Centers for Disease Control classifications P0
Importance of membrane-bound antigens of Toxoplasma gondii and their fixation for serodiagnosis of toxoplasmic encephalitis in patients with acquired immunodeficiency syndrome.: J Clin Microbiol. 1990 Oct;28(10):2354-6. Unique Identifier : AIDSLINE MED/91035951; Suzuki Y; Remington JS; Department of Parasitology, Jikei University School of Medicine,; Tokyo, Japan.; Titers in a direct agglutination test using Formalin-fixed toxoplasma tachyzoites were significantly higher in patients with acquired immunodeficiency syndrome with toxoplasmic encephalitis (TE) than in those without TE. In contrast, when fresh (not fixed) tachyzoites were used, the titers did not differ from those in
Campylobacter-like organisms are uncommon pathogens in patients infected with the human immunodeficiency virus.: J Clin Microbiol. 1990 Oct;28(10):2370-1. Unique Identifier : AIDSLINE MED/91035956; Wilcox CM; Byford BA; Forsmark CE; Hadley WK; Cello JP; Jacobson MA; Division of Gastroenterology, San Francisco General Hospital,; California 94110.; Over a 25-month period, we prospectively evaluated 36 patients with symptomatic human immunodeficiency virus disease (including 27 with unexplained chronic diarrhea) by flexible sigmoidoscopy for the presence of Campylobacter-like organisms. No Campylobacter-like organisms were isolated. Campylobacter-like organisms a
Comparison of immunofluorescence, particle agglutination, and enzyme immunoassays for detection of human T-cell leukemia virus type I antibody in African sera.: J Clin Microbiol. 1990 Sep;28(9):1988-93. Unique Identifier : AIDSLINE MED/91035983; Verdier M; Denis F; Leonard G; Sangare A; Patillaud S; Prince-David M; Essex M; Department of Bacteriology-Virology, Centre Hospitalier; Universitaire Dupuytren, Limoges, France.; The effectiveness of four screening tests for detecting antibody to human T-cell leukemia virus type I (HTLV-I) was determined by using 2,700 African serum specimens. The tests studied were indirect immunofluorescence, particle agglutination from Fujirebio, and two enzyme immunoassays, one from
Application of a rapid microplaque assay for determination of human immunodeficiency virus neutralizing antibody titers.: J Clin Microbiol. 1990 Sep;28(9):2030-4. Unique Identifier : AIDSLINE MED/91035990; Hanson CV; Crawford-Miksza L; Sheppard HW; Viral and Rickettsial Disease Laboratory, California Department; of Health Services, Berkeley 94704.; To perform a human immunodeficiency virus (HIV) plaque assay in nonadherent host cells, we developed a novel technique in which HIV-infected MT-2 cells were formed into monolayers by centrifugation through molten agarose. Infection, formation of cell monolayers, and enumeration of plaques all took place in 96-well mic
Immunoprecipitation of human immunodeficiency virus type 2 glycoproteins by sera positive for human immunodeficiency virus type 1.: J Clin Microbiol. 1990 Sep;28(9):2107-10. Unique Identifier : AIDSLINE MED/91036005; Espejo RT; Uribe P; Centro de Estudios Cientificos de Santiago, Chile.; Analysis by radioimmunoprecipitation of serum samples from 27 different human immunodeficiency virus type 1 (HIV-1)-infected individuals residing in Chile showed that the sera of 26% of these individuals also react with glycoprotein gp125 of HIV type 2 (HIV-2). This cross-reaction s
Bacillus species pseudobacteremia traced to contaminated gloves used in collection of blood from patients with acquired immunodeficiency syndrome.: J Clin Microbiol. 1990 Sep;28(9):2114-6. Unique Identifier : AIDSLINE MED/91036007; York MK; Department of Laboratory Medicine, University of California, San; Francisco 94143.; Ten nonpathogenic Bacillus isolates were obtained from blood cultures collected over a 2-year period. Eight of these isolates were from patient with acquired immunodeficiency syndrome, and seven were recovered from blood cultures obtained in outpatient clinics. Five cases occurred during a 5-month period. These five c
Quantitation of human immunodeficiency virus DNA by using the polymerase chain reaction.: J Clin Microbiol. 1990 Sep;28(9):2130-3. Unique Identifier : AIDSLINE MED/91036013; Dickover RE; Donovan RM; Goldstein E; Dandekar S; Bush CE; Carlson JR; Department of Internal Medicine, University of California, Davis; 95616.; The polymerase chain reaction was used to measure the DNA copy number of human immunodeficiency virus (HIV). Differences in polymerase chain reaction amplification efficiency were controlled by amplifying known amounts of HIV DNA in parallel with samples. This technique is a sensitive, accurate, and reproducible metho
Astrocyte-conditioned medium stimulates HIV-1 expression in a chronically infected promonocyte clone.: J Neuroimmunol. 1990 Dec;30(2-3):153-60. Unique Identifier : AIDSLINE MED/91036040; Vitkovic L; Kalebic T; de Cunha A; Fauci AS; Laboratory of Immunoregulation, National Institute of Allergy and; Infectious Diseases, National Institutes of Health, Bethesda, MD; 20892.; Human promonocytic cells chronically infected with human immunodeficiency virus-1 (HIV-1) (clone U1.1.5) were grown in the presence of media conditioned by primary rat cortical astrocytes and HIV-1 expression was assessed by measuring reverse transcriptase activity. Media conditioned by non-stimulated and lipopolysacc
Immunocytochemical analysis of lymph node aspirates in patients with human immunodeficiency virus infection.: J Clin Pathol. 1990 Oct;43(10):844-6. Unique Identifier : AIDSLINE MED/91036095; Oertel J; Oertel B; Lobeck H; Huhn D; Haematologische Abteilung, Freie Universitat Berlin, West; Germany.; Thirty four patients positive for human immunodeficiency virus (HIV) who had lymphadenopathy were investigated using fine needle aspiration. Cytological analysis included immunocytochemical investigation with the alkaline phosphatase-antialkaline phosphatase (APAAP) method. All patients had confirmation of cytological
Identification of human immunodeficiency virus hybridizing sequences in the peripheral blood of a patient with systemic lupus erythematosus.: J Am Acad Dermatol. 1990 Oct;23(4 Pt 1):641-5. Unique Identifier : AIDSLINE MED/91036173; Blick M; Bresser J; Lepe-Zuniga JL; Goodacre A; Luethke D; Holder WR; Duvic M; Department of Clinical Immunology and Biological Therapy,; University of Texas M. D. Anderson Cancer Center, Houston.; Systemic lupus erythematosus, a multisystemic disorder, is considered a prototype of the autoimmune diseases. Although its cause remains unknown, a viral etiology has been proposed. We report that a rapid and sensitive messenger RNA in situ hybridization technique detected hybridizing sequences to the human immunodefi
Cutaneous manifestations of postthymic T cell malignancies: description of five clinicopathologic subtypes.: J Am Acad Dermatol. 1990 Oct;23(4 Pt 1):653-62. Unique Identifier : AIDSLINE MED/91036176; Su IJ; Wu YC; Chen YC; Hsieh HC; Cheng AL; Wang CH; Kadin ME; Department of Pathology, National Taiwan University Hospital,; Taipei.; This study was undertaken to identify the cutaneous manifestations among different prognostic subgroups of postthymic T cell malignancies. Cutaneous involvement was demonstrated in 43 of 88 cases. We recognized five clinicopathologic subtypes: type I, classical cutaneous T cell lymphoma (CTCL) or mycosis fungoides, si
Miliary tuberculosis presenting as skin lesions in a patient with acquired immunodeficiency syndrome.: J Am Acad Dermatol. 1990 Nov;23(5 Pt 2):1031-5. Unique Identifier : AIDSLINE MED/91036234; Stack RJ; Bickley LK; Coppel IG; Department of Pathology, New Jersey Medical School, Newark.; Acute miliary tuberculosis of the skin is an extremely rare infection that occurs in immunocompromised persons. We report an intravenous drug abuser with human immunodeficiency virus infection in whom erythematous papules developed on the trunk and proximal aspect of the extremities. Visceral lesions of unsuspected mi
Disseminated Kaposi's sarcoma not associated with HIV infection in a bisexual man.: J Am Acad Dermatol. 1990 Nov;23(5 Pt 2):1035-8. Unique Identifier : AIDSLINE MED/91036235; Garcia-Muret MP; Pujol RM; Puig L; Moreno A; de Moragas JM; Department of Dermatology, Hospital de la Santa Creu i Sant Pau,; Barcelona, Spain.; We report a 42-year-old white bisexual man with disseminated Kaposi s sarcoma limited to the skin and gastrointestinal tract. Results of several serum tests for human immunodeficiency virus (HIV) antibodies have been negative. The CD4/CD8 ratio has remained normal, and his Kaposi s sarcoma has had a benign clinical co
Normal and abnormal white matter tracts shown by MR imaging using directional diffusion weighted sequences.: J Comput Assist Tomogr. 1990 Nov-Dec;14(6):865-73. Unique Identifier : AIDSLINE MED/91036261; Doran M; Hajnal JV; Van Bruggen N; King MD; Young IR; Bydder GM; Department of Diagnostic Radiology, Royal Postgraduate Medical; School, Hammersmith Hospital, London, England.; A pulsed magnetic field gradient spin echo technique was used to study the brain of two volunteers and eight patients. The pulsed gradients were applied both perpendicular and parallel to the image slice. Striking changes in signal intensity were demonstrated in white matter depending on the direction in which pulsed
Proton MR spectroscopy and imaging of the brain in AIDS: evidence of neuronal loss in regions that appear normal with imaging.: J Comput Assist Tomogr. 1990 Nov-Dec;14(6):882-5. Unique Identifier : AIDSLINE MED/91036263; Menon DK; Baudouin CJ; Tomlinson D; Hoyle C; Department of Diagnostic Radiology, Royal Postgraduate Medical; School, Hammersmith Hospital, London, U.K.; Central nervous system involvement is increasingly being recognised as a common manifestation of the acquired immunodeficiency syndrome (AIDS), either as a direct effect of the human immunodeficiency virus, or as a result of secondary infection or malignancy. A subset of patients with clinical or psychometric evidence
Modeling dental health care workers' risk of occupational infection from bloodborne pathogens.: J Dent Educ. 1990 Nov;54(11):687-8. Unique Identifier : AIDSLINE MED/91036333; Capilouto E; Weinstein MC; Orav EJ; Hemenway D; University of Alabama School of Dentistry, Birmingham 35294.
Kaposi's sarcoma: a light and electron microscopic study.: J Dermatol. 1990 Jul;17(7):414-22. Unique Identifier : AIDSLINE MED/91036353; Kato H; Hamada T; Tsuji T; Baba T; Seki J; Kobayashi Y; Department of Dermatology, Osaka City University Medical School,; Japan.; A patient with diabetes mellitus who developed the typical classic lesions of Kaposi s sarcoma is described. Our patient presented with a reddish-purple papulonodular lesion on the right foot of five months duration. A skin biopsy specimen showed a proliferation of spindle cells forming numerous vascular slits and a
Gay men's perceptions and responses to AIDS.: J Adv Nurs. 1990 Aug;15(8):895-905. Unique Identifier : AIDSLINE MED/91036402; Getty G; Stern P; Faculty of Nursing, University of New Brunswick, Fredericton.; Gay men continue to be the largest group in Canada developing AIDS. They have responded to this threat on a personal and community level. The purpose of this study was to explore the perceptions of gay men about AIDS, and how they responded to these perceptions. Data were gathered
AIDS Info On-Line: a computer-based information system for college campuses.: J Am Coll Health. 1990 Sep;39(2):90-4. Unique Identifier : AIDSLINE MED/91036458; Wolitski RJ; Rhodes F; AIDS Research & Education Project, California State University,; Long Beach.
Using peer educators for a classroom-based AIDS program.: J Am Coll Health. 1990 Sep;39(2):96-9. Unique Identifier : AIDSLINE MED/91036459; Richie ND; Stenroos D; Getty A; Health Education Department, Florida Atlantic University, Boca; Raton.; Frustration over their inability to reach sizable numbers of students for an AIDS education and prevention program, even after employing peer educators, prompted the staff of the SHS to devise a classroom-based program. Sixty-five faculty members gave permission for the presentations, and the students represented a ca
Current epidemiologic evidence and case reports of occupationally acquired HIV and other bloodborne diseases.: Infect Control Hosp Epidemiol. 1990 Oct;11(10 Suppl):558-60. Unique Identifier : AIDSLINE MED/91036855; Gerberding JL; Department of Medicine, San Francisco General Hospital,; California.; Studies in which noninfected persons shared households with human immunodeficiency virus (HIV)-infected family members and friends, and had substantial though non-sexual contact with them revealed no transmissions of the HIV virus. These results suggest a similar low risk for healthcare workers, particularly those who
Risk reduction through testing, screening and infection control precautions--with special emphasis on needlestick injuries [published erratum appears in Infect Control Hosp Epidemiol 1991 Apr;12(4):210]: Infect Control Hosp Epidemiol. 1990 Oct;11(10 Suppl):563-5. Unique Identifier : AIDSLINE MED/91036857; De Laune S; Transmission of the hepatitis B virus (HBV) and human immunodeficiency virus (HIV) pose substantial risks to institutional healthcare employees working with blood. While the risk of contracting hepatitis B in the hospital setting is much greater than the probability of acquiring HIV, the cost of treating the acquired
The pharmacist's role in controlling bloodborne infections with emphasis on procuring safe injection systems.: Infect Control Hosp Epidemiol. 1990 Oct;11(10 Suppl):566-8. Unique Identifier : AIDSLINE MED/91036858; Hanan ZI; Mercy Hospital, Rockville Centre, New York.; The hospital s department of pharmacy plays an important role in lessening the risk of bloodborne disease transmission through its influences in the coordination and control of the hospital s drug distribution system, intravenous (IV) admixture service and purchasing decisions with regard to injectable drug products.
The dilemmas of introducing routine HIV testing into the intensive care unit.: Intensive Care Nurs. 1990 Sep;6(3):118-23. Unique Identifier : AIDSLINE MED/91036870; Jones SE
The Indiana Veterans Home and AIDS patients [letter]: Indiana Med. 1990 Sep;83(9):666. Unique Identifier : AIDSLINE MED/91036913; Crouse B
Glucocorticoid therapy for severe Pneumocystis carinii pneumonia.: J Infect. 1990 Sep;21(2):131-7. Unique Identifier : AIDSLINE MED/91037072; Miller RF; Semple SJ; University College and Middlesex School of Medicine, Middlesex; Hospital, London, U.K.; The majority of patients with AIDS and Pneumocystis carinii pneumonia respond to treatment with either high-dose cotrimoxazole or IV pentamidine. Glucocorticoids have been given as adjuvant therapy in those patients who fail to respond to cotrimoxazole or pentamidine. This article discusses the role of glucocorticoi
Incidence of malaria and efficacy of oral quinine in patients recently infected with human immunodeficiency virus in Kinshasa, Zaire.: J Infect. 1990 Sep;21(2):167-73. Unique Identifier : AIDSLINE MED/91037077; Colebunders R; Bahwe Y; Nekwei W; Ryder R; Perriens J; Nsimba K; Turner A; Francis H; Lebughe I; Van der Stuyft P; et al; Project SIDA, Department of Public Health, Kinshasa, Zaire.; There is concern that the impaired cell mediated immunity caused by the human immunodeficiency virus may increase the risk of severity of Plasmodium falciparum infection and could lead eventually to a decreased response to standard antimalarial treatment. In 1986, at Mama Yemo Hospital, Kinshasa,
The value of serum cryptococcal antigen in the diagnosis of cryptococcal infection in patients infected with the human immunodeficiency virus.: J Infect. 1990 Sep;21(2):175-81. Unique Identifier : AIDSLINE MED/91037078; Nelson MR; Bower M; Smith D; Reed C; Shanson D; Gazzard B; Department of Medicine, Westminister Hospital, London, U.K.; Serum cryptococcal antigen titres were measured in 828 HIV-infected patients with pyrexia, 69 of whom had meningism. Serum cryptococcal antigen was positive in 17 patients of whom 16 had meningism with cryptococcus isolated from their CSF. The other patient had no meningism, had no evidence of cryptococcal infection o
Ciprofloxacin as a cause of Clostridium difficile-associated diarrhoea in an HIV antibody-positive patient [see comments]: J Infect. 1990 Sep;21(2):205-7. Unique Identifier : AIDSLINE MED/91037082; Hillman RJ; Rao GG; Harris JR; Taylor-Robinson D; Division of Sexually Transmitted Diseases, Clinical Research; Centre, Harrow, Middlesex, U.K.; Ciprofloxacin is an uncommon cause of pseudomembranous colitis. A case is described in which diarrhoea was associated with the presence of clostridial toxin in an HIV-infected patient and the possible implications are discussed.
Latent HIV infection following a low degree of exposure and the importance of repeated western blot [letter]: J Infect. 1990 Sep;21(2):225-7. Unique Identifier : AIDSLINE MED/91037088; Patey O; Lafaix C; Breuil J; Dublanchet A; Israel G; Chapel A; Dormont D
Immunology of AIDS related to psoriasis.: J Invest Dermatol. 1990 Nov;95(5):38S-40S. Unique Identifier : AIDSLINE MED/91037113; Duvic M; Dept of Dermatology, University of TX Medical School, Houston; 77030.; The association of severe psoriasis with HIV infection, which dysregulates and destroys the human immune system, supports the hypothesis that psoriasis is an immunologically mediated disease. Psoriasis and Kaposi s sarcoma share angiogenesis as basic early findings and could both be caused by differential cytokine exp
Heterosexual transmission of human immunodeficiency virus among intravenous drug users.: J Infect Dis. 1990 Nov;162(5):1007-11. Unique Identifier : AIDSLINE MED/91037147; Battjes RJ; Pickens RW; Amsel Z; Brown LS Jr; Division of Clinical Research, National Institute on Drug Abuse,; Rockville, MD 20857.; To examine sexual transmission of human immunodeficiency virus (HIV) among heterosexual intravenous drug users (IVDUs), HIV antibody status of IVDUs with intravenous drug-using sexual partners (IVSPs) was compared with that of IVDUs with no IVSPs. Initial bivariate analyses indicated IVDUs with IVSPs were more likely
The role of human immunodeficiency virus infection in pneumococcal bacteremia in San Francisco residents.: J Infect Dis. 1990 Nov;162(5):1012-7. Unique Identifier : AIDSLINE MED/91037148; Redd SC; Rutherford GW 3d; Sande MA; Lifson AR; Hadley WK; Facklam RR; Spika JS; Division of Bacterial Diseases, Centers for Disease Control,; Atlanta, GA 30333.; Human immunodeficiency virus (HIV) is an important risk factor for invasive pneumococcal disease, but information on clinical course and infecting serotypes is limited. To help develop strategies to reduce the morbidity due to invasive pneumococcal disease, episodes of pneumococcal bacteremia were identified by retros
Clinical correlation and genetic polymorphism of the human immunodeficiency virus proviral DNA obtained after polymerase chain reaction amplification.: J Infect Dis. 1990 Nov;162(5):1025-30. Unique Identifier : AIDSLINE MED/91037150; Genesca J; Wang RY; Alter HJ; Shih JW; Department of Transfusion Medicine, Warren G. Magnuson Clinical; Center, National Institutes of Health, Bethesda, MD 20892.; Polymerase chain reaction (PCR) was used to amplify a long sequence of human immunodeficiency virus (HIV) DNA, to assess the correlation between PCR signal and clinical stage of disease, and to demonstrate the genotypic variability of different HIV isolates. Twenty-four (96%) of 25 anti-HIV-reactive patients and none
Coccidioidomycosis in human immunodeficiency virus-infected patients.: J Infect Dis. 1990 Nov;162(5):1165-9. Unique Identifier : AIDSLINE MED/91037171; Galgiani JN; Ampel NM; Medical Service, VA Medical Center, Tucson, AZ 85723.; Coccidioidomycosis is at best a complicated fungal infection; often it is life-threatening. Coccidioidomycosis is confined epidemiologically to the southwestern region of the USA, and most cases have occurred in that area, particularly in Arizona. However, we have seen several cases in San Francisco in patients with o
Treatment of symptomatic children infected with human immunodeficiency virus [letter; comment]: J Infect Dis. 1990 Nov;162(5):1209-10. Unique Identifier : AIDSLINE MED/91037183; Shearer WT
Pseudofailure of zidovudine prophylaxis after a human immunodeficiency virus-positive needlestick [letter]: J Infect Dis. 1990 Nov;162(5):1211-2. Unique Identifier : AIDSLINE MED/91037185; Lucey D; Milum S; Lindquist C; Andrzejewski C; Benton J; Boswell RN
Disseminated bacille Calmette-Guerin infection in an AIDS patient 30 years after BCG vaccination [letter]: J Infect Dis. 1990 Nov;162(5):1216. Unique Identifier : AIDSLINE MED/91037189; Armbruster C; Junker W; Vetter N; Jaksch G
AZT demonstrates anti-HIV-1 activity in persistently infected cell lines: implications for combination chemotherapy and immunotherapy.: J Infect Dis. 1990 Dec;162(6):1233-8. Unique Identifier : AIDSLINE MED/91037196; Pincus SH; Wehrly K; Laboratory of Microbial Structure and Function, National; Institute of Allergy and Infectious Diseases, Hamilton, Montana; 59840.; A sensitive and quantitative focal immunoassay has been used to measure the effects of three different therapeutic agents on tissue culture cells infected with human immunodeficiency virus (HIV). The effects of the drugs were studied on both acutely and persistently infected CD4+ cell lines. The three agents, azidothy
Quantitative detection of brain aberrations in human immunodeficiency virus type 1-infected individuals by magnetic resonance imaging.: J Infect Dis. 1990 Dec;162(6):1245-51. Unique Identifier : AIDSLINE MED/91037198; Sonnerborg A; Saaf J; Alexius B; Strannegard O; Wahlund LO; Wetterberg L; Department of Infectious Diseases, Roslagstull Hospital,; Stockholm, Sweden.; The brains of 65 individuals with antibodies to human immunodeficiency virus type 1 (HIV-1), 20 HIV-1 seronegative homosexual men, and 75 heterosexual controls were examined by a quantitative magnetic resonance imaging technique. A white matter aberration was detected most frequently in patients with AIDS-related comp
The use of corticosteroids in Pneumocystis carinii pneumonia.: J Infect Dis. 1990 Dec;162(6):1365-9. Unique Identifier : AIDSLINE MED/91037216; Bozzette SA; Department of Medicine, University of California, San Diego.
Seroprevalence of human T cell leukemia viruses in selected populations of homosexual men.: J Infect Dis. 1990 Dec;162(6):1370-2. Unique Identifier : AIDSLINE MED/91037217; Meyer RD; Moudgil T; Detels R; Phair JP; Hirsch MS; Ho DD; Department of Medicine, University of California School of; Medicine, Los Angeles 90048.; This study sought to define the seroprevalence of human T cell leukemia virus (HTLV) types I and II in selected populations of homosexual men. Serum specimens were screened for antibodies to HTLV and to human immunodeficiency virus (HIV) by enzyme immunoassay; successive testing of specimens with positive results was
Confocal microscopic detection of human immunodeficiency virus RNA-producing cells.: J Infect Dis. 1990 Dec;162(6):1373-8. Unique Identifier : AIDSLINE MED/91037218; Lewis DE; Minshall M; Wray NP; Paddock SW; Smith LC; Crane MM; Department of Microbiology, Baylor College of Medicine, Houston,; TX 77030.; A central anomaly in the pathogenesis of AIDS is that few actively infected CD4+ cells (1 in 10(4)-10(5) have been detected in the peripheral blood, even though dramatic depletion (often greater than 90%) of CD4+ cells is the hallmark of disease progression. A sensitive, 35S-based human immunodeficiency virus (HIV) RN
Frequency of indeterminate western blot tests in healthy adults at low risk for human immunodeficiency virus infection. The NIAID AIDS Vaccine Clinical Trails Network.: J Infect Dis. 1990 Dec;162(6):1379-82. Unique Identifier : AIDSLINE MED/91037219; Midthun K; Garrison L; Clements ML; Farzadegan H; Fernie B; Quinn T; Center for Immunization Research, Rockville, Maryland.; As part of a phase 1 trial of a candidate AIDS vaccine, blood specimens were collected from 168 healthy adult volunteers at minimal or no risk for becoming infected with human immunodeficiency virus type 1 (HIV-1). These specimens were screened for evidence of HIV-1 infection by enzyme immunoassay (EIA) and the Biotec
AIDS: the epidemiological significance of two different mean rates of partner change.: IMA J Math Appl Med Biol. 1990;7(1):27-32. Unique Identifier : AIDSLINE MED/91037405; Jacquez JA; Simon CP; Department of Physiology, University of Michigan, Ann Arbor; 48109.
The role of bacterial cultures from bronchoscopy washings in AIDS related patients.: J La State Med Soc. 1990 Aug;142(8):31-5. Unique Identifier : AIDSLINE MED/91037612; Valainis GT; Parta MJ; Tulane Univ School of Medicine, Infectious Diseases Section.; The clinical significance of bronchoscopy washing cultures for bacteria had been questioned before the era of the acquired immune deficiency syndrome (AIDS), and the procedure was felt to be misleading more than helpful. Little has been mentioned of its utility in AIDS patients undergoing fiberoptic bronchoscopy. The
Human recombinant interleukin-2 induces maturation and activation signals for feline eosinophils in vivo.: J Leukoc Biol. 1990 Dec;48(6):531-40. Unique Identifier : AIDSLINE MED/91037713; Tompkins MB; Novotney C; Grindem CB; Page R; English R; Nelson P; Tompkins WA; Department of Microbiology, Pathology and Parasitology, College; of Veterinary Medicine, North Carolina State University, Raleigh; 27606.; Immunotherapy, with interleukin-2 ( IL-2 ) or IL-2 plus lymphokine-activated killer (LAK) cells, has been used to treat cancer and acquired immunodeficiency syndrome (AIDS) in man. Similarities between feline leukemia virus (FeLV) infection in the cat and human immunodef
Determination of human immunodeficiency virus antibody status in forensic autopsy cases in Vancouver using a recombinant immunoblot assay.: J Forensic Sci. 1990 Sep;35(5):1029-34. Unique Identifier : AIDSLINE MED/91037851; Little D; Ferris JA; Department of Forensic Pathology, University of British Columbia,; Vancouver, Canada.; Sera from 207 forensic autopsy cases were tested for the presence of antibody to the human immunodeficiency virus (HIV) using a recombinant immunoblot assay (RIBA) technique developed by Chiron Corporation of Emeryville, California--the Chiron RIBA-HIV216 test system. Out of these cases, 172 autopsies were of individu
Causes of death in hospitalized intravenous drug abusers.: J Forensic Sci. 1990 Sep;35(5):1143-8. Unique Identifier : AIDSLINE MED/91037860; Klatt EC; Mills NZ; Noguchi TT; Los Angeles County-University of Southern California Medical; Center.; The authors reviewed at autopsy the causes of death of 274 patients with evidence of intravenous drug abuse who had been admitted to a large public hospital. There were 127 who died from diseases unrelated to intravenous drug abuse, and in 41% of these, chronic alcoholism was implicated. Deaths from overdose syndromes
Testing for HIV infection [letter]: J Fla Med Assoc. 1990 Sep;77(9):798-9. Unique Identifier : AIDSLINE MED/91037875; Uzych L
Psychological functioning in a cohort of gay men at risk for AIDS. A three-year descriptive study.: J Nerv Ment Dis. 1990 Oct;178(10):607-15. Unique Identifier : AIDSLINE MED/91037986; Joseph JG; Caumartin SM; Tal M; Kirscht JP; Kessler RC; Ostrow DG; Wortman CB; University of Michigan, Ann Arbor 48109.; This study describes the mental health of a large cohort of gay men participating in the Chicago Multicenter AIDS Cohort Study/Coping and Change Study. Six biannual questionnaires were self-administered between 1984 and 1988. General mental health was determined by the Hopkins Symptom Checklist (HSCL). An abbreviated
Imipenem/cilastatin treatment of acute infections in AIDS/ARC patients.: J Chemother. 1990 Aug;2(4):247-51. Unique Identifier : AIDSLINE MED/91038219; Giacometti A; Pongetti P; Petrelli E; Scalise G; Department of Infectious Diseases, University of Ancona, Italy.; We studied the clinical efficacy and safety of imipenem, a broad spectrum beta-lactam antibiotic, in acute bacterial infections in 21 patients with AIDS or AIDS-related complex (ARC). Imipenem/cilastatin was administered as a 30-min intravenous infusion using a dose of 500 mg/8 h. Bacterial pathogens were isolated bef
Toxoplasmosis of the conus medullaris in a patient with hemophilia A-associated AIDS. Case report.: J Neurosurg. 1990 Dec;73(6):951-3. Unique Identifier : AIDSLINE MED/91038306; Kayser C; Campbell R; Sartorious C; Bartlett M; Department of Surgery, Indiana University Medical Center,; Indianapolis.; Toxoplasma gondii has been reported to be the most common cause of focal brain lesions in patients with acquired immunodeficiency syndrome (AIDS). A case of intramedullary toxoplasmosis of the conus medullaris is reported in a patient with hemophilia A-associated AIDS. The diagnosis is discussed, with particular empha
Needlestick injuries among resident physicians.: J Gen Intern Med. 1990 Sep-Oct;5(5):389-93. Unique Identifier : AIDSLINE MED/91038380; Heald AE; Ransohoff DF; Department of Internal Medicine, Yale University School of; Medicine, New Haven, CT 06510-8025.; OBJECTIVE: To assess the frequency and causes of needlestick injuries in medical and surgical housestaff. DESIGN: A retrospective survey. SETTING: Urban university teaching hospital. PARTICIPANTS: 386 housestaff; 221 responded. INTERVENTION: Survey questionnaire. MAIN RESULTS: 1) Frequency of needlestick: Of 221 respo
Caring for people with AIDS and HIV infection in hospital-based primary care practice.: J Gen Intern Med. 1990 Sep-Oct;5(5):446-50. Unique Identifier : AIDSLINE MED/91038390; Makadon HJ; Delbanco SF; Delbanco TL; Department of Medicine, Beth Israel Hospital, Boston, MA 02215.
Sexual practices: are physicians addressing the issues?: J Gen Intern Med. 1990 Sep-Oct;5(5 Suppl):S78-81. Unique Identifier : AIDSLINE MED/91038422; Lewis CE; UCLA Department of Medicine, UCLA School of Medicine 90024-1685.; The literature suggests that prior to 1981, the only groups concerned with sexual history taking were urologists, psychiatrists, and gynecologists. The appearance of AIDS, however, has made competency in this area of interviewing essential for all primary care physicians. The teaching of sexual history taking presents
Novel and sensitive enzyme immunoassay (immune-complex-transfer enzyme immunoassay) for antihuman T cell leukemia virus type 1 IgG in human serum using recombinant gag-env hybrid protein as antigen.: J Clin Lab Anal. 1990;4(5):355-62. Unique Identifier : AIDSLINE MED/91038559; Kohno H; Kohno T; Sakoda I; Ishikawa E; Fuji Research Laboratories, Kyowa Medex Co., Ltd., Shizuoka,; Japan.; A novel and sensitive enzyme immunoassay (immune-complex-transfer enzyme immunoassay) for antihuman T cell leukemia virus type 1 IgG (anti-HTLV-1 IgG) in human serum using recombinant gag(14-139)-env-(197-295) hybrid protein is described. Anti-HTLV-1 IgG in test serum was reacted with dinitrophenyl biotinyl bovine ser
Effect of azidothymidine on soluble CD4 levels in patients with AIDS or AIDS-related complex.: J Clin Lab Anal. 1990;4(5):396-8. Unique Identifier : AIDSLINE MED/91038565; Reddy MM; Vodian M; Grieco MH; R.A. Cooke Institute of Allergy, St. Luke's-Roosevelt Hospital; Center, New York, NY 10019.; Circulating soluble CD4 (sCD4) levels were measured in 20 patients (11 with the acquired immunodeficiency syndrome [AIDS] and 9 with AIDS-related complex [ARC]) treated with azidothymidine ( AZT ) and in 12 patients (nine with AIDS and three with ARC) w
Histopathological changes in simian immunodeficiency virus infection.: J Pathol. 1990 Sep;162(1):67-75. Unique Identifier : AIDSLINE MED/91038576; Baskerville A; Ramsay A; Cranage MP; Cook N; Cook RW; Dennis MJ; Greenaway PJ; Kitchin PA; Stott EJ; Public Health Laboratory Service, Centre for Applied Microbiology; and Research, Division of Pathology, Salisbury, Wiltshire, U.K.; The histological lesions were studied in seven rhesus and three cynomolgus monkeys infected with simian immunodeficiency virus for periods ranging from nine weeks to 18 months. Lymphoreticular changes included hyperplasia, follicular involution and depletion, and one animal had amyloidosis of the spleen. Hyperplastic
Methodological issues in AIDS clinical trials. A symposium sponsored by the National Institute of Allergy and Infectious Diseases and Food and Drug Administration. Bethesda, Maryland, November 20-21, 1989. Proceedings.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S1-147. Unique Identifier : AIDSLINE MED/91038722
The need for early randomization in the development of new drugs for AIDS.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S10-5. Unique Identifier : AIDSLINE MED/91038723; Chalmers TC; Boston Veterans Administration Medical Center, Department of; Health Policy and Management, Harvard University School of Public; Health, Boston, Massachusetts 02115.
Methodological issues in AIDS clinical trials. Issues in the testing of drug combinations.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S104-7. Unique Identifier : AIDSLINE MED/91038724; Schoenfeld DA; Department of Medicine, Harvard Medical School, Boston,; Massachusetts.
Methodological issues in AIDS clinical trials. Application of the combination index method in the design of a clinical antiretroviral trial: ACTG 068.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S111-3 discussion S114-9. Unique Identifier : AIDSLINE MED/91038726; Mildvan D; Ruprecht R; Krown S; Pettinelli C; Department of Medicine, Beth Israel Medical Center, New York, NY; 10003.
Methodological issues in AIDS clinical trials. Intent-to-treat analysis.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S120-3. Unique Identifier : AIDSLINE MED/91038727; Tsiatis A; Division of Biostatistics, Dana-Farber Cancer Institute, Harvard; University, Boston, Massachusetts 02115.
Methodological issues in AIDS clinical trials. Data monitoring and sequential analysis--an academic perspective.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S124-33. Unique Identifier : AIDSLINE MED/91038728; DeMets DL; Biostatistics Center, University of Wisconsin, Madison.
Methodological issues in AIDS clinical trials. Analysis and interpretation of trial results. Discussion.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S134-6 discussion S137-8. Unique Identifier : AIDSLINE MED/91038729; Hauptman L; Segreti A; Division of Biometrics, U.S. Food and Drug Administration,; Rockville, Maryland.
Methodological issues in AIDS clinical trials. Discussion. Incorporation of trial results into clinical practice.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S139-44 discussion S145-7. Unique Identifier : AIDSLINE MED/91038730; Corey L; Del Vecchio P; Brown L; Thompson M; Department of Laboratory Medicine, University of Washington,; Seattle.
Design considerations for AIDS trials.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S16-9. Unique Identifier : AIDSLINE MED/91038731; Byar D; Biometry Branch, National Cancer Institute, Bethesda, Maryland; 20892.
Methodological issues in AIDS clinical trials. Introduction.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S2-3. Unique Identifier : AIDSLINE MED/91038732; Hoth D; Division of AIDS, National Institute of Allergy and Infectious; Diseases, National Institutes of Health, Rockville, Maryland.
Implications of an alternative approach to dose-response trials.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S20-6. Unique Identifier : AIDSLINE MED/91038733; Sheiner LB; Department of Laboratory Medicine, School of Medicine, University; of California, San Francisco 94143.
Methodological issues in AIDS clinical trials. Discussion. Design of clinical trials--approaches to clinical trials design.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S27-36 discussion S37-9. Unique Identifier : AIDSLINE MED/91038734; Lietman P; Temple R; Harrington M; Peck C; Division of Clinical Pharmacology, Johns Hopkins University; School of Medicine, Baltimore.
Methodological issues in AIDS clinical trials. Statutory and regulatory framework for drug approval.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S4-9. Unique Identifier : AIDSLINE MED/91038735; Burlington DB; Office of Drug Evaluation II, Food and Drug Administration,; Rockville, Maryland 20857.
Rationale for variations in clinical trial design in different HIV disease stages.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S40-4. Unique Identifier : AIDSLINE MED/91038736; Volberding PA; Department of Oncology/Medicine, University of California, San; Francisco General Hospital 94110.
AIDS in intravenous drug users: issues related to enrollment in clinical trials.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S45-50. Unique Identifier : AIDSLINE MED/91038737; Craven DE; Liebman HA; Fuller J; Hagerty C; Cooley TP; Saunders CA; Steger KA; Libman H; Boston University School of Medicine, Boston City Hospital,; Massachusetts 02118.
Evaluation of the AIDS dementia complex in clinical trials.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S51-60. Unique Identifier : AIDSLINE MED/91038738; Price RW; Sidtis JJ; Department of Neurology, University of Minnesota, Minneapolis.; The AIDS dementia complex (ADC) is one of the most common and important causes of morbidity associated with infection by human immunodeficiency virus type 1 (HIV-1). The evaluation of ADC in clinical trials is significant not only because of the clinical impact of this syndrome, bu
Practical issues and considerations in the design of clinical trials for HIV-infected infants and children.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S61-3. Unique Identifier : AIDSLINE MED/91038739; Pizzo PA; Pediatric Branch, National Cancer Institute, Bethesda, Maryland; 20892.
Methodological issues in AIDS clinical trials. Discussion. Design of clinical trials--end points.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S72-4 discussion S75-6. Unique Identifier : AIDSLINE MED/91038742; Schooley RT; Strongin W; Hawley P; University of Colorado Health Sciences Center, Denver.
Evaluation of active control trials in AIDS [see comments]: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S82-7. Unique Identifier : AIDSLINE MED/91038744; Fleming TR; Department of Biostatistics, School of Public Health and; Community Medicine, University of Washington, Seattle.; In settings in which effective standard treatment exists, active control trials provide an ethically appealing approach to evaluating experimental therapies by allowing all patients to be randomized either to a promising new regimen or to the standard as it would be routinely delivered in clinical practice. This paper
Methodological issues in AIDS clinical trials. Discussion. Design of clinical trials--active control (equivalence) trials.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S88-91 discussion S92-4. Unique Identifier : AIDSLINE MED/91038745; Richman D; Itri L; Johnson MF; Eigo J; Department of Pathology and Medicine, University of California,; San Diego.
Effectiveness of multidrug therapies in tuberculosis.: J Acquir Immune Defic Syndr. 1990;3 Suppl 2:S97-8. Unique Identifier : AIDSLINE MED/91038747; Sbarbaro J; Department of Medicine, School of Medicine, University of; Colorado, Denver 80204.
Epidemic and classic Kaposi's sarcoma of the feet. A comparative study.: J Am Podiatr Med Assoc. 1990 Sep;80(9):469-70. Unique Identifier : AIDSLINE MED/91