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Abstract: BACKGROUND: Despite improved survival with HAART, prognosis of AIDS-associated progressive multifocal leukoencephalopathy remains poor; cases of progressive multifocal leukoencephalopathy have been discribed on HAART, some showing features of immune reconstitution syndrome. Others have shown a beneficial effect of infl ...
http://www.aegis.com/conferences/croi/2004/506.html
File Name: 506.html, Size: 8KB, Last Modified: Sunday, February 08, 2004 at 8:12:04 PM
Abstract: PATHOGENESIS: Progressive multifocal leukoencephalopathy is a demyelinating disease of the central nervous system caused by infection and reactivation of JC-virus. About 5% of all HIV-infected patients develop this fatal disease. Although pathogenesis is not completely understood, progressive multifocal leukoencephalo ...
http://www.aegis.com/pubs/ine/1999/oct/a99a0353.html
File Name: a99a0353.html, Size: 7KB, Last Modified: Thursday, October 28, 1999 at 8:12:04 PM
Abstract: OBJECTIVE: Progressive multifocal leukoencephalopathy is caused by polyomavirus JC in immunosuppressed patients. JC virus genotypes are identified by sequence analysis of the viral genome. Despite the prevalence of acquired immunodeficiency syndrome in sub-Saharan Africa, few cases of progressive multifocal leukoencep ...
http://www.aegis.com/pubs/ine/1999/aug/a9980709.html
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Abstract: Italian scientists report the effect of highly active antiretroviral therapy (HAART) on progressive multifocal leukoencephalopathy in HIV-infected patients with JC virus DNA. In a letter to the editor of the New England Journal of Medicine, the authors report that among 10 AIDS patients with progressive multifocal leuk ...
http://www.aegis.com/news/ads/1998/ad981831.html
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Abstract: BACKGROUND: Progressive multifocal leukoencephalopathy affects about 4 percent of patients with the acquired immunodeficiency syndrome (AIDS), and survival after the diagnosis of leukoencephalopathy averages only about three months. There have been anecdotal reports of improvement but no controlled trials of therapy w ...
http://www.aegis.com/aidsline/1998/jul/m9871051.html
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Abstract: Reactivation of latent JC virus in immunodeficient subjects can lead to a demyelinating disease following lytic oligodendrocyte infection. It is known as idiopathic CD4+ lymphocytopenia and rarely occurs in immunosuppressed patients who are not infected by HIV. We describe a case of persistent idiopathic CD4+ lymphocy ...
http://www.aegis.com/aidsline/1998/feb/m9820715.html
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Abstract: Progressive multifocal leukoencephalopathy is a subacute demyelinating disease of the central nervous system due to an opportunistic infection by a polyomavirus, most often JC virus, which predominantly infects oligodendrocytes. Progressive multifocal leukoencephalopathy used to be a rare condition, usually complicati ...
http://www.aegis.com/aidsline/1998/jan/m9810045.html
File Name: m9810045.html, Size: 9KB, Last Modified: Thursday, January 29, 1998 at 6:29:23 AM
Abstract: Progressive multifocal leukoencephalopathy, a formerly rare disease that chiefly occurred in persons with underlying lymphoma and chronic lymphocytic leukemia, is now seen with increasing frequency in the era of acquired immunodeficiency syndrome. Progressive multifocal leukoencephalopathy is currently estimated to ar ...
http://www.aegis.com/aidsline/1997/oct/m97a0976.html
File Name: m97a0976.html, Size: 9KB, Last Modified: Tuesday, October 28, 1997 at 8:12:04 PM
Abstract: Purpose: Progressive multifocal leukoencephalopathy (PML) is increasingly described as a late complication of the acquired immune deficiency syndrome (AIDS). The purpose of this study is to evaluate retrospectively the ophthalmologic, clinical, and investigational aspects of AIDS-associated PML. Methods: The authors e ...
http://www.aegis.com/news/ine/1996/sep/m9690577.html
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Abstract: Progressive multifocal leukoencephalopathy is a viral-induced demyelinating disease of the central nervous system usually occurring in the immunocompromised individual. The incidence of progressive multifocal leukoencephalopathy has risen sharply over the past decade because of widespread human immunodeficiency virus ...
http://www.aegis.com/conferences/6/jan/m9610648.html
File Name: m9610648.html, Size: 9KB, Last Modified: Sunday, January 28, 1996 at 8:12:04 PM
Abstract: Progressive multifocal leukoencephalopathy (PML), also known as progressive multifocal leukoencephalitis, is a rare and usually fatal disorder that is characterized by progressive damage (-pathy) or inflammation (-itis) of the white matter (leuko-) of the brain (-encephalo-) at multiple locations (multifocal). It occur ...
http://www.aegis.com/topics/oi/oi-pml.html
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Abstract: Progressive multifocal leukoencephalopathy, a common complication of infections with human immunodeficiency virus (HIV), occurs in as many as 3.8% of patients with the acquired immunodeficiency syndrome (AIDS). We report 16 cases and review 12 previously reported cases of progressive multifocal leukoencephalopathy ass ...
http://www.aegis.com/news/ine/1987/sep/m8790127.html
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Abstract: INTRODUCTION: Progressive multifocal leukoencephalopathy is a demyelinating disease resulting from an opportunistic infection of the central nervous system by JC papovavirus. It mostly occurs in patients with an underlying immunosuppressive disorder. In the era of acquired immunodeficiency syndrome it is observed with ...
http://www.aegis.com/pubs/ine/2000/dec/a00c0357.html
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Abstract: AEGIS, Fifth International Congress Drug Therapy in HIV Infection, Glasgow, HIV5, HIV, HIV infection, AIDS. Fifth International Congress Drug Therapy in HIV Infection 22-26 October, 2000 Glasgow, UK. RECOVERY FROM PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY FOLLOWING DIRECTLY OBSERVED HIGHLY ACTIVE A ...
http://www.aegis.com/conferences/hiv-glasgow/2000/p387.html
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Abstract: Progressive multifocal leukoencephalopathy is a rare viral-induced demyelinating disease associated to immunodeficiency. A 10-year-old boy with AIDS is reported, who developed subacute cerebellar signs and symptoms with multiple cranial nerve involvement and dementia . A computed to ...
http://www.aegis.com/news/ine/1998/apr/m9840355.html
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Abstract: OBJECTIVE: To describe the occurrence of progressive multifocal leukoencephalopathy (PML) in association with Wiskott-Aldrich syndrome, an X-linked recessive disorder with impairment of both cellular and humoral immunity. DESIGN: A detailed analysis of this patient s clinical illness, immunologic factors, neuroradiogr ...
http://www.aegis.com/conferences/4/jul/m9470420.html
File Name: m9470420.html, Size: 10KB, Last Modified: Thursday, July 28, 1994 at 8:12:04 PM
Abstract: Progressive multifocal leukoencephalopathy in a child with acquired immunodeficiency syndrome (AIDS). Arq Neuropsiquiatr. 1997 Mar;55(1)122-5. Unique Identifier : AIDSLINE MED/97473729 Araujo AP; Pereira HS; Oliveira RH; Frota AC; Esperanca JC; Duarte F; Department of Pediatrics, Universidade Federal ...
http://www.aegis.com/conferences/4/apr/m9840355.html
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Abstract: Biotinylated DNA:DNA in situ hybridization was used for determining the presence of JC virus in brain tissues of 67 patients thought to have progressive multifocal leukoencephalopathy. Sixty patients had acquired immunodeficiency syndrome (AIDS) or other illnesses that decreased the cell-mediated immunity. Two patient ...
http://www.aegis.com/news/ine/1993/dec/m93c0155.html
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Abstract: Disseminated histoplasmosis (DH) and progressive multifocal leukoencephalopathy occur in acquired immunodeficiency syndrome (AIDS). At autopsy, DH patients with central nervous system involvement almost always show extensive involvement of the lungs and reticuloendothelial system in addition to the brain, and progress ...
http://www.aegis.com/conferences/2/jul/m9270326.html
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Abstract: We present the case of a 26-year-old human immunodeficiency virus-seropositive man who developed progressive multifocal leukoencephalopathy as the initial manifestation of AIDS. He appears to have responded dramatically to therapy with 3 -azido-3 -deoxythymidine ( ...
http://www.aegis.com/news/ine/1990/oct/m90a0578.html
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Abstract: A 33-year-old homosexual man with symptoms and signs of a focal brain process was subsequently found to have an acquired immune deficiency syndrome (AIDS) with biopsy-proven progressive multifocal leukoencephalopathy. This report reemphasizes the association of progressive multifocal leukoencephalopathy with AIDS and ...
http://www.aegis.com/news/ine/1984/nov/m84b0073.html
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Abstract: An unusual case of Progressive Multifocal Leukoencephalopathy (PML) in a Haitian man with AIDS is reported. The lesions involving both white and gray matter are described radiologically and at post-mortem. The implications regarding neuroradiological differential diagnosis in AIDS as well as PML virulence in this type ...
http://www.aegis.com/news/ine/1989/sep/m8990492.html
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Abstract: A 39-year-old intravenous drug user presented with dysarthria and a syndrome of the left cerebellar hemisphere. While in hospital, he developed progressive brainstem findings. Repeated CT scans revealed a lucency in the white matter of the left cerebellar hemisphere. Brainstem auditory and short-latency somatosensory ...
http://www.aegis.com/news/ine/1989/jun/m8960593.html
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Abstract: Of the 93 acquired immune deficiency syndrome (AIDS) patients autopsied between 1983 and 1986, 27 had evidence of viral encephalitis of which 3 had progressive multifocal leukoencephalopathy (PML), confirmed by electron microscopy. Using in situ hybridization with biotinylated JC virus probes, paraffin sections from t ...
http://www.aegis.com/aidsline/1989/jan/m8910066.html
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Abstract: Antigens of human polyomaviruses, the etiologic agents of progressive multifocal leukoencephalopathy (PML), and of human immunodeficiency virus were localized in paraffin sections from brains of six patients who died with the acquired immunodeficiency syndrome. Immunostaining revealed polyomaviral antigens in oligoden ...
http://www.aegis.com/news/ine/1989/feb/m8920056.html
File Name: m8920056.html, Size: 10KB, Last Modified: Wednesday, January 07, 2009 at 5:24:19 AM
Abstract: Progressive multifocal leukoencephalopathy, a demyelinating disease of the central nervous system, is caused by a polyomavirus. This opportunistic virus is demonstrable in affected brain tissue obtained by biopsy or at autopsy. The disease commonly occurs in immunocompromised patients secondary to lymphoproliferative ...
http://www.aegis.com/news/ine/1988/sep/m8890073.html
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Abstract: Two human immunodeficiency virus seropositive patients with progressive multifocal leukoencephalopathy (PML) exhibited a dramatic though incomplete recovery of neurologic function and have survived for more than 30 months since the onset of symptoms. PML was the initial manifestation of the acquired immune deficiency ...
http://www.aegis.com/news/ine/1988/oct/m88a0531.html
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Abstract: A wide variety of neurologic conditions associated with the acquired immunodeficiency syndrome (AIDS) have been attributed to human immunodeficiency virus (HIV) infection of the central nervous system (CNS). Tissue samples from the brains of three patients with AIDS, diagnosed as having CNS toxoplasmosis on the basis ...
http://www.aegis.com/aidsline/1988/jun/m8860328.html
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Abstract: A new double-label immunocytochemical method detects JC virus (JCV) early (T-antigen) and late (capsid) proteins simultaneously in cryostat sections of progressive multifocal leukoencephalopathy (PML) brain tissue from both acquired immunodeficiency syndrome (AIDS) and non-AIDS patients. T-antigen is detected with a m ...
http://www.aegis.com/news/ine/1988/dec/m88c0118.html
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Abstract: Cytologic preparations from two cases of progressive multifocal leukoencephalopathy (PML) were obtained by stereotactically guided needle biopsies using computerized tomograms of the brain. Case 1 was a 32-year-old man with an acquired immunodeficiency syndrome-related complex. Case 2 was a 71-year-old man with chroni ...
http://www.aegis.com/news/ine/1987/oct/m87a0314.html
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