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Abstract: We studied biopsy specimens from ten male Caucasian patients with oral hairy leukoplakia. All patients either had the acquired immunodeficiency syndrome (AIDS) or showed symptoms of the AIDS related complex (ARC). On the basis of the specimens studied, we describe the histopathological features of this new entity and ...
http://www.aegis.com/news/ine/1988/oct/m88a0588.html
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Abstract: In 3 patients seropositive for HIV 1 (2 homosexual men and 1 female drug addict), we found oral hairy leukoplakia on the lateral margin of their tongues. DNA of Epstein-Barr virus (EBV) and Human Papillomavirus (HPV) were identified in cellular DNA by molecular-virological means using Southern blot hybridization and/o ...
http://www.aegis.com/aidsline/1988/jul/m8870086.html
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Abstract: To define the role of Epstein-Barr virus (EBV) in the pathogenesis of oral hairy leukoplakia, 13 human immunodeficiency virus-seropositive men with clinical and histologic evidence of oral hairy leukoplakia were enrolled in an open-label trial of orally administered acyclovir th ...
http://www.aegis.com/news/ine/1988/apr/m8840070.html
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Abstract: The first case of oral hairy leukoplakia in an HIV-negative patient with multiple myeloma is reported. The patient is a 56-year old man who has had monoclonal gammopathy of undetermined significance since 1986 and has been treated for a symptomatic multiple myeloma since 1993. The clinical and histopathologic findings ...
http://www.aegis.com/conferences/7/apr/m9741559.html
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Abstract: Oral hairy leukoplakia is almost only described in patients infected by the human immunodeficiency virus. Epstein-Barr virus, sometimes associated with human papillomavirus, is always involved in the occurrence of these lesions. We have investigated two cases of oral hairy leukoplakia with the goal of detecting EBV an ...
http://www.aegis.com/aidsline/1993/jun/m9360730.html
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Abstract: Oral hairy leukoplakia is an epithelial lesion of the tongue associated with productive infection by Epstein-Barr virus (EBV). However, no data concerning the pattern of EBV latent gene expression have been reported, and it remains unresolved whether true latent infection occurs in basal cell layers of oral hairy leuk ...
http://www.aegis.com/conferences/2/aug/m9280110.html
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Abstract: Clinical and histologic morphology of oral hairy leukoplakia in 85 HIV-positive patients were studied. Differential diagnosis of oral hairy leukoplakia in comparison with the normal lingual and buccal epithelium from both HIV-positive and HIV-negative patients, and with other tongue conditions was also examined. Oral ...
http://www.aegis.com/conferences/2/jun/m9260961.html
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Abstract: Oral hairy leukoplakia was initially reported only in HIV-infected patients and was considered pathognomonic for HIV infection. The presence of Epstein-Barr virus and the decrease in Langerhans cells seem to be necessary for the development of oral hairy leukoplakia. HIV antigen is not present in oral hairy leukoplaki ...
http://www.aegis.com/conferences/2/jan/m9210584.html
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Abstract: Oral hairy leukoplakia was first described in homosexual men infected with the human immunodeficiency virus. It is thought to be caused by infection with both the Epstein-Barr virus and human papillomavirus. We report 59 cases of oral hairy leukoplakia. The disease was diagnosed in patients in all risk groups and was ...
http://www.aegis.com/news/ine/1990/may/m9050111.html
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Abstract: "Hairy" leukoplakia of the mouth is an unusual form of leukoplakia that is seen only in HIV-positive individuals. It consists of fuzzy white patches on the tongue, and less frequently, elsewhere in the mouth. It may resemble thrush, a type of candida infection that, in adults, is also associated with HIV and AIDS. Hair ...
http://www.aegis.com/topics/oi/oi-ohl.html
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Abstract: We report the case of a 58-year-old renal transplant patient who developed oral hairy leukoplakia. Examination for HIV-1 and HIV-2 infection was negative. Biopsy of the lateral tongue showed ballooned prickle cells and electron microscopy revealed herpes-type viruses. In situ hybridization and examinations with the So ...
http://www.aegis.com/news/ine/1989/jan/m8910090.html
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Abstract: Oral hairy leukoplakia was treated in six patients with (a) acyclovir (i.v. or p.o.), (b) 0.1% vitamin-A acid solution or (c) human beta-interferon-gel (10(5) I.E./g) in a total of 23 therapeutic courses. In 5/6 patients, acyclovir (7.5 mg/kg every 8 h i.v. or 5 x 400 mg p.o. ov ...
http://www.aegis.com/news/ine/1989/aug/m8980791.html
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Abstract: 10 specimens taken from oral hairy leukoplakia were compared to 8 histological preparations from hairy tongue. We found 9 criteria helpful concerning the histopathologic differential diagnosis of these entities. Oral hairy leukoplakia shows a gently papillated surface, a prominent horny layer with confluent bacterial ...
http://www.aegis.com/news/ine/1988/nov/m88b0383.html
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Abstract: AEGIS, AIDS Daily Summary, HIV, AIDS, HIV infection, opportunistic infections. var gaJsHost = (https: = document.location.protocol) ? "https:ssl. : "http:www. document.write(unescape(3Cscript src= + gaJsHost + "google-analytics.com/ga.js' type=text/javascript'3E%3C/script%3E"ion" CONTENT=In a study p ...
http://www.aegis.com/news/ads/1988/ad881572.html
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Abstract: A study of 19 people (73% on HAART) with HIV-associated oral hairy leukoplakia (OHL) and Epstein-Barr virus (EBV) replication found that treatment with high dose oral valacyclovir (Valtrex), one gram every eight hours for a month, could inhibit productive replication of EBV. Walling and colleagues at the University of ...
http://www.aegis.com/pubs/i-base/2004/ib040501-17.html
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Abstract: Catie, AEGiS, HIV, AIDS, Oral hairy leukoplakia, OHL, High-dose Valtrex, tongue, EBV, Epstein Barr Virus, acyclovir. INFECTION FIGHTERS: High-dose Valtrex for oral hairy leukoplakia TreatmentUpdate 139 - 2003 November / December; Volume 15 Issue 7 Hosein SROral hairy leukoplakia (OHL) is the name given to ...
http://www.aegis.com/pubs/catie/2003/cate13905.html
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Abstract: OBJECTIVE--To assess the ability of primary care physicians to identify physical findings associated with human immunodeficiency virus (HIV) infection. DESIGN--Standardized patient examination. PARTICIPANTS--A total of 134 general internists and family practitioners were randomly selected after stratifying by year of ...
http://www.aegis.com/conferences/6/jan/m9610303.html
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Abstract: Oral hairy leukoplakia appears as white vertical stripes on the lateral borders of the tongue and occurs almost exclusively in HIV infected patients. The clinical appearance of hairiness is a result of emergence of floss of the parakeratinized epithelial surface. The etiologic agent seems to be Epstein-Barr virus, whi ...
http://www.aegis.com/conferences/3/oct/m93a0139.html
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Abstract: Clinical and etiopathogenetic features of oral hairy leukoplakia in 5 patients positive for Human Immunodeficiency Virus were studied. Oral hairy leukoplakia were located on the lateral borders of the tongue and showed a corrugated/hairy aspect in all the cases. Histological examination showed hyperparakeratosis, acan ...
http://www.aegis.com/news/ine/1993/jul/m9370938.html
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Abstract: The Epstein-Barr virus (EBV) immediate early gene product BZLF1 was localized by indirect immunofluorescence to the cytoplasm of the basal epithelial layer at the lateral border and dorsum of tongue in human immunodeficiency virus-infected and -seronegative patients. Two biopsies of oral hairy leukoplakia revealed a s ...
http://www.aegis.com/news/ine/1992/jan/m9210129.html
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Abstract: We report our experience of oral hairy leukoplakia in HIV seropositive patients. Etiopathogenesis and relationship between oral hairy leukoplakia and HIV infection are briefly discussed, as well as its prognostic value. ...
http://www.aegis.com/news/ine/1991/mar/m9130271.html
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Abstract: While oral hairy leukoplakia has been observed predominantly in patients with HIV-infection at various stages, recent reports have shown that HL may also occur in patients immunosuppressed for other reasons. This report describes oral hairy leukoplakia in a heart transplant recipient with negative HIV serology. The hi ...
http://www.aegis.com/aidsline/1990/oct/m90a0089.html
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Abstract: Oral hairy leukoplakia occurs almost exclusively in human immunodeficiency virus (HIV)-infected patients and is predictive for the development of acquired immunodeficiency syndrome (AIDS). It presents as a white plaque with a rough surface, most commonly on the sides of the tongue. The eruption is frequently overlooke ...
http://www.aegis.com/news/ine/1990/oct/m90a0097.html
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Abstract: To compare the therapeutic effects of surgical excision and orally administered acyclovir therapy on symptomatic oral hairy leukoplakia, 45 homosexual men who were seropositive for human immunodeficiency virus participated in a 3-month open-label study. In the 14 patients who ha ...
http://www.aegis.com/news/ine/1990/feb/m9020487.html
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Abstract: Oral hairy leukoplakia is generally found only in HIV-seropositive individuals or in those who are at risk of developing this infection; its occurrence is accepted to be a reliable predictor for the development of AIDS in those patients who are not already suffering from this disease. This report describes an 18-year- ...
http://www.aegis.com/news/ine/1990/jan/m9010087.html
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Abstract: Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus that infects nearly every human being by young adulthood. Most EBV infections occur asymptomatically during childhood, but EBV is associated with a wide variety of human diseases including the infectious mononucleosis syndrome, Hodgkin's lymphoma, African Burki ...
http://www.aegis.com/pubs/rita/2000/ri001203.html
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Abstract: Patients with AIDS and other immunodeficiencies have a very high risk of developing non-Hodgkin s lymphoma (NHL). Epstein-Barr virus is found in about 50% of all AIDS lymphomas, including virtually all central nervous system lymphomas. There are a number of indications that EBV is ...
http://www.aegis.com/news/ine/1996/jun/m9660046.html
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Abstract: Oral hairy leukoplakia (HL) is a remarkable lesion associated with Epstein-Barr virus (EBV) found in persons infected with the human immunodeficiency virus. The clinical and histologic features of HL are characteristic and distinctive. However, none of these features are entirely specific for HL, and we consider that ...
http://www.aegis.com/news/ine/1989/sep/m8990129.html
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Abstract: Oral hairy leukoplakia (HL) is a lesion that occurs predominantly on the tongue in HIV-infected persons. Evidence strongly indicates that HL is related to the presence of Epstein-Barr virus in the epithelial cells. The lesion appears on the lateral border of the tongue as a painless, white plaque varying in size from ...
http://www.aegis.com/aidsline/1989/sep/m8990127.html
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Abstract: Oral hairy leukoplakia (HL) has been regarded as an early sign of HIV infection, and its clinical importance related to the poor outcome of the patients has been emphasized. Initially, HL was observed exclusively among male homosexuals, but subsequently demonstrated in all risk groups of HIV infection. The patient des ...
http://www.aegis.com/news/ine/1989/oct/m89a0061.html
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