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Abstract: Mycobacterium avium complex isolates from 27 patients without AIDS and from 76 patients with AIDS were analyzed with the Gen-Probe Rapid Diagnostic System for Mycobacterium avium complex, and a retrospective chart review was performed to determine clinical significance of the isolates. While 87% of isolates from AIDS ...
http://www.aegis.com/news/ine/1989/aug/m8980760.html
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Abstract: A 38-year-old HIV-positive man had several attacks of high fever associated with extensive perspiration over a 10-week period. Simultaneously, he developed molluscum contagiosum-like papules and an erythematous plaque on the face, ulcerated papules on both shoulders and buttocks and subcutaneous nodules on the arms. H ...
http://www.aegis.com/conferences/7/feb/m9720885.html
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Abstract: Pairs of 11 antimicrobial agents were tested in vitro for their ability to act synergistically against three strains of Mycobacterium avium complex isolated from patients with acquired immune deficiency syndrome. From the combinations tested, four drugs (ethambutol, rifampin, ciprofloxacin, and erythromycin) were sele ...
http://www.aegis.com/aidsline/1989/mar/m8930401.html
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Abstract: A reconsideration of the laboratory methods used for primary isolation of mycobacteria other than Mycobacterium tuberculosis is needed due to the increasingly recognized importance of such mycobacterial infections in immunocompromised patients. One example of this is the severe opportunistic infections caused by Mycob ...
http://www.aegis.com/news/ine/1989/jan/m8910140.html
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Abstract: Pulmonary disease caused by Mycobacterium avium complex usually occurs in patients with chronic lung disease or deficient cellular immunity, and its prevalence is increasing. We describe 21 patients (mean age, 66 years) with such infection without the usual predisposing factors, representing 18 percent of the 119 pati ...
http://www.aegis.com/news/ine/1989/dec/m89c0644.html
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Abstract: The present study was conducted to evaluate human leukocyte antigen (HLA) associations with Disseminated Mycobacterium avium complex (DMAC) infection in North American Caucasian homosexual HIV/AIDS patients. Analysis of 176 DMAC cases and 176 matched controls studied showed a weak association with DRB1*15011 (Odds Rati ...
http://www.aegis.com/conferences/iac/2000/wepea4094.html
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Abstract: Antigen fingerprinting based on surface glycolipid antigens was applied to the epidemiology of clinical isolates of the Mycobacterium avium complex from 128 acquired immunodeficiency syndrome (AIDS) and 31 non-AIDS patients from several different regions of Spain . The application of ...
http://www.aegis.com/pubs/ine/2000/jun/a0060190.html
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Abstract: The HLA class II allele, DR2 (DRB1*1501), has been repeatedly found to be associated with development of tuberculosis and leprosy. We searched for associations of these and other class II alleles with disseminated Mycobacterium avium complex infection (DMAC) in North American Caucasian homosexual AIDS patients. Molecu ...
http://www.aegis.com/aidsline/2000/may/a0051794.html
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Abstract: Members of the Mycobacterium avium complex are the most frequently encountered opportunistic bacterial pathogens among patients in the advanced stage of AIDS. Two clinical isolates of the same strain, numbers 397 and 417, were obtained from an AIDS patient with disseminated M. avium complex infection before and after ...
http://www.aegis.com/aidsline/1999/jul/a9971103.html
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Abstract: In the present study restriction fragment length polymorphism analyses with the recently described insertion sequence IS1245 as a probe was performed with clinical Mycobacterium avium complex strains cultured in Denmark during a 2-y ...
http://www.aegis.com/pubs/ine/1999/may/a9950328.html
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Abstract: Disseminated Mycobacterium avium complex (DMAC) infection is a common complication of advanced HIV disease, and is an independent predictor of mortality. The clinical features of DMAC infection are fever, weight loss, abdominal pain, anemia, elevated serum alkaline phosphatase, and elevated serum lactate dehydrogenase ...
http://www.aegis.com/aidsline/1999/mar/a9930854.html
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Abstract: The purpose of this study was to assess the distribution of Mycobacterium avium serovars isolated from AIDS patients in Sao Paulo and Rio de Janeiro. Ninety single site or multiple site isolates from 75 patients were examined. The most frequent serovars found were 8 (39.2%), 4 (21.4%) and 1 (10.7%). The frequency of m ...
http://www.aegis.com/aidsline/1998/apr/m9840701.html
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Abstract: The aim of this study was to investigate a potential expansion of gammadelta T cells in AIDS patients in response to disseminated infection with Mycobacterium avium complex. Liver-derived lymphocytes and peripheral blood lymphocytes were obtained from 5 AIDS patients with disseminated Mycobacterium avium complex infec ...
http://www.aegis.com/aidsline/1998/feb/m9820433.html
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Abstract: Clarithromycin can ameliorate symptoms and improve survival in disseminated Mycobacterium avium complex (DMAC) infection. Optimal combinations of this drug with other agents remains unknown. Granulocyte colony stimulating factor (G-CSF) is a cytokine that can improve phagocytosis of Mycobacterium avium complex in vitr ...
http://www.aegis.com/conferences/6/nov/m96b0616.html
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Abstract: Mycobacterium avium complex infection is a common complication of the later stages of AIDS. Although a recognized cause of oral lesions, atypical mycobacteria are rarely detected in AIDS-related oral ulceration. Here we report a case of oral ulceration in a patient in the later stages of AIDS in which atypical mycobac ...
http://www.aegis.com/conferences/6/oct/m96a1104.html
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Abstract: To compare the safety and efficacy of four regimens in treatment (Rx) of disseminated Mycobacterium avium complex disease (DMAC) in patients (pts) with AIDS. From 3/95 to 2/96, patients with AIDS and DMAC or presumptive DMAC were randomized to receive one of four 3-drug regimens in a factorial desig ...
http://www.aegis.com/conferences/iac/1996/lbb6025.html
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Abstract: The postantibiotic effect (PAE) of clarithromycin alone and in combination with ethambutol was determined for two clinical blood isolates of Mycobacterium avium complex. An average PAE, ranging from 5.5 to 18.0 h, was noted for each isolate at each clarithromycin concentration except when isolate B was exposed to clar ...
http://www.aegis.com/conferences/6/jun/m9660731.html
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Abstract: This data supports the use of clarithromycin and ethambutol in the treatment of DMAC. Addition of G-CSF to a regimen of clarithromycin and ethambutol may increase survival in DMAC and should be studied prospectively. ...
http://www.aegis.com/conferences/croi/1996/192.html
File Name: 192.html, Size: 8KB, Last Modified: Sunday, January 28, 1996 at 8:12:04 PM
Abstract: Mycobacterium avium complex strains and Mycobacterium paratuberculosis are closely related intracellular pathogens affecting humans and animals. M. avium complex infections are a leading cause of morbidity and mortality in AIDS patients, and M. paratuberculosis is the agent of Johne s disease in ruminants. Genetic man ...
http://www.aegis.com/news/ine/1995/sep/m9590645.html
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Abstract: Danish isolates of Mycobacterium avium complex were serotyped by the use of seroagglutination. The most prevalent serovars among patients with AIDS (n = 89) were 4 and 6, while among non-AIDS patients the most prevalent serovars were 1, 6, and 4, with no major differences between those in patients with pulmonary disea ...
http://www.aegis.com/conferences/5/may/m9550441.html
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Abstract: Five human immunodeficiency virus-infected patients with disseminated Mycobacterium avium complex infection had progressive weight loss and persistent fever despite multidrug antimycobacterial therapy. These patients were given daily low-dose oral dexamethasone (typically 2 mg/day) as adjunctive therapy. All had subst ...
http://www.aegis.com/conferences/5/apr/m9540792.html
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Abstract: Recovery of Mycobacterium avium complex organisms from 412 lysis-centrifugation (Isolator) concentrates of blood specimens obtained from human immunodeficiency virus-positive individuals was attempted with the following media (and Isolator concentrate inoculum volumes): BACTEC 12B broth (0.2 and 1.0 ml), Lowenstein-Je ...
http://www.aegis.com/conferences/5/apr/m9540655.html
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Abstract: The value of the smear for acid-fast bacilli in predicting pulmonary tuberculosis is unclear in a setting where there is a high prevalence of Mycobacterium avium complex in respiratory specimens. To evaluate the impact of a high prevalence of M. avium complex on the predictive value of the acid-fast bacilli smear for ...
http://www.aegis.com/aidsline/1995/mar/m9530072.html
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Abstract: For identification of the features of disseminated Mycobacterium avium complex (DMAC) in human immunodeficiency virus (HIV)-infected children, a retrospective medical record review of 31 long-term survivors with transfusion-acquired HIV was conducted. Nine patients developed DMAC defined as positive isolation of M. av ...
http://www.aegis.com/conferences/4/dec/m94c0120.html
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Abstract: Preliminary studies showed that roxithromycin possessed significant in vitro activity against a variety of atypical mycobacteria such as the Mycobacterium avium complex, M. scrofulaceum, M. szulgai, M. malmoense, M. xenopi, M. marinum, and M. kansasii and rare pathogens such as M. chelonae and M. fortuitum. In this in ...
http://www.aegis.com/conferences/4/dec/m94c0171.html
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Abstract: For 273 patients evaluated for disseminated Mycobacterium avium complex infection, a total of 1,047 mycobacterial blood cultures (MBCs) were submitted; the M. avium complex was recovered from 140 (13%) of the specimens. Results for the paired MBCs were highly concordant: in 392 of 462 (85%) culture sets, both MBCs wer ...
http://www.aegis.com/conferences/4/sep/m9490976.html
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Abstract: Organisms of the Mycobacterium avium complex cause disseminated blood-borne infection in patients with AIDS, who acquire the infection mainly through the gastrointestinal tract. Prior to causing infection, M. avium must colonize and invade the intestinal mucosa. This study examined the ability of several serovars of t ...
http://www.aegis.com/conferences/4/aug/m9480713.html
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Abstract: Analysis of Mycobacterium avium complex serovars isolated from AIDS patients from southeast Brazil.. Mem Inst Oswaldo Cruz. 1997 Jul-Aug;92(4)471-5. Unique Identifier : AIDSLINE MED/98027832 Saad MH; Vincent V; Dawson DJ; Palaci M; Ferrazoli L; Fonseca L de S; Laboratorio de Hanseniase, Instituto Osw ...
http://www.aegis.com/conferences/4/apr/m9840701.html
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Abstract: In this study the combined antimycobacterial effects of rifabutin and clarithromycin against Mycobacterium avium complex were evaluated. The susceptibility to rifabutin (0.5 and 2.0 mg/L) and clarithromycin (1.0 and 4.0 mg/L) was determined as well as the antibacterial effects of the combined drugs. A total number of ...
http://www.aegis.com/conferences/3/nov/m93b4571.html
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Abstract: The in-vitro activity of clarithromycin, temafloxacin, and ethambutol were assessed by MIC, FIC and intra-macrophage killing determinations alone and in various combinations against ten pigmented and ten non-pigmented strains of Mycobacterium avium complex bacteria. Alone, either clarithromycin or temafloxacin were fo ...
http://www.aegis.com/conferences/3/oct/m93a0148.html
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