181 Persistent Lack of Detectable HIV-1 Antibody in a Person With HIV Infection--Utah, 1995
MMWR Morbidity and Mortality Weekly Report, March 8, 1996/Vol. 45/No. 09 Centers for Disease Control and Prevention
SUMMARY: 181 Infection with human immunodeficiency virus (HIV) is diagnosed routinely by the enzyme immunoassay (EIA) for HIV-1 antibody; a nonreactive blood sample is designated as negative without further testing. However, one limitation of this screening algorithm is that a blood sample may be obtained from a patient with recent HIV infection before detectable HIV antibody is present ("window period"). This report describes a patient with confirmed HIV infection in whom EIAs for HIV antibody (HIV-EIAs) were persistently negative beyond the expected "window period."
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