HIV Treatment Bulletin - Vol. 6, No. 7, July 2005

On July 1 Pfizer announced that it has discontinued clinical development of capravirine, an NNRTI with activity against NNRTI-resistant HIV, that was in phase 2 development. This came as no surprise given the complicated drug interactions that make it difficult to use with other PIs or NNRTIs.

Results reported earlier this year at the 12th Annual Conference on Retroviruses and Opportunistic Infections (CROI) indicated no benefit compared to placebo.

Source: Pfizer PR

050710
IB050607-17

©2005. I-BASE HIV Treatment Bulletin. Permission to reproduce courtesy of HIV i-Base, Third Floor East, Thrale House, 44-46 Southwark Street, London SE1 1UN - T: +44 (0) 20 7407 8488 F: +44 (0) 20 7407 8489

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted grants from Boehringer Ingelheim, Elton John AIDS Foundation, Bridgestone / Firestone Trust, the National Library of Medicine, and donations from users like you. Always watch for outdated information. This article first appeared in 2005. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 2005. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content.