AEGiS-GMHC: Common Alternative Therapies: PCM-4 Gay Men's Health CrisisImportant note: Information in this article was accurate in 1993. The state of the art may have changed since the publication date.
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Common Alternative Therapies: PCM-4

Gay Men's Health Crisis: Treatment Issues, Volume 7 no. 11/12 - Winter, 1993/94
Bree Scott-Hartland


PCM-4 is a product combining two components purported to have immunomodulating effects. The two components are an extract ("P") from the porcine spleen and a highly concentrated form of Siberian ginseng.

The oral dosage of these two extracts was developed by Dr. Nicholaus Weger in Munich, West Germany in 1987. The pill was developed after initial studies done with Siberian ginseng suggested that the combination might be capable of increasing T-cells.[1] Other studies from as long ago as 1965 had shown that patients with cancer of the stomach who experienced immune suppression had general improvement with the use of the porcine spleen extract, the polypeptide or "P."

There are reports of some studies in HIV-infected people being conducted, but these studies are either incomplete or have not been published.

PCM-4 is available at health food stores in drops, tablets and capsules and is recommended at about 100mg per day with meals. No toxicities of PCM-4 have been reported, but it is suggested that the compound not be used by those with high blood pressure.

1. Brown, D.J., "PCM-4: New Standard of Excellence in Immunomodulation," Health Store News, Oct./Nov. 1991.

Copyright (c) 1993 - Gay Men's Health Crisis. All rights reserved. Noncommercial reproduction is encouraged.
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Copyright © 1993 - Treatment Issues. Reproduced with permission. Treatment Issues is published twelve times yearly by GMHC, Inc. All rights reserved. Noncommercial reproduction is encouraged. Subscription lists are kept confidential. GMHC Treatment Issues, The Tisch Building, 119 West 24th Street, New York, NY 10011  fredg@gmhc.org  http://www.gmhc.org

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