AEGiS-GMHC: TAT Drug Plans

Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

TAT Drug Plans

TREATMENT ISSUES, Volume 6, Number 8 - September, 1992; The Gay Men's Health Crisis Newsletter of Experimental Therapies
David Gold

Hoffmann-La Roche unveiled its plans for the TAT inhibitor drug, a long-awaited anti-HIV agent. Phase I trials showed the drug to be safe for at least five days. The multi-site trial (ACTG 213) will be a six month dose-ranging trial in people with "early stage" HIV disease. It will be located at ACTG sites in Baltimore, Boston, San Diego and Cleveland. A second Roche-sponsored trial will enroll people with "late stage" HIV-disease and a third ACTG (217) trial is planned for testing the drug in combo with AZT.

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