AEGiS-GMHC: TREATMENT BRIEFS: Promising CD8 Therapy Plus IL-2

Important note: Information in this article was accurate in 1992. The state of the art may have changed since the publication date.

TREATMENT BRIEFS: Promising CD8 Therapy Plus IL-2

The Gay Men's Health Crisis Newsletter of Experimental Therapies - Volume 6, Number 2 - February 1992
Derek Link

Activists are excited about reports of a promising anti-HIV and Kaposi's sarcoma therapy, which reactivates T8 cells. The treatment uses a device, developed by Applied Immune Science, which removes blood from the patient, activates T8 cells and infuses the blood back into the body along with Interleukin-2. In Phase I trials in Miami and Pittsburgh, the therapy was shown to be well tolerated and demonstrated renewed T8 cell activity. Patients had significant remissions of AIDSrelated symptoms such as Kaposi's sarcoma lesions. Phase ll trials are to begin in Miami in March, 1992. It is hoped that these trials will proceed without delay.

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