Subclinical Plasmodium falciparum Infection and HIV-1 Viral Load

Emerg Infect Dis 2007 Feb;13(2):351-3

Kimberly C. Brouwer, ^* Lisa B. Mirel,^* Chunfu Yang,^* Renu B. Lal,^* Margarette S. Kolczak,^* Anne M. Van Eijk,^† John Ayisi,^† Juliana A. Otieno,^‡ Bernard L. Nahlen,^*§ Richard Steketee,^* Ya Ping Shi,^*† and Altaf A. Lal^*
*Centers for Disease Control and Prevention, Atlanta, Georgia, USA; ^†Kenya Medical Research Institute, Kisumu, Kenya; ^‡New Nyanza Provincial General Hospital, Kisumu, Kenya; and §World Health Organization, Geneva, Switzerland

Studies indicate that Plasmodium falciparum infection increases HIV replication in adults. Although malaria-related illness and death are more common in children, and HIV-1 generally progresses faster in children than in adults, to our knowledge the effect of intermittent malaria on HIV-1 viral load has not been directly explored in children. To investigate this issue, we monitored HIV-positive infants from a 1996–2001 birth cohort study in Kisumu, Kenya, a P. falciparum–holoendemic area.

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2007-02-10
eid2007-02-351

Copyright © 2007 - Kimberly C. Brouwer, et al., licensee CDC. This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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