Dale J. Hu, James Baggs, Robert G. Downing, Danuta Pieniazek, Jonathan Dorn, Carol Fridlund, Benon Biryahwaho, Sylvester D.K. Sempala, Mark A. Rayfield, Timothy J. Dondero, and Renu Lal
Emerg Infect Dis 2000 Nov-Dec;6(6):609-15
HIV strain characterization and phylogenetic analysis have played a key role in elucidating epidemiologic and historical aspects of HIV transmission worldwide. In Thailand, for example, molecular analyses of virus isolates documented the independent introduction and spread of two different HIV-1 subtypes, B and E, as well as the increasing proportion of subtype E relative to B in injection drug users over time.
Christopher G. Nelson, Mark A. Iler, Christopher W. Woods, John A. Bartlett, and Vance G. Fowler, Jr.
Emerg Infect Dis 2000 Nov-Dec;6(6):646-48
Coinfection with hepatitis C virus (HCV) and HIV is an emerging public health problem. While coinfection with HIV can accelerate the progression of HCV, the impact of dual infection on other infectious diseases is unknown. We describe the first reported case of meningococcal infection in a patient coinfected with HCV and HIV.
Charles B. Beard,* Jane L. Carter,* Scott P. Keely,† Laurence Huang,‡ Norman J. Pieniazek,* Iaci N.S. Moura,* Jacquelin M. Roberts,* Allen W. Hightower,* Michelle S. Bens,* Amanda R. Freeman,* Sherline Lee,* James R. Stringer,† Jeffrey S. Duchin,* Carlos del Rio,§ David Rimland,§¶ Robert P. Baughman,# Deborah A. Levy,* Vance J. Dietz,* Paul Simon,* and Thomas R. Navin*
Emerg Infect Dis 2000 May-Jun;6(3):265-72
To study transmission patterns of Pneumocystis carinii pneumonia (PCP) in persons with AIDS, we evaluated P. carinii isolates from patients in five U.S. cities for variation at two independent genetic loci, the mitochondrial large subunit rRNA and dihydropteroate synthase. Fourteen unique multilocus genotypes were observed in 191 isolates that were examined at both loci. Mixed infections, accounting for 17.8% of cases, were associated with primary PCP.
Predominance of HIV-1 Subtype A and D Infections in Uganda
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