1999


Emerging Infectious Diseases

Vol. 5, No. 6; November-December

HIV Infection as a Risk Factor for Shigellosis
Jefferson T. Baer,* Duc J. Vugia,*†‡ Arthur L. Reingold,*§ Tomas Aragon,¶ Frederick J. Angulo,# and Williamson Z. Bradford*§**
Emerg Infect Dis 1999 Nov-Dec;5(6):820-23
We investigated cases of shigellosis in San Francisco and Alameda Counties identified during 1996 by active laboratory surveillance to assess the role of HIV infection as a risk factor for shigellosis. Dramatically elevated rates of shigellosis in HIV-infected persons implicate HIV infection as an important risk factor for shigellosis in San Francisco.

Vol. 5, No. 3; May-June

New Cryptosporidium Genotypes in HIV-Infected Persons
Norman J. Pieniazek,* Fernando J. Bornay-Llinares,* Susan B. Slemenda,* Alexandre J. da Silva,* Iaci N. S. Moura,* Michael J. Arrowood,* Oleg Ditrich,¥ and David G. Addiss*
Emerg Infect Dis 1999 May-Jun;5(3):444-49
 Using DNA sequencing and phylogenetic analysis, we identified four distinct Cryptosporidium genotypes in HIV-infected patients: genotype 1 (human), genotype 2 (bovine) Cryptosporidium parvum, a genotype identical to C. felis, and one identical to a Cryptosporidium sp. isolate from a dog. This is the first identification of human infection with the latter two genotypes

Vol. 5, No. 2; March-April

Evaluating Diagnosis and Treatment of Oral and Esophageal Candidiasis in Ugandan AIDS Patients
Maurizio Ravera, Alberto Reggiori, Anna Maria Agliata, Roberto Pidoto Rocco
Emerg Infect Dis 1999 Mar-Apr;5(2):274-77
 A randomized cross-over clinical and endoscopic evaluation of 85 Ugandan patients showed that esophageal candidiasis in AIDS patients with oral candidiasis could be managed without endoscopy and biopsies. Oral lesions, especially when accompanied by esophageal symptoms, were sufficient for diagnosis. Miconazole was more effective than nystatin in treating esophageal candidiasis and could be a valid alternative to more expensive azolic drugs in developing countries

Vol. 5, No. 1; January-February

Dual and Recombinant Infections: An Integral Part of the HIV-1 Epidemic in Brazil
Artur Ramos,*† Amilcar Tanuri,† Mauro Schechter,† Mark A. Rayfield,* Dale J. Hu,* Maulori C. Cabral,† Claudiu I. Bandea,* James Baggs,‡ and Danuta Pieniazek*
Emerg Infect Dis 1999 Jan-Feb;5(1):65-74
 We systematically evaluated multiple and recombinant infections in an HIV-infected population selected for vaccine trials. Seventy-nine HIV-1 infected persons in a clinical cohort study in Rio de Janeiro, Brazil, were evaluated for 1 year. A combination of molecular screening assays and DNA sequencing showed 3 dual infections (3.8%), 6 recombinant infections (7.6%), and 70 (88.6%) infections involving single viral subtypes.

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