In this special "Side Effects" issue, we focus on reports from the 4th International Workshop on Adverse Drug Reactions and Lipodystrophy in HIV, held in San Diego, 22-25 September 2002. Before describing the interesting findings from this workshop, we will provide a list of commonly used anti-HIV drugs and briefly review how therapy for HIV infection was introduced. This review is important because it should give some insight into a group of side effects now called the "HIV lipodystrophy syndrome."
Commonly used anti-HIV drugs in high-income countries:
Nucleoside analogues (nukes)
Nucleotide analogues
Non-nukes (NNRTIs)
Protease inhibitors
A term that's commonly used in North America is HAART — highly active antiretroviral therapy. Historically, this has meant a combination of anti-HIV drugs that can include a protease inhibitor and/or a non-nuke and one or more nukes.
For more in-depth information on HAART, see CATIE's Practical Guide to HAART at www.catie.ca.
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Copyright © 2002 - TreatmentUpdate. Reproduced with permission. Reproduction of this article (other than one copy for personal reference) must be cleared through the Editor, The Canadian AIDS Treatment Information Exchange, 555 Richmond St. West, Suite 505, Box 1104, Toronto, ON, M5V 3B1 • Phone: 416-203-7122 • Toll Free: 1-800-263-1638 • Fax: 416-203-8284 http://www.catie.ca.
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