Table of Contents: CATIE TreatmentUpdate

Table of Contents: CATIE TreatmentUpdate - 2001

Canadian AIDS Treatment Information Exchange
Edited by: Sean Hosein

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TreatmentUpdate 118: June - Vol. 13, No. 2

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Protease inhibitors and blood sugar problems
Inhibiteurs de la protéase et problèmes de sucre sanguin: HoseinSR; In order to find ways to help HAART-users who are experiencing blood sugar/insulin problems, researchers across the globe are studying exactly how indinavir (Crixivan) and nelfinavir (Viracept) cause these problems. At this time we don't have detailed information on the impact of other protease inhibitors (PIs) and their effect on insulin.
Indinavir - effect on sugar and insulin
Indinavir – son effet sur le sucre et l'insuline: HoseinSR; The use of highly active antiretroviral therapy (HAART) has led to dramatic improvements in survival among people with HIV/AIDS (PHAs) in North America and Western Europe who can adhere to complex drug regimens. However, HAART often has side effects, perhaps the most notorious of which is the lipodystrophy syndrome.
Background on glucose — from food to blood sugar
Le point sur le glucose: HoseinSR; In different parts of the intestine these compounds get broken down or digested even further. Sugar or glucose is absorbed from the intestine into blood. The blood carries glucose around the body and cells can then pull in glucose from the blood using specialized proteins called glucose transporters. Once inside the cell, glucose can be "burnt" to release energy.
Extra co-enzyme Q10 for statin-users?
Des suppléments de coenzyme Q10 pour les utilisateurs de « statines »?: HoseinSR; Co-enzyme Q10, or ubiquinone, is a nutrient that is produced in small amounts by the body and is also obtained from food. It plays a key role in helping the body convert food into energy. Co-enzyme Q10 is also an important antioxidant, the need for which increases during HIV infection and in people who use certain lipid-lowering drugs called statins.
Can vitamin E help people recover from hepatitis B?
La vitamine E peut-elle aider les gens à se rétablir de l'hépatite B?: HoseinSR; When someone is first infected with the microbe HBV - hepatitis B virus - it causes inflammation of the liver. Some people can recover from HBV infection, but in people who are not able to recover the virus causes ongoing liver damage, slowly destroying the liver. In some cases, HBV infection eventually leads to liver cancer. Although drugs such as interferon-alpha and 3TC (Epivir, lamivudine) can help some people recover, the majority of people treated with these drugs do not experience a sustained recovery (their recovery is only temporary). Researchers are testing combinations of other drugs to assess their long-term effectiveness.
Study examines link between low levels of zinc and survival
Une étude examine le lien entre un faible taux de zinc et la survie: HoseinSR; Researchers at the University of Miami recruited 121 HIV positive male subjects in the late 1980s and early 1990s as part of a study on malnutrition and HIV infection. They recently analysed the data, looking at the impact of levels of zinc and copper on survival, and published their results, which we report on in this story.
Zinc and the immune system
Le zinc et le système immunitaire: HoseinSR; Nutrients such as copper and zinc are needed by the body in small amounts. Zinc also plays an important role in one of the immune system's major organs - the thymus gland.

TreatmentUpdate 123: November/December - Vol. 13, No. 7: Can delavirdine substitute for ritonavir?; Hepatitis C treatment, HAART and side effects; Toxicity profile of HAART; Rosiglitazone for lipodstrophy?; Actos (pioglitazone); Focus on fat; Metformin — long-term results; Sugar blues and protease inhibitors; Glucose — from food to blood sugar; Lipodystrophy - introduction; Caution with nelfinavir and some lipid-lowering drugs; Trizivir approved in Canada;
TreatmentUpdate 122: October - Vol. 13, No. 6: Looking at soluble CD23 levels to predict lymphoma; Cidofovir for KS lesions; Can low-dose shark cartilage make Kaposi's sarcoma disappear?; Chemo and HAART extend survival with lymphoma; Encouraging news on lymphoma from France; AIDS and lymphoma; New formulation of ddI approved in Canada — Videx EC; Expanded access to tenofovir
TreatmentUpdate 121: September - Vol. 13, No. 5: SIDE EFFECTS - Andractim for HAART-associated breast enlargement; SIDE EFFECTS - Does efavirenz cause breast enlargement?; IMMUNE BOOSTERS - Interleukin-12 may be useful for hepatitis C; ANTI-HIV AGENTS - Study finds HIV subtly damages vision; ANTI-HIV AGENTS - Searching for the right dose of ritonavir-saquinavir; ANTI-HIV AGENTS - Different combinations of ritonavir-indinavir
TreatmentUpdate 120: August - Vol. 13, No. 4: Depression linked to immune system decline in women; Carnitine for high triglycerides; Lipid-lowering drugs and changes to diet can make a difference; Sexual dysfunction and HAART; Immune booster used to fight drug-resistant herpes; Effect of HAART on cervical growths; Switching to nevirapine — results after one year
TreatmentUpdate 119: July - Vol. 13, No. 3: Fosamax for HIV-related bone problems?; Indinavir and bones: Does thickness = strength?; Lipodystrophy — nukes vs. protease inhibitors; Spanish study looks at nevirapine's effect on the liver; Pesticides found in many ginseng supplements in the U.S.; Can ginseng help suppress HIV?; Large Italian study looks at when to start HAART;
TreatmentUpdate 118: June - Vol. 13, No. 2: Protease inhibitors and blood sugar problems; Indinavir - effect on sugar and insulin; Background on glucose — from food to blood sugar; Extra co-enzyme Q10 for statin-users?; Can vitamin E help people recover from hepatitis B?; Study examines link between low levels of zinc and survival; Zinc and the immune system;
TreatmentUpdate 117: May - Vol. 13, No. 1: Bone damage - more than just nukes involved; Australian study links nukes, lactic acid to bone loss;High levels of lactic acid in some users of HAART ;Nukes may be linked to hearing loss; Of power plants and energy shortages; German study finds whey protein supplement boosts antioxidants; Spanish doctors try switching therapy from month to month
TreatmentUpdate 115: February - Vol. 12, No. 11: St. John's wort found to lower nevirapine levels; Are deaths due to liver damage becoming more common?; St. John's wort extract found not helpful for hepatitis C; Canadian researchers study "immune healing"; Kaletra approved in Canada;
TreatmentUpdate 114: January - Vol. 12, No. 10: Some women may be at high risk for anal cancer; DHEA — Cautions and concerns; DHEA for depression?; Changes in DHEA levels in people taking anti-HIV therapy; DHEA — Background; Nukes linked to fat wasting; Triple nuke therapy — results after one year; Switching meds: from protease inhibitors to non-nukes
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TreatmentUpdate 118: June - Vol. 13, No. 2

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