The immune system needs a large amount of high-quality protein every day to perform repairs and make new T-cells, hormones and antioxidant enzymes. These enzymes help to protect cells from the damaging effects of highly active molecules called free-radicals. Research suggests that HIV infection increases the demand for antioxidants, a demand that the body is unable to meet on its own.
To increase the body's ability to make antioxidants, researchers have been conducting studies on people with HIV, giving them supplements of high-quality protein called whey protein. Made from cow's milk, whey protein is a combination of proteins that are easy to digest.
For their two-week study, German researchers enrolled 30 HIV positive subjects (5 female, 25 male) who had an average of 221 CD4+ cells. Subjects took 15 grams of whey protein powder three times daily, for a total of 45 grams per day. They mixed the powder in milk, yogurt or buttermilk. Researchers gave subjects one of two brands of whey protein:
When the results of both treatments were analysed together, researchers found that, on average, levels of the body's major antioxidant, GSH (glutathione), increased by about 32% after two weeks in all subjects. The study was not designed to find out if one brand of whey protein was better than the other. Long-term studies are needed to confirm and extend these findings.
Notes on brand names
Given the many brands of protein powder available, choosing one is not easy. We encourage interested readers to develop a relationship with knowledgeable staff at your local health food store. These people can answer your questions about different brands and prices of whey protein supplements.
REFERENCE
Micke P, Beeh KM, Schlaak JF and Buhl R. Oral supplementation with whey proteins increases plasma glutathione levels of HIV-infected patients. European Journal of Clinical Investigation 2001;31:171-178.
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Copyright © 2001 - TreatmentUpdate. Reproduced with permission. Reproduction of this article (other than one copy for personal reference) must be cleared through the Editor, The Canadian AIDS Treatment Information Exchange, 555 Richmond St. West, Suite 505, Box 1104, Toronto, ON, M5V 3B1 • Phone: 416-203-7122 • Toll Free: 1-800-263-1638 • Fax: 416-203-8284 http://www.catie.ca.
AEGiS is made possible through unrestricted grants from Boehringer Ingelheim, Elton John AIDS Foundation, iMetrikus, Inc., the National Library of Medicine, and donations from users like you. Always watch for outdated information. This article first appeared in 2001. This material is designed to support, not replace, the relationship that exists between you and your doctor.
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