Table of Contents: CATIE TreatmentUpdate

Table of Contents: CATIE TreatmentUpdate - 2000

Canadian AIDS Treatment Information Exchange
Edited by: Sean Hosein

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TreatmentUpdate 104: January - Vol. 11, No. 10

Immunotoxins to the rescue
Les immunotoxines à la rescousse: HoseinSR; For some people, highly active antiretroviral therapy (HAART) has resulted in the remission of AIDS symptoms and prolonged survival. Yet, despite HAART's ability to drive down viral load to five copies or fewer, production of HIV continues. This low-level production of HIV allows the infection to persist and forces people with HIV/AIDS to remain on therapy.
Cytokines can help fight HIV
Les cytokines sont utiles dans la lutte contre le VIH: HoseinSR; Long before AIDS appears, researchers can find subtle defects in the way the immune system works. For example, over time, HIV-infected people appear less able to produce certain chemical messengers (cytokines) needed by the immune system.
HAART as an immune booster
La multithérapie en tant qu'immunostimulant: HoseinSR; Nurses in London, England, recruited nine adult male subjects for this study. At the start of the study, key lab values were as follows: Viral load ranged between 21,000 and 780,000 copies; CD4+ counts ranged between 76 and 474 cells.
A placebo-controlled study of Chinese herbs
Une étude contrôlée contre placebo ayant recours à des herbes chinoises: HoseinSR; Traditional Chinese medicine (TCM) has been used for thousands of years for the prevention and treatment of illness. Infections for which TCM has been used include: Hepatitis; Herpes; Tuberculosis
Curcumin - some issues to consider
Curcumine quelques points à prendre en compte: HoseinSR; Curcumin is a yellow colouring agent found in the spice turmeric. It is curcumin that is responsible for the colour of curry. In Asia, extracts of turmeric have been used for centuries to treat inflammatory conditions such as arthritis. In the 1990s, researchers found that curcumin had anti-HIV activity in lab experiments with cells. As well, curcumin is supposed to have antioxidant properties and may impair the growth of lymphoma.
Curcumin and the immune system
La curcumine et le système immunitaire: HoseinSR; Researchers conducted experiments using curcumin and cells of the immune system such as macrophages and CD4+ cells. These cells, particularly macrophages, play an important role in helping the immune system recognize and fight many of the infections seen in AIDS. Some of the experiments also used mice.
Mistletoe extract for HIV/AIDS?
L'extrait de gui contre le VIH/sida?: HoseinSR; Iscador is a preparation made from European mistletoe. When exposed to it, some tumours and T- cells commit suicide, or apoptosis. Iscador has been injected under the skin in subjects with cancer, causing some tumours to shrink and some subjects to experience remission. It is difficult to assess Iscador's usefulness as an anti-cancer agent, however, because most reports on the drug are written in German.
Curry for cancer?
Le cari contre le cancer?: HoseinSR; B-cells are immune system cells that produce antibodies, which are proteins that help fight against certain infections. The abnormal growth of B-cells can lead to some types of cancer in people with HIV/AIDS. One such cancer is non-Hodgkin's lymphoma, an aggressive tumour that may not respond well to therapy, particularly if it's located in the brain or has spread to several locations.
Predicting lymphoma with soluble CD27
Prédire le lymphome au moyen de la CD27 soluble: HoseinSR; People with HIV/AIDS are at increased risk for developing certain cancers, particularly non-Hodgkin's lymphoma (NHL). Doctors have no way of predicting which of their HIV-positive patients will develop this cancer. According to a research team at the University of California at Los Angeles, a protein called CD27 may be linked to the appearance of NHL

TreatmentUpdate 113: December - Vol. 12, No. 9: Protease inhibitors and pregnancy — reports from the U.S.; Effect of combination therapy on pregnancy — results from Europe; Two German studies find NAC supplements helpful; How nutrient deficiencies occur; Interferon and ribavirin for hepatitis B; Maintenance therapy for TB works
TreatmentUpdate 112: November - Vol. 12, No. 8: Lopinavir - Results after one year; The benefit of HAART in older people; Large study finds hepatitis C virus infection linked to reduced benefit from anti-HIV drugs; Safety and effectiveness of interferon and ribavirin in HIV+ people co-infected with hepatitis C virus; Vitamin A and abnormal cells on the cervix; FDA issues warning about d4T and ddI during pregnancy; Severe nevirapine rash found more likely in women than men
TreatmentUpdate 111: October - Vol. 12, No. 7: Bone marrow stimulant may boost immunity; MAC prevention takes a holiday; Treating parts of the lipodystrophy syndrome -- blood sugar problems; Metformin for blood sugar problems; Metformin - caution and concerns; Calcium supplements help metformin users absorb vitamin B12; Can antioxidants help reduce side effects from ribavirin?; High levels of testosterone develop in some women with body shape changes; A combination of testosterone and exercise for men
TreatmentUpdate 110: September - Vol. 12, No. 6: Different effects of nukes in men and women; Long-term use of hydroxyurea; Indinavir - 3 years and still going strong; Lymphoma in the age of HAART; Anti-viral therapy for lymphoma; Hydroxyurea as anti-viral therapy for brain lymphomas; Will cidofovir be useful against cervical lesions?; Bone Problems may occur with hepatitis treatment
TreatmentUpdate 109: August - Vol. 12, No. 5: Side Effects; Protease inhibitors and loss of fat; Some notes on energy; Nukes and fat cell damage; Helping to repair damaged nerves; Lactic acidosis; Growth hormone helps get rid of fat; Bone problems and anti-HIV therapy; Metformin for insulin and heart problems?; Niacin for cholesterol and weight problems?
TreatmentUpdate 108: June - Vol. 12, No. 4: Does switching from protease inhibitors to nevirapine restore body shape?; GM-CSF raises CD4+ cell counts; Effect of HIV on the menstrual cycle; Large study looks for protease inhibitor side effects; Protease inhibitors, high triglycerides, hormones and bone damage; Help for protease inhibitor-associated diarrhea; HAART may affect thyroid hormone levels; Indinavir and insulin
TreatmentUpdate 107: May - Vol. 12, No. 3: Testosterone and depression in men; Interferon and ribavirin for hepatitis C; CD8+ cell infusions; CD8+ cells - from suppressors to saviours; AMD-3100 - Chemokine blocker under study; Antibiotic holidays may be OK for some
TreatmentUpdate 106: March - Vol. 12, No. 2: Early versus delayed therapy - results from Switzerland; Questions about the early and aggressive use of therapy; Rescue Therapy; Infections after HAART- who is at risk?; The risk of cervical dysplasia;
TreatmentUpdate 105: February - Vol. 12, No. 1: Trizivir - three drugs in one pill; TXU-PAP - early results; Hitting hard, hitting early - one year later; Efavirenz versus indinavir: Who really wins?; Cream reduces reappearance of cervical lesions; Study finds that HAART is OK for some people co-infected with hepatitis B and C virus
TreatmentUpdate 104: January - Vol. 11, No. 10: Immunotoxins to the rescue; Cytokines can help fight HIV; HAART as an immune booster; A placebo-controlled study of Chinese herbs; Curcumin - some issues to consider; Curcumin and the immune system; Mistletoe extract for HIV/AIDS?;
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TreatmentUpdate 104: January - Vol. 11, No. 10

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