Clindamycin

• nausea
• diarrhea (more common with oral clindamycin)
• rash; the rash may go away after "3 to 5 days" even though therapy may be continued
• Erythromycin may block the antibiotic effects of clindamycin

Primaquine

• destruction of red blood cells (hemolysis) can happen in patients who do not produce enough of a certain enzyme (glucose-6-phosphate dehydrogenase). This may particularly affect people of color.
• Methemoglobulinemia: a condition that results in less oxygen being made available to the body

Mepron(R)

This drug has only been recently introduced and experience with it is limited. Side effects reported include:

• diarrhea

930701
CATI4315

Copyright © 1993 - TreatmentUpdate. Reproduced with permission. Reproduction of this article (other than one copy for personal reference) must be cleared through the Editor, The Canadian AIDS Treatment Information Exchange, 555 Richmond St. West, Suite 505, Box 1104, Toronto, ON, M5V 3B1 • Phone: 416-203-7122 • Toll Free: 1-800-263-1638 • Fax: 416-203-8284  http://www.catie.ca