Important note: Information in this article was accurate in December 1999. The state of the art may have changed since the publication date.
Trial protocols are available at the AIDS Clinical Trials Information Service (ACTIS). Call 800-TRIALS-A, or visit the ACTIS Web site at www.actis.org.
A phase III, double-blind, randomized trial to determine the efficacy of bivalent AIDSVAX B/B vaccine in adults at risk of sexually transmitted HIV infection. Study sites include:
A phase I, 68-week cohort trial of the C4-V3 vaccine alone and with IL-12 in HIV positive subjects with maximal suppression of HIV replication and CD4 cell counts greater than 400 cells/mm³. This trial is being conducted in Galveston (409-772-0361). (ACTG A5049)
A 12-month, phase I trial to compare the safety and immunogenicity of three live recombinant canarypox ALVAC HIV vaccines in HIV negative subjects. Study sites include:
A phase I, double-blind, dose-ranging trial of the ALVAC vCP205 vaccine alone or boosted with a clade B oligomeric gp160 vaccine in HIV negative subjects. This study is being conducted in Washington, DC (800-882-3105). (RV124)
A phase I/II, 104-week study to evaluate the safety and immunogenicity of ALVAC HIV vaccines alone and with AIDSVAX B/E gp120 vaccine in infants of indeterminate HIV serostatus born to HIV positive women. Study sites include:
991210
BE991224
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