(BETA) News Briefs: Controversy over Role of New Herpes Virus in Kaposi's Sarcoma


(BETA) News Briefs: Controversy over Role of New Herpes Virus in Kaposi's Sarcoma

Bulletin of Experimental Treatments for AIDS, No. 26 September 1995
Ronald Baker, PhD


Columbia University biologist Yuan Chang, PhD, and epidemiologist Patrick Moor, PhD, presented strong evidence in December 1994 that a newly discovered herpes virus, tagged Kaposi's sarcoma (KS)-associated herpes virus (KSHV), was the cause of KS. The researchers did not isolate KSHV itself, but they discovered DNA of a herpes-like the virus in the KS lesions of people with AIDS. (Science. February 17, 1995).

One outspoken critic of the Columbia findings is Robert Gallo, MD, of the National Cancer Institute (NCI). Some other scientists have become skeptical as well, inclding Parkash Gill, MD, of the University of Southern California and Robert Biggar, MD, at NCI. Still other researchers, such as Steven Miles, MD, of the University of California in Los Angeles (UCLA), remain convinced that KSHV is the cause of KS. Robert Yarchoan, MD, of the NCI and other investigators are planning studies of the anti-herpes drug foscarnet to treat KS, based on the assumption that KSHV plays a key role in the development of the malignancy among people with AIDS. See pages 58-59 of June 1995 BETA for more information on foscarnet treatment of KS.


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Always watch for outdated information. This article first appeard in 1995. This material is designed to support, not replace, the relationship that exists between you and your doctor.

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This information is designed to support, not replace, the relationship that exists between you and your doctor.
©1995. AEGIS.