(BALA) MEDICAL UPDATE: CD4 Cell Function

(BALA) MEDICAL UPDATE: CD4 Cell Function

BEING ALIVE; April 1995
presented by Mark Katz MD and reported by Jim Stoecker

We have suspected that the function of an individual's CD4 cells may be related to how quickly that individual progresses to AIDS. Now, a report out of Amsterdam and published in the Journal of Infectious Diseases establishes a correlation between functional markers of CD4 cells and progression to AIDS. Thus, we need to look at not only the number of CD4 cells, but also how well those cells are functioning to understand the state of an individual's HIV disease. Unfortunately, we do not have readily available tests to measure the function of T-cells. Such tests would also help us to understand the real impact of an antiviral. Though CD4 count might not dramatically increase, CD4 function might be enhanced by a given antiviral.

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