Medical Update: Trimetrexate Approved as PCP Therapy

Medical Update: Trimetrexate Approved as PCP Therapy

Being Alive; March 1994
Mark Katz, MD and reported by Jim Stoecker

Trimetrexate (brand name Neutrexin) was recently approved by the FDA for the treatment of PCP. This drug joins a number of other regimens for treating PCP; ten years back we only had intravenous pentamidine.

Trimetrexate is not considered a first-line drug. Intravenous Bactrim remains the first choice. This new drug, however, is available for those who cannot tolerate or do not respond to IV Bactrim or pentamidine.

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