Protocol For AIDS-Related Lymphoma

Protocol For AIDS-Related Lymphoma

Being Alive; February 1994
Alexandra Levine, MD

At the onset of the AIDS epidemic, it was common practice to leave patients with AIDS-related lymphoma untreated, since no specific therapy had been shown to improve survival. Because of the results of a series of protocols, performed largely at USC, this situation has changed dramatically. With newer treatment strategies, complete remission is achieved in approximately 50-60% of patients, the majority of whom remain in remission.

In patients who have relapsed after remission or who have not responded to initial therapy, no effective alternative treatments have been available. However, two extremely promising experimental therapies are now in trial at USC:

- MGBG, which is given by vein every two weeks,

- a continuous infusion of B4-blocked ricin, a monoclonal antibody directed against the lymphoma cells.

Both of these regimens appear very promising, with excellent preliminary results; both regimens are sponsored by the National Cancer Institute with high priority.

For information regarding these, or other on-going protocols for AIDS-lymphoma, please contact J.J. Anderson, at 213.226.7622.

940201
BA940216

AEGiS is made possible through unrestricted grants from Roxane Laboratories, the National Library of Medicine, and donations from users like you. Always watch for outdated information. Always watch for outdated information. This article first appeared in 1994. This material is designed to support, not replace, the relationship that exists between you and your doctor.

Copyright © 1994 - Beings Alive. Permission granted for noncommercial reproduction, provided that our address and phone number are included if more than short quotations are used. Subscription lists are kept confidential. Being Alive, 621 N. San Vicente Blvd., West Hollywood, CA 90069, Tel - 310.289.2551; FAX - 310.289.9866; Email: BeiAlive@aol.com http://www.beingalivela.org/

This information is designed to support, not replace, the relationship that exists between you and your doctor.
©1994. AEGIS.