MEDICAL UPDATE: More New Drugs


MEDICAL UPDATE: More New Drugs

Being Alive/Los Angeles; Being Alive Newsletter - November 1993
presented by Mark Katz, MD and reported by Jim Stoecker


Conocurvone is a chemical found in smokebush, a plant that grows only in Western Australia. The Journal of the American Chemical Society reports that this chemical was found to prevent HIV from infecting cells in the test tube. And, what is most interesting, conocurvone was able to do this at very low concentrations. The hope is that very little chemical may be highly efficacious. Thus, any toxicities associated with its use would be minimalized. Scientists still do not understand how this chemical works and no human studies are currently planned.

Cosalane is the name of another new drug. Reports indicate that this drug is effective against all strains of HIV in the test tube. Cosalane works by inhibiting the binding of the virus to the T-cell, and thus is active at a point different from that of AZT/ddC/ddI. No further information on this drug is available yet.
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