MEDICAL UPDATE: Study of Passive Immunotherapy


MEDICAL UPDATE: Study of Passive Immunotherapy

Being Alive; March 1992
presented by Mark Katz MD and reported by Jim Stoecker


We have discussed passive immunotherapy a number of times in the past. Locally, the HemaCare study is ongoing, with no results yet available. A recent Journal of Infectious Diseases included the results of a study of passive immunotherapy conducted in Paris. This small study compared nine on the therapy to nine only on AZT. During the course of the study, two of those on passive immunotherapy came down with an opportunistic infection. In contrast, eight in the control group developed an opportunistic infection.

The French researchers found, however, that when the infusions were halted, the patients seemed to get sicker more often than any in the control group. When the transfusions began again, symptoms seemed to recede. It appears that once one starts passive immunotherapy, one may need to stay on it indefinitely.
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