AEGiS-ATN: Kidney, Liver Transplant Study for People with HIV: Atlanta, Baltimore, Boston, Charlottesville, Chicago (2 Centers), Cincinnati, Cleveland, Los Angeles, Miami, New Orleans, New York (2 Centers), Philadelphia (2 Centers), Pittsburgh, San Francisco, Washington DC (2 Centers)

Important note: Information in this article was accurate in 2005. The state of the art may have changed since the publication date.

Kidney, Liver Transplant Study for People with HIV:
Atlanta, Baltimore, Boston, Charlottesville, Chicago (2 Centers), Cincinnati, Cleveland, Los Angeles, Miami, New Orleans, New York (2 Centers), Philadelphia (2 Centers), Pittsburgh, San Francisco, Washington DC (2 Centers)

AIDS TREATMENT NEWS - February 28, 2005
John S. James

Summary: A study of liver and kidney transplants for persons with HIV, at 19 U.S. transplant centers, is open to new patients. Those who may need a transplant later might benefit by getting into the system in advance to avoid delays.

This study of kidney and liver transplantation for persons with HIV, by 19 transplant centers with funding from the U.S. National Institutes of Health, is currently running and is open for new people. Even for patients who do not need a transplant immediately but may need one in the future, it can be important to get into the system now to avoid delays if and when a transplant is necessary. Persons with hepatitis C or hepatitis B are not disqualified and will be considered for this study.

Volunteers must:

Meet the criteria for transplantation;
Have a T-cell count greater than 100 (liver transplant) or greater than 200 (kidney transplant);
Meet HIV viral load criteria depending on which organ is needed;
Patients with certain opportunistic infections in the past will be considered, and need to have a T-cell count above 200;
Pediatric patients are being enrolled in several centers in cities listed above.

For More Information

Specific site and study information can be found at
http://spitfire.emmes.com/study/htr/About_Us/about_us.html
(might require Internet Explorer browser), or
http://www.clinicaltrials.gov/

Related published literature can be found at
http://spitfire.emmes.com/study/htr/Useful_Links/useful_links.html

A poster at the recent Retroviruses conference reported the pilot study results so far:

Michelle Roland, M.D., Don Stablein, Laurie Carlson, and others. 1- to 3-year outcomes in HIV-infected liver and kidney transplant recipients. Conf Retroviruses Opportunistic Infect. 2005 Feb 22-25;12th: Abstract No. 953].

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