AIDS TREATMENT NEWS Issue #355, November 17, 2000
John S. James
The following writeup was released November 15 by the AIDS Treatment Information Service, an agency which provides AIDS treatment information for the U.S. government:
"November 15, 2000: The Food and Drug Administration (FDA) today approved Trizivir for the treatment of HIV in adults and adolescents. Each dose of Trizivir is a fixed-dose combination of Ziagen (abacavir/ABC), Retrovir (zidovudine/AZT), and Epivir (lamivudine/3TC), three nucleoside reverse transcriptase inhibitors (NRTIs) already approved by FDA. Trizivir is not recommended for treatment in adults or adolescents who weigh less than 40 kilograms because it is a fixed-dose tablet.
"Because Trizivir combines a single dose of three drugs into one pill, it may be easier for some patients to comply with their medication regimen. Each component of Trizivir is also available separately. This combination product should only be used by those whose treatment regimens would otherwise include these doses of these three nucleoside analogues. It may be used alone or in combination with other antiretroviral agents for the treatment of HIV infection, but should not be administered concomitantly with abacavir, lamivudine, or zidovudine, which are already contained in Trizivir. The recommended dose is one tablet twice a day.
"For more information, contact our ATIS Health Information Specialists at 1-800-448-0440 or at atis@hivatis.org. You can find the complete FDA press release at http://www.hivatis.org/atisnew.html "
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