Important note: Information in this article was accurate in 1998. The state of the art may have changed since the publication date.
 |
AIDS TREATMENT NEWS Issue #305, October 16, 1998
John S. James
These grants are only for national or international not-for- profit agencies, and are made to the organizations, not to individuals. Applicants need not be U.S. citizens.
"Requests for over $75,000 will be considered only for projects involving collaboration between two separate research groups. These research groups may be at the same or separate institutions."
For either RFP, the letter of intent consists of the cover page, abstract, description/research plan of three pages or less, relevance description (one page maximum), and biographical sketch (not more than two pages). This "letter" is a pre-application screening process. Full applications will be solicited from groups whose letter of intent is accepted.
Immune Reconstitution Topics
All requests for immune reconstitution grants must be assigned to one and only one of five topics:
"Exploration of the mechanisms to facilitate extrathymic generation of T cells from precursor cells;
"Exploration of innovative approaches to therapy that potentially will both control HIV replication and restore or maintain immune function;
"Role of peripheral lymphoid tissue in selecting antigen- responsive T cells;
"Innovative mechanisms to enhance T lymphocyte diversity and function;
"Innovative mechanisms to expand the number and function of memory and naive T lymphocytes. Research topics could include the role of specific immunotherapies, including vaccination, in concert with anti-HIV drugs."
HIV Vaccine Development Topics
The vaccine RFPs must be in one of the following areas:
"Development of new or novel approaches for an HIV vaccine to enhance the qualitative and quantitative cellular and antibody responses, either systemically or in relevant mucosal areas. Approaches may include, for example, the use of novel adjuvants or cytokines in conjunction with HIV antigens, or the evaluation of new or not well-studied targets for developing protective immunity.
"Studies of the mechanisms of HIV antigen presentation and processing that will result in improved methods for enhancing the cellular and antibody responses to HIV antigens. This may include studies with novel vectors.
"Studies on the structure and characterization of HIV antigens that will enhance understanding of immunogenicity, for example, glycosylation of HIV antigens.
"Small well-characterized hypothesis-testing studies that will lead to an increased understanding of the requirements for protective immunity."
How to Submit
Obtain full information and the cover-sheet form either http://www.amfar.org (see the section on grant information), or by calling 212-806-1696 or faxing a written request to 212-806-1601. Phone or fax requests must mention the specific RFP (either Immune Reconstitution in HIV Infection, or HIV Vaccine Development).
The original letter of intent and eight copies must be received by 5:00 p.m. Wednesday November 4, at the AmFAR grants department in New York City; fax or email copies will *not* be accepted.
981016
ATN30502
Copyright © 1998 - AIDS Treatment News. Permission granted for noncommercial reproduction, provided that our address and phone number are included if more than short quotations are used. Subscription lists are kept confidential. AIDS Treatment News, Subscription and Editorial Office: 1233 Locust St., 5th floor Philadelphia, PA 19107 800/TREAT-1-2 toll-free email: aidsnews@critpath.org http://www.aidsnews.org
Subscription Information: Call 800/TREAT-1-2: Businesses, Institutions, Professionals: $270/year. Includes early delivery of an extra copy by email. Nonprofit organizations: $135/year. Includes early delivery of an extra copy by email. Individuals: $120/year, or $70 for six months. Special discount for persons with financial difficulties: $54/year, or $30 for six months. If you cannot afford a subscription, please write or call. Outside North, Central, or South America, add air mail postage: $20/year, $10 for six months. Back issues available. Fax subscriptions, bulk rates, and multiple subscriptions are available; contact our office for details. Please send U.S. funds: personal check or bank draft, international postal money order, or travelers checks. VISA, Mastercard, and purchase orders also accepted. ISSN # 1052-4207
AEGiS is made possible through unrestricted grants from Boehringer Ingelheim, the National Library of Medicine, and donations from users like you. Always watch for outdated information. This article first appeared in 1998. This material is designed to support, not replace, the relationship that exists between you and your doctor.
AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.
Copyright ©1980, 1998. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .