AIDS TREATMENT NEWS Issue #209, October 21, 1994
John S. James
The dose being tested is 1200 mg six times a day. It is widely believed that the usual dose is too low, and was chosen because higher doses would make the drug too expensive. We have not heard of safety problems with the high dose; but potential volunteers will need to discuss possible risks with their physician.
Volunteers must have a T-helper count between 200 and 500; the study is especially seeking persons in this range who are p24 positive. Volunteers must not have active opportunistic infections, nor malignancies likely to require systemic chemotherapy in the next 12 months. They must not be pregnant or breast feeding.
Only the study-related expenses are paid. Volunteers will need to get to Stanford for three screening visits, and for visits at two weeks, four weeks, and monthly after that.
For more information about this trial, call Jane Norris, 415/723-2805.
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