AIDS TREATMENT NEWS Issue #141, December 23, 1991
John S. James
A report in the October 1991 Synopsis, which is published by the Community Consortium, pointed out that this result does not prove conclusively that clofazimine does not work. But there were too few volunteers remaining in the study to prove statistically that it did work -- even if everyone given no treatment developed MAC, and no one else who was taking clofazimine did. The DSMB stopped the study because, after the results seen so far, a positive outcome would have been impossible.
This trial strongly suggest that clofazimine does not work for MAC prophylaxis. For more information, contact the Community Consortium, 3180 18th Street, Suite 201, San Francisco, CA 94110, 415/476-9554
911223
ATN14103
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