(ATDN) Treatment for HIV-related inflammation

(ATDN) Treatment for HIV-related inflammation

Treatment Review #18; April 1995

A drug that has been used for many years to treat malaria, rheumatoid arthritis, and an immune system disease called Lupus, is being tested as a treatment for HIV-related inflammation. Inflammation, a typical immune system response, can lead to undesirable symptoms and aggravation of HIV. The drug being tested, hydroxychloroquine (also called Plaquenil) is available by prescription. Side effects are very rare when used for the conditions for which the drug is approved.

This study will test the combination of hydroxychloroquine and AZT. The researcher conducting this study had good results with an earlier study of the drug in HIV+ people. This new, Phase III study is looking for people who are 18 years or older with a T4 cell count of between 200 and 500. Participants will be divided into two groups. One group will take both drugs. The other group will take AZT alone. Neither the doctor nor the participant will know which treatment is being given. Treatment lasts four months.

950401
ATR01813

Always watch for outdated information. This article first appeard in 1995. This material is designed to support, not replace, the relationship that exists between you and your doctor.

Copyright © 1995 - AIDS Treatment Data Network. If you want to copy, reproduce or excerpt this information, please give us a call at (800) 734-7104. This helps up to keep track of where and how this information is being used. You can also Email us at network@atdn.org http://206.179.124.69/network/index.html

This information is designed to support, not replace, the relationship that exists between you and your doctor.
©1995. AEGIS.