Treatment Review No. 14; November 1994
rHGH is a synthetic version of human growth hormone derived from the pituitary gland. It is made by genetic engineering, and has been approved in the US for several years for treating growth hormone deficiency in children. Side effects of rGHG include joint aches, fevers and high blood pressure. A study sponsored by Serono Laboratories Inc. has shown that human growth hormone can reverse AIDS-associated wasting. The drug is not yet approved by the FDA for this treatment. Serono is currently sponsoring another trial of the drug which will focus on its safety.
Serostim is the brand name for Serono's version of rHGH. Serostim was recently approved for emergency compassionate use by the Health Protection Branch in Canada (1-800-935-8853). Canadian access must be through your doctor who must provide you with a prescription with appropriate dosing. A personal use statement must be submitted with the prescription and both must include the two names of the product, Serostim and recombinant human growth hormone. Canadian officials will expect cash up front. Some insurance companies may cover the cost of rHGH with receipts. The cost at the recommended dosage is $875 a week.
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