(ATDN) Alternative Treatment for PCP Approved

(ATDN) Alternative Treatment for PCP Approved

Treatment Review No. 10; March 1994

NeuTrexin is a new treatment for moderate to severe PCP pneumonia. NeuTrexin is the brand name of a drug called trimetrexate glucoronate. NeuTrexin is given by intravenous injection. NeuTrexin has been approved for use with a drug called leucovorin for people with PCP who can't take Bactrim, either because they can't tolerate it or it's contraindicated. Leucovorin must be given with NeuTrexin to protect human cells against the toxic effects of NeuTrexin. In clinical trials, NeuTrexin with leucovorin was shown to have less efficacy than Bactrim, but it also had fewer side effects. NeuTrexin is expected to be available sometime in January, and is currently available through a Treatment IND program. Call 1-800-537-9978. To give you an idea of how long the approval process can take, the NDA (new drug application) was submitted to the FDA in February 1993. The treatment was approved in December. Information on help in obtaining coverage is available to patients and physicians through the NeuTrexin Reimbursement and Patient Assistance Programs. Call 1-800-8-USBIOS.

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This information is designed to support, not replace, the relationship that exists between you and your doctor.
©1994. AEGIS.