AIDSWEEKLY Plus; Monday, August 13, 2007
Staff Medical Writers

"Demographic characteristics, medical information and pregnancy outcomes were used in this secondary analysis. A total of 1211 women were included in this analysis and 36% were HIV-infected. Among HIV-infected women, maternal parity and prior stillbirths increased with increasing BMI in univariate analysis. Mean birth weight rose as well at 28.3 g [95% confidence interval (CI)=14.0-42.6] of infant weight per BMI unit. Transmission of HIV from mother to child appeared inversely related to BMI when compared according to BMI quartile (P for trend=0.07). In the HIV-uninfected group, infant birth weight increased with increasing BMI, at 32.7 g (95% CI=23.5-41.9) of infant weight per BMI unit. Birth weight increased alongside BMI in both HIV-infected and HIV-uninfected women," wrote Y. Banda and colleagues, University of Zambia.

The researchers concluded: "There is a suggestion that women with lower BMI have a greater risk of perinatal HIV transmission, even after adjustments for HIV viral load and CD4 count."

Banda and colleagues published their study in Tropical Medicine & International Health (Influence of body mass index on pregnancy outcomes among HIV-infected and HIV-uninfected Zambian women. Tropical Medicine & International Health, 2007;12(7):856-61).

For additional information, contact Y. Banda, University of Zambia, School of Medicine, Lusaka, Zambia.

The publisher's contact information for the journal Tropical Medicine & International Health is: Blackwell Publishing Ltd., 9600 Garsington Rd., Oxford OX4 2DG, Oxon, England.

Keywords: Zambia, Lusaka, HIV/AIDS, AIDS, Acquired Immunodeficiency Syndrome, Clinical Trial Research, HIV, Human Immunodeficiency Virus, Nonnucleoside Reverse Transcriptase Inhibitor, Obstetrics, Pregnancy, Virology.

This article was prepared by AIDS Weekly editors from staff and other reports. Copyright 2007, AIDS Weekly via NewsRx.com.

Reference

Banda Y, Chapman V, Goldenberg RL, et al., nfluence of body mass index on pregnancy outcomes among HIV-infected and HIV-uninfected Zambian women, Trop Med Int Health. 2007 Jul;12(7):856-61.

2007-08-13
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