AIDSWEEKLY Plus; Monday, August 11, 2003
Staff Medical Writers

Scientists in the United States "investigated the relationship among habitual exercise, diet, and the presence of metabolic abnormalities (body fat redistribution, dyslipidemia, and insulin resistance) in a cross-sectional study of 120 human immunodeficiency virus (HIV)-infected subjects with the use of bivariate and multivariate regression-analysis models."

"Total and aerobic exercise were significantly and negatively associated with fasting plasma triglyceride levels in the entire sample and in the fat redistribution group," according to A. Gavrila and coauthors at the Beth Israel Deaconess Medical Center in Boston.

"Inverse associations between total or aerobic exercise and insulin resistance were suggestive but did not achieve statistical significance," they reported. "Diastolic blood pressure was significantly and inversely associated with supplemental or total but not habitual dietary intake of vitamin E."

Study results indicated that "exercise and vitamin E intake were independently and negatively associated with several phenotypic manifestations of HIV-associated metabolic syndrome, whereas other macro- or micronutrients did not have comparable significance," the researchers concluded.

Gavrila and colleagues published their study in Clinical Infectious Diseases (Exercise and vitamin E intake are independently associated with metabolic abnormalities in human immunodeficiency virus-positive subjects: A cross-sectional study. Clin Infect Dis. 2003 Jun 15;36(12):1593-601.

For additional information, contact C.S. Mantzoros, Beth Israel Deaconess Medical Center, Division of Endocrinology and Metabolism, 99 Brookline Avenue, RN 325, Boston, MA 02215, USA.

Publisher contact information for the journal Clinical Infectious Diseases is: University of Chicago Press, 1427 E. 60th St., Chicago, IL 60637-2954, USA.

The information in this article comes under the major subject areas of AIDS and HIV, Diet and Nutrition and Endocrinology.

This article was prepared by AIDS Weekly editors from staff and other reports.

Reference

Gavrila A, Tsiodras S, Doweiko J, et al., "Exercise and vitamin E intake are independently associated with metabolic abnormalities in human immunodeficiency virus-positive subjects: a cross-sectional study", Clin Infect Dis. 2003 Jun 15;36(12):1593-601.

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