Pneumocystis Pneumonia in HIV-positive Adults, Malawi

Emerg Infect Dis. 2007 Feb;13(2):325-8

Joep J.G. van Oosterhout,^* Miriam K. Laufer,^† M. Arantza Perez,^* Stephen M. Graham,^* Nelson Chimbiya,* Phillip C. Thesing,^* Miriam J. Álvarez-Martinez,^‡ Paul E. Wilson,^‡ Maganizo Chagomerana,^* Eduard E. Zijlstra,^* Terrie E. Taylor,^*§ Christopher V. Plowe, ^† Comments to Author and Steven R. Meshnick^‡
*University of Malawi College of Medicine, Blantyre, Malawi; †University of Maryland School of Medicine, Baltimore, Maryland, USA; ^‡University of North Carolina, Chapel Hill, North Carolina, USA; and ^§Michigan State University, East Lansing, Michigan, USA

In a prospective study of 660 HIV-positive Malawian adults, we diagnosed Pneumocystis jirovecii pneumonia (PcP) using clinical features, induced sputum for immunofluorescent staining, real-time PCR, and posttreatment follow-up. PcP incidence was highest in patients with the lowest CD4 counts, but PcP is uncommon compared with incidences of pulmonary tuberculosis and bacterial pneumonia.

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2007-02-10
eid2007-02-325

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2007. AEGiS.