2005

In Swaziland, U.S. Preacher Sees His Dream Vanish: Mr. Wilkinson Hits Wall Trying To Push 'Orphan Village'; Rodeo Stars, Safari Guides Feeling Snubbed by the King
Wall Street Journal - December 19, 2005
Michael M. Phillips at michael.phillips@wsj.com
MBABANE, Swaziland - In 2002 Bruce Wilkinson, a Georgia preacher whose self-help prayer book had made him a rich man, heard God s call, moved to Africa and announced his intention to save one million children left orphaned by the AIDS epidemic. In October, Mr. Wilkinson resigned in a huff from the African charity he fo


Brazil Could Turn a Trade Victory Into Defeat
Wall Street Journal - December 16, 2005
Mary Anastasia O'Grady
It s entirely too early to tell if the World Trade Organization s Doha round, launched in November 2001 and set to conclude at the end of next year, can be completed successfully. The very fact that the Hong Kong ministerial this week did not implode means that success remains possible. But one thing firm has come


OraSure Shares Sink on Reports Of False-Positive HIV Tests
Wall Street Journal - December 13, 2005
Cynthia Koons, cynthia.koons@wsj.com
NEW YORK - OraSure Technologies Inc. shares continued to fall, after reports surfaced late last week about a spike in false positive results in San Francisco and New York from its rapid, oral HIV tests. Shares of OraSure were down $1.03, or 8.4%, to $11.23 in afternoon trading on the Nasdaq Stock Market. The stock s lo


Agency Chief Spurs Bioterror Research -- And Controversy
The Wall Street Journal - December 6, 2005
Bernard Wysocki Jr.
-- As Dr. Fauci Pours NIH Funds Into Makers of Vaccines, Some Say He Oversteps A Lawsuit Over Virus Strains BETHESDA, Md. -- Anthony S. Fauci has hundreds of millions of dollars at his disposal to bet on drug companies, hoping they will come up with the next hit vaccine or medicine. Dr. Fauci isn t a venture capitalist


Avian Flu Meets HIV/AIDS
Wall Street Journal - November 22, 2005
Frederick Kempe, Thinkingglobal@wsj.com
Just when you thought you had heard all the worst-case scenarios about a bird-flu pandemic spreading among humans, the germ expert elites are conjuring up one that trumps them all. Call it H5N1 meets HIV/AIDS, the collision of the virus world s King Kong and Godzilla. The horror scenario, outlined below, reinforces the


Wyeth Hires Vaccine Pioneer
Wall Street Journal - November 2, 2005
Scott Hensley, scott.hensley@wsj.com
In a coup for drug maker Wyeth, Emilio Emini, a pioneer in HIV vaccines, is joining the company to head vaccine research and development. Dr. Emini, 51 years old, comes to Wyeth from the International AIDS Vaccine Initiative, in New York, where he was senior vice president for vaccine development. The nonprofit group,


Nonprofit Is Given Licenses to Make AIDS Compounds
Wall Street Journal - November 1, 2005
Marilyn Chase, marilyn.chase@wsj.com
Merck & Co. and Bristol-Myers Squibb Co. gave royalty-free licenses to the International Partnership for Microbicides to develop gels or creams to shield women from the AIDS virus. The licenses grant IPM rights to distribute three Merck compounds and one Bristol-Myers Squibb compound in developing countries.


NIH to Launch Study of AIDS Vaccine
Wall Street Journal - October 11, 2005
Marilyn Chase, Staff Reporter of The Wall Street Journal
The National Institutes of Health said it is launching a study of an AIDS vaccine that combines strains of the deadly virus found all over the world, in what many believe is the first attempt at a truly global AIDS vaccine. To date, most experimental vaccines used strains from one or two regions, often concentrating on


NGOs on Drugs
Wall Street Journal - October 5, 2005
Alec van Gelder
It is in the nature of governments to overreach themselves without considering the consequences of their actions. And, as philosopher Edmund Burke observed back in the 18th century, the greater the power, the more dangerous the abuse. True to form, some governments and NGOs are using supranational bureaucracies to unde


Debt-Relief Plan Gains Key Support At World Bank, IMF
Wall Street Journal - September 26, 2005
Michael M. Phillips, michael.phillips@wsj.com
WASHINGTON -- Culminating more than a year of effort by the U.S., Britain and scores of antipoverty activists, the governors of the World Bank and International Monetary Fund endorsed a plan to forgive as much as $55 billion in loans to as many as 40 impoverished nations. The endorsements, during a series of weekend me


AIDS-Vaccine Test To Be Expanded On Upbeat Results
Wall Street Journal - September 23, 2005
Marilyn Chase, marilyn.chase@wsj.com
Researchers said clinical tests of an experimental AIDS vaccine from Merck & Co. are exceeding expectations, leading them to double enrollment in the trial to 3,000. The trial is being conducted in healthy volunteers to determine their immune response to the vaccine. The trial may indicate whether these immune reac


Vaccines That Keep Salmon Safe to Eat May Help Humans
Wall Street Journal - September 23, 2005
Scott Hensley, scott.hensley@wsj.com
Two DNA-based vaccines for animals have become the first to make it from the lab into commercial use, buoying hopes for similar vaccines for human diseases, such as Ebola, HIV/AIDS and SARS. One already has protected some salmon that could be headed for your dinner table soon. Fisheries scientists have known since the


Serono Discusses Settling Charges Over AIDS Drug
Wall Street Journal - September 22, 2005
David Armstrong, david.armstrong@wsj.com and Rachel Zimmerman, rachel.zimmerman@wsj.com
Parties in the federal and state investigation of Serono AG s marketing of AIDS drug Serostim are discussing an agreement under which the company or one of its units would admit wrongdoing and pay fines of about $700 million, say people familiar with the agreement. The settlement is close to being finalized and cou


Barefoot Doctors Make a Comeback In Rural China: Trained as a Nurse, Ms. Li Treats Datang Village; Delivering a Baby for $4
Wall Street Journal - September 22, 2005
Peter Wonacott, peter.wonacott@wsj.com
DATANG VILLAGE, China -- Shortly after Li Chunyan married five years ago, she sold her wedding gifts -- two water buffaloes -- and set up a tiny medical clinic next door to a pigpen. Her only competition in this hamlet with no running water was a witch doctor who treats patients by chanting and ringing bells. Villagers


Glaxo Halts Trial Of AIDS Drug Due to Liver Risks
Wall Street Journal - September 19, 2005
Marilyn Chase, marilyn.chase@wsj.com
GlaxoSmithKline PLC halted giving an experimental AIDS drug to newly diagnosed patients with human immunodeficiency virus after two of them developed severe liver toxicity. In a statement to the HIV patient community, Glaxo said data from safety and efficacy studies of the drug, aplaviroc, included reports of severe


Gates Charity Loses Health-Program Head
Wall Street Journal - September 13, 2005
SEATTLE -- Richard D. Klausner resigned as head of the Bill and Melinda Gates Foundation s Global Health Program effective at year end. Dr. Klausner, former director of the National Cancer Institute, a unit of the National Institutes of Health, served for the past 3½ years as top health officer overseeing programs in A


AIDS Pledges Leave a Funding Gap
Wall Street Journal - September 7, 2005
Michael M. Phillips, michael.phillips@wsj.com
With Europe in the lead, wealthy nations promised $3.7 billion to replenish the Global Fund to Fight AIDS, Tuberculosis and Malaria, sparking a feud over whether the U.S. is doing its share to combat diseases that together kill six million people a year. The pledges, made at a donors conference in London, fell well sho


U.N. Urges Africa to Address TB
Wall Street Journal - August 24, 2005
Marilyn Chase, Staff Reporter of The Wall Street Journal
World Health Organization tuberculosis experts are calling upon African health ministers gathering in Maputo, Mozambique , this week to declare a TB emergency on the continent. WHO, the health arm of the United Nations, estimates there are 2.4 million new tuberculosis cases globally each year and about


Copying West, Iraqi TV Station Creates Hits
Wall Street Journal - August 22, 2005
Yochi J. Dreazen, yochi.dreazen@wsj.com
BAGHDAD - Al-Jazeera became one of the first Arabic television networks to find a wide audience, playing up its political views and relying heavily on the gore and carnage of terrorism and war. Now, an upstart station here called Al-Sharqiya is trying to lure viewers from al-Jazeera and other emerging networks with a v


Panacos Drug May Combat Resistant AIDS Strains
Wall Street Journal - August 22, 2005
Marilyn Chase, Staff Reporter of The Wall Street Journal - August 22, 2005
Panacos Pharmaceuticals Inc. said a study showed its experimental AIDS drug PA-457 reduced blood levels of the human immunodeficiency virus by 90% in a small study of HIV-infected volunteers. PA-457 is the first member of a new class of antiviral drugs that block maturation of HIV, the virus that causes AIDS, by causin


As Universities Get Billions in Grants, Some See Abuses: Cornell Doctor Blows Whistle Over Use of Federal Funds, Alleging Phantom Studies: Defending a Star Professor
Wall Street Journal - August 16, 2005
Bernard Wysocki Jr., bernie.wysocki@wsj.com
NEW YORK -- Kyriakie Sarafoglou had only worked at Cornell University s medical school here for a few months when she says she suspected something was amiss. Cornell had received a five-year, $23 million grant from the National Institutes of Health for a center conducting studies of children s diseases. But several res


AIDS Group Sues U.S. Over Funds
Wall Street Journal - August 12, 2005
Michael M. Phillips, michael.phillips@wsj.com
WASHINGTON -- An American charity providing AIDS prevention services to prostitutes in poor countries sued the U.S. government for denying it federal grants because it refused to endorse the Bush administration s policy opposing prostitution. Washington-based DKT International, a nonprofit group that sold 390 million d


Whistle-Blowers Clash Over Splitting Award: AIDS Foundation's Dispute With Serono Ex-Employees May Delay Company's Pact
Wall Street Journal - August 4, 2005
David Armstrong, david.armstrong@wsj.com
An AIDS foundation is clashing with a group of former Serono SA employees over how to split a multimillion-dollar reward for informants in an expected settlement of a federal investigation of the drug maker. Swiss-based Serono has already set aside $725 million for the settlement, which would be one of the largest in a


Global Fund Hires Investigator
Wall Street Journal - August 3, 2005
Michael M. Phillips, michael.phillips@wsj.com
The Global Fund to Fight AIDS, Tuberculosis and Malaria asked an outside investigator to look into allegations of mismanagement at the multibillion-dollar institution. The allegations, brought by two Global Fund employees, include charges that officials issued contracts without following proper procedures, hired a midd


Bristol-Myers Squibb's Profit Nearly Doubles to $1 Billion
Wall Street Journal - July 29, 2005
Paul Davies at paul.davies@wsj.com
Bristol-Myers Squibb Co. s second-quarter earnings nearly doubled, helped by a small sales increase, favorable tax benefits and a favorable comparison with the year-earlier quarter, when it took a heftier charge for litigation expenses. The company also announced plans to launch a rheumatoid arthritis drug early next


Chinese Firm Joins Clinton AIDS-Drug Effort
Wall Street Journal - July 27, 2005
Marilyn Chase, marilyn.chase@wsj.com
The Clinton Foundation said it signed a deal with Mchem Pharma Group of Xiamen, China , to supply discounted chemical ingredients to producers of generic AIDS antiviral drugs in India and Africa. The agreement initially calls for Mchem to supply pharmaceutical intermediates and active pharmaceutical ingred


Beaded Lanyards, Cellphone Cases: Are Stars of Charity Chic
Wall Street Journal - July 15, 2005
Christopher Cooper, christopher.cooper@wsj.com
CAPE TOWN, South Africa -- In the heart of a sprawling slum on the outskirts of the city, first lady Laura Bush stood in a packed dayroom at a charity hospital and offered up a few remarks about women s empowerment. Though most of the audience followed her words with rapt attention, six women sitting at a table in the


Abbott Labs Lowers Brazil's Price For AIDS Drug, Ending Standoff
Wall Street Journal - July 11, 2005
Leila Abboud, leila.abboud@wsj.com
Abbott Laboratories said it will lower the price the government of Brazil pays for an important AIDS drug, ending a standoff that started when the country threatened to ignore patents and allow a state-run laboratory to make a generic copy. The agreement freezes the government s annual expenses for


REVIEW & OUTLOOK: Who's Stingy?
Wall Street Journal - July 6, 2005
Of all the earnest good intentions offered about African poverty in the lead-up to this week s G-8 summit in Gleneagles, Scotland, the most powerful wasn t from a concert stage accompanied by a guitar riff. It was President Bush s challenge to Europe regarding the farm subsidies that cripple African agriculture. In an


Study Says Circumcision Reduces AIDS Risk by 70%: Findings From South Africa May Offer Powerful Way To Cut HIV Transmission
Wall Street Journal- July 5, 2005
Mark Schoofs, mark.schoofs@wsj.com Sarah Lueck, sarah.lueck@wsj.com and Michael M. Phillips, michael.phillips@wsj.com
In a potentially major breakthrough in the campaign against AIDS, French and South African researchers have apparently found that male circumcision reduces by about 70% the risk that men will contract HIV through intercourse with infected women. Other than abstinence and safer sex, almost nothing has been proved to red


WHO Is Likely to Miss Its AIDS-Program Goal
Wall Street Journal - June 30, 2005
Gautam Naik, gautam.naik@wsj.com
LONDON - The World Health Organization acknowledged that it is unlikely to meet its goal of providing life-saving drugs to three million AIDS patients in poorer countries by year end, a sign of how difficult it is to stem the death toll of the disease. In a report released yesterday, the United Nations health agency sa


Grants Given for Freeze-Dried Vaccine, Nutritious Tuber
Wall Street Journal - June 28, 2005
Marilyn Chase, marilyn.chase@wsj.com
A program to conquer health problems of the poor is awarding rich grants for inventions such as hand-held diagnostics, drugs without resistance and needle-free vaccines that hold appeal for affluent countries, too. The awards, announced yesterday, are part of Grand Challenges in Global Health, a $436.6 million bonanza


Brazil Issues AIDS-Drug Ultimatum: Generic Production to Begin If Abbott Won't Lower Price; Bristol's African Initiative
Wall Street Journal - June 27, 2005
Matt Moffett, matthew.moffett@wsj.com and Heather Won Tesoriero, heather.tesoriero@wsj.com
Amid growing friction between Brazil and the U.S. over trade and AIDS policy, Brazil said Friday it was giving Abbott Laboratories 10 days to lower its price for the AIDS drug Kaletra . If Abbott refuses, Brazil said it would authorize a state-run laboratory to produc


Brazil Mulls Drug Patent Theft as an AIDS Antidote
Wall Street Journal - June 24, 2005
Mary Anastasia O'Grady
When the Bush administration offered Brazil $40 million for its anti-AIDS program earlier this year, Brasilia turned it down on principle. The terms of the deal required the government to condemn the sexual exploitation of women -- otherwise known as prostitution. Calling the U.S. demand theological, fundamentalist an


Glaxo, AIDS Group to Develop Vaccine Made From HIV Genes
Wall Street Journal - June 22, 2005
Marilyn Chase, marilyn.chase@wsj.com
In an effort to speed up the laggardly pace of AIDS vaccine development, GlaxoSmithKline PLC and the International AIDS Vaccine Initiative have struck a partnership to develop a vaccine made from HIV genes loaded inside a chimpanzee virus. Under the pact -- the first between the IAVI, a not-for-profit group, and a glob


Africa's Problems Move To Top of Global Agenda: Blair Seeks Debt Relief, Aid, But Bush Is More Cautious; Slow Change in Mozambique
Wall Street Journal - June 9, 2005
Roger Thurow, roger.thurow@wsj.com
Africa is moving to the forefront of the international agenda at a time when the continent is barely hanging on to the fringe of the global economy. Amid a global push for democracy and concern about terrorism and other ills bred by failed states, the continent is to be a central issue for top world leaders at a series


G-8 Negotiations On Debt Relief Pick Up Speed Hopes Are Raised for Deal On Increasing Assistance For Developing Nations
Wall Street Journal - June 9, 2005
Greg Hitt, greg.hitt@wsj.com
WASHINGTON -- One month before a pivotal summit of leaders of the Group of Eight leading nations, the pace of negotiations appears to be quickening toward providing debt relief to the world s poorest countries. The U.S. and U.K. moved closer to agreement this week on a plan to cancel about $34 billion in loans owed by


Drug-Resistant TB Hits New Group: Cases Among Immigrants Rise in U.S., Report Says; California Is Most Affected
The Wall Street Journal - June 8, 2005
Marilyn Chase, marilyn.chase@wsj.com
The face of tuberculosis that is resistant to drugs is changing in the U.S., researchers say. Increasingly, immigrants are the ones with the difficult-to-treat illness, reflecting a raging pandemic overseas, said the author of a report in the Journal of the American Medical Association today.


Shingles Vaccine Shows Promise: A One-Time Shot Significantly Reduces Chance Of Getting Painful Skin Condition, Study Says
Wall Street Journal - June 2, 2005
Barbara Martinez at barbara.martinez@wsj.com and Sylvia Pagan Westphal
A new vaccine is showing promise for preventing shingles, a painful, sometimes debilitating nerve and skin condition. Anyone who has ever had the chicken pox is at risk of getting shingles, which is caused by the reactivation of the chicken-pox virus. There has been no vaccine for the condition, which produces intensel


Coverage Issues: Many Ailments Can Pose Problems
Wall Street Journal - May 31, 2005
Sarah Lueck
Severe medical conditions like cancer, diabetes and HIV can pose formidable, and sometimes insurmountable, barriers to coverage in the individual insurance market. So can less severe health issues. For a 2001 study, Georgetown University s Institute for Health Care Research and Policy created seven hypothetical people


J&J Trumpets Its R&D Efforts Cancer, HIV Treatments Are Among 17 Medicines In Late Development Stages
Wall Street Journal - May 27, 2005
Scott Hensley, scott.hensley@wsj.com
In the first detailed review of its pharmaceutical pipeline in four years, Johnson & Johnson told analysts it is replenishing its portfolio of new drugs through improved research productivity, a slew of acquisitions and aggressive licensing. The maker of health-care products said it has 17 new medicines in advanced


Belgian Experiment: Make Prostitution Legal to Fight Its Ills - In Antwerp Area, Police Battle Crime, Human Trafficking; Outside, It Still Goes On - Villa Tinto's High-Tech Moves
Wall Street Journal - May 26, 2005
Dan Bilefsky, dan.bilefsky@wsj.com
ANTWERP, Belgium -- As the 9 a.m. shift began at Villa Tinto, which calls itself Europe s most high-tech brothel, prostitute Andrea Maes put on her leather boots, pressed her finger on a biometric scanner and started posing for potential clients in her neon-lit display window. After matching her fingerprint with the on


AIDS Scientists, Activists Fail to Fully Resolve Rift Over Trials
Wall Street Journal - May 24, 2005
Marilyn Chase, marilyn.chase@wsj.com
A meeting in Seattle between activists and researchers failed to fully resolve a rift that has disrupted some studies of a promising AIDS-prevention pill. The meeting found common ground on some issues that have arisen as AIDS treatments are being increasingly tested in developing nations, where the illness is causing


Panel Backs Boehringer Drug As Treatment for Resistant HIV: Advisers to FDA Conclude Urgent Need for Tipranavir Outweighs Safety Concerns
Wall Street Journal - May 20, 2005
Jennifer Corbett Dooren And Jeanne Whalen, Staff Reporters of THE WALL STREET JOURNAL
A Food and Drug Administration panel backed a new drug to treat HIV in patients who have become resistant to other drugs, despite safety concerns. The drug, tipranavir, made by a unit of German-based Boehringer Ingelheim GmbH, is a protease inhibitor aimed at blocking HIV replication. If tipranavir is approved, it woul


AIDS Researchers, Activists To Face Off Over Drug Studies
Wall Street Journal - May 18, 2005
Marilyn Chase, marilyn.chase@wsj.com
Drug-research sponsors, scientists and activists will face off in Seattle tomorrow, seeking to settle a conflict that has derailed tests of a promising AIDS prevention pill and threatens more shutdowns. The meeting, convened by the International AIDS Society, is a forum for finding common ground between protesters and


Gates Foundation Increases Grants for Health Research
Wall Street Journal - May 16, 2005
Marilyn Chase, marilyn.chase@wsj.com
Microsoft Corp. founder Bill Gates on Monday more than doubled his foundation s cash commitment to grants for scientists developing inventions to improve global health to $450 million from $200 million. The cash infusion goes to Grand Challenges in Global Health, a program launched in 2003 by the Seattle-based Bill and


Now That Chimeras Exist, What if Some Turn Out Too Human?
Wall Street Journal - May 6, 2005
Sharon Begley, sciencejournal@wsj.com.
If you had just created a mouse with human brain cells, one thing you wouldn t want to hear the little guy say is, Hi there, I m Mickey. Even worse, of course, would be something like, Get me out of this &%#!! body! It s been several millennia since Greek mythology dreamed up the chimera, a creature with the head o


Brazil Refuses U.S. AIDS Funds, Rejects Conditions
Wall Street Journal - May 2, 2005
Michael M. Phillips, michael.phillips@wsj.com and Matt Moffett, matthew.moffett@wsj.com
Brazil refused $40 million in American AIDS grants to protest the U.S. requirement that recipients first sign a pledge condemning prostitution. Brazil s decision escalates a global fight over the moral strings President Bush and his conservative allies in Congress attach to foreign assistance, especially when it come


Wolfowitz to Make Africa Top Priority Of the World Bank
Wall Street Journal - April 28, 2005
Greg Hitt, greg.hitt@wsj.com
WASHINGTON - Paul Wolfowitz said he intends to make Africa his top priority as president of the World Bank, saying the 184-nation institution can play a uniquely important role in overcoming the troubled continent s development challenges. I can t stress enough how important it is that the first priority of the bank is


Malaria Trial Could Set a Model For Financing of Costly Vaccines
Wall Street Journal - April 26, 2005
Marilyn Chase, marilyn.chase@wsj.com
Next month, hundreds of African infants will get an experimental vaccine against malaria in a medical trial that could foster a multibillion-dollar collaboration of science, philanthropy and market savvy. Under two new funding strategies championed by Microsoft Corp. founder Bill Gates and Britain s finance minister, G


What Ails Asia
Wall Street Journal - April 22, 2005
Kevin Voigt, kevin.voigt@awsj.com
Standing in the intensive care unit of the Singapore General Hospital, Dr. Koh Woon Puay said a final goodbye to her husband. Tears filling her goggles, she told the two doctors performing CPR on her husband to stop. His heart rate flat-lined; an alarm pierced through the room. A doctor switched it off. Her husband, Dr


Doctors, Hospitals Act To Safeguard Medical Data: Today is Federal Deadline For Stepped-Up Security; Compliance Costs Are High
Wall Street Journal - April 21, 2005
Christopher Conkey, christopher.conkey@wsj.com
On April 1, employees entering the headquarters of Blue Cross Blue Shield of North Carolina were handed fortune cookies with a message inside: Do the right thing: support security. The cookies were part of a campaign taking place across the health-care landscape to beef up security for confidential health information.


RJL Sciences and Its President Plead Guilty in Medical-Device Case
Wall Street Journal - April 20, 2005
William M. Bulkeley, bill.bulkeley@wsj.com
BOSTON - A small Michigan maker of medical devices and its president pleaded guilty in U.S. district court in Boston to conspiring with others to sell devices designed to promote diagnoses of AIDS wasting and to increase sales of an AIDS-wasting drug. The Justice department said RJL Sciences Inc., Clinton Township, Mic


Panel Suggests A 'Peace Corps' To Fight AIDS
Wall Street Journal - April 20, 2005
Marilyn Chase, marilyn.chase@wsj.com
To fill the yawning doctor gap in many AIDS-stricken countries, a medical advisory board is calling for the creation of an AIDS Peace Corps to send U.S. doctors, nurses, pharmacists and other health-care workers abroad to treat patients and train caregivers. Access to cheap generic AIDS drugs has exploded in recent yea


In Choosing Pope, Church Stakes Future on Its Base: German Cardinal Ratzinger, Now Benedict XVI, Is a Champion of Doctrine: A Life Combating Secularism
Wall Street Journal - April 20, 2005
Gabriel Kahn and Alessandra Galloni in Vatican City, David Luhnow in Mexico City and Matthew Karnitschnig in Vienna
The election as pope of Cardinal Joseph Ratzinger, a 78-year-old German theologian who once jokingly referred to his reputation as the Vatican s grand inquisitor, signals the Roman Catholic Church will march, not tiptoe, down the traditionalist path blazed by the late John Paul II. In his two-decade career as John Paul


Former Serono Executives Indicted in Kickback Scheme
Wall Street Journal - April 14, 2005
Rachel Zimmerman, rachel.zimmerman@wsj.com
BOSTON -- Four former top executives at drug maker Serono Inc. were indicted today by a federal grand jury for offering kickbacks to doctors in exchange for writing prescriptions for an AIDS drug marketed by the company. The U.S. Attorney here announced the criminal conspiracy charges against former sales and marketing


Human Enzyme Can Block HIV
Wall Street Journal - April 14, 2005
Marilyn Chase, marilyn.chase@wsj.com
Researchers have found out why a natural antiviral shield against HIV, found in human cells, sometimes works and at other times doesn t block the virus that causes AIDS. The finding could become the focus of a hunt for new drug therapies. The shield is an enzyme called A3G (short for APOBEC3G). A small version of this


Clinton Foundation to Provide AIDS Drugs to World's Children
Wall Street Journal - April 12, 2005
Marilyn Chase, marilyn.chase@wsj.com
Former President Bill Clinton s foundation is extending its reach in AIDS drug access with a $10 million initiative targeting children and the rural poor. Generic drug maker Cipla Ltd., of Mumbai, India , will supply the drugs at more than a 50% discount. Prices weren t disclosed because, Mr.


India Senses Patent Appeal: Local Companies Envision Benefits in Stronger Protections
Wall Street Journal - April 11, 2005
Eric Bellman, eric.bellman@awsj.com
BOMBAY, India - Behind India s new patent protections -- which raised alarms in some quarters -- is a quiet change in the country s industry: India is becoming an intellectual-property powerhouse. The amendments to India s patent law have sparked worries that Indian companies will face chilling global competition, and


'Advance-Purchase Contracts' Could Be Cure for Vaccine Sellers
Wall Street Journal - April 7, 2005
Marilyn Chase at marilyn.chase@wsj.com
A Washington think tank says it has a treatment for market failure in the vaccine sector, which could give both patients and the industry a shot in the arm. Pharmaceutical companies that fled the high-risk, low-margin vaccine field could be lured back with advance purchase contracts, according to a report scheduled to


China Enlists Companies, NGOs in AIDS Fight
Wall Street Journal - March 21, 2005
Matt Pottinger, matt.pottinger@wsj.com
BEIJING - The Chinese government is urging companies and non-governmental organizations to play a larger role in halting the spread of AIDS , underscoring a heightened sense of urgency about a national epidemic that Beijing had sought to play down until recently. Combating AIDS isn t just a government obligation, but a


AIDS Fight in Poor Nations Faces Financial Gap, Logistical Woes
Wall Street Journal - March 10, 2005
Gautam Naik at gautam.naik@wsj.com
LONDON - The fight against HIV and AIDS in developing countries faces a funding shortfall of more than $8 billion over the next three years and the additional challenge of getting key Western donors to coordinate their projects, officials leading the effort said. But even spending all available funds will be a challeng


Demand for Two AIDS Treatments Could Soon Exceed Supply
Wall Street Journal - March 4, 2005
Paul Davies, Staff Reporter of The Wall Street Journal
A rapid increase in purchases by two big AIDS-relief programs is stretching supplies of two treatments and will likely lead to shortages of the drugs for patients in developing countries, relief officials say. Bristol-Myers Squibb Co., which makes both drugs, and Merck & Co. , which markets one o


Madison Avenue Approach Helps Nonprofit
Wall Street Journal - March 3, 2005
David Wessel at capital@wsj.com
Population Services International seems to be a nonprofit that market-loving, results-oriented, compassionate people would love. It buys products -- water-purification tablets, antimalarial mosquito netting, AIDS tests and condoms -- on the open market. It sells them at deep discounts to poor people in 70 developing co


AIDS Vaccine 'Not Around Corner'
Wall Street Journal - March 3, 2005
Gautam Naik at gautam.naik@wsj.com
Bill Gates s health foundation s overriding goal is to fund the development of an AIDS vaccine, but the Microsoft Corp. founder says it will take more than a decade to get there -- a longer period than others had previously predicted. An AIDS vaccine is not around the corner, Mr. Gates told journalists in London on his


Are Too Many Unproven Drugs Receiving FDA Early Approval? Process Comes Under Scrutiny
Wall Street Journal - March 1, 2005
Anna Wilde Mathews and John Hechinger, anna.mathews@wsj.com and John Hechinger at john.hechinger@wsj.com
With the Food and Drug Administration s handling of drug safety already under a microscope, the suspension of multiple-sclerosis drug Tysabri creates a new area for scrutiny: the agency s process for rushing out promising new treatments for the most serious conditions. Biogen Idec Inc. and Elan Corp. yesterday announce


AIDS Scientists Cite Modest Gains - Some Drugs Hold Promise Amid Effort by Researchers To Improve Treatments
Wall Street Journal - February 28, 2005
Marilyn Chase, Staff Reporter
BOSTON -- AIDS researchers, seeking to steer clear of problems like drug resistance and toxicity, presented modest strides in developing better treatments at the 12th Annual Retrovirus Conference. Tibotec Pharmaceuticals, a unit of Johnson & Johnson , of New Brunswick, N.J., will enlarge studies of its compound TMC


Bush Ties Money For AIDS Work To a Policy Pledge
Wall Street Journal - February 28, 2005
Michael M. Phillips, Staff Reporter
WASHINGTON -- The Bush administration is barring private American AIDS organizations from winning federal grants to provide health services overseas unless they pledge their opposition to prostitution, as part of a broader Republican effort in recent weeks to apply conservative values to foreign-assistance programs.


Glaxo Drug Quickly Suppresses HIV in a Human Clinical Trial
Wall Street Journal - February 25, 2005
Marilyn Chase at marilyn.chase@wsj.com
BOSTON - Researchers at the 12th Annual Retrovirus Conference presented news of a promising new AIDS drug, and debated the details of drug-resistant AIDS in a New York man. A U.S.-based researcher working for GlaxoSmithKline PLC of London offered data from a human clinical trial of the company s experimental antiviral


Indian Doctor Is Matchmaker For HIV Singles
Wall Street Journal - February 24, 2005
Marilyn Chase at marilyn.chase@wsj.com
Caste and beauty are classic considerations for hopefuls in India s marriage market. Increasingly, so is HIV , the virus that causes AIDS. In India, where 5.1 million people are infected with the virus, the disease s powerful stigma typically forces young men and women to keep their HIV status secret. Yet they also fee


AIDS Drug Cocktails May Double Heart Risk
Wall Street Journal - February 24, 2005
Marilyn Chase at marilyn.chase@wsj.com
BOSTON - Potent drug cocktails keep AIDS patients alive, but may also cause a doubling of heart attacks, a risk on a par with smoking cigarettes. Jens Lundgren, a researcher at the University of Copenhagen, reported 277 heart attacks among 23,441 AIDS patients whose median age was 39. Dr. Lundgren presented his study a


Resistance Worries AIDS Parley: Drug Developers Encounter Tough Going Staying Ahead Of Fast-Mutating Virus
Wall Street Journal - February 23, 2005
Marilyn Chase, marilyn.chase@wsj.com
BOSTON - The breadth and depth of AIDS drug resistance is taxing the ability of drug developers to stay a step ahead of the epidemic, researchers said at the 12th Annual Retrovirus Conference here. In particular, scientists are concerned about patients whose initial HIV infection is a drug-resistant strain, since their


Bristol-Myers to Be Asked To Pull Drug Ads
Wall Street Journal - February 17, 2005
The AIDS Healthcare Foundation, the largest nonprofit provider of HIV/AIDS medical care in the U.S., said it will ask Bristol-Myers Squibb Co. to stop running advertisements for AIDS drug Reyataz, which it says minimize the seriousness of the disease. The ads, which read, The Word on HIV : Fight HIV Your Way, show two


What Makes a Drug Too Risky? There's No Easy Answer
Wall Street Journal - February 16, 2005
Ron Winslow at ron.winslow@wsj.com
Few people are caught more tightly in the vortex of the controversy swirling over drug safety than Debby Demaree and her family. Her three teenage children take Adderall, the attention-deficit drug Canadian regulators banned from the market there last week. Her son also takes Accutane, an effective acne medicine that i


Viacom Seeks to Rejigger AIDS Ads: Warning of Virulent Strain Prods Campaign to Reflect The New Challenges of HIV
Wall Street Journal - February 16, 2005
Christopher Windham at christopher.windham@wsj.com
The announcement last week of a rare and potentially virulent strain of HIV showed that the virus that causes AIDS remains an elusive and dangerous enemy. With that in mind, Viacom is weighing changes to a public-awareness campaign aimed at encouraging HIV testing and reducing the stigma of the disease. The campaign, c


Doctor Defends HIV-Strain Warning
Wall Street Journal - February 16, 2005
Marilyn Chase at marilyn.chase@wsj.com
Researcher David Ho defended his warnings of a dangerous new variant of the AIDS virus against critics who charged his report was premature and alarmist. Dr. Ho, head of the Aaron Diamond AIDS Research Center in New York, alerted New York public-health officials about a patient who was infected with a highly drug-resis


Medical Marijuana Gets Backing In Canada, Mouth Spray Wins Preliminary Approval; U.K. and U.S. Tests Loom
Wall Street Journal - February 8, 2005
Jeanne Whalen at jeanne.whalen@wsj.com
As some popular painkillers come under fire for causing dangerous side effects, an often-shunned alternative is gaining legitimacy in pain relief: cannabis. Medical marijuana has been winning legal endorsement through the efforts of a British pharmaceutical firm. GW Pharmaceuticals of Salisbury, England, has spent year


AIDS-Preventative Test Halted By Cameroon Amid Protests
Wall Street Journal - February 8, 2005
Marilyn Chase at marilyn.chase@wsj.com
A study of a promising AIDS-prevention pill was halted by the government of Cameroon after French AIDS activists charged that volunteers got too little information and care for their participation. Prospects for AIDS prevention-in-a-pill have captured scientific and public interest because a vaccine is thought to be at


REVIEW & OUTLOOK: Medicaid Rx
Wall Street Journal - February 2, 2005
All 50 states agree: Medicaid, the federal-state partnership to provide health care for the poor, is a fiscal and moral mess. The question is, what are our politicians going to do about it? By far the most promising answer to date comes from Florida, where Governor Jeb Bush is proposing a radical restructuring of the p


Promises in State of the Union Sometimes Fly, Sometimes Flop: Success, Failure Depend in Large Part On Congress, Elections, Priority Shifts
Wall Street Journal - January 31, 2005
Tim Annett
Presidents are constitutionally required to deliver to Congress their appraisal of the nation s health and well-being once a year. But the State of the Union address is rarely a mere survey of current conditions. It has become a president s primary device for laying out his agenda to the American people. President Bush


Hollywood Goes to Davos: Celebrities Attend World Economic Forum and, in Some Cases, Steal the Show
Wall Street Journal - January 31, 2005
Alan Friedman, Staff Reporter of the Wall Street Journal
DAVOS, Switzerland -- At times last week, the normally staid World Economic Forum annual meeting resembled a Hollywood movie opening or a rock concert. A nightcap to meet the stars on Friday night was quickly booked solid. I m in trouble, says former Serbian Finance Minister Bozidar Djelic after seeing he had reached t


Blair Praises Bush's Efforts To Promote Democracy: White House Foreign Policy And Calls to End Tyranny Receive Staunch Support
Wall Street Journal - January 27, 2005
Marc Champion at marc.champion@wsj.com, Frederick Kempe at fred.kempe@wsj.com and Roger Thurow at roger.thurow@wsj.com
DAVOS, Switzerland - President Bush still has his closest ally as he heads into his second term. Speaking to an audience of global elites, British Prime Minister Tony Blair fiercely defended Mr. Bush s inaugural call to end global tyranny and promote democracy. He said in an interview afterward that people have not ma


Bush Falls Behind on Promises For Antipoverty, AIDS Funding
Wall Street Journal - January 27, 2005
Michael M. Phillips at michael.phillips@wsj.com
WASHINGTON -- Even as he pledges significant aid for the victims of the Indian Ocean tsunami, President Bush is falling further and further behind on promises to boost funding to combat poverty in the developing world. The president quietly notified the Millennium Challenge Corp., a newly created foreign-aid agency, th


More AIDS Drugs Get to the Poor
Wall Street Journal - January 27, 2005
Gautam Naik at gautam.naik@wsj.com
The U.S. government and major health agencies reported encouraging results in the global push to provide antiviral drugs to desperately sick AIDS patients in developing countries, allaying earlier fears that key targets wouldn t be met. Officials from the U.S. government, the United Nations and the Global Fund to Fight


Chow Lays Out WHO Plan To Take On HIV , Malaria, TB
Wall Street Journal - January 25, 2005
Mali Fleming at mali.fleming@wsj.com
For many people infected with HIV/AIDS, tuberculosis and malaria living in developing countries, there are often no drugs and no viable health systems to treat their illnesses. As a result, about six million people world-wide die of these three diseases a year. The diseases are stunting economies and destabilizing comm


Merck Plans to Start Phase II Of AIDS-Vaccine Human Trials: Scientists to Test Prototype Deemed Most Promising For Safety, Effectiveness
Wall Street Journal - January 25, 2005
Marilyn Chase at marilyn.chase@wsj.com
Merck & Co. said it is launching the second phase of human trials on an AIDS vaccine that scientists called the most promising of its kind. The prototype AIDS vaccine will be tested in 1,500 people in the U.S., Canada , Australia , Latin America and the Caribbean.


U.S. Backs Limited Use Of Emergency HIV Regimen
Wall Street Journal - January 20, 2005
Betsy McKay at betsy.mckay@wsj.com
ATLANTA -- The U.S. government, in a long-awaited move, recommended that people exposed to the AIDS virus through rape, occasional unsafe sex and rare accidents be offered emergency drug treatment to prevent infection, but warned that the medication shouldn t be viewed as a morning-after pill for HIV. The guidelines, d


Monkey Gene May Yield - New Treatment for AIDS
Wall Street Journal - January 12, 2005
Scientists may have discovered an important new clue about why AIDS took root among humans, according to the British Broadcasting Corp.1, and it could lead to new treatments. What researchers in Britain discovered was a specific difference between a gene possessed by rhesus monkeys that is able to block HIV infection a


Europeans Trust Kofi Annan On Millennium Goals, Poll Finds
Wall Street Journal - January 7, 2005
U.N. Secretary General Kofi Annan is considered the person most trusted to provide information about the United Nations Millennium Development Goals, according to a recent Harris Interactive survey conducted in the U.S. and in three large European countries. Mr. Annan topped the lists in France and


Not-for-Profits Tread Carefully Charitable Organizations Not Part of Tsunami Relief Worry About Fund Raising
Wall Street Journal - January 6, 2005
Elizabeth Bernstein at elizabeth.bernstein@wsj.com and Rachel Emma Silverman at rachel.silverman@wsj.com
Even as Americans demonstrate immense generosity in helping the victims of the tsunamis in South and Southeast Asia, some not-for-profit organizations with no connection to the relief effort are worried that their donations will suffer as people redirect funds to the current crisis. Since Dec. 26, some $200 million has


Mothers Who Share Breast Milk: Internet Fuels Movement Aimed at Supplying Moms Unable to Nurse on Their Own
Wall Street Journal - January 4, 2005
Sara Schaefer Munoz, Staff Reporter of the Wall Street Journal
Amid mounting evidence of the health benefits of breast-feeding for infants, a movement is quietly growing among parents: sharing or even selling breast milk. The idea is to provide milk for adoptive mothers and women who cannot nurse because of illness or some other reason. Instead of turning solely to infant formula



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