2004

Making $5,000 Count
Wall Street Journal - December 31, 2004
Elizabeth Bernstein, elizabeth.bernstein@wsj.com
In the past few weeks, Gail Werner-Robertson has been contacted for donations by about 80 charities, from the Salvation Army to a local family-services group and a Ronald McDonald House -- and that was before groups started seeking relief funds for last Sunday s devastating tsunami. Though Ms. Werner-Robertson thought


FDA Approves First In a New Class of Pain Drugs
Wall Street Journal - December 29, 2004
Sara Schaefer-Munoz, Staff Reporter of The Wall Street Journal
Federal regulators approved the first in a new class of drugs for treating patients suffering from severe, chronic pain who don t get relief from other painkillers. Prialt, generically called ziconotide, is a synthetic version of sea snail venom manufactured by the Irish drug-maker Elan Corp. Approved for sale in the U


Death by Environmentalist
Wall Street Journal - December 29, 2004
Aid workers tending to the ravaged islands and coastlines of southern Asia say a big concern is an outbreak of malaria and other waterborne diseases in the aftermath of Sunday s tsunami. Which reminds us of a just-out World Health Organization report anticipating a shortage in a key antimalarial drug for next year.


WHO Warns of Severe Shortfall Of Supplies of Key Malaria Drug
Wall Street Journal - December 23, 2004
Gautam Naik at gautam.naik@wsj.com
LONDON - The World Health Organization warned that a vital antimalarial drug will be in short supply next year, potentially making it harder to treat patients who would otherwise have received treatment. The drug, known as Coartem and made only by Novartis AG of Switzerland , is the only effective


As Drug Titans Falter, Midsize Rivals Gain Cost Cuts, Narrower Focus Help Smaller Competitors Like Schering, Elan, Shire
Wall Street Journal - December 22, 2004
Jeanne Whalen at jeanne.whalen@wsj.com
LONDON - While big pharmaceutical companies on both sides of the Atlantic suffer product failures and a dearth of innovation, a clutch of midsize drug makers has quietly been seeing better fortune. Thanks to cost-cutting programs and a narrow focus on a few therapeutic areas, companies such as Ireland s Elan Corp., Sch


U.S., Others Add to AIDS Fund
Wall Street Journal - December 17, 2004
GENEVA - The Global Fund to Fight AIDS , Tuberculosis and Malaria said a just-released donation of $32 million from the U.S. and $66 million from other donors will bring estimated 2004 income to $1.56 billion, up from $936 million in 2003. The fund is an international partnership of 45 governments and private donors, i


Nonprofit Drug Company Gets Gates Grant to Target Malaria
Wall Street Journal - December 13, 2004
Marilyn Chase at marilyn.chase@wsj.com
SAN FRANCISCO - The Institute for OneWorld Health, a nonprofit drug company, announced today that it has received a five-year, $42.6 million grant from the Bill and Melinda Gates Foundation to develop a more affordable and accessible version of the world s leading drug for treating malaria. Malaria ranks as the world s


Deadly Medicine
Wall Street Journal - December 9, 2004
Carol Adelman
The World Health Organization and Doctors Without Borders, both headquartered in Geneva, have saved many lives. But they have endangered almost as many with their strategy of using unproven and outmoded drugs in developing nations to combat AIDS and malaria. These AIDS drugs are cheaper and, like European generic drugs


Beware the Moral Cops
Wall Street Journal - December 2, 2004
Albert R. Hunt, al.hunt@wsj.com.
There is some important good news for which Republicans and Democrats alike can share credit: The teen birth and pregnancy rate in America has plummeted over the past decade. Last year there were 41.7 births per 1,000 kids between the ages of 15 and 19, down dramatically from 61.8 in 1991, the U.S. Centers for Disease


Global HIV Infections Keep Rising; Women Increasingly Fall Victim
Wall Street Journal - November 24, 2004
Marilyn Chase, marilyn.chase@wsj.com
The ranks of people with HIV/AIDS around the world rose to a record 39.4 million in 2004, according to a new estimate, up 7.7% from an adjusted 36.6 million two years ago. About 3.1 million died of AIDS and 4.9 million adults and children became infected with HIV , the human immunodeficiency virus, world-wide in 2004.


Drug Companies Look to China For Cheap R&D
Wall Street Journal - November 22, 2004
Laura Santini, laura.santini@wsj.com
SHANGHAI -- Long known as a place to produce clothes and toys cheaply, China now is providing the West with another opportunity: developing drugs at lower cost. Opening a new frontier in outsourcing, pharmaceutical companies overwhelmed by the rising cost of creating drugs are turning to China to conduct research and d


Global AIDS Fund To Delay Grants To Raise Money
Wall Street Journal - November 19, 2004
Marilyn Chase,marilyn.chase@wsj.com
Amid U.S. pressure to slow its pace of doling out money, the Global Fund to Fight AIDS , Tuberculosis and Malaria voted to delay offering new grants until March. The Global Fund wanted to launch its 2005 grant cycle this month, but faced U.S. lobbying of its board, donors and recipients to improve finances and manageme


FDA Official Assails Agency On Monitoring of Risks At Hearing on Vioxx Recall, Safety Expert Cites Lapses, And Points to Other Drugs
Wall Street Journal - November 19, 2004
Anna Wilde Mathews at anna.mathews@wsj.com and Heather Won Tesoriero at heather.tesoriero@wsj.com
WASHINGTON - A debate over how the Food and Drug Administration responds to newly discovered risks in drugs escalated yesterday, as an FDA official criticized his agency s approach and raised concerns about a handful of medications already on the market. David Graham, associate director for science and medicine in the


Birth of a Biotech Industry: Western Drug Makers Outsource R&D To Scientists in Shanghai and Beijing
Wall Street Journal - November 19, 2004
Laura Santini, laura.santini@wsj.com
SHANGHAI, China - Known for producing low-cost clothes and well-priced toys, China is getting into making inexpensive drugs. Opening a new frontier of outsourcing, global pharmaceutical companies overwhelmed by the rising costs of producing new drugs increasingly are turning to China to conduct low-cost research and de


As Teen Births Drop, Experts Are Asking Why
Wall Street Journal - November 17, 2004
Betsy McKay at betsy.mckay@wsj.com and Ann Carrns at ann.carrns@wsj.com
It looked like an uphill battle when the National Campaign to Prevent Teen Pregnancy set a goal in 1996 of cutting the teen-pregnancy rate by one-third by 2005. Teens accounted for about one million pregnancies a year, most of them unplanned. And taxpayers were paying as much as $20 billion a year to financially suppor


New Environments Ex-Activists Find Grass Is Greener On Corporate Side
Wall Street Journal - November 17, 2004
Deborah Ball at deborah.ball@wsj.com
-- Mr. Burke Once Fought Mines; Now He Pushes Big Dig Near Madagascar Town -- Birdwatching for Executives FORT DAUPHIN, Madagascar -- Thirty years ago, Tom Burke helped organize demonstrations against Rio Tinto PLC s plans to mine copper in a national park in Wales. Within months, Rio Tinto scrapped its plans. Sinc


U.S. Urges Delay In Health Grants From Global Fund
Wall Street Journal - November 17, 2004
Marilyn Chase at marilyn.chase@wsj.com
The U.S. is lobbying to block the proposed launch this week of a new round of grants by the Global Fund to Fight AIDS, Tuberculosis and Malaria, a United Nations-backed international health group that has funded $8 billion of projects in 130 countries through pledges from wealthy countries and foundations. Exerting its


Gaps Between Brazil, U.S. Threaten Trade Talks
Wall Street Journal - November 16, 2004
Geraldo Samor, geraldo.samor@wsj.com
BRASILIA - Brazil s foreign minister said the future of a hemispherewide free-trade zone is in peril, largely because the U.S. is pushing a reluctant Brazil to overhaul our entire economic framework. Large gaps remain between the U.S. and Brazil, the two main protagonists in the effort to create the Free Trade Area of


How Drug's Rebirth as Treatment For Cancer Fueled Price Rises: Once-Demonized Thalidomide Boosts Celgene's Sales; Patients See Costs Soar
Wall Street Journal - November 15, 2004
Geeta Anand, geeta.anand@wsj.com
-- Avoiding AIDS Activists WARREN, N.J. - When Celgene Corp. got its first drug approved, it priced a 50-milligram capsule at $6. Today, it sells the same white capsule for nearly five times the original price, or $29. Little has changed to affect the cost of making the drug since it was first sold in 1998 as a treatme


Generic Maker Pulls HIV Drugs From WHO Use
Wall Street Journal - November 10, 2004
Jeanne Whalen at jeanne.whalen@wsj.com and Leila Abboud at leila.abboud@wsj.com
In a setback for efforts to combat HIV in the developing world, India s largest pharmaceutical maker has withdrawn all its generic HIV treatments from a list recommended by the World Health Organization , saying it can t be sure the drugs are exact replicas of patented treatments they seek to copy, according to the WHO


New Vision-Loss Drugs Offer Hope
The Wall Street Journal - November 9, 2004
Rhonda L. Rundle at rhonda.rundle@wsj.com
The good news for seniors suffering vision loss caused by macular degeneration is that several new drug treatments are on the horizon. The bad news is that prospects remain dim for a cure anytime soon. Macular degeneration affects roughly a third of people over age 75 and is the leading cause of blindness in the elderl


The Grant Giver
The Wall Street Journal - November 8, 2004
Marilyn Chase
-- 1. Patty Stonesifer President and Co-Chairman, Bill and Melinda Gates Foundation What a difference a decade makes. Back in the heady 1990s, Patty Stonesifer was leading Microsoft Corp. s interactive-media group, launching new software, and demonstrating for a reporter a new videogame with her trademark brio, saying,


Super Bugs, Bird Flu Worry Experts
Wall Street Journal - November 1, 2004
Marilyn Chase, Staff Reporter of The Wall Street Journal
Infectious-disease experts are calling for global surveillance and greater investment to fight what they called a shadow epidemic of drug-resistant diseases. Researchers, at a conference in Washington, said resistant versions of germs such as klebsiella and pseudomonas are making hospital infections harder and costlier


U.S. Pays High Prices For Global AIDS Drugs, Study Says
Wall Street Journal - October 29, 2004
Sarah Lueck, Staff Reporter
The U.S. government is paying twice as much for many of the drugs in its global AIDS program as other international aid organizations are, because the Bush administration won t buy cheaper versions made in India , congressional investigators found. A draft report by the Government Accountability Office -- the first


Novartis Sets Deal to Seek New Drugs for Fighting TB
Wall Street Journal - October 27, 2004
Marilyn Chase, Staff Reporter of The Wall Street Journal
The Global Alliance for TB Drug Development plans to team up with a unit of Novartis AG to speed development of much-needed new drugs to treat tuberculosis . Tuberculosis, the world s second-biggest killer, after AIDS, infects one-third of the world s population. It causes nine million new cases of active disease and k


Canadians Fear Pressure in U.S. For Drug Imports
Wall Street Journal - October 19, 2004
Christopher J. Chipello, chris.chipello@wsj.com
MONTREAL - Growing political pressure in the U.S. for freer imports of low-price drugs from Canada is increasing concern among Canadians that the cross-border trade will lead to drug shortages or higher prices up north. A group of Canadian health-lobby organizations representing patients, senior citizens and pharmacist


Malaria Vaccine For Children Makes Strides: Glaxo Treatment Reduces Severe Attacks 58% in Study; Broad Use Is Years Away
Wall Street Journal - October 15, 2004
Marilyn Chase, marilyn.chase@wsj.com
Researchers took a big step toward a malaria vaccine by showing they can reduce cases of life-threatening malaria in children by more than half and milder attacks by almost a third. Doctors from Africa, Spain and GlaxoSmithKline PLC s biologicals unit in Belgium said a Glaxo vaccin


A New Agenda for South Africa: Mbeki's Detailed Plan Aims to Enrich Lives At Home, Stature Abroad
Wall Street Journal - October 12, 2004
Mark Schoofs, mark.schoofs@wsj.com
JOHANNESBERG, South Africa - Backed by a mandate from nearly 70% of voters, South African President Thabo Mbeki is shifting his country from the sweeping politics of revolution and racial reconciliation to the nuts-and-bolts politics of economics and government delivery. Mr. Mbeki s second-term agenda -- expanding publ


Net Benefits: Where men can turn to help close the gender gap in health
Wall Street Journal - October 11, 2004
Laura Landro, laura.landro@wsj.com
It isn t a man s world when it comes to health care. Men make only half as many visits to doctors as women do for preventive care, die almost six years younger than women, and are more likely to become victims of cancer, stroke, heart disease, depression and suicide. They also go online for health information less ofte


Have Donation, Will Travel
Wall Street Journal - October 1, 2004
Katherine Rosman, Staff Reporter of The Wall Street Journal
On a recent trip to Mexico , Kaki Hopkins flew on a private plane, stayed in an 18th-century inn and met her friends each evening for martinis and Chardonnay. But the real highlight of her stay was a luncheon with local women -- held in a cardboard-walled hut with a dirt floor and goats outside the door. Mrs. Hopk


Glaxo AIDS Drugs to Be Tested In Topical Form, as Microbicide
Wall Street Journal - September 24, 2004
Marilyn Chase, marilyn.chase@wsj.com
A nonprofit AIDS agency is set to announce a new corporate partnership to beef up its portfolio of antiviral AIDS gels aimed at protecting vulnerable women in the developing world. The International Partnership for Microbicides said it reached agreement with GlaxoSmithKline PLC to test several of Glaxo s proprietary AI


A Big Drug Maker Moves to Play Down Mass-Market Pills: Roche Seeks Pricey Products In Specialties Like Cancer And Rejects Megamergers: Pfizer's Edge in Sales Muscle
Wall Street Journal - September 20, 2004
Jeanne Whalen at jeanne.whalen@wsj.com
BASEL, Switzerland - In December 2001, Roche AG drug scout Hari Kumar packed his warmest parka and flew to Edmonton, Alberta, to chase down an experimental medicine called ISA247. Dr. Kumar had heard about it early that year at a medical conference, and every month he called the Canadians who were developing it to prop


Senate Panel Adds Over $3 Billion To Budget Bill: Bid to Block Overtime Rule Might Jeopardize Measure On Labor, Health, Schools
Wall Street Journal - September 16, 2004
David Rogers, david.rogers@wsj.com
The Senate Appropriations Committee approved a massive labor, health and education bill that adds more than $3 billion to President Bush s 2005 budget request while seeking to block the administration from implementing new overtime-wage rules opposed by organized labor. The action came as the Republican-controlled pane


AIDS Vaccine Disappoints in Tests: Experimental Drug Failed To Show Robust Response In Human Immune System
Wall Street Journal - September 3, 2004
Michael Waldholz, mike.waldholz@wsj.com
An experimental AIDS vaccine being tested in Africa and in the United Kingdom failed to produce a robust immune response, disappointing researchers and public-health officials who had been working on it for six years. At an AIDS-vaccine conference in Lausanne, Switzerland , a research team from the U


On Death and Dying
Wall Street Journal - August 31, 2004
Abraham Verghese
In the early years of the AIDS epidemic, when effective drug treatment was just a dream, many of us in the field of infectious diseases found that our work revolved to a large degree around the care of the dying. It was not something we had anticipated. In asking how I could best care for my patients who were dying (an


How Botswana Reads All About It
Wall Street Journal - August 23, 2004
Dan Morse, dan.morse@wsj.com
There are 5,500 writers and photographers covering the Olympics. The U.S. has 499. Britain has 230. From Botswana : one. She is Lucretia Chima, a 27-year-old sportswriter for the Botswana Daily News. You want her job? When writing broad stories about the Games, she must paint the broad picture herself. When writing spe


The Manchurian Multinational
Wall Street Journal - August 20, 2004
Bad enough that the summer re-make of The Manchurian Candidate recast a corporation in the villain s role played by Communism in the original. Now the World Alliance of Reformed Churches is signing on. Meeting in Ghana this month, the alliance, which represents 75 million Christians in 100 countries, claims that U.S.-s


Global Fund Is Coming Up Short U.S. May Withhold Some Donations Because Others Haven't Fulfilled Pledges
Wall Street Journal - August 19, 2004
Marilyn Chase, marilyn.chase@wsj.com
U.S. Global AIDS Coordinator Randall Tobias said Washington will hold back $120 million of this year s promised donations to the Global Fund To Fight AIDS, Tuberculosis and Malaria because other donors have failed to give their share. The U.S., the world s largest contributor to the Global Fund, earlier appropriated $5


Key AIDS Study In Cambodia Now in Jeopardy
Wall Street Journal - August 12, 2004
Marilyn Chase, at marilyn.chase@wsj.com and Gautam Naik at gautam.naik@wsj.com
A key human trial of a potentially pioneering drug for preventing HIV is in jeopardy in Cambodia after prostitutes targeted for the study there protested its proposed terms and government officials raised concerns. Although the government initially supported the trials, Cambodian Health Minister Nuth Sokjom said he has


Drug Cocktails Hit Psychiatry: In Largely Untested Method, Doctors Mix Several Medicines To Treat Some Mental Illness
Wall Street Journal - August 10, 2004
Leila Abboud, Staff Reporter of The Wall Street Journal
Psychiatrists are increasingly crafting drug cocktails of multiple medicines to treat depression, bipolar disorder and schizophrenia. The approach, called polypharmacy, aims to help people who don t respond to a single drug by putting them on several drugs that target different brain chemicals. The approach -- driven i


How a Hospital Works to Gain Trust of Blacks
Wall Street Journal - August 9, 2004
Christopher Windham, christopher.windham@wsj.com
BALTIMORE - The segregated wards and waiting rooms at prestigious Johns Hopkins University hospital weren t fully integrated until the 1970s. The university s medical school didn t admit blacks until the 1960s. Now Johns Hopkins needs the help of blacks in its surrounding East Baltimore neighborhood to meet federal rul


NIH Rejects Move Against Abbott: Agency Won't Force Firm To Cut Price of AIDS Drug Funded Partly by Taxpayers
Wall Street Journal - August 5, 2004
Leila Abboud , Staff Reporter of The Wall Street Journal
The federal government decided against forcing drug maker Abbott Laboratories to roll back a fivefold price increase on an AIDS drug developed in part with taxpayer money. (See Corrections & Amplifications item below.) Abbott, based in North Chicago, Ill., raised the price of a daily dosage of


FDA Approves a New Facial Filler: Cleared for Narrow Use, Product Is Likely to Be Used For Cosmetic Applications
Wall Street Journal - August 4, 2004
Jennifer Saranow and Amir Efrati, Staff Reporters of The Wall Street Journal
Some plastic surgeons may soon be adding an unofficial new weapon to their arsenal against aging. The U.S. Food and Drug Administration yesterday approved a new facial filler from Aventis SA. While the product, called Sculptra, has been approved only for the very narrow use of treating facial wasting associated with AI


Ranbaxy to Seek Speedy Approval For Its Combination AIDS Drug
Wall Street Journal - August 3, 2004
Sarah Lueck and David P. Hamilton, Staff Reporters of The Wall Street Journal
Indian drug maker Ranbaxy Laboratories Ltd. said it will apply for speedy approval from the Food and Drug Administration for its generic combination AIDS drug, raising the possibility that a U.S. global AIDS-treatment program might be able to distribute the product by next year. Meanwhile, the


Americans Say Better Access To AIDS Medicines Is Needed
Wall Street Journal - August 2, 2004
A Wall Street Journal Online News Roundup
Most Americans believe the HIV/AIDS epidemic is worsening and that far more can be done to provide patients with access to affordable medicines to treat the disease, according to a recent WSJ Online/Harris Interactive Health poll. At the 15th International AIDS Conference in Thailand last month, the United Nations


Vaccine Targets Global Strains of HIV
Wall Street Journal - July 29, 2004
Marilyn Chase, Staff Reporter of The Wall Street Journal
A biotech company said it launched a human safety study of a new AIDS vaccine that seeks to spark immunity against different strains of the virus found in different parts of world. GenVec Inc. of Gaithersburg, Md., said it is manufacturing the AIDS vaccine for human studies under a $30 million contract with the Nationa


Stem-Cell Research Is Used As Challenge to Bush on Science
Wall Street Journal - July 27, 2004
Bernard Wysocki Jr., Staff Reporter of The Wall Street Journal
Democrats, seizing on calls to expand federally funded stem-cell research, will put the issue in the spotlight of this year s presidential campaign tonight at the party s national convention. A high point will be a speech by Ron Reagan, son of the late President Reagan. The younger Mr. Reagan s presence at a Democratic


Gates to Donate Dividend Windfall To His Foundation
Wall Street Journal - July 21, 2004
Robert Frank and Ann Grimes, Staff Reporters of The Wall Street Journal
Only Bill Gates could call $3 billion a drop in the bucket. Mr. Gates announced yesterday that he is giving a projected $3.35 billion windfall from MicrosoftCorp. s one-time $3-a-share dividend to his private foundation. But not right away. Indeed, a spokesman for the Microsoft chairman indicated that the large dividen


Gates Contributes $50 Million To Help AIDS Fund Narrow Gap
The Wall Street Journal - July 16, 2004
Marilyn Chase, Staff Reporter
BANGKOK -- Addressing a major funding gap, the Bill and Melinda Gates Foundation said it will give a $50 million grant to the Global Fund to Fight AIDS, Tuberculosis and Malaria. Separately, doctors at the XV International AIDS Conference in Thailand urged pharmaceutical companies to provide at least two years of care


Trying to Arrest HIV's Spread: Officials Encouraged By Needle Exchange In China and Vietnam
Wall Street Journal - July 15, 2004
Gautam Naik, gautam.naik@wsj.com
BANGKOK, Thailand - Public-health workers around the world are closely watching the promising results of an innovative program in China and Vietnam that suggests the spread of the AIDS virus can be contained among intravenous-drug users -- a high-risk, hard-to-reach group that threatens to hasten the dis


In AIDS War, Newest Front Is Link to TB
Wall Street Journal - July 15, 2004
Marilyn Chase, marilyn.chase@wsj.com
BANGKOK, Thailand - More than one third of the planet s population carries tuberculosis , an often latent bacterial infection that haunts the developing world. While TB is an epidemic in its own right, its troubling relationship with AIDS is increasingly drawing the attention of public health researchers.


Museveni's ABCs
Wall Street Journal - July 14, 2004
Abstain from sex or delay having sex if you are young and not married, Be faithful to your sexual partner (zero-grazing), after testing, or use a Condom properly and consistently if you are going to move around. This has now been globally popularized as the ABC strategy . ---- Ugandan President Yoweri Museveni, in an


AIDS Agonistes
Wall Street Journal - July 14, 2004
Some things in life you can count on, alas. One is that when world leaders gather to talk about AIDS, Public Enemy Number One is the U.S. So it goes in Bangkok this week at the International AIDS Conference. Jacques Chirac demonstrated how little one Frenchman knows about sex when he effectively blamed the AIDS epidemi


Chirac: U.S. AIDS-Drug Stance Is 'Tantamount to Blackmail'
Wall Street Journal - July 13, 2004
Joseph Schuman, joseph.schuman@wsj.com
Differences over U.S. global AIDS policies risked provoking a new diplomatic feud today, as French President Jacques Chirac accused the Bush administration of unduly pressuring developing countries to give up the right to make generic HIV drugs. Joining a debate with echoes from the quarrels over


Lack of AIDS Doctors In Poor Countries Stalls Treatment
Wall Street Journal - July 13, 2004
Marilyn Chase, marilyn.chase@wsj.com and Amir Efrati, amir.efrati@dowjones.com
WANTED: Health-care workers who treat AIDS patients. Must like travel, long hours and scant pay. Your work may be halted because of a coup d etat. You will bury friends. You might save lives. These days, there is greater access than ever to cheap, generic AIDS drugs in the developing world. But a serious shortage of tr


WHO Misses AIDS-Treatment Goal
Wall Street Journal - July 12, 2004
Gautam Naik, Staff Reporter of The Wall Street Journal
LONDON - The World Health Organization said it missed its initial target to supply AIDS drugs to half a million patients in the first six months of 2004, a sign of the difficulties of distributing medicines in poorer countries. In December, the Geneva agency launched an ambitious program known as three-by-five to sup


In India, Stigma Of AIDS Curbs Control of HIV
Wall Street Journal - July 12, 2004
Joanna Slater, joanna.slater@wsj.com
KOTTIYUR, India -- One rainy day in June 2003, Rema T. Krishnan returned to this small town high in the lush green hills of southern India and began lying to her neighbors: Her husband, Shaji Kumar, she said, had succumbed to tuberculosis in a nearby hospital. The reality was more frightening.


As AIDS Spreads Slowly in Asia, So Does Inaction
Wall Street Journal - July 12, 2004
Marilyn Chase, marilyn.chase@wsj.com
BANGKOK - The late takeoff and slow growth of the AIDS epidemics in Asia offer no immunity against the virus but may lull leaders into a tepid response, scientists said yesterday at the opening of the XV International AIDS Conference. The slowly evolving epidemics of Asia are very dangerous, said Tim Brown, senior fell


China's Viagra Heist
Wall Street Journal - July 9, 2004
When Pfizer invented Viagra it thought it had a right to be richly rewarded for coming up with a product that would improve the lives of millions. And, more or less, that s the way it s worked out. But this week China decided to ignore market principles, its own World Trade Organization commitments and the long-term in


Wall of Fear Isolates HIV Carriers in India
Wall Street Journal - July 9, 2004
Joanna Slater, joanna.slater@wsj.com
KOTTIYUR, India -- One rainy day in June 2003, Rema T. Krishnan returned to this small town high in the lush green hills of southern India and began lying to her neighbors: Her husband, Shaji Kumar, she said, had succumbed to tuberculosis in a nearby hospital. The reality was more frightening.


New AIDS Drug Reduces Virus In Monkeys
Wall Street Journal - July 9, 2004
Amir Efrati, Staff Reporter of The Wall Street Journal
A long-sought way to attack the AIDS virus -- by blocking an enzyme called integrase that the virus uses to make copies of itself -- is finally gaining traction, and could provide a wave of AIDS therapies. In a study published today in Science, a Merck & Co. compound that blocks integrase was successful in rhesus m


HIV Infections Surged Last Year: AIDS Program Reports Five Million New Cases And Three Million Deaths
Wall Street Journal - July 7, 2004
Gautam Naik, gautam.naik@wsj.com
LONDON - Five million people last year were infected with HIV, the virus that causes AIDS -- the largest number in any single year since the epidemic began two decades ago, according to new data published by UNAIDS , an AIDS program sponsored by the United Nations and other groups. Despite a huge global push to figh


New Funds Are Making It Easier to Donate Abroad: Charities Set Up Vehicles To Vet Causes for Terrorist Ties While Preserving Tax Break
Wall Street Journal - July 6, 2004
Rachel Emma Silverman, rachel.silverman@wsj.com
Terrorism has made it trickier for international charities to be sure their money is winding up in the right hands. Now, they re offering donors some new reassurances. As the government heightens its scrutiny of charities that donate abroad, many are adopting tougher procedures to track the groups that receive their do


Gadhafi at Home
Wall Street Journal - July 6, 2004
Assistant Secretary of State William Burns announced from Tripoli last week that the U.S. had formally restored diplomatic relations with Libya after 24 years. With this gesture, the U.S. added the finishing touch to Moammar Gadhafi s journey from pariah to international acceptance. But while this new, peaceable Gadhaf


In New Trade Pacts, U.S. Seeks To Limit Reach of Generic Drugs
Wall Street Journal - July 6, 2004
Marilyn Chase, marilyn.chase@wsj.com and Sarah Lueck, sarah.lueck@wsj.com
As public-health groups urge wider use of generic drugs to lower the cost of treating AIDS and other diseases in developing countries, U.S. trade negotiators -- prodded by the drug industry -- are taking the opposite stance in new trade pacts, seeking to strengthen protections for costlier brand-name drugs. In a series


Pap Tests Not Always Needed
Wall Street Journal - July 6, 2004
By Robert J. Davis, Staff Reporter of The Wall Street Journal
or decades, conventional wisdom has held that nearly every woman needed a Pap test every year to prevent cervical cancer. Recent studies suggest many women and their doctors continue to believe the claim and act on it, even though leading medical organizations now say such frequent testing often isn t necessary and tha


Thailand Hosts AIDS Conference Hoping to Put Spotlight on Asia
Wall Street Journal - July 6, 2004
Marilyn Chase, marilyn.chase@wsj.com
As an expected 15,000 people begin arriving this week in Bangkok for the XV International AIDS Conference, Thailand plans an unusually frank display of its approach to AIDS and, in the process, hopes to draw world attention to the burgeoning epidemic sweeping through Asia. While stamping visitors passports, Thai offic


Study Shows HIV Continues To Spread Despite AIDS Effort: UNAIDS Data Suggest Global Push To Combat the Virus Isn't Working
Wall Street Journal - July 6, 2004
Gautam Naik, gautam.naik@wsj.com
LONDON - Despite a huge global push in recent years to fight HIV in developing countries, the virus continues to infect a growing number of people and claim millions of lives each year, according to new data published Tuesday by UNAIDS , an AIDS program sponsored by the United Nations and other groups. In its repor


Generic AIDS Pill Gets Acceptance Drug Made in India Costs: Less Than Brand Names; Study Covered Six Months
July 2, 2004 - Wall Street Journal
Marilyn Chase, marilyn.chase@wsj.com
An AIDS study has validated the safety and efficacy of a popular generic-drug regimen made in India , raising the stakes in the effort to provide affordable treatments to epidemic-ravaged Africa. In the first such study of a generic AIDS drug, published this week in the British journal the Lancet, researchers from Afri


Viral Strain: In AIDS Fight, Ambitious Goals Meet Hard Realities
Wall Street Journal - July 1, 2004
Gautam Naik, Mark Schoofs And Sarah Lueck, Staff Reporters of The Wall Street Journal
Millions of Ill in Poor Nations Fail to Get Drugs as Funds, Medical Systems Fall Short: Attention Shifts to Terror Four years ago, the United Nations, governments of wealthy countries and major foundations committed for the first time to bring drugs to the millions of AIDS sufferers in poor countries. No longer, it was


Glaxo to Remain Part of HIV Trial In Poor Countries
Wall Street Journal - July 1, 2004
Jeanne Whalen, jeanne.whalen@wsj.com
LONDON - GlaxoSmithKline PLC, under political pressure, said it will remain a participant in a major HIV trial in the developing world. Earlier, Glaxo, the world s second-biggest drug maker, had told researchers it was withdrawing, delaying the trial s start and throwing its future into doubt. That decision drew heat f


At Zimbabwe Clinic, Wait Is Long And U.S. Drug Cupboard Is Bare
Wall Street Journal - July 1, 2004
Mark Schoofs, mark.schoofs@wsj.com
BULAWAYO, Zimbabwe - On a recent morning at the Mpilo Chest Hospital here, four orphans, ages 10 to 13, held their medical folders and fidgeted. A nurse came by, bent down and told them they would get drugs for AIDS the following week. The program, operated by the Zimbabwean health ministry with help from the French gr


National Institutes of Health Is Under Fire: Longtime Favorite of Congress Grapples With Slim Funding Increases, Conflicts Inquiry
Wall Street Journal - June 22, 2004
Bernard Wysocki Jr., Staff Reporter of The Wall Street Journal
WASHINGTON - The National Institutes of Health, long a sacred cow in Washington, is coming under fire from the very Congress that once showered it with funds. After doubling its annual budget to $28 billion in the past five years, Congress has given NIH tiny increases this year, as large fiscal deficits force budget ti


The Risks of Mixing Drugs and Herbs: Recent Studies Pinpoint Range of Negative Interactions; Total Cereal and Antibiotics
Wall Street Journal - June 22, 2004
Jane Spencer, Staff Reporter of The Wall Street Journal
A wave of recent studies is sparking concern about the dangers of taking herbal supplements -- including St. John s Wort, echinacea and ginkgo biloba -- in combination with mainstream prescription drugs. For years, doctors have recognized that many herbal remedies have powerful pharmacological effects, and patients hav


Administration Limits Content Of AIDS Efforts Seeking Grants
The Wall Street Journal - June 21, 2004
Marilyn Chase, Staff Reporter
The Bush administration has tightened the reins on program content and condom discussions by AIDS prevention programs seeking federal grants. Regulations published in the Federal Register last week require review and approval of Web-site content of groups seeking grants from the Centers for Disease Control and Preventi


Researchers Report More Sensitive AIDS Test
Wall Street Journal - June 15, 2004
Marilyn Chase, marilyn.chase@wsj.com
A new technology to test for the AIDS virus may enable doctors to monitor patient treatment better and screen blood with greater speed and sensitivity. The new test detects tiny amounts of a protein called p24 inside the human immune-deficiency virus, said Niel Constantine of the Institute of Human Virology at the Univ


Bono Brings Star Power To Silicon Valley Fund
Wall Street - June 15, 2004
Robert A. Guth
Bono, lead singer for rock band U2 and antipoverty activist, is starting a new gig: media and entertainment investing. The 44-year-old rock star is joining Elevation Partners, a new Silicon Valley fund set up earlier this year by veteran technology investor Roger McNamee and John Riccitiello, who in April left his post


AIDS Group Says More Focus Needs to Be Put on Prevention - Expanded Access to Drugs Could Lead People at Risk To Let Their Guards Down
Wall Street Journal - June 11, 2004
Marilyn Chase, Staff Reporter of The Wall Street Journal
A group spearheaded by the Bill and Melinda Gates Foundation is warning that the drive to expand access to AIDS drugs could backfire, fueling growth of HIV infections, if treatment isn t paired with efforts to prevent the spread of infections. Amid the push to expand lifesaving drugs world-wide, prevention has gotten s


Copenhagen on Kyoto
Wall Street Journal - June 11, 2004
What do you get when you put eight of the world s most prominent economists in a room together for a week with a list of 10 global problems? In the case of the Copenhagen Consensus, a surprising amount of good sense. In a day when so many illuminati are fretting over global warming, it s easy to forget that most of the


Gates-Led Group Stresses Prevention in AIDS Effort
Wall Street Journal - June 10, 2004
Marilyn Chase, marilyn.chase@wsj.com
A group spearheaded by the Bill and Melinda Gates Foundation is warning that the push to expand access to AIDS treatment could backfire badly, fueling growth of HIV infections, if treatment isn t paired with efforts to prevent the spread of new infections. Amid the push to expand lifesaving drugs around the world, prev


Biotech: A high-risk gamble - With $40 billion in net losses, industry generally is an unsafe bet for staid investors
Wall Street Journal - June 7, 2004
David P. Hamilton
NEW YORK - Since the first biotechnology company went public a quarter-century ago, stock-market investors have put somewhere close to $100 billion into the industry. The results so far: More than a hundred new drugs and vaccines, several hundred million people helped by biotech medicines -- and cumulative net losses o


'Google Grants' Program Brings Questions From Those Left Out
Wall Street Journal - June 3, 2004
Carl Bialik, carl.bialik@wsj.com
As investors wait for more news on Google Inc. s planned IPO, nonprofit groups are anxious for word about the tight-lipped company s Google Grants advertising program. Under the program, Google has donated advertising space to hundreds of nonprofit groups tackling issues ranging from endangered species to multiple scle


Jack Valenti Will Lobby For AIDS Fight
Wall Street Journal - June 3, 2004
Rachel Zimmerman, rachel.zimmerman@wsj.com
The giant Global Fund to Fight AIDS, Tuberculosis and Malaria, facing a shortfall in its world-wide fund raising, is turning to Washington insider Jack Valenti for help. The film industry s prominent lobbyist since the mid-1960s, Mr. Valenti expects to announce today that he is taking a new job as president of a ventur


Planning Ahead: Stem-Cell Banks For the Healthy
Wall Street Journal - June 2, 2004
Rhonda L. Rundle, rhonda.rundle@wsj.com
Add this to the list of things to save for a rainy day: your own blood stem cells. Capitalizing on the emergence of stem-cell therapy as standard treatment for many kinds of leukemia and lymphoma , a company called NeoStem Inc. wants healthy consumers to pay $5,000 to bank their own stem cells for the future, to be use


Aetna Withdraws Antitrust Suit Against Abbott Over Drug Price
Wall Street Journal - May 28, 2004
Leila Abboud, leila.abboud@wsj.com
Aetna Inc. abruptly withdrew a federal antitrust lawsuit it filed on Tuesday against Abbott Laboratories over the pharmaceutical company s fivefold price increase on an HIV drug. Aetna declined to say why it withdrew the suit, saying it intends to discuss with Abbott the basis for its repricing action. The health


Drug-Pricing Rules Face Review
Wall Street Journal - May 24, 2004
Leila Abboud, leila.abboud@wsj.com
For the first time, the U.S. government will weigh whether it can require drug companies to lower prices on drugs developed with the help of taxpayer dollars. The question, which will be debated tomorrow at a U.S. National Institutes of Health meeting, was sparked by Abbott Laboratories 400% price increase on one of it


Panacos Gains $18.3 Million
Wall Street Journal - May 18, 2004
Panacos Pharmaceuticals Inc., Gaithersburg, Md., gained $18.3 million in series C funding. The round was led by Ampersand Ventures and A.M. Pappas & Associates and included Mitsui & Co. Venture Partners Inc., Novo A/S, New England Partners Capital LP, William Harris Investors, Lakeview Capital Management and th


U.S. Says 3-in-1 AIDS Drugs For Poor Nations Need Review
Wall Street Journal - May 17, 2004
Sarah Lueck, sarah.lueck@wsj.com
WASHINGTON - The Bush administration said 3-in-1 AIDS drugs must win Food and Drug Administration approval before the U.S. buys them for developing countries, prompting criticism from advocacy groups who called the process an unnecessary barrier. FDA officials said the process would be simple and speedy, perhaps taking


Scientists Warn of a Visa 'Crisis'
Wall Street Journal - May 13, 2004
Antonio Regalado, Staff Reporter of The Wall Street Journal
Leading U.S. scientific societies called on the Bush administration to solve what they termed a visa crisis that is keeping foreign students out of the country and may cause enrollments to drop. Twenty-five associations, including the Association of American Universities and the American Association for the Advancement


Abbott Laboratories Faces Heat Over Raising Price of AIDS Drug
Wall Street Journal - May 13, 2004
Leila Abboud, Staff Reporter of The Wall Street Journal
Abbott Laboratories is facing mounting pressure from activists, members of Congress and the federal government over its nearly fivefold price increase on its AIDS drug Norvir . The National Institutes of Health will hold a public meeting in Washington May 25 to consider whether the federal government


WHO Appeals for Coordination In Plan to Provide AIDS Drugs
Wall Street Journal - May 12, 2004
Gautam Naik, Staff Reporter of The Wall Street Journal
LONDON -- In the fight against AIDS, donor groups and public-health agencies need to coordinate their efforts in order to quickly provide drugs to desperately sick patients, concludes a report by the World Health Organization . Although countries, donors and other funding groups have pledged about $20 billion to stop t


Foreign Adoptions Add Layer of Health Concerns
Wall Street Journal - May 11, 2004
Francesco Fiondella, Staff Reporter of The Wall Street Journal
Last month, the Centers for Disease Control and Prevention temporarily suspended adoption processing from an orphanage in China s Hunan Province, after determining that it was the source of nine measles cases in recently adopted children. This was the second time since 1997 that the agency suspended adoptions from abro


Sixteen Nations to Get Initial Millennium Aid
Wall Street Journal - May 7, 2004
Michael Schroeder, Staff Reporter of The Wall Street Journal
WASHINGTON - The Bush administration selected 16 developing countries, half of them in Africa, that qualify for U.S. aid under a new program that links contributions to the countries record of political and economic reforms. The Millennium Challenge Corp., announced by President Bush two years ago in Monterrey,


Group Shifts Its Focus in AIDS Fight
Wall Street Journal - May 3, 2004
Marilyn Chase, Staff Reporter of The Wall Street Journal
NEW DELHI - The beat of a dhola, a Punjabi drum, drew a crowd to a white tent set up on the G.B. Road, this city s red-light district. A theater troupe belted out a Hindi movie theme song. A magician in red hair and blue eyeliner opened his bag of tricks. AIDS prevention programs often put the focus on prostitutes. On


Gates Foundation Bets It Can Stem India's AIDS Crisis
Wall Street Journal - May 3, 2004
Marilyn Chase, Staff Reporter of The Wall Street Journal
$200 Million Program Uses Franchised Health Clinics To Reach Groups at Risk Controversy Over Projections MYSORE, India -- At sundown one recent evening, a team of health workers piled into a sport-utility vehicle and roamed the streets of this city once ruled by a maharaja. Their marching orders came from software mogu


As Horror Recedes In Time, Rwanda Still Restrains Press
Wall Street Journal - April 30, 2004
Yaroslav Trofimov, Staff Reporter of The Wall Street Journal
Media Played a Major Role In Nation s 1994 Genocide; A Paper s Struggle Today Things We Cannot Say KIGALI, Rwanda - Charles Kabonero, a skinny 23-year-old in a Voice of America T-shirt, is the fourth managing editor in the three-year history of Rwanda s only independent newspaper. His predecessors all fled into exi


European Patients Lobby EC To Ease Its Ban on Drug Ads
Wall Street Journal - April 30, 2004
Jeanne Whalen, Staff Reporter of The Wall Street Journal
LONDON - When Ken Williams s HIV count began to soar last summer, he went online looking for help. Suffering from a chronic cough and incapacitating fatigue, he stumbled upon a Web site advertising a new AIDS medicine called Fuzeon. After he took the drug for two weeks, his viral count plummeted, and he rejuvenated.


White House Aims To Answer Critics Of Its AIDS Fight
Wall Street Journal - April 29, 2004
Sarah Lueck, Staff Reporter of The Wall Street Journal
WASHINGTON -- The Bush administration is working to develop a speedy approval process for combination AIDS treatments that could be used in developing countries, senior officials say. The administration hopes to calm a controversy over whether it will allow its multibillion-dollar global AIDS fund to be spent on cheape


Serono Faces Intensified Scrutiny On Marketing of Its AIDS Drug
Wall Street Journal - April 15, 2004
Christopher Windham, Staff Reporter of The Wall Street Journal
Federal and state officials are intensifying their investigations into Serono SA s marketing practices of an AIDS drug, several people familiar with the matter said. Serono s growth hormone Serostim is approved to treat AIDS-associated wasting. The government Medicaid program pays for most of the cost of the drug used


Big Donors in Global AIDS Fight Agree to Buy Generic Medicines
Wall Street Journal - April 6, 2004
Sarah Lueck, Staff Reporter of The Wall Street Journal
WASHINGTON -- Large contributors to AIDS-treatment programs in developing countries agreed to buy cheaper generic drugs, stepping into a simmering debate over whether the U.S. s multibillion-dollar AIDS fund also will buy them. The Global Fund, the World Bank and Unicef joined the Clinton Foundation in making arrangeme


Transplant of Animal Organs To Humans Could Pose Risks
Wall Street Journal - April 1, 2004
Mark Ingebretsen
At first glance, the idea of xenotransplantation sounds appealing. You can genetically modify another animal such as a pig so that its kidneys or other organs may be transplanted into humans who need them. But some experts worry that transferring genetic material from other animals to humans could introduce new disease


There's No Such Thing As a Free HIV Cocktail
Wall Street Journal - April 30, 2004
Mary Anastasia O'Grady
Back in the late 1990s, Brazil s monetary plan pegging the real to the dollar was hanging by a thread. A liberal Brazilian economist painted me a grim picture about his country s future. The dark clouds foretold not a looming catastrophe, he maintained, but rather perpetual mediocrity. So far, my soothsayer hasn t been


AIDS Epidemic Now Afflicts Broader Range of Americans
Wall Street Journal - March 30, 2004
Mark Ingebretsen
AIDS now afflicts a broader range of Americans, from teenagers who account for a disturbing portion of new HIV infections to poor Latino- and African-Americans, who make up the bulk of AIDS victims -- and even seniors, many of whom contract the virus late in life. The face of AIDS used to be a gay white male. Today it


J&J to Give Away New AIDS Drug: Nonprofit Group to Receive Royalty-Free Deal For Access to Experimental Medicine
Wall Street Journal - March 29, 2004
Christopher Windham, Staff Reporter of The Wall Street Journal
In a move to get an experimental medicine to impoverished developing-world markets, Johnson & Johnson will give away a promising AIDS drug to a nonprofit organization. Today, the International Partnership for Microbicides plans to announce it has reached a royalty-free agreement with Tibotec Pharmaceuticals Ltd., a


White House Gets Pressure on AIDS Plan: Activists, Drug Firms Duel Over Use of Funds For Generic Combination Drugs in Africa
Wall Street Journal - March 25, 2004
Sarah Lueck, Staff Reporter of The Wall Street Journal
WASHINGTON -- Caught between its allies in the drug industry and its promises to battle AIDS in Africa, the Bush administration is facing mounting pressure to allow its multibillion-dollar AIDS fund to spend money on generic combination drugs in Africa. The generic drugs cost just a fourth as much as their name-brand


Human Genome's Chief Is to Retire
Wall Street Journal - March 25, 2004
Scott Hensley, Staff Reporter of The Wall Street Journal
William Haseltine, a founder of Human Genome Sciences Inc., said he will retire as chairman and chief executive later this year, as the once-highflying biotechnology concern retrenches. Also, the Rockville, Md., company announced Thursday that it will focus on only five experimental medicines that are its strongest con


In Indonesia, AIDS Education Clashes With Islam: As Disease Rapidly Spreads, Fundamentalist Clerics Stifle Safe-Sex Message
Wall Street Journal - March 25, 2004
Cris Prystay And Timothy Mapes, Staff Reporters of The Wall Street Journal
Actress s Provocative New Role JAKARTA -- When Indonesian movie star Nurul Arifin speaks to community groups about HIV and AIDS, she aims to shock: She slips a condom over a prosthetic penis and explains in slang-laced language why people need to protect themselves against an incurable disease. But when leaders of some


Hit and Miss: Searching For Healthy Returns In Small Biotechs
Wall Street Journal - March 9, 2004
Christopher Oster, Staff Reporter of The Wall Street Journal
Separate HIV Treatments Brought Success to Gilead, But Trimeris Faces Hurdles For Kris Jenner, finding the right drug at the right company can mean the difference between healthy returns and a pox on the portfolio. Mr. Jenner, manager of T. Rowe Price Health Sciences Fund, tries to get a leg up on its rivals by finding


When Hospitals Were Places Only the Poor Could Afford to Enter
Wall Street Journal - March 3, 2004
Cynthia Crossen
In 1869, a group of women from St. John s Episcopal Church in Yonkers, N.Y., founded a hospital for their parish s deserving poor. That hospital still exists. Today, it s a multimillion-dollar business. When St. John s Invalid Home, as it was known then, began filling its 30 beds, only the poor would risk their lives g


Merck Still Draws Fire for HIV Drug For Poor Nations
Wall Street Journal - March 3, 2004
Rachel Zimmerman, Staff Reporter of The Wall Street Journal
More than a year after Merck & Co. drew praise from AIDS activists for offering a reduced-price version of an important new HIV drug for poor countries, the medicine hasn t been approved for sale in many of the nations hard hit by the epidemic. Only 100,000 of the 4.4 million people in need of antiretroviral therap


Scientists Identify Monkey Protein That Blocks AIDS
Wall Street Journal - February 26, 2004
Marilyn Chase, Staff Reporter of The Wall Street Journal
Scientists said they identified a protein that shields rhesus monkeys from the AIDS virus, a finding that opens new avenues for drug and vaccine research. The protein, called TRIM5-alpha, is believed to be part of the innate immune system that patrols the body looking for invaders and blocks their ability to infect.


Saying No to 'Sugar Daddies': Can a Financial Prophylactic Shield Girls From Liaisons That Spread AIDS in Africa?
Wall Street Journal - February 25, 2004
Marilyn Chase, Staff Reporter of The Wall Street Journal
Backed by $5 million in grants from the U.S. National Institutes of Health, California researchers are testing a new AIDS prevention tool in Zimbabwe -- a financial prophylactic aimed at shielding young girls from sexual liaisons that transmit the virus. The program, Shaping the Health of Adolescents in Zimbabwe, or SH


Drug Industry's Big Push Into Technology Falls Short: Testing Machines Were Built To Streamline Research -- But May Be Stifling It
Wall Street Journal - February 24, 2004
Peter Landers, Staff Reporter of The Wall Street Journal
A decade ago, pharmaceutical companies announced a revolutionary new way of finding drugs. Instead of relying on scientists hunches about what chemicals to experiment with, they brought in machines to create thousands of chemical combinations at once and tested them out with robots. The new technology was supposed to b


U.S. Issues Grants in AIDS Battle: White House Dedicates $350 Million to Global Effort; Generics Issue Is Unresolved
Wall Street Journal - February 24, 2004
Sarah Lueck and Michael M. Phillips, Staff Reporters of The Wall Street Journal
WASHINGTON - The Bush administration announced the first $350 million in grants for an initiative to fight AIDS around the world, doling out funds to reduce mother-to-child transmission of the disease, treat those who are ill and promote sexual abstinence. Administration officials said Monday s announcement demonstrate


Russia's Health Care Is Crumbling: Dire Lack of Funds Creates Sick, Dwindling Populace And 'National Emergency'
Wall Street Journal - February 13, 2004
Jeanne Whalen, Staff Reporter of The Wall Street Journal
RZHEV, Russia -- Alexei Serov knew it was time to evacuate the pregnant mothers from his maternity hospital in central Russia when pipes began bursting and plaster started falling off walls. Health regulators closed the clinic, which hadn t been renovated in 40 years, and Dr. Serov moved his patients to a makeshift war


Roche Drugs Show Promise For Treating AIDS, Hepatitis
Wall Street Journal - February 12, 2004
Gautam Naik, Staff Reporter of The Wall Street Journal
LONDON -- Roche Holding AG said a trial of a two-drug combination to treat patients infected with both HIV and hepatitis C showed marked and sustained reductions in viral levels. The Swiss pharmaceutical company said a combination of its drugs Pegasys and Copegus had yielded a 40% sustained virological response in a tr


Data on New AIDS Drug Are Upbeat: Schering-Plough Therapy Blocks Virus Ability to Bind To Receptor on Human Cells
Wall Street Journal - February 12, 2004
Marilyn Chase, Staff Reporter of The Wall Street Journal
SAN FRANCISCO -- Hopeful findings on a new oral AIDS drug called Schering D from Schering-Plough Corp. put the spotlight on a newly identified Achilles heel of the virus. Researchers from the Kenilworth, N.J., drug company presented new data from a study at Berlin s Charite Hospital testing Schering D pills in a placeb


It's Back to Basics After Setbacks For AIDS Vaccine
Wall Street Journal - February 12, 2004
Marilyn Chase, Staff Reporter of The Wall Street Journal
SAN FRANCISCO -- In the wake of setbacks in AIDS-vaccine trials, scientists made a plea for vaccine researchers to go back to their labs and settle basic science questions about the complex interplay between the AIDS virus and the human immune system. There s ample evidence to indicate that development of an effective


Nearly 4% of New York City Men In Their 40s Are Infected With HIV
Wall Street Journal - February 11, 2004
Marilyn Chase, Staff Reporter of The Wall Street Journal
SAN FRANCISCO -- Nearly 4% of New York City men aged 40 to 49, and almost 3% of all adult men residing in Manhattan, are infected with HIV or have full-blown AIDS, according to new data released by the New York City Department of Health and Mental Hygiene. Harold Jaffe, who heads HIV prevention programs at the U.S. Cen


Efforts to Stem Mother-to-Child AIDS Transmission Hit Obstacles
Wall Street Journal - February 10, 2004
Marilyn Chase, Staff Reporter of The Wall Street Journal
SAN FRANCISCO -- The drive to find simpler and cheaper AIDS drug regimens has a high price tag -- the development of viral resistance in many users. Nowhere has this arisen more starkly than with an antiviral drug used to prevent mother-to-child transmission of the immunodeficiency virus. Giving a mother a single dose


Ask Before You Leap
The Wall Street Journal - January 26, 2004
Geeta Anand, Staff Reporter of The Wall Street Journal
If you re thinking of joining a clinical trial for experimental drugs, make sure to get the answers to these questions Tens of thousands of patients each year enroll in clinical trials of experimental drugs and devices. Some join these studies to advance medicine for future generations, others because they hope to pers


Steeped in Confusion
Wall Street Journal - January 26, 2004
Jennifer Saranow
Five years ago, Elisa Albert visited a Los Angeles tea garden where the menu associated the beverage with benefits such as improved memory and curing colds. She has been drinking tea ever since. I started thinking about tea as a health thing, says the 25-year-old graduate student in New York. She currently has 18 boxes


Breakthrough!
Wall Street Journal - January 26, 2004
Tara Parker-Pope
Ten major medical advances you re likely to see in the coming year Another day, another medical breakthrough. So it seems, as each week brings fresh reports of miracle drugs, groundbreaking studies, revolutionary surgical procedures. But with so much hype around so many medical discoveries, how do we know which ones we


The Gender Gap
Wall Street Journal - January 26, 2004
Andrew Blackman
Scientists are discovering crucial differences between men and women in a variety of health areas. For doctors and patients, it s about time. Aggie Landry was lucky. The 38-year old mother of three from Dallas was only a couple of blocks from a hospital when she had her heart attack last April, and was quickly rushed i


Noted Researcher Retracts Finding on AIDS Immunity
Wall Street Journal - January 22, 2004
Marilyn Chase, Staff Reporter of The Wall Street Journal
Forget about that highly touted clue to the most enduring mystery of the AIDS epidemic -- why some people infected with the human immunodeficiency virus never develop the disease. In a rare published retraction in the journal Science, researcher David Ho, the AIDS world s nearest thing to a rock star, says he erred in


Review & Outlook: WHO's Bad Medicine
Wall Street Journal - January 21, 2004
For a cautionary tale on using politicized international aid organizations to combat Third World disease, we encourage someone in the Bush Administration to grab a copy of this week s Lancet, the British medical journal. The magazine reports that United Nations-led efforts to treat malaria victims in Africa have actual


WHO Plans to Target Increases In HIV, Tuberculosis Co-Infections
Wall Street Journal - January 21, 2004
Gautam Naik, Staff Reporter of The Wall Street Journal
LONDON -- The World Health Organization intends to announce Wednesday a plan for reducing the runaway increases in HIV and tuberculosis co-infections, one of the leading causes of death in Africa. HIV weakens the immune system and makes a person more susceptible to TB. If untreated for TB, a co-infected patient usually


Cracking Down On Illicit Use Of AIDS Drug
Wall Street Journal - January 19, 2004
Christopher Windham, Staff Reporter of The Wall Street Journal
Law-enforcement crackdowns across the country are starting to stem the tide of an unusual type of contraband: an AIDS medication that has found an underground recreational use as a bodybuilding drug. The drug is Serostim , a growth hormone prescribed to fight the wasting syndrome that can affect AIDS patients.


AIDS Vaccine Test in Thailand Reveals Split Among Scientists
Wall Street Journal - January 16, 2004
David P. Hamilton And Marilyn Chase, Staff Reporters of The Wall Street Journal
In the latest controversy over devoting research funds to hunt for an AIDS vaccine, a group of 22 leading researchers have criticized a major test under way in Thailand . The critique, published Friday in the journal Science, takes aim at the $119 million test involving 16,000 Thai volunteers. The research group conten


HIV-Test Makers Agree To Discounts for Poorer Nations
Wall Street Journal - January 14, 2004
Mark Schoofs, Staff Reporter Of The Wall Street Journal
Former President Bill Clinton s Foundation plans to announce Wednesday a deal with five of the world s leading medical companies to slash the price of two critical HIV diagnostic tests in developing nations. The agreement comes on the heels of a landmark deal the Clinton Foundation and several generic-drugs companies s


Costly New Drug For AIDS Means Some Go Without: Programs for the Uninsured Are Facing Tough Choices With Advent of Fuzeon
Wall Street Journal - January 13, 2004
Vanessa Fuhrmans, Staff Reporter of The Wall Street Journal
RALEIGH, N.C. -- North Carolina doctors and health officials met last year to tackle a wrenching dilemma. Roche Holding AG s new AIDS drug, called Fuzeon, was beating the toughest strains of the virus, giving patients who didn t respond to other medicines a new chance to live. But at roughly $20,000 a year, it costs th


Merck's Top AIDS Researcher Joins Nonprofit Vaccine Effort
Wall Street Journal - January 13, 2004
Marilyn Chase, Staff Reporter of The Wall Street Journal
In a major loss to Merck & Co. s AIDS program, one of the company s top AIDS researchers will leave at the end of this month to join a nonprofit group funding the drive to develop a vaccine to halt the epidemic. Emilio Emini, 50 years old, Merck s senior vice president of vaccine research and the father of its anti


Researchers Try to Cut New Path to Pharmacy: As Companies Get Gun Shy, Nonprofits Make Drugs And Conduct Own Trials
The Wall Street Journal - January 12, 2004
Sharon Begley, Staff Reporter
MEMPHIS, Tenn. -- By the late 1990s, scientists Karen Slobod and Julia Hurwitz of St. Jude Children s Research Hospital here had an experimental AIDS vaccine on the drawing board unlike any other. It showed great promise in the test tube and in animals such as mice, rabbits and chimpanzees. But not one of the drug comp



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©1980, 2004. AEGiS.