AEGiS-UPI: Silencing a protein might prevent leukemia United Press InternationalImportant note: Information in this article was accurate in 2008. The state of the art may have changed since the publication date.
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Silencing a protein might prevent leukemia

United Press International - October 22, 2008


HERSHEY, Pa., Oct. 22 (UPI) -- U.S. medical scientists say blocking signals from a specific protein might help kill cells that cause a rare form of blood cancer.

The team of physicists and oncologists say their discovery could provide more efficient ways of targeting diseases such as leukemia, and help in the potential development of vaccines for viruses that cause AIDS.

Dr. Thomas Loughhran, the study's lead author and director of Pennsylvania State University's Hershey Cancer Institute, and his Penn State colleagues are trying to determine the conditions that cause an abnormal expansion of T-cells and trigger a disease known as large granular lymphocyte leukemia.

The complex research that included graduate students Ranran Zhang and Mithun Shah, Assistant Professors Dr. Jun Yang, Susan Nyland and Xin Liu, along with Associate Professor Jong Yun, is reported in the Proceedings of the National Academy of Science.


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