Important note: Information in this article was accurate in 2007. The state of the art may have changed since the publication date.
United Press International - October 1, 2007
Researchers at Thomas Jefferson University Medical Center said microRNA, or miRNA, better known for its roles in cancer, could be a key to unlocking the secrets of how HIV -- the AIDS virus -- hides in the immune system.
The researchers discovered when an individual infected with HIV receives a powerful cocktail of antiviral agents called HAART -- Highly Active AntiRetroviral Therapy -- the virus calls on miRNAs to help it remain quiet and practically undetectable, temporarily shutting down its ability to replicate and infect.
The work led by Dr, Hui Zhang, an associate professor of medicine, appears in the early online edition of the journal Nature Medicine.
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