AEGiS-UPI: AIDS twins show different immune response United Press InternationalImportant note: Information in this article was accurate in 2005. The state of the art may have changed since the publication date.
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AIDS twins show different immune response

United Press International - December 6, 2005


LOS ANGELES - Scientists in California have found that identical twins infected with AIDS shortly after birth have a different immune responses.

The brothers received blood transfusions from the same donor in 1983. They continued to live in Los Angeles and were subjected to the same environmental factors.

In spite of having an identical genetic makeup and being infected with the same strain of HIV virus, the boys' T-cell receptors acted differently, scientists at UCLA say.

"These boys are as similar as two humans can be, yet we see differences in how they fight the virus," said Dr. Paul Krogstad, professor of pediatrics and pharmacology, and one of the researchers. "That's one more thing that makes it difficult to develop a vaccine for everyone."


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