AEGiS-UPI: Vaginal HIV vaccine being studied United Press InternationalImportant note: Information in this article was accurate in 2005. The state of the art may have changed since the publication date.
Click here to return to United Press International main menu
DonateNow
Print this article




Vaginal HIV vaccine being studied

United Press International - September 22, 2005


BELFAST, Northern Ireland (UPI) -- Researchers in Northern Ireland are investigating a new approach to fighting HIV, a vaginal vaccine that would work over the course of a year.

The research is being conducted by a team from Queen's University in Belfast and is funded by a $2.3 million grant from funds given to St. George's Hospital Medical School in London by the Bill and Melinda Gates Foundation and the Wellcome Trust.

Professor David Woolfson of the School of Pharmacy at Queens said the vaccine -- probably topical rather than injected -- will target the immune cells in the lining of the vagina.

"It is hoped that continuous, controlled vaginal delivery of such a specially engineered vaccine, which has never been tried before, will provide immunity where it is most needed, at the site of viral entry, and in turn induce whole body immunity," Woolfson told the BBC.

Woolfson said conventional immunization just does not seem to work for HIV because the virus mutates so rapidly.

"Continuous vaccine delivery to induce immunity where the virus first enters the body is an exciting concept but it will take time, multi-disciplinary scientific skills and not a little good fortune to achieve," he said.


050922
UP050907


Copyright © 2005 - United Press International. All rights reserved. Reproduced with permission. Reproduction of this article (other than one copy for personal reference) must be cleared through United Press International, Permissions Desk, 1510 H St. N.W. Washington DC 2005. Main Phone Switchboard: 202-898-8000 FAX: 202-898-8057 or 202-898-8147 Email: info@upi.com.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Elton John AIDS Foundation UK, the National Library of Medicine, AIDS Walk of Orange County, and donations from users like you.

Always watch for outdated information. This article first appeared in 2005. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 2005. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .