Important note: Information in this article was accurate in 2004. The state of the art may have changed since the publication date.
|
|
United Press International - Friday, July 9, 2004
Researchers from the National Institutes of Health and the Institut de Recherche pour le Developpement in Paris reported a single dose of nevirapine given to a woman at the beginning of labor, when combined with a short course of the HIV drug AZT, reduced transmission of HIV to below 2 percent, similar to more expensive three-drug regimens used in developed countries.
In a second study, Harvard researchers also found some women who received nevirapine developed nevirapine-resistant HIV strains that faded away with time, but the women did not respond as well to later nevirapine treatment.
articipants in the first study received one of three regimens -- the standard AZT treatment plus single doses of nevirapine to mother and child, a single dose of nevirapine to the mother and a placebo to the child, or placebos to both mother and child.
Both studies included women from Thailand. The transmission rate for the AZT only group was 6.3 percent before that arm of the study was halted because it became apparent nevirapine combo treatment was much more effective, researchers said.
040709
UP040709
Copyright © 2004 - United Press International. All rights reserved. Reproduced with permission. Reproduction of this article (other than one copy for personal reference) must be cleared through United Press International, Permissions Desk, 1510 H St. N.W. Washington DC 2005. Main Phone Switchboard: 202-898-8000 FAX: 202-898-8057 or 202-898-8147 Email: info@upi.com.
AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Elton John AIDS Foundation UK, the National Library of Medicine, AIDS Walk of Orange County, and donations from users like you.
Always watch for outdated information. This article first appeared in 2004. This material is designed to support, not replace, the relationship that exists between you and your doctor.
AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.
Copyright ©1980, 2004. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .