AEGiS-UPI: NEW AIDS VIRUS FOUND DIFFERENT FROM FIRST United Press InternationalImportant note: Information in this article was accurate in 1986. The state of the art may have changed since the publication date.
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NEW AIDS VIRUS FOUND DIFFERENT FROM FIRST

United Press International - December 18, 1986


Scientists at the Pasteur Institute in France said yesterday that they had cloned a newly discovered virus that can cause AIDS in humans and determined that it was quite different from the main AIDS virus and somewhat similar to a third virus that causes the disease in monkeys.

They also said the obscure HIV-2 virus, discovered this year in West African AIDS patients, was signficantly different from HIV-1, also called HTLV-3 and LAV-1, the virus identified as the primary cause of the deadly acquired immune deficiency syndrome.

"They are very, very different viruses but they both cause AIDS in humans," said a Pasteur spokesman, Caroline Chaine, in a telephone interview from Lille, France.

The Pasteur team, led by a top AIDS researcher, Luc Montagnier, reported their findings in the British science journal Nature.

Mr. Montagnier said through a spokesman that he was not sure of the significance of his discovery and that scientists still had a long way to go before determining the origin of the mysterious disease.

Miss Chaine said researchers suspected the two human AIDS viruses were different because a test to determine the presence of the HTLV-3 virus in humans did not indicate the presence of the HIV-2 virus.

"You must use separate tests," she said. "So we knew they were probably different viruses even though the disease is exactly the same."

But the cloning of the HIV-2 virus, accomplished two months ago, proves the molecular makeup of the two viruses are significantly different.

Miss Chaine said cloning had shown that HIV-2 was more closely related to a virus known to cause AIDS in macaque monkeys than the original HTLV-3 virus.

"But they are still different," she said of the human and monkey viruses. "It doesn't tell us very much."


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