United Press International - December 11, 1986
In a report that challenges prevailing views of how AIDS develops, the researcher, Dr. John Ziegler, said scientists might have to develop drugs that suppress the immune system rather than enhance it.
Dr. Ziegler, director of the AIDS Research Center at the University of California in San Francisco, writing in the medical journal Clinical Immunology and Immunopathology, suggested that the virus triggers the disease when it tries to mimic the tiny portions on certain immune system cells that the body recognizes as "self."
When the body mounts an attack against the virus it mistakenly attacks these cells as well as the virus, he said.
"Internal mutiny is triggered by this virus," said Dr. Ziegler, "because what you see in the early stages of AIDS isn't an immune deficiency but an immune system in overdrive."
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