AEGiS-Reuters: Merck cancels a HIV protease inhibitor test

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Merck cancels a HIV protease inhibitor test

Reuters NewMedia, Inc.; Friday September 18, 1998


WHITEHOUSE STATION, N.J., Sept 18 (Reuters) - Merck & Co. Inc. said Friday it had discontinued the evaluation of twice-daily dosing regimens of its HIV protease inhibitor, Crixivan, in combination with reverse transcriptase inhibitors.

Merck recommends that patients in the twice-daily dosing arms in these studies be changed to a regimen with the approved dosing of Crixivan to ensure that they receive optimal therapy, it said in a statement.

Merck will continue to study twice-daily dosing of Crixivan in combination trials with other protease inhibitors.

Crixivan in combination with other antiretroviral agents is used for the treatment of HIV infection.
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