AEGiS-Reuters: Gilead finds Preveon helps cut HIV RNA

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Gilead finds Preveon helps cut HIV RNA

Reuters NewMedia, Inc.; Wednesday, July 1, 1998


FOSTER CITY, Calif., July 1 (Reuters) - Gilead Sciences Inc. said on Wednesday that its Preveon drug when used with other drugs showed a decrease in levels of HIV genetic material when tested in Phase II/III clinical trials.

In data presented to the 12th World AIDS Conference in Geneva, once-daily treatment with Preveon as part of combination regimens was associated with a decline in HIV RNA at week 24 that was maintained through week 48, the company said in a statement.

No change was observed in the placebo group at week 24, the company said about the study involving 442 patients.

The patients received treatment with either once-daily Preveon or a placebo in addition to any approved anti-HIV treatment regimen, Gilead said. The study was placebo controlled for 24 weeks, followed immediately by a 24 week open-label phase during which all continuing patients received Preveon.


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