AEGiS-Reuters: Immune signs pact with Agouron

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Immune signs pact with Agouron

Reuters NewMedia, Inc.; Thursday June 11, 4:38 pm EST


LA JOLLA, Calif., June 11 (Reuters) - Immune Response Corp said Thursday it signed a pact with Agouron Pharmaceuticals for final development and commercialization of HIV treatment REMUNE worth up to $77 million to Immune Response over two years.

REMUNE is an immune-based therapy for the treatment of HIV infection which was discovered by Immune Response and is in phase III clinical trials. The two companies plan to complete development and apply for registration of REMUNE in 1999.

Under the agreement Immune Response will make commercial supplies of the drug and Agouron will have exclusive rights to market it in North America, Europe, as well as in certain other countries.

Immune Response may receive as much as $77 million over the next two years, including license and milestone payments of $45 million, payments to support development of $18 million, and the purchase of $14 million of Immune Response common stock at a premium to market, the company said in a statement.

The two companies will equally share all profits from the commercialization of REMUNE.

"We made the decision to aggressively pursue this opportunity with Immune Response after a comprehensive review of clinical data on REMUNE from a number of studies, which convinced us of the unique potential of this product to make a powerful contribution to the treatment of HIV infection and AIDS," said Agouron's President and Chief Executive Peter Johnson.

REMUNE is an immune-based therapy, derived from HIV itself, which has been shown to elicit an HIV-specific immune response.


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