Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.
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Reuters NewMedia, Inc. - Thursday, November 21, 1996
The Centers for Disease Control and Prevention (CDC) said the change came because more pregnant women were tested for HIV and, if the test was positive, took the drug zidovudine (AZT) to reduce the chance of transmitting it to their babies.
It estimated that 663 newborn infants acquired AIDS from their mothers in 1995. The figure has been declining every year since 1992, when 905 infants were diagnosed as perinatally infected.
"We have seen, particularly in the Northeast and the South, declines in perinatal AIDS cases," said Dr. Mary Lou Lindegren of the surveillance branch of the CDC's Division of HIV/AIDS Prevention.
The CDC said the reduction in perinatal AIDS cases probably occurred because more pregnant women underwent HIV counseling and voluntary testing and used zidovudine to prevent transmission of the AIDS virus to their babies.
There was a decline of 8 percent in perinatal AIDS cases among infants from 1993 to 1994 and a drop of 17 percent from 1994 to 1995. Lindegren called the decrease "extremely encouraging early news about the impact of Public Health Service recommendations for the use of zidovudine and women accepting HIV testing during pregnancy."
A CDC study found zidovudine use rose from 17 percent to 80 percent among HIV-infected pregnant women after the Public Health Service issued guidelines recommending the use of the drug during pregnancy and childbirth. The guidelines also urge that babies of HIV-infected women be given zidovudine for six weeks after birth.
Lindegren said it was not known if zidovudine's greatest value was in reducing viral transmission in the womb or during delivery or because it protects a newborn who might become infected through breast-feeding.
"We think most of the transmission occurs during labor and delivery," he said. Researchers found in 1994 that giving pregnant women zidovudine could reduce by two-thirds the chance they would transmit the AIDS virus to their babies.
As of Sept. 30, 566,002 AIDS cases had been reported to the CDC among all age groups including 7,472 among children under age 13. Ninety percent of children with AIDS were infected perinatally. The rest for whom a cause was known were infected through contaminated blood or blood products.
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