Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.
Important note: Information in this article was accurate in 1996. The state of the art may have changed since the publication date.
Reuters NewMedia, Inc. - 19 September 1996
A paper presented at the 36th Interscience Conference on Antimicrobial Agents and Chemotherapy by Dr Gary Garber of the University of Ottawa, said giving mice two injections of trichomonas vaginalis -- one month apart -- produced elevated antibodies in blood and vaginal secretions that do not occur after a natural vaginal infection.
"This may explain why women with a previous trichomonal infection are not apparently protected from reinfection,'' he reported. The two doses prevented or hastened eradication of subsequent vaginal infections.
"This work provides a compelling basis for the feasibility to develop a vaccine approach in women.''
According to Garber's report, an estimated 5 million women in the United States and 180 million worldwide are infected annually with trichomoniasis, a disease associated with increased HIV transmission in women and miscarriages.
In the Ottawa study, high innoculating doses provided more protection against the disease. For the next two to three years, researchers will be working to define the vaccine material that could be used on humans, the report said.
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